3PBP

structure of the yeast heterotrimeric nup82-nup159-nup116 nucleoporin complex

• Total interactions analyzed: 66
• Total true interactions: 19
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 114
  • Norm. En. per Res.: -3.5389
• Hub Node: B(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-73.705	-50.061	-279.666	-403.432	114	19	3	11048	2	45	13
A-C	-11.5666	-4.1714	-241.778	-257.516	85	12	12	10973	0	19	16
B-C	0.0	0.0	-0.1	-0.1	3	0	0	26	0	1	2
B-E	-6.2315	28.2997	-29.1033	-7.0351	34	0	0	1818	0	10	6
B-G	0.0	0.0	-0.5681	-0.5681	11	0	0	108	0	3	5
D-E	-61.072	-54.878	-271.755	-387.705	118	28	3	11371	3	42	13
D-F	-6.6947	-3.9674	-237.56	-248.222	84	10	12	10854	0	20	17
D-G	-2.3043	0.0	-37.9693	-40.2736	21	4	0	1478	0	0	0
E-F	0.0	0.0	-0.0693	-0.0693	3	0	0	19	0	1	2
E-G	0.0	0.0	-0.1549	-0.1549	2	0	0	15	0	1	1
G-H	-68.4141	-39.5593	-280.082	-388.0554	116	24	4	10894	2	44	12
G-I	-6.6866	-2.8267	-222.169	-231.6823	80	10	13	10176	0	21	21
G-J	0.0	17.8063	-37.642	-19.8357	39	0	0	1757	3	12	10
H-I	0.0	0.0	-0.146	-0.146	3	0	0	35	0	1	2
I-J	0.0	0.0	-27.1629	-27.1629	32	15	3	2341	0	4	12
I-K	-6.1842	6.3037	-6.4896	-6.3702	18	0	0	485	0	5	4
J-K	-68.0535	-43.1936	-255.069	-366.3161	113	22	3	10613	2	46	12
J-L	-14.3564	-3.0952	-236.354	-253.8056	81	12	13	10659	0	19	19
K-L	0.0	0.0	-0.1142	-0.1142	3	0	0	28	0	1	2

Interface residues

• A-B: ALA1035B, ALA1051B, ALA1109B, ALA1110B, ALA177A, ALA299A, ARG1066B, ARG1079B, ARG1083B, ARG178A, ASN1036B, ASN1048B, ASN1057B, ASN1089B, ASN1107B, ASN170A, ASN171A, ASN180A, ASN198A, ASN288A, ASN341A, ASN345A, ASN346A, ASP1062B, ASP176A, ASP181A, ASP204A, ASP296A, ASP320A, ASP340A, CYS1031B, CYS1055B, CYS1058B, GLN1075B, GLN282A, GLU1027B, GLU1111B, GLU201A, GLU293A, GLY1100B, GLY174A, GLY202A, GLY203A, GLY283A, GLY292A, HIS1074B, HIS1080B, HIS1108B, ILE1003B, ILE1024B, ILE1032B, ILE1033B, ILE1047B, ILE1053B, ILE1069B, ILE1105B, ILE205A, ILE287A, ILE325A, LEU1037B, LEU1076B, LEU1084B, LEU175A, LEU294A, LEU331A, LEU348A, LEU350A, LYS1029B, LYS1063B, LYS1067B, LYS1078B, LYS280A, PHE1005B, PHE1026B, PHE1056B, PHE1092B, PHE1104B, PHE173A, PHE206A, PHE285A, PHE290A, PHE319A, PRO1028B, PRO1038B, PRO1060B, PRO1088B, PRO284A, PRO289A, PRO291A, SER1064B, SER1090B, SER172A, SER347A, THR1025B, THR1030B, THR1065B, THR199A, THR200A, THR286A, THR298A, TYR1034B, TYR1059B, TYR1095B, TYR1102B, TYR295A, TYR297A, TYR342A, TYR344A, VAL1049B, VAL1061B, VAL1077B, VAL1106B, VAL343A, VAL349A
