3P1Z

crystal structure of the aperopyrum pernix rna splicing endonuclease

• Total interactions analyzed: 66
• Total true interactions: 24
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 113
  • Norm. En. per Res.: -5.6607
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-131.653	1.2402	-459.657	-590.0698	113	27	23	18408	2	21	22
A-D	-13.4426	-15.324	-210.18	-238.9466	92	7	7	10251	3	27	16
B-C	-13.6405	-8.2585	-207.428	-229.3271	95	9	8	9964	3	28	15
B-D	0.0	22.7824	-101.158	-78.3756	59	5	4	4988	0	18	36
B-F	0.0	1.2457	-0.0158	1.2299	5	0	0	12	0	3	2
B-H	0.0	0.0	-0.2857	-0.2857	8	0	0	58	0	4	7
C-D	-149.6607	-13.8608	-476.139	-639.6606	113	29	25	18648	5	21	22
C-E	0.0	30.3866	-71.1643	-40.7777	55	11	3	3419	0	15	14
C-F	-10.613	-22.1574	-70.2076	-102.978	31	2	1	2655	1	5	6
D-E	-7.1073	-28.9388	-86.3883	-122.4345	33	5	1	2976	1	7	8
D-H	0.0	1.15	-0.0068	1.1431	3	0	0	7	0	4	2
E-F	-127.8096	8.9617	-449.307	-568.1549	116	39	25	18628	2	21	21
E-H	-19.3861	-13.9208	-219.082	-252.3889	98	12	7	10536	3	28	17
F-G	-12.603	-48.9217	-207.481	-269.0057	100	19	7	10423	4	28	18
F-H	0.0	25.8018	-93.8799	-68.0781	60	11	4	4888	0	19	34
G-H	-118.5482	-1.0614	-440.127	-559.7366	111	39	25	18093	6	21	21
G-I	-60.9494	-35.8419	-212.421	-309.2123	108	35	2	9863	7	35	34
G-J	-27.4368	-9.741	-46.0525	-83.2303	27	16	0	1890	0	11	11
G-L	0.0	0.0	-0.2278	-0.2278	5	0	0	68	0	3	1
I-J	-75.8625	24.6583	-437.31	-488.5142	114	35	25	18239	2	21	21
I-L	-13.6735	-18.4206	-217.797	-249.8911	95	12	8	10682	3	28	16
J-K	-15.9656	-21.6337	-203.866	-241.4653	96	11	8	10175	3	28	17
J-L	0.0	30.3017	-103.501	-73.1993	62	9	4	4985	0	20	35
K-L	-91.6584	8.4568	-453.184	-536.3857	115	34	26	18356	4	21	21

Interface residues

• A-B: ALA140B, ALA150A, ALA155B, ALA163A, ALA165A, ALA169B, ARG108B, ARG115A, ARG126B, ARG138A, ARG154A, ARG154B, ARG157B, ARG164A, ARG167A, ARG172B, ARG185B, ARG97A, ASN100B, ASN146B, ASP104B, ASP145B, ASP148B, ASP153A, ASP175B, ASP182B, ASP91A, GLN170A, GLU107B, GLU124A, GLU135A, GLU144B, GLU151B, GLU162A, GLY125A, GLY131A, GLY156B, GLY174B, HIS112A, HIS139B, HIS160B, ILE101B, ILE130A, ILE137B, ILE147B, ILE148A, ILE151A, ILE152B, ILE158A, ILE169A, ILE181B, LEU105B, LEU120A, LEU122A, LEU128A, LEU133A, LEU157A, LEU158B, LEU179B, LEU92A, LYS129A, LYS164B, LYS165B, LYS95A, MET180B, PHE110B, PHE122B, PHE136B, PHE166B, PHE168B, PHE184B, PRO127A, PRO135B, PRO143B, PRO147A, PRO149B, PRO186B, PRO99A, SER123A, SER132A, SER137A, SER142B, SER146A, SER159B, SER168A, SER177B, THR155A, THR159A, THR171B, TRP136A, TRP183B, TYR110A, TYR117A, TYR126A, TYR141B, TYR160A, TYR161A, TYR178B, VAL112B, VAL119A, VAL121A, VAL124B, VAL134A, VAL138B, VAL149A, VAL150B, VAL152A, VAL153B, VAL166A, VAL167B, VAL170B, VAL176B, VAL88A
