3OZM

crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate

• Total interactions analyzed: 28
• Total true interactions: 16
• Strongest Interaction:
  • Chains: A-G
  • Int. Res.: 172
  • Norm. En. per Res.: -3.7898
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-17.8914	-41.9361	-119.877	-179.7044	66	7	0	4203	8	28	22
A-D	-18.0506	-12.9274	-114.827	-145.8049	61	7	0	4025	8	28	22
A-F	-72.3096	0.9911	-385.128	-456.4465	143	20	10	14245	0	19	36
A-G	-82.8147	-96.2726	-472.757	-651.8444	172	15	6	18469	10	82	66
B-C	-13.9593	-45.3543	-120.716	-180.0296	67	3	0	4177	9	27	22
B-D	-17.506	-49.9154	-126.746	-194.1674	68	5	0	4333	9	27	23
B-E	-72.827	0.9494	-387.899	-459.7765	140	20	10	14310	0	19	36
B-H	-75.3876	-101.2991	-402.187	-578.8737	158	13	8	16010	9	76	59
C-E	-79.7269	-95.5908	-472.659	-647.9767	175	16	9	18398	9	80	65
C-G	-72.0842	0.9946	-386.19	-457.2796	141	15	10	13831	0	20	35
D-F	-74.4683	-89.5025	-392.002	-555.9728	159	16	6	15914	8	76	59
D-H	-71.8734	1.0001	-382.939	-453.8123	142	20	10	13993	0	18	35
E-G	-19.8357	-43.7528	-116.821	-180.4095	66	8	0	4167	8	28	22
E-H	-19.817	-12.8067	-113.562	-146.1857	61	8	0	4051	8	28	22
F-G	-18.1215	-43.5013	-119.666	-181.2889	66	5	0	4271	8	28	23
F-H	-15.6771	-49.6624	-122.192	-187.5314	66	4	0	4190	9	28	23

Interface residues

• A-C: ALA194C, ALA211A, ALA213A, ALA243A, ALA243C, ALA294C, ALA295C, ALA297C, ALA300C, ARG179A, ARG189C, ARG208A, ARG216A, ARG216C, ARG239A, ARG239C, ARG242C, ARG249C, ASP195C, ASP210A, ASP219C, ASP233A, ASP234A, ASP269C, ASP272C, CYS223C, GLN244A, GLN244C, GLU197C, GLU220C, GLU236A, GLY193C, GLY207A, GLY222C, GLY237A, GLY245C, GLY386A, HIS135C, HIS209A, HIS298C, ILE232A, ILE235A, ILE240A, ILE250C, ILE266C, ILE271C, LEU212A, LEU215A, LEU215C, LEU230A, LEU241A, LEU299C, MET214A, MET387A, PHE134C, PRO247C, PRO323C, PRO325C, SER231A, SER296C, THR246C, TRP225C, TYR224C, VAL196C, VAL248C, VAL273C
• A-D: ALA194A, ALA211D, ALA213D, ALA243A, ALA243D, ALA294A, ALA295A, ALA297A, ALA300A, ARG179D, ARG189A, ARG208D, ARG216A, ARG216D, ARG239A, ARG239D, ARG242A, ARG249A, ASP195A, ASP210D, ASP219A, ASP233D, ASP234D, ASP269A, ASP272A, CYS223A, GLN244A, GLN244D, GLU197A, GLU220A, GLU236D, GLY193A, GLY207D, GLY222A, GLY237D, GLY245A, HIS209D, HIS298A, ILE232D, ILE235D, ILE240D, ILE250A, ILE266A, ILE271A, LEU212D, LEU215A, LEU215D, LEU230D, LEU241D, LEU299A, MET214D, PRO247A, PRO325A, SER231D, SER296A, THR246A, TRP225A, TYR224A, VAL196A, VAL248A, VAL273A
