3P16

crystal structure of dna polymerase iii sliding clamp

• Total interactions analyzed: 15
• Total true interactions: 11
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 117
  • Norm. En. per Res.: -4.0305
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-97.1073	-57.3706	-317.087	-471.5649	117	28	14	12788	8	36	22
A-C	-13.1408	-65.3856	-178.843	-257.3694	98	13	5	9125	3	35	26
A-E	0.0	0.0	-0.1457	-0.1457	8	0	0	46	0	3	4
B-C	-10.5062	-39.1682	-46.5367	-96.2111	36	3	1	1952	3	21	18
B-D	0.0	5.0942	-123.055	-117.9608	79	7	1	6083	0	14	20
B-F	0.0	0.0	-0.0698	-0.0698	6	0	0	12	0	4	1
C-D	-61.0071	-77.7798	-292.867	-431.6539	114	14	13	12027	7	37	21
C-E	0.0	-10.9282	-66.3496	-77.2778	50	2	0	3061	0	11	11
D-E	0.0	-17.3361	-26.4958	-43.8319	15	2	0	1066	0	13	13
D-F	-13.6245	-8.7509	-196.177	-218.5524	86	18	4	8629	1	28	21
E-F	-85.5525	-36.7487	-258.822	-381.1232	114	15	15	11598	2	38	24

Interface residues

• A-B: ALA108A, ALA108B, ALA114A, ALA114B, ALA283A, ALA283B, ALA288A, ALA288B, ALA291A, ALA291B, ALA310A, ALA310B, ALA312A, ALA312B, ALA318A, ALA318B, ALA35B, ALA92A, ALA92B, ARG106A, ARG106B, ARG115A, ARG115B, ARG19A, ARG19B, ARG293A, ARG307A, ARG307B, ARG317A, ARG317B, ARG36B, ARG84A, ARG84B, ARG91A, ARG91B, ASN105A, ASN113A, ASN113B, ASN95A, ASN95B, ASP313B, ASP314A, ASP314B, ASP321A, ASP321B, ASP88A, ASP88B, CYS111A, CYS111B, GLU279A, GLU282A, GLU282B, GLU319A, GLU319B, GLU320A, GLU320B, GLY112A, GLY112B, GLY311A, GLY311B, GLY316A, GLY316B, ILE284B, ILE89A, ILE89B, LEU109A, LEU109B, LEU118A, LEU118B, LEU286A, LEU286B, LEU289A, LEU289B, LEU308A, LEU308B, LEU322A, LEU322B, LEU85A, LEU85B, LEU86A, LEU86B, LEU93A, LEU93B, LYS285A, LYS285B, LYS96A, MET121B, PHE116A, PHE116B, PRO119A, PRO119B, PRO94A, PRO94B, SER117A, SER117B, SER309A, SER309B, SER82A, SER82B, SER87A, SER87B, THR110A, THR120A, THR120B, THR90A, THR90B, VAL107A, VAL107B, VAL287A, VAL287B, VAL290A, VAL290B, VAL315A, VAL315B, VAL323A, VAL323B, VAL81B
• A-C: ALA154A, ALA154C, ALA155A, ALA180C, ALA187C, ALA256A, ALA256C, ALA271C, ALA295A, ALA295C, ALA359C, ALA35A, ALA363C, ALA38A, ARG157A, ARG183A, ARG183C, ARG185A, ARG185C, ARG262C, ARG293A, ARG293C, ARG36A, ARG36C, ARG399A, ARG399C, ARG84A, ASN336A, ASP158A, ASP158C, ASP159A, ASP159C, ASP182A, ASP182C, ASP255A, ASP255C, ASP292C, GLN263C, GLN296A, GLU257A, GLU257C, GLU268C, GLU329C, GLY156A, GLY294A, GLY360C, HIS269C, LEU161A, LEU161C, LEU164A, LEU164C, LEU186C, LEU205C, LEU253A, LEU254A, LEU264C, LEU265C, LEU331C, LEU394C, LEU395C, LEU400A, LYS209A, LYS260A, LYS260C, LYS361C, MET163A, MET163C, MET396A, MET396C, PHE184A, PHE184C, PHE258A, PHE258C, PHE261C, PHE356C, PRO162A, PRO162C, PRO259A, PRO259C, PRO266C, PRO34A, PRO362C, PRO37A, PRO397A, PRO397C, PRO40A, THR160A, THR160C, THR165A, THR181C, THR270C, THR357C, THR358C, TYR339A, TYR61A, VAL398A, VAL398C, VAL39A
• A-E: ARG298A, ASN105E, GLU300A, GLY104E, LEU13E, LEU400A, PRO330A, THR332A
• B-C: ALA291C, ALA295C, ALA312C, ALA35B, ALA38B, ARG293B, ARG293C, ARG307C, ARG317C, ARG36B, ARG84B, ASN32B, ASP158B, ASP159B, ASP292C, ASP303C, ASP313C, ASP314C, ASP60B, GLU319C, GLU62B, GLY294C, GLY316C, LEU33B, LEU42B, LYS209B, LYS31B, PRO330C, PRO34B, PRO37B, THR160B, THR210B, TYR61B, VAL290C, VAL315C, VAL39B
• B-D: ALA108D, ALA256B, ALA35D, ALA38B, ALA38D, ARG106D, ARG115D, ARG252B, ARG36B, ARG36D, ARG84D, ASN105D, ASP125B, ASP125D, ASP158B, ASP159B, ASP255B, ASP60B, GLU103D, GLU124B, GLU124D, GLU257B, GLU62B, GLY104D, GLY238B, GLY44D, GLY83D, HIS101D, LEU118D, LEU161B, LEU205B, LEU239B, LEU253B, LEU254B, LEU42B, LEU42D, LEU80B, LEU80D, LEU85D, LEU86D, LYS209B, MET121B, MET121D, MET163B, PHE116D, PHE59B, PRO119D, PRO122B, PRO122D, PRO127B, PRO130B, PRO162B, PRO207B, PRO37B, PRO37D, PRO40B, PRO40D, SER117D, SER43B, SER43D, SER82D, THR110D, THR120D, THR128B, THR160B, THR165B, THR210B, TYR126B, TYR61B, TYR61D, VAL102D, VAL123B, VAL123D, VAL206B, VAL39B, VAL39D, VAL41B, VAL41D, VAL81D
• B-F: ASN105B, GLU103B, GLU300F, GLY104B, LEU400F, THR332F
• C-D: ALA108C, ALA114C, ALA114D, ALA283C, ALA283D, ALA288C, ALA288D, ALA291C, ALA291D, ALA310C, ALA310D, ALA312C, ALA312D, ALA318C, ALA318D, ALA92C, ALA92D, ARG106C, ARG106D, ARG115C, ARG115D, ARG19C, ARG293C, ARG307C, ARG307D, ARG317C, ARG317D, ARG36D, ARG84C, ARG84D, ARG91C, ARG91D, ASN105D, ASN113C, ASN113D, ASN95C, ASN95D, ASP313D, ASP314C, ASP314D, ASP321C, ASP321D, ASP88C, ASP88D, CYS111C, CYS111D, GLU279C, GLU279D, GLU282C, GLU282D, GLU319C, GLU319D, GLU320C, GLU320D, GLY112C, GLY112D, GLY311C, GLY311D, GLY316C, GLY316D, ILE284D, ILE89C, ILE89D, LEU109C, LEU109D, LEU118C, LEU118D, LEU286C, LEU286D, LEU289C, LEU289D, LEU308C, LEU308D, LEU322C, LEU322D, LEU85C, LEU85D, LEU86C, LEU86D, LEU93C, LEU93D, LYS285C, LYS285D, LYS96C, LYS96D, PHE116C, PHE116D, PRO119C, PRO119D, PRO94C, PRO94D, SER117C, SER117D, SER305D, SER309C, SER309D, SER82C, SER87C, SER87D, THR110C, THR110D, THR120D, THR90C, THR90D, VAL107C, VAL287C, VAL287D, VAL290C, VAL290D, VAL306D, VAL315C, VAL315D, VAL323C, VAL323D