• A-C: ALA1442C, ALA390A, ALA406A, ARG353A, ASN1444C, ASN1455C, ASN1457C, ASN224A, ASN228A, ASN288A, ASN312A, ASN345A, ASN398A, ASN403A, ASP1451C, ASP308A, ASP330A, ASP401A, GLN1448C, GLN311A, GLU1438C, GLU235A, GLU313A, GLU332A, GLU352A, GLU399A, GLY1433C, GLY1440C, GLY1450C, GLY310A, GLY407A, HIS260A, ILE1449C, ILE226A, ILE287A, ILE351A, ILE397A, LEU1441C, LEU1456C, LEU225A, LEU227A, LEU231A, LEU253A, LEU327A, LEU331A, LEU348A, LEU350A, LEU393A, LEU402A, LEU405A, LEU408A, LYS1435C, LYS1446C, LYS1447C, LYS1454C, LYS221A, LYS229A, LYS329A, LYS395A, LYS409A, PHE1434C, PHE1452C, PHE1453C, PHE290A, PHE328A, PHE410A, PRO289A, PRO291A, PRO404A, SER230A, SER236A, SER347A, SER394A, SER396A, SER400A, THR1445C, THR286A, THR392A, TRP389A, TYR344A, VAL1436C, VAL1437C, VAL1439C, VAL232A, VAL349A
• B-C: LYS1454C, SER1064B, THR1065B
• B-E: ALA1097E, ASN1057E, ASN1073E, ASN967B, ASN969B, ASP1062E, ASP1071E, ASP1096E, ASP1098E, ASP977B, GLU968B, HIS1074E, ILE1069E, LEU1016B, LEU976B, LEU979B, LYS1067E, LYS1070E, LYS998B, PRO1015B, PRO1068E, PRO1072E, SER1099E, SER975B, SER980B, SER981B, SER983B, THR1017B, THR1065E, THR978B, TYR1059E, TYR970B, TYR971B, TYR982B
• B-G: ARG1040B, ARG358G, ARG988B, ASN449G, ASP416G, GLN357G, GLN382G, GLU415G, LEU414G, LEU985B, LYS1042B
• D-E: ALA1035E, ALA1051E, ALA1109E, ALA1110E, ALA177D, ALA299D, ARG1040E, ARG1066E, ARG1079E, ARG1083E, ARG178D, ASN1036E, ASN1048E, ASN1057E, ASN1087E, ASN1089E, ASN1107E, ASN170D, ASN171D, ASN180D, ASN198D, ASN288D, ASN341D, ASN345D, ASN346D, ASP1062E, ASP176D, ASP181D, ASP204D, ASP296D, ASP320D, ASP340D, CYS1031E, CYS1055E, CYS1058E, GLN1075E, GLN282D, GLU1027E, GLU1111E, GLU201D, GLU293D, GLY1100E, GLY174D, GLY202D, GLY203D, GLY283D, GLY292D, HIS1074E, HIS1080E, HIS1108E, ILE1003E, ILE1024E, ILE1032E, ILE1033E, ILE1053E, ILE1069E, ILE1105E, ILE205D, ILE287D, ILE325D, LEU1037E, LEU1076E, LEU1084E, LEU175D, LEU197D, LEU294D, LEU331D, LEU348D, LEU350D, LYS1029E, LYS1063E, LYS1067E, LYS1078E, LYS1086E, LYS1091E, LYS280D, PHE1005E, PHE1026E, PHE1056E, PHE1092E, PHE1104E, PHE173D, PHE206D, PHE285D, PHE290D, PHE319D, PRO1028E, PRO1038E, PRO1060E, PRO1088E, PRO169D, PRO284D, PRO289D, PRO291D, SER1064E, SER1090E, SER172D, SER347D, THR1025E, THR1030E, THR1065E, THR199D, THR200D, THR286D, THR298D, TYR1034E, TYR1059E, TYR1095E, TYR1102E, TYR295D, TYR297D, TYR342D, TYR344D, VAL1061E, VAL1077E, VAL1106E, VAL343D, VAL349D
• D-F: ALA1442F, ALA390D, ALA406D, ASN1444F, ASN1455F, ASN1457F, ASN224D, ASN228D, ASN288D, ASN312D, ASN345D, ASN398D, ASN403D, ASP1451F, ASP308D, ASP330D, ASP401D, GLN1448F, GLN311D, GLU1438F, GLU235D, GLU313D, GLU332D, GLU352D, GLU399D, GLY1433F, GLY1440F, GLY1450F, GLY310D, GLY407D, HIS260D, ILE1449F, ILE226D, ILE287D, ILE351D, ILE397D, LEU1441F, LEU1456F, LEU225D, LEU227D, LEU231D, LEU253D, LEU327D, LEU331D, LEU348D, LEU350D, LEU393D, LEU402D, LEU405D, LEU408D, LYS1435F, LYS1446F, LYS1447F, LYS1454F, LYS221D, LYS229D, LYS329D, LYS395D, LYS409D, PHE1434F, PHE1452F, PHE1453F, PHE290D, PHE328D, PHE410D, PRO289D, PRO291D, PRO404D, SER230D, SER236D, SER347D, SER394D, SER396D, SER400D, THR1445F, THR286D, THR392D, TRP389D, TYR344D, VAL1436F, VAL1437F, VAL1439F, VAL232D, VAL349D