• A-F: ALA121A, ALA121F, ALA261A, ALA261F, ALA287A, ALA287F, ALA289A, ALA289F, ALA292A, ALA292F, ALA294A, ALA294F, ALA295A, ALA295F, ALA297A, ALA297F, ALA320A, ALA320F, ALA321A, ALA321F, ALA79A, ALA79F, ARG100A, ARG100F, ARG137A, ARG137F, ARG242F, ARG259A, ARG259F, ARG267A, ARG267F, ASN123A, ASN123F, ASN260A, ASN260F, ASN263A, ASN263F, ASN80A, ASN80F, ASN82A, ASN82F, ASP264A, ASP264F, ASP269A, ASP269F, ASP77A, ASP77F, GLN124A, GLN124F, GLN128A, GLN128F, GLN357A, GLU286A, GLU286F, GLU76A, GLU76F, GLY119A, GLY119F, GLY131A, GLY131F, GLY132A, GLY132F, HIS135A, HIS135F, HIS298A, HIS298F, HIS317A, HIS317F, HIS324A, HIS324F, HIS86A, HIS86F, HIS90A, HIS90F, ILE126A, ILE126F, ILE266A, ILE266F, ILE284A, ILE284F, ILE290A, ILE290F, ILE81A, ILE81F, LEU114A, LEU114F, LEU129A, LEU129F, LEU130A, LEU130F, LEU274A, LEU274F, LEU288A, LEU288F, LEU299A, LEU299F, LEU318A, LEU318F, LEU3A, LEU3F, LEU84A, LEU84F, LYS118A, LYS118F, LYS133A, LYS133F, LYS87A, LYS87F, MET122A, MET122F, PHE134A, PHE134F, PHE262A, PHE262F, PRO125A, PRO125F, PRO323A, PRO323F, PRO78A, PRO78F, SER291A, SER291F, SER293A, SER293F, SER296A, SER296F, SER2A, SER2F, SER322A, SER322F, THR136A, THR136F, THR258A, THR285A, THR285F, TRP115A, TRP115F, TRP85A, TRP85F, TYR127A, TYR127F, TYR83A, TYR83F
• A-G: ALA105A, ALA105G, ALA202A, ALA202G, ALA261A, ALA261G, ALA270A, ALA270G, ALA27A, ALA27G, ALA380A, ALA380G, ALA383A, ALA383G, ALA59A, ALA59G, ALA64A, ALA64G, ARG100A, ARG100G, ARG208A, ARG208G, ARG239A, ARG239G, ARG259A, ARG259G, ARG267A, ARG267G, ARG280A, ARG280G, ARG63A, ARG63G, ARG95A, ARG95G, ASN203A, ASN203G, ASN255A, ASN255G, ASN260A, ASN260G, ASN263A, ASN263G, ASN268A, ASN268G, ASN82A, ASN96A, ASN96G, ASP233A, ASP233G, ASP234A, ASP234G, ASP264A, ASP264G, ASP57A, ASP57G, ASP67A, ASP67G, GLN204A, GLN204G, GLN72A, GLN72G, GLU228A, GLU228G, GLU236A, GLU236G, GLU254A, GLU254G, GLU378A, GLU378G, GLU92A, GLU92G, GLY103A, GLY103G, GLY237A, GLY237G, GLY26A, GLY26G, GLY28A, GLY28G, GLY377A, GLY377G, GLY382A, GLY382G, GLY384A, GLY384G, GLY386A, GLY386G, GLY54A, GLY54G, GLY91A, GLY91G, GLY98A, GLY98G, HIS385A, HIS385G, HIS86A, HIS86G, HIS90A, HIS90G, HIS99A, HIS99G, ILE104A, ILE104G, ILE232A, ILE232G, ILE235A, ILE235G, ILE240G, ILE381A, ILE381G, ILE65A, ILE65G, LEU206A, LEU230G, LEU256A, LEU256G, LEU58A, LEU58G, LEU61A, LEU61G, LEU84A, LEU97A, LEU97G, LYS62A, LYS