3P7O

rat insulin degrading enzyme (insulysin) e111f mutant with two bound peptides

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 47
  • Norm. En. per Res.: -2.5618
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-22.4253	0.0	-101.213	-123.6383	58	16	0	4841	0	0	0
A-C	-46.617	0.0	-73.7854	-120.4024	47	6	0	3230	0	0	0
B-C	0.0	0.0	-4.6711	-4.6711	6	0	0	226	0	0	0

Interface residues

• A-B: ALA140A, ALA185A, ALA198A, ARG200A, ARG431A, ARG824A, ASN139A, ASN148A, ASN193A, ASN196A, ASP197A, GLN203A, GLN677A, GLU189A, GLU676A, GLY144A, GLY219A, GLY221A, HIS108A, HIS112A, HIS190A, ILE832A, LEU114A, LEU116A, LEU131A, LYS192A, LYS308A, MET113A, PHE111A, PHE115A, PHE141A, PHE202A, PHE820A, SER107A, SER128A, SER137A, SER138A, SER143A, SER96A, THR142A, THR147A, THR220A, THR825A, TRP199A, TYR127A, TYR149A, TYR150A, TYR496A, TYR831A, UNK10B, UNK11B, UNK12B, UNK13B, UNK6B, UNK7B, UNK8B, UNK9B, VAL186A
• A-C: ASN376A, ASN605A, GLN363A, GLU341A, GLU365A, GLU453A, GLU612A, GLY144A, GLY331A, GLY335A, GLY339A, GLY342A, GLY361A, GLY362A, HIS146A, HIS332A, HIS336A, HIS340A, ILE338A, ILE374A, ILE375A, LEU334A, LEU337A, LEU347A, LEU359A, LEU613A, LYS364A, LYS436A, PHE141A, PHE202A, PHE373A, SER143A, SER345A, THR142A, THR358A, TRP199A, TYR333A, TYR609A, UNK1C, UNK2C, UNK3C, UNK4C, UNK5C, UNK6C, UNK7C, VAL360A, VAL377A
• B-C: UNK10B, UNK6C, UNK7B, UNK7C, UNK8B, UNK9B