3OJY

crystal structure of human complement component c8

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 298
  • Norm. En. per Res.: -3.3203
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-142.0855	-270.4831	-576.895	-989.4637	298	47	3	24428	24	154	142
A-C	-33.1325	-80.6353	383.945	270.1771	123	10	5	11020	6	40	34
B-C	0.0	0.0	-0.0353	-0.0353	4	0	0	15	0	1	3

Interface residues

• A-B: ALA105A, ALA122B, ALA189A, ALA191A, ALA269A, ALA377B, ALA385B, ALA401B, ALA407B, ALA74B, ALA99B, ARG102B, ARG103B, ARG104A, ARG140B, ARG156A, ARG177A, ARG220B, ARG226B, ARG227B, ARG261A, ARG266B, ARG269B, ARG274A, ARG280B, ARG284B, ARG29B, ARG340A, ARG362B, ARG374B, ARG414A, ARG418A, ARG439A, ARG450A, ARG466B, ARG530A, ARG547A, ARG78B, ARG81A, ASN100B, ASN126B, ASN152A, ASN360B, ASN405B, ASN47B, ASN86A, ASN87B, ASN90B, ASP102A, ASP107A, ASP109A, ASP10B, ASP113B, ASP138B, ASP171A, ASP192A, ASP219B, ASP276A, ASP277A, ASP281B, ASP285B, ASP341A, ASP358B, ASP368B, ASP400B, ASP428A, ASP468B, ASP509A, ASP50B, ASP55B, ASP69A, ASP89B, ASP91B, ASP94B, ASP97B, CYS101B, CYS110A, CYS11B, CYS147A, CYS345A, CYS46B, CYS544A, CYS56B, CYS73B, CYS85A, CYS86B, CYS92B, GLN114B, GLN146A, GLN265B, GLN267A, GLN353A, GLN37B, GLN387B, GLN403B, GLN432A, GLN451A, GLN476B, GLN550A, GLN68A, GLN75B, GLN95B, GLU108A, GLU111B, GLU12B, GLU133B, GLU148A, GLU154A, GLU157A, GLU188A, GLU198A, GLU262B, GLU278B, GLU379B, GLU388B, GLU397B, GLU430A, GLU436A, GLU447A, GLU44B, GLU52B, GLU54B, GLU98B, GLY117B, GLY119B, GLY124B, GLY134B, GLY144A, GLY145A, GLY153A, GLY194A, GLY221B, GLY287B, GLY315A, GLY318A, GLY319A, GLY351A, GLY375B, GLY376B, GLY417A, GLY43B, GLY464B, GLY474B, GLY477B, GLY510A, GLY546A, GLY77B, GLY88B, GLY93B, HIS139B, HIS186A, HIS223B, HIS260B, HIS270A, HIS310A, HIS380B, HIS42B, HIS435A, HIS440A, HIS82A, ILE104B, ILE106A, ILE118B, ILE125B, ILE128A, ILE195A, ILE214B, ILE278A, ILE342A, ILE352A, ILE381B, ILE427A, ILE9B, LEU121B, LEU137B, LEU13B, LEU183A, LEU190A, LEU282B, LEU369B, LEU372B, LEU384B, LEU389B, LEU457A, LEU461A, LEU478B, LEU83A, LYS107B, LYS174A, LYS178A, LYS184A, LYS209A, LYS211A, LYS222B, LYS265A, LYS272A, LYS275A, LYS27B, LYS28B, LYS361B, LYS421A, LYS463B, LYS51B, LYS80A, MET112B, MET273A, MET279A, MET317A, MET431A, MET7B, PHE132B, PHE156B, PHE176A, PHE182A, PHE187A, PHE199A, PHE263A, PHE263B, PHE283B, PHE286B, PHE429A, PHE48B, PHE71B, PRO135B, PRO406B, PRO433A, PRO445A, PRO45B, PRO545A, PRO8B, SER120B, SER123B, SER131B, SER196A, SER197A, SER215B, SER218B, SER314A, SER316A, SER378B, SER415A, SER442A, SER465B, SER475B, SER49B, SER543A, SER96B, THR149A, THR154B, THR193A, THR264A, THR268A, THR309A, THR313A, THR344A, THR382B, THR383B, THR76B, TRP116B, TRP155A, TRP16B, TRP19B, TRP512A, TRP515A, TYR105B, TYR113A, TYR115B, TYR126A, TYR142A, TYR143A, TYR151A, TYR169A, TYR175A, TYR180A, TYR185A, TYR200A, TYR224B, TYR261B, TYR30B, TYR311A, TYR354A, TYR386B, TYR404B, TYR413A, TYR484B, VAL103A, VAL136B, VAL150A, VAL210A, VAL266A, VAL370B, VAL371B, VAL373B, VAL402B, VAL473B, VAL482B, VAL53B, VAL84A
• A-C: ALA102C, ALA123C, ALA35C, ALA39C, ALA50C, ALA63C, ALA99C, ARG100C, ARG122C, ARG156A, ARG159A, ARG166A, ARG379A, ARG381A, ARG414A, ARG418A, ARG41C, ARG49C, ARG70C, ARG80C, ASN152A, ASN423A, ASP161A, ASP172A, ASP178C, ASP73C, ASP85C, CYS164A, CYS40C, CYS76C, GLN125C, GLN44C, GLN46C, GLN78C, GLN81C, GLN95C, GLU114A, GLU121C, GLU154A, GLU157A, GLU165A, GLU173A, GLU179C, GLU378A, GLU45C, GLU51C, GLY101C, GLY124C, GLY170A, GLY373A, GLY374A, GLY375A, GLY37C, GLY396A, GLY61C, GLY84C, GLY87C, HIS104C, HIS175C, ILE13C, ILE411A, ILE75C, LEU118C, LEU120C, LEU126C, LEU158A, LEU167A, LEU177C, LEU33C, LEU420A, LEU43C, LEU55C, LEU72C, LEU89C, LEU93C, LEU94C, LYS129C, LYS371A, LYS376A, LYS421A, LYS71C, PHE160C, PHE162C, PHE176A, PHE42C, PHE69C, PRO117A, PRO424A, SER127C, SER162A, SER38C, SER397A, SER409A, SER415A, SER419A, THR163A, THR377A, THR410A, THR412A, THR53C, THR54C, THR62C, THR68C, THR86C, TRP155A, TRP416A, TRP77C, TYR119C, TYR131C, TYR160A, TYR168A, TYR169A, TYR422A, TYR83C, VAL103C, VAL105C, VAL128C, VAL176C, VAL180C, VAL36C, VAL66C, VAL79C, VAL88C
• B-C: GLN396B, PHE174C, THR383B, VAL180C