• A-D: ALA123D, ALA140D, ALA70A, ALA71A, ALA72A, ALA73D, ALA77A, ALA86A, ALA88D, ARG113D, ARG154A, ARG55D, ARG67A, ARG94A, ARG94D, ASN92D, ASP121D, ASP153A, ASP17D, ASP23D, ASP41D, ASP76D, ASP84A, ASP91A, GLN38D, GLU124A, GLU43D, GLU51D, GLU60D, GLU74A, GLY115D, GLY125A, GLY156A, GLY16D, GLY37D, GLY52D, GLY68A, GLY78A, ILE151A, ILE158A, ILE15D, ILE59D, ILE76A, LEU116D, LEU14D, LEU157A, LEU20D, LEU40D, LEU54D, LEU56D, LEU58D, LEU81A, LEU83A, LEU87A, LEU98D, LYS117D, LYS44D, LYS74D, PHE122D, PHE90A, PHE95D, PRO127A, PRO39D, PRO45D, PRO53D, PRO75D, PRO93D, SER114D, SER120D, SER123A, SER18D, SER57A, SER57D, SER82A, THR155A, THR159A, THR22D, THR85A, TRP69A, TYR102D, TYR126A, TYR160A, TYR161A, VAL112D, VAL138D, VAL13D, VAL152A, VAL19D, VAL21D, VAL42D, VAL73A, VAL75A
• B-C: ALA123B, ALA70C, ALA71C, ALA72C, ALA73B, ALA77C, ALA86C, ALA88B, ARG113B, ARG154C, ARG55B, ARG67C, ARG94B, ARG94C, ASN92B, ASP121B, ASP153C, ASP17B, ASP41B, ASP76B, ASP84C, ASP91C, GLN38B, GLU124C, GLU43B, GLU51B, GLU60B, GLU74C, GLY115B, GLY125C, GLY156C, GLY16B, GLY37B, GLY52B, GLY68C, GLY77B, GLY78C, GLY80C, ILE151C, ILE158C, ILE15B, ILE59B, ILE76C, LEU116B, LEU14B, LEU157C, LEU20B, LEU40B, LEU54B, LEU56B, LEU58B, LEU81C, LEU83C, LEU87C, LEU98B, LYS117B, LYS44B, LYS74B, LYS95C, PHE122B, PHE90C, PHE95B, PRO127C, PRO39B, PRO45B, PRO53B, PRO75B, PRO93B, SER114B, SER120B, SER123C, SER18B, SER57B, SER57C, SER82C, THR155C, THR159C, THR22B, THR85C, TRP69C, TYR102B, TYR126C, TYR161C, TYR99B, VAL112B, VAL138B, VAL13B, VAL152C, VAL19B, VAL21B, VAL24B, VAL42B, VAL73C, VAL75C, VAL88C
• B-D: ALA140B, ALA155B, ALA155D, ARG154B, ARG154D, ARG157B, ARG157D, ARG94B, ARG94D, ASN92B, ASN92D, ASP121B, ASP121D, ASP148B, ASP148D, GLU151B, GLU151D, GLU43B, GLU43D, GLY115B, GLY115D, GLY119B, GLY119D, HIS139B, HIS139D, HIS160B, HIS160D, ILE152B, LEU116B, LEU116D, LEU158B, LEU158D, LEU98B, LEU98D, LYS117B, LYS117D, LYS44B, PHE118B, PHE118D, PHE95B, PHE95D, PRO149B, PRO149D, SER114B, SER114D, SER120B, SER120D, SER159D, SER161B, SER161D, TRP183B, TRP183D, TYR141B, TYR141D, VAL150B, VAL150D, VAL153B, VAL153D, VAL162D