62G, LYS87A, LYS87G, MET387A, MET387G, PHE89A, PHE89G, PRO379A, PRO379G, PRO55A, PRO55G, PRO71G, SER101A, SER101G, SER205A, SER205G, SER231A, SER231G, SER25A, SER25G, SER94A, SER94G, THR258A, THR258G, TRP148A, TRP148G, TRP375A, TRP375G, TRP85A, TRP85G, TYR257A, TYR257G, TYR265A, TYR265G, TYR56A, TYR56G, TYR83A, TYR83G, VAL102A, VAL102G, VAL60A, VAL60G, VAL68A, VAL68G, VAL88A, VAL88G, VAL93A, VAL93G
• B-C: ALA194B, ALA211C, ALA213C, ALA243B, ALA243C, ALA294B, ALA295B, ALA297B, ALA300B, ARG179C, ARG189B, ARG208C, ARG216B, ARG216C, ARG239B, ARG239C, ARG242B, ARG249B, ASP195B, ASP210C, ASP219B, ASP233C, ASP234C, ASP269B, ASP272B, CYS223B, GLN244B, GLN244C, GLU197B, GLU220B, GLU236C, GLY193B, GLY207C, GLY222B, GLY237C, GLY245B, GLY386C, HIS135B, HIS209C, HIS298B, ILE232C, ILE235C, ILE240C, ILE250B, ILE266B, ILE271B, LEU212C, LEU215B, LEU215C, LEU230C, LEU241C, LEU299B, LYS133B, MET214C, MET387C, PHE134B, PRO247B, PRO323B, PRO325B, SER231C, SER296B, THR136B, THR246B, TYR224B, VAL196B, VAL248B, VAL273B
• B-D: ALA194D, ALA211B, ALA213B, ALA243B, ALA243D, ALA294D, ALA295D, ALA297D, ALA300D, ARG179B, ARG189D, ARG208B, ARG216B, ARG216D, ARG239B, ARG239D, ARG242D, ARG249D, ASP195D, ASP210B, ASP219D, ASP233B, ASP234B, ASP269D, ASP272D, CYS223D, GLN244B, GLN244D, GLU197D, GLU220D, GLU236B, GLY193D, GLY207B, GLY222D, GLY237B, GLY245D, GLY386B, HIS135D, HIS209B, HIS298D, ILE232B, ILE235B, ILE240B, ILE250D, ILE266D, ILE271D, LEU212B, LEU215B, LEU215D, LEU230B, LEU241B, LEU299D, LYS133D, MET214B, MET387B, PHE134D, PRO247D, PRO323D, PRO325D, SER231B, SER296D, THR136D, THR246D, TRP225D, TYR224D, VAL196D, VAL248D, VAL273D
• B-E: ALA121B, ALA121E, ALA261B, ALA261E, ALA287B, ALA289B, ALA289E, ALA292B, ALA292E, ALA294B, ALA294E, ALA295B, ALA295E, ALA297B, ALA297E, ALA320B, ALA320E, ALA321B, ALA321E, ALA79B, ALA79E, ARG100B, ARG100E, ARG137B, ARG137E, ARG242B, ARG259B, ARG259E, ARG267B, ARG267E, ASN123B, ASN123E, ASN260B, ASN260E, ASN263B, ASN263E, ASN80B, ASN80E, ASN82B, ASN82E, ASP264B, ASP264E, ASP269B, ASP269E, ASP77B, ASP77E, GLN124B, GLN124E, GLN128B, GLN128E, GLU286B, GLU286E, GLU76B, GLU76E, GLY119B, GLY119E, GLY131B, GLY131E, GLY132B, GLY132E, HIS135B, HIS135E, HIS298B, HIS298E, HIS317B, HIS317E, HIS324B, HIS324E, HIS86B, HIS86E, HIS90B, HIS90E, ILE126B, ILE126E, ILE266B, ILE266E, ILE284B, ILE284E, ILE290B, ILE290E, ILE81B, ILE81E, LEU114B, LEU114E, LEU129B, LEU129