3P35

polo-like kinase i polo-box domain in complex with mqspspl phosphopeptide

• Total interactions analyzed: 10
• Total true interactions: 7
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 41
  • Norm. En. per Res.: -4.491
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.1049	-20.9777	-46.4637	-79.5463	53	3	0	2354	3	24	23
A-C	0.0	-13.0166	-31.1713	-44.1879	30	1	0	1153	0	11	9
A-D	-49.2977	0.0	-134.833	-184.1307	41	10	2	4201	0	0	0
A-E	0.0	0.0	-52.1274	-52.1274	21	4	1	1830	0	0	0
B-C	-10.6967	-7.9017	-41.3879	-59.9863	36	1	1	1989	0	9	16
B-E	-46.9466	0.0	-125.526	-172.4726	42	11	2	4097	0	0	0
C-E	0.0	0.0	-5.2937	-5.2937	6	0	0	239	0	0	0

Interface residues

• A-B: ARG456A, ARG500A, ARG507A, ARG512A, ARG516B, ARG518B, ARG557B, ARG579B, ASN527A, ASP376A, ASP416B, ASP457A, ASP537B, ASP554B, ASP558B, CYS372A, GLN379A, GLN452A, GLN536B, GLU460A, GLU488B, GLU555B, GLU575B, GLY458A, GLY528A, HIS373A, HIS489B, HIS538B, ILE408A, ILE454A, ILE553B, LEU463A, LEU490B, LEU491B, LEU508A, LEU546A, LYS540B, LYS556B, LYS574B, MET547A, PHE535B, PRO509A, SER375A, SER461A, SER526A, THR459A, THR539B, TRP414B, TYR445A, TYR462A, TYR485B, TYR510A, VAL415B
• A-C: ALA520C, ARG500A, ARG516C, ARG518C, ARG581C, ASN430A, ASN446A, ASP419C, ASP429A, ASP447A, ASP449A, CYS428A, GLY448A, HIS468A, LYS492A, LYS589C, PHE409A, PHE515C, PHE535C, PRO499A, SER418C, SER431A, SER450A, SER466A, SER467A, SER519C, THR517C, TYR445A, TYR462A, TYR582C
• A-D: ALA493A, ALA520A, ARG516A, ARG518A, ASN533A, ASP416A, ASP419A, GLN2D, GLN426A, GLN531A, GLU488A, GLY424A, HIS489A, HIS538A, ILE521A, LEU423A, LEU490A, LEU491A, LEU523A, LEU6D, LYS413A, LYS492A, LYS540A, MET1D, MET486A, PHE482A, PHE535A, PRO5D, SER3D, SER412A, SER418A, SER487A, SER519A, THR517A, TRP414A, TRP514A, TYR417A, TYR425A, TYR485A, VAL411A, VAL415A
• A-E: ARG456A, ARG507A, ASP457A, GLN2E, GLN452A, GLU455A, GLU460A, GLY458A, ILE454A, LEU451A, LEU463A, LEU6E, MET1E, PRO5E, SER3E, SER450A, SER461A, THR459A, TYR445A, TYR453A, TYR462A
• B-C: ALA493B, ALA495B, ARG456C, ARG557B, ARG560B, ARG584C, ASN484B, ASN496B, ASP376C, ASP558B, ASP588C, CYS372C, GLN379C, GLU488B, GLY494B, HIS382C, ILE497B, LEU374C, LEU378C, LEU490B, LEU491B, LEU590C, LEU591C, LYS413B, LYS492B, LYS589C, PHE559B, PRO499B, SER375C, SER412B, SER487B, SER592C, SER593C, THR498B, THR585C, VAL587C
• B-E: ALA493B, ALA520B, ARG516B, ARG518B, ARG557B, ASN533B, ASP416B, ASP419B, GLN2E, GLN426B, GLN531B, GLN536B, GLU488B, GLY424B, HIS489B, HIS538B, ILE521B, LEU423B, LEU490B, LEU491B, LEU523B, LEU6E, LYS413B, LYS492B, LYS540B, MET1E, MET486B, PHE535B, PRO5E, SER3E, SER412B, SER418B, SER487B, SER519B, THR517B, TRP414B, TRP514B, TYR417B, TYR425B, TYR485B, VAL411B, VAL415B
• C-E: LEU591C, LEU6E, LYS589C, PRO5E, SER592C, SER593C