• B-F: ASN146F, ASP76B, GLU144F, LYS74B, PRO75B
• B-H: ARG90B, ARG90H, GLY91B, GLY91H, PRO93B, PRO93H, THR87B, THR87H
• C-D: ALA140D, ALA150C, ALA155D, ALA163C, ALA165C, ALA169D, ARG103D, ARG108D, ARG115C, ARG126D, ARG138C, ARG154C, ARG154D, ARG157D, ARG164C, ARG167C, ARG172D, ARG185D, ARG93C, ARG97C, ASN100D, ASN146D, ASP104D, ASP145D, ASP148D, ASP153C, ASP175D, ASP182D, ASP91C, GLN170C, GLU107D, GLU124C, GLU135C, GLU144D, GLU151D, GLU162C, GLY125C, GLY131C, GLY156D, GLY174D, GLY96C, HIS112C, HIS139D, HIS160D, ILE101D, ILE130C, ILE137D, ILE147D, ILE148C, ILE151C, ILE152D, ILE158C, ILE169C, ILE181D, LEU105D, LEU120C, LEU122C, LEU128C, LEU133C, LEU157C, LEU179D, LEU92C, LYS129C, LYS164D, LYS165D, LYS95C, MET180D, PHE110D, PHE136D, PHE166D, PHE168D, PHE184D, PRO127C, PRO135D, PRO143D, PRO147C, PRO149D, PRO186D, PRO99C, SER123C, SER132C, SER137C, SER142D, SER146C, SER159D, SER168C, SER177D, THR155C, THR159C, THR171D, TRP136C, TRP183D, TYR110C, TYR117C, TYR126C, TYR141D, TYR160C, TYR161C, TYR178D, VAL119C, VAL121C, VAL124D, VAL134C, VAL138D, VAL149C, VAL150D, VAL152C, VAL153D, VAL166C, VAL167D, VAL170D, VAL176D, VAL88C
• C-E: ALA165C, ALA165E, ALA77C, ALA77E, ARG104C, ARG104E, ARG105C, ARG105E, ARG138C, ARG138E, ARG46C, ARG46E, ASP143C, GLU135C, GLU135E, GLU20C, GLU20E, GLY102E, GLY106C, GLY106E, GLY131C, GLY131E, GLY139C, GLY139E, GLY18C, GLY21C, GLY21E, GLY78C, GLY78E, GLY80C, GLY80E, ILE130C, ILE130E, ILE76C, ILE76E, LEU79C, LEU79E, LEU81C, LEU81E, LYS129C, LYS129E, PHE23C, PRO49C, PRO49E, SER132C, SER132E, TRP136C, TRP136E, VAL103C, VAL103E, VAL134C, VAL134E, VAL19C, VAL19E, VAL75E
• C-F: ALA169F, ALA77C, ARG16C, ARG172F, ASP145F, ASP175F, GLU144F, GLU20C, GLU74C, GLY173F, GLY174F, GLY18C, GLY21C, GLY78C, GLY80C, ILE76C, LEU17C, LEU79C, LEU81C, PHE23C, PRO143F, SER142F, SER177F, THR171F, TYR141F, TYR178F, VAL170F, VAL176F, VAL19C, VAL22C, VAL75C
• D-E: ALA169D, ALA77E, ARG16E, ARG172D, ASP175D, GLU144D, GLU20E, GLU74E, GLU83D, GLY173D, GLY174D, GLY18E, GLY21E, GLY78E, GLY80E, ILE76E, LEU17E, LEU79E, LEU81E, LYS3E, MET63E, PHE23E, PRO143D, SER142D, SER177D, THR171D, TYR141D, TYR178D, VAL170D, VAL176D, VAL19E, VAL22E, VAL75E
• D-H: ASP76H, GLU144D, PRO75H