• D-G: ALA15G, ALA9G, ARG44G, ASP238D, GLN14G, ILE12G, ILE250D, LEU10G, LEU237D, LEU445G, LEU7G, LYS246D, PHE13G, PRO11G, SER16G, SER239D, SER8G, THR240D, THR241D, TYR54G, VAL243D
• E-F: LYS1454F, SER1064E, THR1065E
• E-G: GLU968E, LYS443G
• G-H: ALA1035H, ALA1051H, ALA1109H, ALA1110H, ALA177G, ALA299G, ARG1040H, ARG1066H, ARG1079H, ARG1083H, ARG178G, ASN1036H, ASN1048H, ASN1057H, ASN1087H, ASN1089H, ASN1107H, ASN170G, ASN171G, ASN198G, ASN288G, ASN341G, ASN345G, ASN346G, ASP1062H, ASP176G, ASP181G, ASP204G, ASP296G, ASP320G, ASP321G, ASP340G, CYS1031H, CYS1055H, CYS1058H, GLN1075H, GLN282G, GLU1027H, GLU1111H, GLU201G, GLU293G, GLY1100H, GLY174G, GLY202G, GLY203G, GLY283G, GLY292G, HIS1074H, HIS1080H, HIS1108H, ILE1003H, ILE1024H, ILE1032H, ILE1033H, ILE1047H, ILE1053H, ILE1069H, ILE205G, ILE287G, ILE325G, LEU1037H, LEU1076H, LEU1084H, LEU175G, LEU294G, LEU331G, LEU348G, LEU350G, LYS1029H, LYS1063H, LYS1067H, LYS1078H, LYS168G, LYS280G, PHE1005H, PHE1026H, PHE1056H, PHE1092H, PHE1104H, PHE173G, PHE206G, PHE285G, PHE290G, PHE319G, PRO1028H, PRO1038H, PRO1060H, PRO169G, PRO284G, PRO289G, PRO291G, SER1064H, SER1090H, SER172G, SER347G, THR1025H, THR1030H, THR1065H, THR199G, THR200G, THR286G, THR298G, TYR1034H, TYR1059H, TYR1095H, TYR1102H, TYR295G, TYR297G, TYR342G, TYR344G, VAL1049H, VAL1061H, VAL1077H, VAL1106H, VAL343G, VAL349G
• G-I: ALA1442I, ALA390G, ALA406G, ASN1444I, ASN1455I, ASN224G, ASN228G, ASN288G, ASN312G, ASN345G, ASN398G, ASN403G, ASP1451I, ASP330G, ASP401G, GLN1448I, GLN311G, GLU1438I, GLU235G, GLU313G, GLU332G, GLU352G, GLU399G, GLY1433I, GLY1440I, GLY1450I, GLY310G, GLY407G, HIS260G, ILE1449I, ILE226G, ILE287G, ILE351G, ILE397G, LEU1441I, LEU1456I, LEU225G, LEU227G, LEU231G, LEU327G, LEU331G, LEU348G, LEU350G, LEU393G, LEU402G, LEU405G, LEU408G, LYS1432I, LYS1435I, LYS1446I, LYS1447I, LYS1454I, LYS221G, LYS229G, LYS329G, LYS395G, LYS409G, PHE1434I, PHE1452I, PHE1453I, PHE328G, PHE410G, PRO289G, PRO404G, SER230G, SER236G, SER347G, SER394G, SER396G, SER400G, THR1445I, THR286G, THR392G, TRP389G, TYR344G, VAL1436I, VAL1437I, VAL1439I, VAL232G, VAL349G
