3OAA

structure of the e.coli f1-atp synthase inhibited by subunit epsilon

• Total interactions analyzed: 496
• Total true interactions: 97
• Strongest Interaction:
  • Chains: O-P
  • Int. Res.: 223
  • Norm. En. per Res.: -3.397
• Hub Node: A(10)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.0144	-0.0144	2	0	0	11	0	0	0
A-C	0.0	0.0	-0.0081	-0.0081	2	0	0	10	0	1	0
A-D	-78.3211	-26.5548	-343.049	-447.9249	190	32	10	16194	3	39	39
A-E	-75.192	-5.1317	-409.761	-490.0847	182	21	7	18087	2	59	62
A-G	0.0	-23.109	-72.5121	-95.6211	66	2	4	3894	2	20	9
A-H	0.0	7.043	-32.8878	-25.8448	19	0	1	1093	0	1	3
B-E	-50.2326	-25.172	-355.389	-430.7937	199	16	8	16198	5	40	44
B-F	-90.5288	-42.154	-617.905	-750.5878	261	60	15	26814	4	74	72
B-G	0.0	-9.3018	-19.1349	-28.4367	34	0	1	1433	0	10	4
B-H	0.0	-2.0696	-0.0552	-2.1248	4	0	0	27	0	4	0
B-J	0.0	9.9924	-2.7267	7.2657	12	0	0	217	0	16	6
B-N	0.0	0.0	-0.2633	-0.2633	6	0	0	48	0	8	6
C-D	-56.8141	-3.7452	-559.536	-620.0953	257	31	11	25188	0	75	80
C-F	-59.6365	-12.6653	-436.82	-509.1218	234	21	11	20094	4	44	57
C-G	-8.4411	-12.4379	-28.1261	-49.005	42	1	0	1309	1	9	8
C-H	0.0	-6.4748	-53.4381	-59.9129	46	2	5	2492	0	16	12
D-G	0.0	-2.1691	-18.1233	-20.2924	24	0	0	1111	0	9	6
D-H	-5.9655	4.2966	-62.6626	-64.3316	33	4	6	3139	2	6	9
E-F	0.0	0.0	-0.0067	-0.0067	2	0	0	5	0	0	0
E-G	-2.9081	-48.0411	-94.7986	-145.7479	69	9	1	5095	3	15	6
E-U	0.0	-6.8504			10
E-W	0.0	-6.5541			9
E-X	0.0	-15.3469			2
F-G	-4.3147	0.0	-81.2473	-85.562	83	2	2	4328	0	16	8
F-H	-17.1447	-1.9112	-94.6153	-113.6712	46	5	4	4250	0	16	12
F-J	0.0	0.0	-0.1129	-0.1129	7	0	0	36	0	12	9
F-N	0.0	3.2761	-19.6143	-16.3382	12	1	0	954	0	4	10
G-H	-41.9049	-74.5434	-643.86	-760.3083	225	26	30	27979	8	60	62
G-K	0.0	0.0	-0.0007	-0.0007	2	0	0	2	0	3	6
G-O	-10.8965	-6.4917	-71.0115	-88.3996	54	3	0	2838	0	10	9
G-P	0.0	0.0	-0.0724	-0.0724	3	0	0	28	0	8	7
G-U	-4.5187	-5.099			13
H-O	0.0	0.0	-0.0947	-0.0947	3	0	0	29	0	8	7
H-U	0.0	-15.4479			2
I-J	0.0	0.0	-0.0218	-0.0218	2	0	0	14	0	0	0
I-K	0.0	0.0	-0.0057	-0.0057	2	0	0	9	0	1	0
I-L	-72.7892	-32.1349	-327.745	-432.6691	186	19	10	15536	2	38	38
I-M	-94.1579	-12.0137	-440.786	-546.9576	182	36	9	18991	2	59	63
I-O	0.0	-24.0528	-87.7837	-111.8365	69	15	6	4565	2	20	9
I-P	0.0	6.768	-21.7092	-14.9412	17	1	1	879	0	0	3
J-M	-58.8185	-25.8599	-369.344	-454.0224	197	25	9	16505	5	41	44