• E-F: ALA140F, ALA150E, ALA155F, ALA163E, ALA165E, ALA169F, ARG108F, ARG115E, ARG126F, ARG138E, ARG154E, ARG154F, ARG157F, ARG164E, ARG167E, ARG172F, ARG185F, ARG93E, ARG97E, ASN100F, ASN146F, ASP104F, ASP145F, ASP148F, ASP153E, ASP175F, ASP182F, ASP91E, GLN170E, GLU107F, GLU124E, GLU135E, GLU144F, GLU151F, GLU162E, GLY125E, GLY131E, GLY156F, GLY174F, GLY96E, HIS112E, HIS139F, HIS160F, ILE101F, ILE130E, ILE137F, ILE147F, ILE148E, ILE151E, ILE152F, ILE158E, ILE169E, ILE181F, LEU105F, LEU120E, LEU122E, LEU128E, LEU133E, LEU157E, LEU158F, LEU179F, LEU92E, LYS129E, LYS164F, LYS165F, LYS95E, MET180F, PHE110F, PHE122F, PHE136F, PHE166F, PHE168F, PHE184F, PRO127E, PRO143F, PRO147E, PRO149F, PRO186F, PRO99E, SER123E, SER132E, SER137E, SER141E, SER142F, SER146E, SER159F, SER168E, SER177F, THR155E, THR159E, THR171F, TRP136E, TRP183F, TYR110E, TYR117E, TYR125F, TYR126E, TYR141F, TYR160E, TYR161E, TYR178F, VAL112F, VAL119E, VAL121E, VAL124F, VAL134E, VAL138F, VAL149E, VAL150F, VAL152E, VAL153F, VAL166E, VAL167F, VAL170F, VAL176F, VAL88E
• E-H: ALA123H, ALA140H, ALA70E, ALA71E, ALA72E, ALA73H, ALA77E, ALA86E, ALA88H, ARG113H, ARG154E, ARG55H, ARG67E, ARG94E, ARG94H, ASN92H, ASP121H, ASP153E, ASP17H, ASP23H, ASP41H, ASP76H, ASP84E, ASP91E, GLN38H, GLU124E, GLU43H, GLU51H, GLU60H, GLU74E, GLY115H, GLY125E, GLY156E, GLY16H, GLY37H, GLY52H, GLY68E, GLY77H, GLY78E, GLY80E, ILE101H, ILE151E, ILE158E, ILE15H, ILE59H, ILE76E, LEU105H, LEU116H, LEU14H, LEU157E, LEU20H, LEU40H, LEU54H, LEU56H, LEU58H, LEU81E, LEU83E, LEU87E, LEU98H, LYS117H, LYS44H, LYS74H, PHE122H, PHE90E, PHE95H, PRO127E, PRO39H, PRO45H, PRO53H, PRO75H, PRO93H, SER114H, SER120H, SER123E, SER18H, SER57E, SER57H, SER82E, THR155E, THR159E, THR22H, THR85E, TRP69E, TYR102H, TYR126E, TYR160E, TYR161E, TYR99H, VAL112H, VAL138H, VAL13H, VAL152E, VAL19H, VAL21H, VAL42H, VAL73E, VAL75E, VAL88E
• F-G: ALA123F, ALA140F, ALA70G, ALA71G, ALA72G, ALA73F, ALA77G, ALA86G, ALA88F, ARG113F, ARG154G, ARG55F, ARG67G, ARG94F, ARG94G, ASN92F, ASP121F, ASP153G, ASP17F, ASP41F, ASP76F, ASP84G, ASP91G, GLN38F, GLU124G, GLU43F, GLU51F, GLU60F, GLU74G, GLY115F, GLY125G, GLY156G, GLY16F, GLY37F, GLY52F, GLY68G, GLY78G, GLY80G, GLY91F, ILE101F, ILE151G, ILE158G, ILE15F, ILE59F, ILE76G, LEU105F, LEU116F, LEU14F, LEU157G, LEU20F, LEU40F, LEU54F, LEU56F, LEU58F, LEU79G, LEU81G, LEU83G, LEU87G, LEU98F, LYS117F, LYS44F, LYS74F, LYS95G, PHE122F, PHE90G, PHE95F, PRO127G, PRO39F, PRO45F, PRO53F, PRO75F, PRO93F, SER114F, SER120F, SER123G, SER18F, SER57F, SER57G, SER82G, THR155G, THR159G, THR22F, THR85G, TRP69G, TYR102F, TYR126G, TYR161G, TYR99F, VAL112F, VAL124F, VAL138F, VAL13F, VAL152G, VAL19F, VAL21F, VAL24F, VAL42F, VAL73G, VAL75G, VAL88G