• G-J: ARG247J, ASN262J, ASN398G, ASN403G, ASP238G, ASP238J, ASP338J, ASP401G, GLN254J, GLN273J, GLU235G, GLU235J, GLU261J, GLU275J, GLU399G, ILE250J, LEU237G, LEU237J, LEU402G, LYS246J, LYS251J, LYS258J, LYS274J, LYS395G, PRO404G, SER236G, SER236J, SER239G, SER239J, SER396G, SER400G, THR240G, THR240J, THR241G, THR241J, TYR234J, TYR276J, VAL232G, VAL243J
• H-I: LYS1454I, SER1064H, THR1065H
• I-J: ARG247J, ASN1444I, ASN248J, ASP1430I, ASP1451I, ASP242J, GLN1448I, GLN254J, GLU1438I, GLY1440I, ILE1449I, ILE244J, ILE250J, LEU1441I, LEU231J, LEU237J, LEU253J, LYS1435I, LYS1447I, LYS246J, LYS251J, PHE1434I, THR1445I, THR241J, TYR234J, VAL1436I, VAL1437I, VAL1439I, VAL243J, VAL245J, VAL249J, VAL339J
• I-K: ALA1035K, ASN967K, ASN969K, ASP1430I, GLU1027K, GLY1020K, GLY1021K, ILE1023K, ILE1024K, ILE1032K, LYS1429I, LYS1432I, PHE1026K, PRO1028K, THR1025K, TYR1000K, TYR970K, VAL1022K
• J-K: ALA1035K, ALA1051K, ALA1109K, ALA1110K, ALA177J, ALA299J, ARG1066K, ARG1079K, ARG1083K, ASN1036K, ASN1048K, ASN1057K, ASN1089K, ASN1107K, ASN170J, ASN171J, ASN180J, ASN198J, ASN288J, ASN341J, ASN345J, ASN346J, ASP1062K, ASP176J, ASP181J, ASP204J, ASP296J, ASP320J, ASP321J, ASP340J, CYS1031K, CYS1055K, CYS1058K, GLN1075K, GLN282J, GLU1027K, GLU1111K, GLU201J, GLU293J, GLY1100K, GLY174J, GLY202J, GLY203J, GLY283J, GLY292J, HIS1074K, HIS1080K, HIS1108K, ILE1003K, ILE1024K, ILE1032K, ILE1033K, ILE1047K, ILE1053K, ILE1069K, ILE205J, ILE287J, ILE325J, LEU1037K, LEU1076K, LEU1084K, LEU175J, LEU294J, LEU331J, LEU348J, LEU350J, LYS1029K, LYS1063K, LYS1067K, LYS1078K, LYS1086K, LYS280J, PHE1005K, PHE1026K, PHE1056K, PHE1092K, PHE1104K, PHE173J, PHE206J, PHE285J, PHE290J, PHE319J, PRO1028K, PRO1038K, PRO1060K, PRO1088K, PRO284J, PRO289J, PRO291J, SER1064K, SER1090K, SER172J, SER347J, THR1025K, THR1030K, THR1065K, THR199J, THR200J, THR286J, THR298J, TYR1034K, TYR1059K, TYR1095K, TYR1102K, TYR295J, TYR297J, TYR342J, TYR344J, VAL1061K, VAL1077K, VAL1106K, VAL343J, VAL349J
• J-L: ALA1442L, ALA390J, ALA406J, ARG353J, ASN1444L, ASN1455L, ASN1457L, ASN224J, ASN228J, ASN288J, ASN312J, ASN345J, ASN398J, ASN403J, ASP1451L, ASP330J, ASP401J, GLN1448L, GLN311J, GLU1438L, GLU235J, GLU313J, GLU332J, GLU352J, GLU399J, GLY1440L, GLY1450L, GLY310J, GLY407J, ILE1449L, ILE226J, ILE287J, ILE351J, ILE397J, LEU1441L, LEU1456L, LEU225J, LEU227J, LEU231J, LEU327J, LEU331J, LEU348J, LEU350J, LEU393J, LEU402J, LEU405J, LEU408J, LYS1435L, LYS1446L, LYS1447L, LYS1454L, LYS221J, LYS229J, LYS329J, LYS395J, LYS409J, PHE1434L, PHE1452L, PHE1453L, PHE290J, PHE328J, PHE410J, PRO289J, PRO291J, PRO404J, SER230J, SER236J, SER347J, SER394J, SER396J, SER400J, THR1445L, THR286J, THR392J, TRP389J, TYR344J, VAL1436L, VAL1437L, VAL1439L, VAL232J, VAL349J
• K-L: LYS1454L, SER1064K, THR1065K