3P08

crystal structure of the human btk kinase domain

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 152
  • Norm. En. per Res.: -2.6599
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-53.7986	-2.3675	-348.132	-404.2981	152	35	10	15075	10	51	53

Interface residues

• A-B: ALA428A, ALA523A, ALA523B, ARG468A, ARG468B, ARG487A, ARG487B, ARG525A, ARG525B, ARG544A, ARG544B, ARG562A, ARG562B, ARG600A, ASN484A, ASN484B, ASN526A, ASN526B, ASN603A, ASN603B, ASP398A, ASP398B, ASP440A, ASP440B, ASP521A, ASP521B, ASP539A, ASP539B, ASP548B, ASP549B, CYS464A, CYS464B, GLN412A, GLN412B, GLN467A, GLN467B, GLU407A, GLU407B, GLU434A, GLU434B, GLU439A, GLU439B, GLU441A, GLU441B, GLU445A, GLU445B, GLU550B, GLU589A, GLU589B, GLU599A, GLU599B, GLU605B, GLY409A, GLY409B, GLY411A, GLY411B, GLY414A, GLY414B, GLY419A, GLY419B, GLY435A, GLY435B, GLY541A, GLY594A, GLY594B, ILE397A, ILE397B, ILE429A, ILE429B, ILE432A, ILE470A, ILE470B, ILE472A, ILE472B, ILE473A, ILE473B, LEU402A, LEU402B, LEU405A, LEU405B, LEU408A, LEU408B, LEU483A, LEU483B, LEU528A, LEU542A, LEU547B, LYS400A, LYS400B, LYS406A, LYS406B, LYS417A, LYS417B, LYS430A, LYS430B, LYS433A, LYS433B, LYS558A, LYS595A, LYS595B, MET431A, MET431B, MET437A, MET437B, MET449A, MET596A, MET596B, PHE413A, PHE413B, PHE442A, PHE471A, PHE471B, PHE540A, PHE559A, PHE559B, PHE601A, PHE601B, PRO399A, PRO399B, PRO469A, PRO469B, PRO560A, PRO560B, PRO597A, PRO597B, SER436A, SER436B, SER438A, SER438B, SER538A, SER543A, SER543B, SER604B, THR410A, THR410B, THR474A, THR552B, THR602A, THR602B, TRP563A, TRP563B, TYR418A, TYR418B, TYR545B, TYR551B, TYR598A, VAL415A, VAL415B, VAL416A, VAL416B, VAL561A, VAL561B