• F-H: ALA155F, ALA155H, ARG154F, ARG154H, ARG157F, ARG157H, ARG94F, ARG94H, ASN92F, ASN92H, ASP121F, ASP121H, ASP148F, ASP148H, GLU151F, GLU151H, GLU43F, GLU43H, GLY115F, GLY115H, GLY119F, GLY119H, GLY156H, HIS139F, HIS139H, HIS160F, HIS160H, ILE152F, ILE152H, LEU116F, LEU116H, LEU158F, LEU158H, LEU98F, LEU98H, LYS117F, LYS117H, PHE118F, PHE118H, PHE95F, PHE95H, PRO149F, PRO149H, SER114F, SER114H, SER120F, SER120H, SER159F, SER159H, SER161F, SER161H, TRP183F, TRP183H, TYR141F, TYR141H, VAL150F, VAL150H, VAL153F, VAL153H, VAL162H
• G-H: ALA140H, ALA150G, ALA155H, ALA163G, ALA165G, ALA169H, ARG103H, ARG108H, ARG115G, ARG126H, ARG138G, ARG154G, ARG154H, ARG157H, ARG164G, ARG167G, ARG172H, ARG185H, ARG97G, ASN100H, ASN146H, ASP104H, ASP145H, ASP148H, ASP153G, ASP175H, ASP182H, ASP91G, GLN170G, GLU107H, GLU118G, GLU124G, GLU135G, GLU144H, GLU151H, GLU162G, GLY125G, GLY131G, GLY156H, GLY174H, GLY96G, HIS112G, HIS139H, HIS160H, ILE101H, ILE130G, ILE137H, ILE147H, ILE148G, ILE151G, ILE152H, ILE158G, ILE169G, ILE181H, LEU105H, LEU120G, LEU122G, LEU128G, LEU133G, LEU157G, LEU179H, LEU92G, LYS129G, LYS164H, LYS165H, LYS95G, MET180H, PHE110H, PHE136H, PHE166H, PHE168H, PHE184H, PRO127G, PRO143H, PRO147G, PRO149H, PRO186H, SER123G, SER132G, SER137G, SER142H, SER146G, SER159H, SER168G, SER177H, THR155G, THR159G, THR171H, TRP136G, TRP183H, TYR110G, TYR117G, TYR126G, TYR141H, TYR160G, TYR161G, TYR178H, VAL119G, VAL121G, VAL124H, VAL134G, VAL138H, VAL149G, VAL150H, VAL152G, VAL153H, VAL166G, VAL167H, VAL170H, VAL176H, VAL88G
• G-I: ALA140G, ALA140I, ALA14G, ALA15G, ALA77I, ARG104G, ARG104I, ARG105G, ARG105I, ARG138G, ARG138I, ARG167I, ARG16G, ARG16I, ARG43G, ARG43I, ARG46G, ARG46I, ASN144G, ASP143G, ASP143I, CYS27G, GLU118G, GLU118I, GLU135G, GLU135I, GLU20G, GLU20I, GLU25G, GLU26G, GLU48G, GLU48I, GLU51I, GLY102G, GLY102I, GLY106G, GLY106I, GLY131I, GLY139G, GLY139I, GLY18G, GLY18I, GLY21G, GLY21I, GLY40I, GLY45G, GLY78I, GLY80G, GLY80I, HIS145G, HIS145I, ILE130I, ILE76I, LEU100G, LEU100I, LEU108I, LEU120I, LEU128I, LEU133I, LEU17G, LEU17I, LEU42G, LEU42I, LEU47G, LEU47I, LEU50I, LEU79G, LEU79I, LEU81G, LEU81I, LEU83I, LYS129G, LYS129I, LYS44G, MET142G, MET142I, MET63G, PHE23G, PHE23I, PRO49G, PRO49I, SER132G, SER132I, SER137G, SER137I, SER141G, SER82I, THR107G, THR107I, THR85I, TRP136G, TRP136I, TYR126I, TYR41I, TYR89I, VAL101G, VAL101I, VAL103G, VAL103I, VAL109G, VAL116G, VAL134I, VAL19G, VAL19I, VAL22G, VAL22I, VAL24G, VAL75I