E, LEU130B, LEU130E, LEU274E, LEU288B, LEU288E, LEU299B, LEU299E, LEU318B, LEU318E, LEU3B, LEU3E, LEU84B, LEU84E, LYS118B, LYS118E, LYS133B, LYS133E, LYS87B, LYS87E, MET122B, MET122E, PHE134B, PHE134E, PHE262B, PHE262E, PRO125B, PRO125E, PRO323B, PRO323E, PRO78B, PRO78E, SER291B, SER291E, SER293B, SER293E, SER296B, SER296E, SER2B, SER2E, SER322B, SER322E, THR136B, THR136E, THR258B, THR285B, THR285E, TRP115B, TRP115E, TRP85B, TRP85E, TYR127B, TYR127E, TYR83B, TYR83E
• B-H: ALA105B, ALA105H, ALA202B, ALA202H, ALA261B, ALA261H, ALA270H, ALA27B, ALA27H, ALA380B, ALA380H, ALA383B, ALA59B, ALA59H, ALA64B, ALA64H, ARG100B, ARG100H, ARG176H, ARG208B, ARG208H, ARG239B, ARG239H, ARG259B, ARG259H, ARG267B, ARG267H, ARG280B, ARG280H, ARG63B, ARG63H, ARG95B, ARG95H, ASN203B, ASN203H, ASN255B, ASN255H, ASN260B, ASN260H, ASN263B, ASN263H, ASN268B, ASN268H, ASN80H, ASN82H, ASN96B, ASN96H, ASP233B, ASP233H, ASP234B, ASP234H, ASP264B, ASP264H, ASP57B, ASP57H, ASP67B, ASP67H, GLN204B, GLN204H, GLN72H, GLU228B, GLU228H, GLU236B, GLU236H, GLU254B, GLU254H, GLU378B, GLU378H, GLU92B, GLU92H, GLY103B, GLY103H, GLY237B, GLY237H, GLY26B, GLY28B, GLY377B, GLY377H, GLY382B, GLY384B, GLY386B, GLY54B, GLY54H, GLY91B, GLY91H, GLY98B, GLY98H, HIS385B, HIS86H, HIS90B, HIS90H, HIS99B, HIS99H, ILE104B, ILE104H, ILE232B, ILE232H, ILE235B, ILE235H, ILE240B, ILE381B, ILE381H, ILE65B, ILE65H, LEU206B, LEU230B, LEU230H, LEU256B, LEU256H, LEU58B, LEU58H, LEU61B, LEU61H, LEU84H, LEU97B, LEU97H, LYS62B, LYS62H, LYS87H, MET387B, PHE89B, PHE89H, PRO379B, PRO379H, PRO55B, PRO55H, SER101B, SER101H, SER205B, SER205H, SER231B, SER231H, SER25B, SER94B, SER94H, THR258B, THR258H, TRP148B, TRP375B, TRP375H, TRP85B, TRP85H, TYR257B, TYR257H, TYR265B, TYR265H, TYR56B, TYR56H, TYR83H, VAL102B, VAL102H, VAL60B, VAL60H, VAL68B, VAL68H, VAL88H, VAL93B, VAL93H
• C-E: ALA105C, ALA105E, ALA202C, ALA202E, ALA261C, ALA261E, ALA270E, ALA27C, ALA27E, ALA380C, ALA380E, ALA383C, ALA383E, ALA59C, ALA59E, ALA64C, ALA64E, ARG100C, ARG100E, ARG208C, ARG208E, ARG239C, ARG239E, ARG259C, ARG259E, ARG267C, ARG267E, ARG280C, ARG280E, ARG63C, ARG63E, ARG95C, ARG95E, ASN203C, ASN203E, ASN255C, ASN255E, ASN260C, ASN260E, ASN263C, ASN263E, ASN268C, ASN268E, ASN80E, ASN82C, ASN82E, ASN96C, ASN96E, ASP233C, ASP233E, ASP234C, ASP234E, ASP264C, ASP264E, ASP57C, ASP57E, ASP67C, ASP67E, GLN204C, GLN204E, GLN72C, GLN72E, GLU228C, GLU228E, GLU236C, GLU236E, GLU254C, GLU254E, GLU378C, GLU378E, GLU92C, GLU92E, GLY103C, GLY103E, GLY237C, GLY237E, GLY26C, GLY26E, GLY28C, GLY28E, GLY377C, GLY377E, GLY382C, GLY382E, GLY384C, GLY384E, GLY386C, GLY386E, GLY54C, GLY54E, GLY91C, GLY91E, GLY98C, GLY98E, HIS385C, HIS385E, HIS86C, HIS86E, HIS90C, HIS90E, HIS99C, HIS99E, ILE104C, ILE104E, ILE232C, ILE232E, ILE235C, ILE235E, ILE240C, ILE381C, ILE381E, ILE65C, ILE65E, LEU206C, LEU206E, LEU230C, LEU230E, LEU256C, LEU256E, LEU58C, LEU58E, LEU61C, LEU61E, LEU84C, LEU84E, LEU97C, LEU97E, LYS62C, LYS62E, LYS87C, LYS87E, MET387C, MET387E, PHE89C, PHE89E, PRO379C, PRO379E, PRO55C, PRO55E, SER101C, SER101E, SER205C, SER205E, SER231C, SER231E, SER25C, SER25E, SER94C, SER94E, THR258C, THR258E, TRP148C, TRP148E, TRP375C, TRP375E, TRP85C, TRP85E, TYR257C, TYR257E, TYR265C, TYR265E, TYR56C, TYR56E, TYR83C, TYR83E, VAL102C, VAL102E, VAL60C, VAL60E, VAL68C, VAL68E, VAL88C, VAL88E, VAL93C, VAL93E
• C-G: ALA121C, ALA121G, ALA261C, ALA261G, ALA287C, ALA289C, ALA289G, ALA292C, ALA292G, ALA294C, ALA294G, ALA295C, ALA295G, ALA297C, ALA297G, ALA320C, ALA320G, ALA321C, ALA321G, ALA79C, ALA79G, ARG100C, ARG100G, ARG137C, ARG137G, ARG259C, ARG259G, ARG267C, ARG267G, ASN123C, ASN123G, ASN260C, ASN260G, ASN263C, ASN263G, ASN80C, ASN80G, ASN82C, ASN82G, ASP264C, ASP264G, ASP269C, ASP269G, ASP77C, ASP77G, GLN124C, GLN124G, GLN128C, GLN128G, GLN357C, GLU286C, GLU286G, GLU76C, GLU76G, GLY119C, GLY119G, GLY131C, GLY131G, GLY132C, GLY132G, HIS135C, HIS135G, HIS298C, HIS298G, HIS317C, HIS317G, HIS324C, HIS324G, HIS86C, HIS86G, HIS90C, HIS90G, ILE126C, ILE126G, ILE266C, ILE266G, ILE284C, ILE284G, ILE290C, ILE290G, ILE81C, ILE81G, LEU114C, LEU114G, LEU129C, LEU129G, LEU130C, LEU130G, LEU274C, LEU274G, LEU288C, LEU288G, LEU299C, LEU299G, LEU318C, LEU318G, LEU3C, LEU3G, LEU84C, LEU84G, LYS118C, LYS118G, LYS133C, LYS133G, LYS87C, LYS87G, MET122C, MET122G, PHE134C, PHE134G, PHE262C, PHE262G, PRO125C, PRO125G, PRO323C, PRO323G, PRO78C, PRO78G, SER291C, SER291G, SER293C, SER293G, SER296C, SER296G, SER2C, SER2G, SER322C, SER322G, THR136C, THR136G, THR258C, THR285C, THR285G, TRP115C, TRP115G, TRP85C, TRP85G, TYR127C, TYR127G, TYR83C, TYR83G
