3P0Y

anti-egfr/her3 fab dl11 in complex with domain iii of egfr extracellular region

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-H
  • Int. Res.: 71
  • Norm. En. per Res.: -5.1563
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-H	-70.5399	-72.4186	-223.14	-366.0985	71	8	3	7789	9	22	15
A-L	-5.097	-10.2236	-8.0429	-23.3635	27	0	0	723	0	12	6
H-L	-72.422	17.1051	-469.203	-524.5199	192	12	14	18240	2	19	28

Interface residues

• A-H: ALA100H, ALA415A, ALA52H, ALA53H, ARG94H, ARG97H, ASN449A, ASN452A, ASN473A, ASP32H, ASP434A, ASP436A, ASP58H, ASP61H, GLN384A, GLN408A, GLN411A, GLN462A, GLU100H, GLU50H, GLU95H, GLY31H, GLY410A, GLY435A, GLY441A, GLY461A, GLY54H, GLY55H, HIS35H, HIS409A, ILE34H, ILE438A, ILE439A, ILE451A, ILE466A, ILE467A, ILE51H, LEU29H, LEU382A, LEU456A, LYS407A, LYS454A, LYS455A, LYS463A, LYS465A, LYS64H, MET100H, PHE100H, PHE412A, PHE457A, SER30H, SER418A, SER440A, SER460A, SER468A, SER52H, SER96H, SER99H, THR459A, THR464A, THR57H, THR73H, TRP33H, TRP453A, TRP47H, TYR56H, TYR59H, VAL416A, VAL417A, VAL437A, VAL98H
• A-L: ALA30L, ASN449A, ASN452A, ASN473A, ASP1L, ASP32L, GLN27L, GLU472A, GLU92L, GLU94L, ILE451A, ILE466A, ILE467A, LYS454A, LYS463A, LYS465A, PHE53L, PRO93L, SER460A, SER468A, SER50L, SER91L, THR31L, THR464A, TRP453A, TYR49L, TYR96L
• H-L: ALA100H, ALA125H, ALA130L, ALA136H, ALA137H, ALA168H, ALA34L, ALA43L, ALA51L, ALA60H, ALA93H, ARG142L, ARG38H, ARG94H, ARG97H, ASN137L, ASN138L, ASN158L, ASP101H, ASP122L, ASP144H, ASP167L, ASP170L, ASP1L, ASP32L, ASP58H, ASP61H, CYS134L, CYS140H, CYS88L, CYS92H, GLN100L, GLN105H, GLN124L, GLN160L, GLN166L, GLN171H, GLN37L, GLN38L, GLN39H, GLN6L, GLN89L, GLN90L, GLU100H, GLU123L, GLU161L, GLU165L, GLU213L, GLU46H, GLU50H, GLU6H, GLU92L, GLU94L, GLU95H, GLY101L, GLY104H, GLY106H, GLY139H, GLY157L, GLY162H, GLY174H, GLY212L, GLY41L, GLY42H, GLY44H, GLY49H, GLY99L, HIS164H, HIS35H, ILE117L, ILE48L, LEU124H, LEU125L, LEU135L, LEU136L, LEU138H, LEU141H, LEU170H, LEU175H, LEU175L, LEU178H, LEU179L, LEU181L, LEU45H, LEU46L, LEU47L, LEU48H, LEU54L, LYS103L, LYS126L, LYS143H, LYS169L, LYS207L, LYS209H, LYS214H, LYS39L, LYS42L, LYS43H, LYS45L, LYS64H, MET100H, PHE100H, PHE116L, PHE118L, PHE122H, PHE139L, PHE166H, PHE209L, PHE53L, PHE98L, PRO119L, PRO120L, PRO123H, PRO126H, PRO167H, PRO40L, PRO44L, PRO93L, PRO95L, SER114L, SER120H, SER121L, SER127H, SER127L, SER128H, SER131L, SER159L, SER161H, SER162L, SER168L, SER172H, SER173H, SER174L, SER176L, SER177H, SER177L, SER179H, SER180H, SER208L, SER215H, SER50L, SER52L, SER56L, SER62H, SER91L, SER96H, SER99H, THR129L, THR135H, THR164L, THR165H, THR172L, THR178L, THR180L, THR183H, THR31L, THR85L, THR97L, TRP103H, TRP33H, TRP35L, TRP36H, TRP47H, TYR102H, TYR173L, TYR176H, TYR186L, TYR36L, TYR49L, TYR55L, TYR59H, TYR86L, TYR87L, TYR91H, TYR96L, VAL115L, VAL121H, VAL132L, VAL133L, VAL142H, VAL163H, VAL163L, VAL169H, VAL181H, VAL182H, VAL184H, VAL211H, VAL2H, VAL33L, VAL37H, VAL89H, VAL98H