3OLJ

crystal structure of human ribonucleotide reductase subunit m2 (hrrm2)

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 160
  • Norm. En. per Res.: -3.0032
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	1	9
A-C	0.0	20.2218	-45.6298	-25.408	35	6	0	1606	3	18	15
A-D	-78.7765	-37.7385	-363.99	-480.505	160	17	11	15137	19	51	29
B-C	-81.5188	-36.2399	-363.779	-481.5377	161	17	10	15058	19	50	30
B-D	0.0	19.3687	-47.2727	-27.904	37	6	0	1721	2	18	14

Interface residues

• A-B: LYS111B, PHE101A
• A-C: ALA99C, ARG124A, ARG264C, ASP108C, ASP112A, GLN114A, GLU105C, GLU106C, GLU117A, GLU260C, GLY254C, HIS115A, ILE113A, LEU109C, LEU255C, LEU261C, LYS111A, LYS111C, LYS185A, LYS247C, MET175C, PHE101C, PHE244C, PHE257C, PRO253C, SER100C, SER110A, SER110C, SER118A, SER258C, THR103C, THR256C, TRP102C, TRP116A, VAL107C
• A-D: ALA104A, ALA104D, ALA135A, ALA135D, ALA136A, ALA136D, ALA158A, ALA158D, ALA167A, ALA167D, ALA196A, ALA196D, ALA97A, ALA97D, ALA99A, ALA99D, ARG148A, ARG148D, ARG159A, ARG159D, ARG190A, ARG190D, ARG78A, ARG78D, ARG79A, ARG79D, ASN142A, ASN142D, ASN144A, ASN144D, ASN170A, ASN170D, ASN195A, ASN195D, ASP138A, ASP138D, ASP181A, ASP181D, CYS160A, CYS160D, GLN151A, GLN151D, GLN154A, GLN154D, GLN165A, GLN165D, GLU105A, GLU105D, GLU106D, GLU143A, GLU143D, GLU147A, GLU147D, GLU157A, GLU157D, GLU169A, GLU169D, GLU174A, GLU174D, GLU191A, GLU191D, GLU198A, GLU198D, GLU86A, GLU98A, GLU98D, GLY139A, GLY139D, GLY163A, GLY163D, HIS172A, HIS172D, ILE140A, ILE140D, ILE166A, ILE166D, ILE171A, ILE171D, ILE180A, ILE180D, ILE197A, ILE197D, ILE214A, ILE214D, ILE82A, ILE82D, ILE85A, ILE85D, LEU145A, LEU145D, LEU178A, LEU178D, LEU179A, LEU179D, LEU193A, LEU193D, LEU211A, LEU211D, LYS95A, LYS95D, MET168A, MET168D, MET175A, MET175D, PHE101A, PHE101D, PHE161A, PHE161D, PHE164A, PHE164D, PHE192A, PHE192D, PHE194A, PHE194D, PHE80A, PHE80D, PHE83A, PHE83D, PRO187A, PRO187D, PRO77A, PRO77D, PRO84A, PRO84D, SER100A, SER100D, SER137A, SER137D, SER150A, SER150D, SER173A, SER173D, SER177A, SER177D, THR103A, THR103D, THR156A, THR156D, THR182A, THR182D, THR199A, THR199D, TRP102A, TRP102D, TRP91A, TRP91D, TYR162A, TYR162D, TYR176A, TYR176D, TYR94A, TYR94D, VAL141A, VAL141D, VAL146A, VAL146D, VAL153A, VAL153D, VAL81A, VAL81D
• B-C: ALA104B, ALA104C, ALA135B, ALA135C, ALA136B, ALA136C, ALA158B, ALA158C, ALA167B, ALA167C, ALA196B, ALA196C, ALA97B, ALA97C, ALA99B, ALA99C, ARG148B, ARG148C, ARG159B, ARG159C, ARG190B, ARG190C, ARG78B, ARG78C, ARG79B, ARG79C, ASN142B, ASN142C, ASN144B, ASN144C, ASN170B, ASN170C, ASN195B, ASN195C, ASP138B, ASP138C, ASP181B, ASP181C, CYS160B, CYS160C, GLN151B, GLN151C, GLN154B, GLN154C, GLN165B, GLN165C, GLU105B, GLU105C, GLU106C, GLU143B, GLU143C, GLU147B, GLU147C, GLU157B, GLU157C, GLU169B, GLU169C, GLU174B, GLU174C, GLU191B, GLU191C, GLU198B, GLU198C, GLU86B, GLU86C, GLU98B, GLU98C, GLY139B, GLY139C, GLY163B, GLY163C, HIS172B, HIS172C, ILE140B, ILE140C, ILE166B, ILE166C, ILE171B, ILE171C, ILE180B, ILE180C, ILE197B, ILE197C, ILE214B, ILE214C, ILE82B, ILE82C, ILE85B, ILE85C, LEU145B, LEU145C, LEU178B, LEU178C, LEU179B, LEU179C, LEU193B, LEU193C, LEU211B, LEU211C, LYS95B, LYS95C, MET168B, MET168C, MET175B, MET175C, PHE101B, PHE101C, PHE161B, PHE161C, PHE164B, PHE164C, PHE192B, PHE192C, PHE194B, PHE194C, PHE80B, PHE80C, PHE83B, PHE83C, PRO187B, PRO187C, PRO77B, PRO77C, PRO84B, PRO84C, SER100B, SER100C, SER137B, SER137C, SER150B, SER150C, SER173B, SER173C, SER177B, SER177C, THR103B, THR103C, THR156B, THR156C, THR182B, THR182C, THR199B, THR199C, TRP102B, TRP102C, TRP91B, TRP91C, TYR162B, TYR162C, TYR176B, TYR176C, TYR94B, TYR94C, VAL141B, VAL141C, VAL146B, VAL146C, VAL153B, VAL153C, VAL81B, VAL81C
• B-D: ALA104D, ALA99D, ARG124B, ARG264D, ASP108D, ASP112B, GLN114B, GLU105D, GLU106D, GLU117B, GLU260D, GLY254D, HIS115B, ILE113B, LEU109D, LEU255D, LEU261D, LYS111B, LYS111D, LYS185B, LYS247D, LYS96D, MET175D, PHE101D, PHE244D, PHE257D, PRO253D, SER100D, SER110B, SER110D, SER118B, SER258D, THR103D, THR256D, TRP102D, TRP116B, VAL107D