• D-F: ALA105D, ALA105F, ALA202D, ALA202F, ALA261D, ALA261F, ALA270D, ALA270F, ALA27D, ALA27F, ALA380D, ALA380F, ALA383F, ALA59D, ALA59F, ALA64D, ALA64F, ARG100D, ARG100F, ARG176D, ARG208D, ARG208F, ARG239D, ARG239F, ARG259D, ARG259F, ARG267D, ARG267F, ARG280D, ARG280F, ARG63D, ARG63F, ARG95D, ARG95F, ASN203D, ASN203F, ASN255D, ASN255F, ASN260D, ASN260F, ASN263D, ASN263F, ASN268D, ASN268F, ASN96D, ASN96F, ASP233D, ASP233F, ASP234D, ASP234F, ASP264D, ASP264F, ASP57D, ASP57F, ASP67D, ASP67F, GLN204D, GLN204F, GLN72D, GLN72F, GLU228D, GLU228F, GLU236D, GLU236F, GLU254D, GLU254F, GLU378D, GLU378F, GLU92D, GLU92F, GLY103D, GLY103F, GLY237D, GLY237F, GLY26D, GLY26F, GLY28F, GLY377D, GLY377F, GLY382F, GLY384F, GLY386F, GLY54D, GLY54F, GLY91D, GLY91F, GLY98D, GLY98F, HIS238D, HIS385F, HIS86D, HIS90D, HIS90F, HIS99D, HIS99F, ILE104D, ILE104F, ILE232D, ILE232F, ILE235D, ILE235F, ILE381D, ILE381F, ILE65D, ILE65F, LEU206F, LEU230D, LEU230F, LEU256D, LEU256F, LEU58D, LEU58F, LEU61D, LEU61F, LEU97D, LEU97F, LYS62D, LYS62F, LYS87D, MET387F, PHE89D, PHE89F, PRO379D, PRO379F, PRO55D, PRO55F, PRO71D, SER101D, SER101F, SER205D, SER205F, SER231D, SER231F, SER25F, SER94D, SER94F, THR258D, THR258F, TRP148F, TRP375D, TRP375F, TRP85D, TRP85F, TYR257D, TYR257F, TYR265D, TYR265F, TYR56D, TYR56F, TYR83D, VAL102D, VAL102F, VAL60D, VAL60F, VAL68D, VAL68F, VAL88D, VAL93D, VAL93F
• D-H: ALA121D, ALA121H, ALA261D, ALA261H, ALA289D, ALA289H, ALA292D, ALA292H, ALA294D, ALA294H, ALA295D, ALA295H, ALA297D, ALA297H, ALA320D, ALA320H, ALA321D, ALA321H, ALA79D, ALA79H, ARG100D, ARG100H, ARG137D, ARG137H, ARG242D, ARG259D, ARG259H, ARG267D, ARG267H, ASN123D, ASN123H, ASN260D, ASN260H, ASN263D, ASN263H, ASN268D, ASN80D, ASN80H, ASN82D, ASN82H, ASP264D, ASP264H, ASP269D, ASP269H, ASP77D, ASP77H, GLN124D, GLN124H, GLN128D, GLN128H, GLN357D, GLN357H, GLU286D, GLU286H, GLU76D, GLU76H, GLY119D, GLY119H, GLY131D, GLY131H, GLY132D, GLY132H, HIS135D, HIS135H, HIS298D, HIS298H, HIS317D, HIS317H, HIS324D, HIS324H, HIS86D, HIS86H, HIS90D, HIS90H, ILE126D, ILE126H, ILE266D, ILE266H, ILE284D, ILE284H, ILE290D, ILE290H, ILE81D, ILE81H, LEU114D, LEU114H, LEU129D, LEU129H, LEU130D, LEU130H, LEU274H, LEU288D, LEU288H, LEU299D, LEU299H, LEU318D, LEU318H, LEU3D, LEU3H, LEU84D, LEU84H, LYS118D, LYS118H, LYS133D, LYS133H, LYS87D, LYS87H, MET122D, MET122H, PHE134D, PHE134H, PHE262D, PHE262H, PRO125D, PRO125H, PRO323D, PRO323H, PRO78D, PRO78H, SER291D, SER291H, SER293D, SER293H, SER296D, SER296H, SER2D, SER2H, SER322D, SER322H, THR136D, THR136H, THR258H, THR285D, THR285H, TRP115D, TRP115H, TRP85D, TRP85H, TYR127D, TYR127H, TYR83D, TYR83H