J-N	-99.9001	-36.7736	-595.622	-732.2957	260	58	15	25968	4	73	69
J-O	0.0	-11.3619	-20.3835	-31.7453	34	0	1	1440	2	10	4
J-P	0.0	-2.2904	-0.138	-2.4284	4	0	0	47	0	3	0
K-L	-54.4613	-6.8528	-536.918	-598.2321	257	38	11	25311	0	77	80
K-N	-64.8733	-12.6903	-442.798	-520.3615	234	20	11	20391	5	44	57
K-O	0.0	-9.543	-18.8061	-28.3491	39	0	0	1035	1	9	7
K-P	-10.5489	-10.6096	-56.5582	-77.7166	45	3	4	2595	0	16	12
L-O	0.0	-2.1641	-20.5441	-22.7082	24	0	0	1188	0	9	6
L-P	0.0	6.8589	-74.5368	-67.6779	33	2	6	3356	2	6	9
M-N	0.0	0.0	-0.0071	-0.0071	2	0	0	5	0	0	0
M-O	0.0	-42.8152	-92.3341	-135.1493	67	12	1	5080	3	15	6
M-c	0.0	-8.5663			10
M-e	0.0	-9.6949			8
M-f	0.0	-18.4833			2
N-O	-5.8574	0.0	-80.4827	-86.3401	81	2	3	4137	0	16	7
N-P	-8.6211	-2.924	-78.1142	-89.6593	46	3	4	3935	0	15	12
N-R	0.0	13.1151			5
O-P	-53.4269	-74.1117	-629.993	-757.5316	223	31	30	27752	8	60	61
O-c	0.0	-3.5923			11
P-c	0.0	-17.1392			2
Q-T	-61.2386	-25.0673			23
Q-U	-81.9665	-10.4494			32
Q-W	0.0	-19.9679			8
Q-X	0.0	7.7183			2
R-U	-41.6291	-28.8066			21
R-V	-89.329	-42.479			37
R-W	0.0	-8.3663			2
R-X	0.0	-2.0399			2
S-T	-64.8845	-11.0556			35
S-V	-70.4278	-20.835			33
S-W	-6.5518	-12.2648			6
S-X	-7.7598	-7.1835			5
T-W	0.0	-2.1955			2
T-X	-6.5376	3.1481			5
U-W	-13.3901	-55.5263			5
V-W	-5.521	0.0			4
V-X	-8.1097	-1.8868			7
W-X	-48.7563	-86.6607			43
Y-b	-71.6339	-27.5998			24
Y-c	-72.7851	-35.2706			36
Y-e	-8.0287	-18.3558			10
Y-f	-3.854	8.0269			3
Z-c	-51.6627	-32.1099			22
Z-d	-67.8984	-36.0607			33
Z-e	0.0	-9.8583			2
Z-f	0.0	-2.1561			2
a-b	-59.4069	-4.2874			35
a-d	-74.1401	-11.6966			33
a-e	0.0	-11.8763			6
a-f	-14.2927	-11.0507			7
b-e	0.0	-2.0444			2
b-f	-5.2816	10.194			6
c-e	-9.6916	-50.92			5
d-e	-3.5926	0.0			2
d-f	-8.2968	-0.823			7
e-f	-46.3037	-79.0734			42

Interface residues

• A-B: ARG278B, PRO280A
• A-C: ARG278A, PRO280C
• A-D: ALA112D, ALA113D, ALA202A, ALA21D, ALA228A, ALA232A, ALA233A, ALA264D, ALA269A, ALA272D, ALA285A, ALA309D, ALA313D, ALA317D, ALA334A, ALA339A, ALA362A, ALA80A, ALA83A, ARG106A, ARG111D, ARG171A, ARG210A, ARG218D, ARG24D, ARG260D, ARG271A, ARG278A, ARG279A, ARG281D, ARG283A, ARG342D, ARG358D, ARG365A, ARG40A, ARG52D, ASN121D, ASN207A, ASN361A, ASP116A, ASP20D, ASP262A, ASP27D, ASP302D, ASP305D, ASP316D, ASP336A, ASP338D, ASP345D, ASP36A, ASP372D, ASP