• C-E: ALA108C, ALA256E, ALA35C, ALA38C, ALA38E, ARG106C, ARG252E, ARG36C, ARG84C, ASN105C, ASP125C, ASP125E, ASP158E, ASP159E, ASP255E, ASP60E, GLU103C, GLU124C, GLU62E, GLY104C, LEU118C, LEU161E, LEU254E, LEU42E, LEU85C, MET121C, MET163E, PRO119C, PRO122C, PRO127E, PRO162E, PRO34C, PRO37C, PRO37E, PRO40C, PRO40E, SER117C, SER43C, SER82C, THR120C, THR160E, THR165E, TYR126E, TYR61E, VAL102C, VAL107C, VAL39C, VAL39E, VAL41C, VAL41E
• D-E: ALA312D, ALA35E, ALA38E, ARG293D, ARG317D, ARG36E, ASP159E, ASP292D, ASP313D, ASP314D, PRO34E, PRO37E, TYR61E, VAL315D, VAL39E
• D-F: ALA154D, ALA180D, ALA187D, ALA256D, ALA256F, ALA271D, ALA295D, ALA359D, ALA35F, ALA363D, ALA38F, ARG157F, ARG183D, ARG183F, ARG185D, ARG185F, ARG293D, ARG293F, ARG36F, ARG399D, ARG399F, ASP158F, ASP159D, ASP159F, ASP182D, ASP182F, ASP255F, GLN263D, GLN263F, GLU257D, GLU257F, GLU329D, GLU62F, GLY156F, GLY328D, GLY360D, GLY360F, HIS269D, LEU161D, LEU161F, LEU164D, LEU164F, LEU186D, LEU205F, LEU254F, LEU264D, LEU265D, LEU331D, LEU394D, LEU395D, LYS260D, LYS260F, LYS361D, MET163D, MET163F, MET396D, MET396F, PHE184D, PHE184F, PHE258D, PHE258F, PHE261D, PHE356D, PRO162D, PRO162F, PRO259D, PRO259F, PRO266D, PRO330D, PRO34F, PRO362D, PRO37F, PRO397D, PRO397F, THR160D, THR160F, THR165F, THR181D, THR270D, THR357D, THR358D, TYR339D, TYR339F, TYR393D, VAL398D, VAL398F
• E-F: ALA108E, ALA108F, ALA114E, ALA114F, ALA283E, ALA283F, ALA288E, ALA288F, ALA291E, ALA291F, ALA310E, ALA310F, ALA312E, ALA312F, ALA318E, ALA318F, ALA92E, ALA92F, ARG106E, ARG106F, ARG115E, ARG115F, ARG19F, ARG293F, ARG307E, ARG307F, ARG317E, ARG317F, ARG36E, ARG84E, ARG91E, ARG91F, ASN105E, ASN105F, ASN113E, ASN113F, ASN95F, ASP292F, ASP313E, ASP313F, ASP314E, ASP314F, ASP321E, ASP321F, ASP88E, ASP88F, CYS111E, CYS111F, GLU279E, GLU279F, GLU282E, GLU282F, GLU319E, GLU319F, GLU320E, GLU320F, GLY112E, GLY112F, GLY311E, GLY311F, GLY316E, GLY316F, ILE89E, ILE89F, LEU109E, LEU109F, LEU118E, LEU118F, LEU286E, LEU286F, LEU289E, LEU289F, LEU308E, LEU308F, LEU322E, LEU322F, LEU85E, LEU85F, LEU86F, LEU93E, LEU93F, LYS285E, LYS285F, MET121E, MET121F, PHE116E, PHE116F, PRO119E, PRO119F, PRO94E, PRO94F, SER117E, SER117F, SER309E, SER309F, SER82E, SER82F, SER87E, SER87F, THR110E, THR110F, THR120E, THR120F, THR90E, THR90F, VAL107E, VAL107F, VAL287E, VAL287F, VAL290E, VAL290F, VAL315E, VAL315F, VAL323E