• G-J: ALA140G, ALA165G, ARG103J, ARG108J, ARG138G, ARG167G, ARG172J, ASN144G, ASP143G, ASP175J, GLU135G, GLU144J, GLY139G, GLY173J, GLY174J, HIS145G, MET142G, PRO143J, SER141G, SER142J, SER177J, THR171J, TYR141J, VAL134G, VAL166G, VAL170J, VAL176J
• G-L: ARG43G, GLY16L, ILE15L, LYS44G, PRO75L
• I-J: ALA140J, ALA150I, ALA155J, ALA163I, ALA165I, ALA169J, ARG108J, ARG115I, ARG126J, ARG138I, ARG154I, ARG154J, ARG157J, ARG164I, ARG167I, ARG172J, ARG185J, ARG97I, ASN100J, ASN146J, ASP104J, ASP145J, ASP148J, ASP153I, ASP175J, ASP182J, ASP91I, GLN170I, GLU107J, GLU118I, GLU124I, GLU135I, GLU144J, GLU151J, GLU162I, GLY125I, GLY131I, GLY156J, GLY174J, GLY96I, HIS112I, HIS139J, HIS160J, ILE101J, ILE130I, ILE137J, ILE147J, ILE148I, ILE151I, ILE152J, ILE158I, ILE169I, ILE181J, LEU105J, LEU120I, LEU122I, LEU128I, LEU133I, LEU157I, LEU158J, LEU179J, LEU92I, LYS129I, LYS164J, LYS165J, LYS95I, MET180J, PHE110J, PHE122J, PHE136J, PHE166J, PHE168J, PHE184J, PRO127I, PRO135J, PRO143J, PRO147I, PRO149J, PRO186J, SER123I, SER132I, SER137I, SER142J, SER146I, SER159J, SER168I, SER177J, THR155I, THR159I, THR171J, TRP136I, TRP183J, TYR110I, TYR117I, TYR126I, TYR141J, TYR160I, TYR161I, TYR178J, VAL112J, VAL119I, VAL121I, VAL124J, VAL134I, VAL138J, VAL149I, VAL150J, VAL152I, VAL153J, VAL166I, VAL167J, VAL170J, VAL176J, VAL88I
• I-L: ALA123L, ALA140L, ALA70I, ALA71I, ALA72I, ALA73L, ALA77I, ALA86I, ALA88L, ARG113L, ARG154I, ARG55L, ARG67I, ARG94I, ARG94L, ASN92L, ASP121L, ASP153I, ASP17L, ASP23L, ASP41L, ASP76L, ASP84I, ASP91I, GLN38L, GLU124I, GLU43L, GLU51L, GLU60L, GLU74I, GLY115L, GLY125I, GLY156I, GLY16L, GLY37L, GLY52L, GLY68I, GLY78I, ILE151I, ILE158I, ILE15L, ILE59L, ILE76I, LEU105L, LEU116L, LEU14L, LEU157I, LEU20L, LEU40L, LEU54L, LEU56L, LEU58L, LEU81I, LEU83I, LEU87I, LEU98L, LYS117L, LYS44L, LYS74L, PHE122L, PHE90I, PHE95L, PRO127I, PRO39L, PRO45L, PRO53L, PRO75L, PRO93L, SER114L, SER120L, SER123I, SER18L, SER57I, SER57L, SER82I, THR155I, THR159I, THR22L, THR85I, TRP69I, TYR102L, TYR126I, TYR160I, TYR161I, VAL112L, VAL124L, VAL138L, VAL13L, VAL152I, VAL19L, VAL21L, VAL42L, VAL73I, VAL75I, VAL88I
