3OS8

estrogen receptor

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 42
  • Norm. En. per Res.: -2.8843
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-13.7285	-52.0469	-55.367	-121.1425	42	0	0	2024	2	24	22
A-C	-15.9932	67.3262	-371.138	-319.805	149	10	11	15959	0	43	57
A-D	0.0	0.0	-26.0788	-26.0788	21	3	0	1146	0	10	9
B-C	0.0	0.0	-20.014	-20.014	20	4	0	1042	0	10	9
B-D	-39.0152	58.4719	-399.284	-379.8272	149	19	11	16564	1	44	56

Interface residues

• A-B: ARG372A, ARG372B, ASP374A, ASP374B, ASP538A, ASP538B, ASP545A, ASP545B, GLU542A, GLU542B, HIS373A, HIS373B, HIS377A, HIS377B, LEU462A, LEU462B, LEU539A, LEU539B, LEU541A, LEU541B, LYS467A, LYS467B, MET543A, MET543B, PHE461A, PHE461B, SER463A, SER463B, SER464A, SER464B, SER468A, SER468B, THR371A, THR371B, THR460A, THR460B, THR465A, THR465B, TYR537A, TYR537B, VAL376A, VAL376B
• A-C: ALA430A, ALA430C, ALA505A, ALA505C, ARG412C, ARG434A, ARG434C, ARG477A, ARG477C, ARG503A, ARG503C, ARG515A, ARG515C, ASN455A, ASN455C, ASN519A, ASN519C, ASP426A, ASP426C, ASP473A, ASP473C, ASP480A, ASP480C, ASP484A, ASP484C, CYS381A, CYS381C, GLN498A, GLN498C, GLN499A, GLN499C, GLN500A, GLN500C, GLN502A, GLN502C, GLN506A, GLN506C, GLU385A, GLU385C, GLU423A, GLU423C, GLU523A, GLU523C, GLY457A, GLY457C, GLY521A, GLY521C, HIS377A, HIS476A, HIS476C, HIS488A, HIS501A, HIS501C, HIS513A, HIS513C, HIS516A, HIS516C, HIS524C, ILE424A, ILE424C, ILE451A, ILE451C, ILE452A, ILE452C, ILE475A, ILE475C, ILE482A, ILE482C, ILE487A, ILE487C, ILE510A, ILE510C, ILE514A, ILE514C, LEU378C, LEU428A, LEU428C, LEU429A, LEU429C, LEU448A, LEU448C, LEU454A, LEU454C, LEU462A, LEU462C, LEU469A, LEU469C, LEU479A, LEU479C, LEU486A, LEU486C, LEU497A, LEU497C, LEU504A, LEU504C, LEU507A, LEU507C, LEU508A, LEU508C, LEU509A, LEU509C, LEU511A, LEU511C, LYS472A, LYS472C, LYS481A, LYS481C, LYS520A, LYS520C, MET427A, MET427C, MET437A, MET437C, MET438A, MET438C, MET517A, MET517C, MET522A, MET522C, PHE435A, PHE435C, PHE461A, PHE461C, SER432A, SER432C, SER433A, SER433C, SER456A, SER456C, SER463A, SER463C, SER512A, SER512C, SER518A, SER518C, THR431A, THR431C, THR460A, THR460C, THR483A, THR483C, THR485A, THR485C, TYR459A, TYR459C, TYR526A, TYR526C, VAL458A, VAL458C
• A-D: ARG412D, ASN413D, ASN532A, ASP538A, CYS417D, CYS530A, GLU419D, GLU423D, GLY415D, GLY420D, LEU539A, LYS416D, LYS529A, LYS531A, MET421D, MET528A, MET528D, SER536A, VAL418D, VAL422D, VAL533A
• B-C: ARG412C, ASN413C, ASN532B, ASP538B, CYS417C, CYS530B, GLU419C, GLU423C, GLY415C, GLY420C, LEU539B, LYS416C, LYS529B, LYS531B, MET421C, MET528B, SER536B, VAL418C, VAL422C, VAL533B
• B-D: ALA430B, ALA430D, ALA505B, ALA505D, ARG412D, ARG434B, ARG434D, ARG477B, ARG477D, ARG503B, ARG503D, ARG515B, ARG515D, ASN455B, ASN455D, ASN519B, ASN519D, ASP426B, ASP426D, ASP473B, ASP473D, ASP480B, ASP480D, ASP484B, ASP484D, CYS381B, CYS381D, GLN498B, GLN498D, GLN499B, GLN499D, GLN500B, GLN500D, GLN502B, GLN502D, GLN506B, GLN506D, GLU385B, GLU385D, GLU423B, GLU423D, GLU523B, GLU523D, GLY457B, GLY457D, GLY521B, GLY521D, HIS377B, HIS377D, HIS476B, HIS476D, HIS488B, HIS488D, HIS501B, HIS501D, HIS513B, HIS513D, HIS516B, HIS516D, HIS524D, ILE424B, ILE424D, ILE451B, ILE451D, ILE452B, ILE452D, ILE475B, ILE475D, ILE482B, ILE482D, ILE487B, ILE487D, ILE510B, ILE510D, ILE514B, ILE514D, LEU378D, LEU428B, LEU428D, LEU429B, LEU429D, LEU448B, LEU448D, LEU454B, LEU454D, LEU462B, LEU469B, LEU469D, LEU479B, LEU479D, LEU486B, LEU486D, LEU497B, LEU497D, LEU504B, LEU504D, LEU507B, LEU507D, LEU508B, LEU508D, LEU509B, LEU509D, LEU511B, LEU511D, LYS472B, LYS472D, LYS481B, LYS481D, LYS520B, LYS520D, MET427B, MET427D, MET437B, MET437D, MET438B, MET438D, MET517B, MET517D, MET522B, MET522D, PHE435B, PHE435D, PHE461B, PHE461D, SER432B, SER432D, SER433B, SER433D, SER456B, SER456D, SER463B, SER512B, SER512D, SER518B, SER518D, THR431B, THR431D, THR460B, THR460D, THR483B, THR483D, THR485B, THR485D, TYR459B, TYR459D, TYR526B, TYR526D, VAL458B, VAL458D