• E-G: ALA194G, ALA211E, ALA213E, ALA243E, ALA243G, ALA294G, ALA295G, ALA297G, ALA300G, ARG179E, ARG189G, ARG208E, ARG216E, ARG216G, ARG239E, ARG239G, ARG242G, ARG249G, ASP195G, ASP210E, ASP219G, ASP233E, ASP234E, ASP269G, ASP272G, CYS223G, GLN244E, GLN244G, GLU197G, GLU220G, GLU236E, GLY193G, GLY207E, GLY222G, GLY237E, GLY245G, GLY386E, HIS135G, HIS209E, HIS298G, ILE232E, ILE235E, ILE240E, ILE250G, ILE266G, ILE271G, LEU212E, LEU215E, LEU215G, LEU230E, LEU241E, LEU299G, MET214E, MET387E, PHE134G, PRO247G, PRO323G, PRO325G, SER231E, SER296G, THR246G, TRP225G, TYR224G, VAL196G, VAL248G, VAL273G
• E-H: ALA194E, ALA211H, ALA213H, ALA243E, ALA243H, ALA294E, ALA295E, ALA297E, ALA300E, ARG179H, ARG189E, ARG208H, ARG216E, ARG216H, ARG239E, ARG239H, ARG242E, ARG249E, ASP195E, ASP210H, ASP219E, ASP233H, ASP234H, ASP269E, ASP272E, CYS223E, GLN244E, GLN244H, GLU197E, GLU220E, GLU236H, GLY193E, GLY207H, GLY222E, GLY237H, GLY245E, HIS209H, HIS298E, ILE232H, ILE235H, ILE240H, ILE250E, ILE266E, ILE271E, LEU212H, LEU215E, LEU215H, LEU230H, LEU241H, LEU299E, MET214H, PRO247E, PRO325E, SER231H, SER296E, THR246E, TRP225E, TYR224E, VAL196E, VAL248E, VAL273E
• F-G: ALA194F, ALA211G, ALA213G, ALA243F, ALA243G, ALA294F, ALA295F, ALA297F, ALA300F, ARG179G, ARG189F, ARG208G, ARG216F, ARG216G, ARG239F, ARG239G, ARG242F, ARG249F, ASP195F, ASP210G, ASP219F, ASP233G, ASP234G, ASP269F, ASP272F, CYS223F, GLN244F, GLN244G, GLU197F, GLU220F, GLU236G, GLY193F, GLY207G, GLY222F, GLY237G, GLY245F, GLY386G, HIS135F, HIS209G, HIS298F, ILE232G, ILE235G, ILE240G, ILE250F, ILE266F, ILE271F, LEU212G, LEU215F, LEU215G, LEU230G, LEU241G, LEU299F, MET214G, MET387G, PHE134F, PRO247F, PRO323F, PRO325F, SER231G, SER296F, THR136F, THR246F, TYR224F, VAL196F, VAL248F, VAL273F
• F-H: ALA194H, ALA211F, ALA213F, ALA243F, ALA243H, ALA294H, ALA295H, ALA297H, ALA300H, ARG179F, ARG189H, ARG208F, ARG216F, ARG216H, ARG239F, ARG239H, ARG242H, ARG249H, ASP195H, ASP210F, ASP219H, ASP233F, ASP234F, ASP269H, ASP272H, CYS223H, GLN244F, GLN244H, GLU197H, GLU220H, GLU236F, GLY193H, GLY207F, GLY222H, GLY237F, GLY245H, GLY386F, HIS135H, HIS209F, HIS298H, ILE232F, ILE235F, ILE240F, ILE250H, ILE266H, ILE271H, LEU212F, LEU215F, LEU215H, LEU230F, LEU241F, LEU299H, MET214F, MET387F, PHE134H, PRO247H, PRO323H, PRO325H, SER231F, SER296H, THR246H, TRP225H, TYR224H, VAL196H, VAL248H, VAL273H