• J-K: ALA123J, ALA140J, ALA70K, ALA71K, ALA72K, ALA73J, ALA77K, ALA86K, ALA88J, ARG113J, ARG154K, ARG55J, ARG67K, ARG94J, ARG94K, ASN92J, ASP121J, ASP153K, ASP17J, ASP23J, ASP41J, ASP76J, ASP84K, ASP91K, GLN38J, GLU124K, GLU43J, GLU51J, GLU60J, GLU74K, GLY115J, GLY125K, GLY156K, GLY16J, GLY37J, GLY52J, GLY68K, GLY78K, GLY80K, ILE151K, ILE158K, ILE15J, ILE59J, ILE76K, LEU116J, LEU14J, LEU157K, LEU20J, LEU40J, LEU54J, LEU56J, LEU58J, LEU79K, LEU81K, LEU83K, LEU87K, LEU98J, LYS117J, LYS44J, LYS74J, LYS95K, PHE122J, PHE90K, PHE95J, PRO127K, PRO39J, PRO45J, PRO53J, PRO75J, PRO93J, SER114J, SER120J, SER123K, SER18J, SER57J, SER57K, SER82K, THR155K, THR159K, THR22J, THR85K, TRP69K, TYR102J, TYR126K, TYR161K, TYR99J, VAL112J, VAL138J, VAL13J, VAL152K, VAL19J, VAL21J, VAL42J, VAL73K, VAL75K, VAL88K
• J-L: ALA155J, ALA155L, ARG154J, ARG154L, ARG157J, ARG157L, ARG94J, ARG94L, ASN92J, ASN92L, ASP121J, ASP121L, ASP148J, ASP148L, GLU151J, GLU151L, GLU43J, GLU43L, GLY115J, GLY115L, GLY119J, GLY119L, HIS139J, HIS139L, HIS160J, HIS160L, ILE147J, ILE147L, ILE152J, ILE152L, LEU116J, LEU116L, LEU158J, LEU158L, LEU98J, LEU98L, LYS117J, LYS117L, LYS44J, PHE118J, PHE118L, PHE95J, PHE95L, PRO149J, PRO149L, SER114J, SER114L, SER120J, SER120L, SER159J, SER159L, SER161J, SER161L, TRP183J, TRP183L, TYR141J, TYR141L, VAL150J, VAL150L, VAL153J, VAL153L, VAL162L
• K-L: ALA140L, ALA150K, ALA155L, ALA163K, ALA165K, ALA169L, ARG108L, ARG115K, ARG126L, ARG138K, ARG154K, ARG154L, ARG157L, ARG164K, ARG167K, ARG172L, ARG185L, ARG97K, ASN100L, ASN146L, ASP104L, ASP145L, ASP148L, ASP153K, ASP175L, ASP182L, ASP91K, GLN170K, GLU107L, GLU118K, GLU124K, GLU135K, GLU144L, GLU151L, GLU162K, GLY125K, GLY131K, GLY156L, GLY174L, GLY96K, HIS112K, HIS139L, HIS160L, ILE101L, ILE130K, ILE137L, ILE147L, ILE148K, ILE151K, ILE152L, ILE158K, ILE169K, ILE181L, LEU105L, LEU120K, LEU122K, LEU128K, LEU133K, LEU157K, LEU158L, LEU179L, LEU92K, LYS129K, LYS164L, LYS165L, LYS95K, MET180L, PHE110L, PHE136L, PHE166L, PHE168L, PHE184L, PRO127K, PRO135L, PRO143L, PRO147K, PRO149L, PRO186L, PRO99K, SER123K, SER132K, SER137K, SER141K, SER142L, SER146K, SER159L, SER168K, SER177L, THR155K, THR159K, THR171L, TRP136K, TRP183L, TYR110K, TYR117K, TYR125L, TYR126K, TYR141L, TYR160K, TYR161K, TYR178L, VAL119K, VAL121K, VAL124L, VAL134K, VAL138L, VAL149K, VAL150L, VAL152K, VAL153L, VAL166K, VAL167L, VAL170L, VAL176L, VAL88K