81A, GLN172A, GLN19D, GLN200A, GLN235A, GLN268D, GLN272A, GLN279D, GLN333A, GLN361D, GLN408A, GLN435A, GLN43D, GLN44D, GLN45D, GLU117D, GLU118D, GLU230A, GLU273D, GLU274D, GLU280D, GLU284A, GLU331A, GLU369D, GLU84A, GLY117A, GLY142D, GLY143D, GLY199A, GLY259D, GLY266D, GLY276D, GLY282A, GLY363A, GLY37A, GLY47D, GLY48D, GLY49D, GLY85A, HIS110D, HIS314D, ILE115A, ILE205A, ILE273A, ILE282D, ILE31A, ILE39A, ILE50D, LEU119D, LEU218A, LEU258D, LEU271D, LEU275A, LEU276A, LEU277A, LEU278D, LEU303D, LEU315D, LEU337D, LEU344D, LEU347D, LEU46D, LEU82A, LYS118A, LYS144D, LYS201A, LYS265A, LYS286D, LYS434A, MET261D, MET275D, MET86A, PHE148D, PHE17D, PHE286A, PHE312D, PHE360A, PHE409A, PRO114A, PRO114D, PRO18D, PRO23D, PRO262D, PRO269D, PRO280A, PRO281A, PRO287A, PRO306D, PRO308D, PRO346D, PRO74D, PRO78A, SER115D, SER120D, SER122D, SER203A, SER206A, SER229A, SER231A, SER255D, SER263D, SER274A, SER284D, SER307D, SER33A, SER341D, SER35A, THR204A, THR227A, THR270D, THR283D, THR304D, THR30A, THR310D, THR311D, THR318D, THR340D, TYR116D, TYR267D, TYR26D, TYR354D, TYR436A, TYR79A, VAL107A, VAL108A, VAL208A, VAL209A, VAL223A, VAL225A, VAL22D, VAL25D, VAL265D, VAL268A, VAL277D, VAL32A, VAL34A, VAL38A, VAL42D, VAL51D
• A-E: ALA11E, ALA128A, ALA131A, ALA133A, ALA151E, ALA250E, ALA256E, ALA264E, ALA300E, ALA301A, ALA302A, ALA311A, ALA45A, ALA63A, ARG139A, ARG164A, ARG182E, ARG184E, ARG216E, ARG246E, ARG260E, ARG279A, ARG283A, ARG296A, ARG300A, ARG303A, ARG376A, ARG40A, ARG52E, ARG63E, ARG64E, ARG68A, ASN187E, ASN210E, ASN215E, ASN243E, ASN27A, ASN305A, ASN33E, ASN344A, ASN65A, ASP14E, ASP188E, ASP289A, ASP305E, ASP350A, ASP46A, ASP60E, ASP69A, ASP96E, CYS47A, CYS90A, GLN140A, GLN163A, GLN208E, GLN268E, GLN352A, GLN49A, GLN7E, GLU130A, GLU138A, GLU16E, GLU181E, GLU185E, GLU192E, GLU211E, GLU253E, GLU28A, GLU299A, GLU307A, GLU51A, GLU67A, GLY10E, GLY135A, GLY150E, GLY152E, GLY162A, GLY178E, GLY180E, GLY186E, GLY207E, GLY214E, GLY259E, GLY266E, GLY282A, GLY288A, GLY29A, GLY351A, GLY378A, GLY43A, GLY50A, GLY57E, GLY61E, GLY65E, GLY72A, GLY92A, HIS191E, HIS26A, HIS294A, HIS42A, ILE132A, ILE137A, ILE346A, ILE348A, ILE41A, ILE50E, ILE53A, ILE5E, ILE62A, ILE87E, ILE94A, ILE9E, LEU204E, LEU249E, LEU257E, LEU258E, LEU277A, LEU293A, LEU297A, LEU298A, LEU44A, LEU62E, LEU64A, LEU66A, LEU66E, LEU95A, LYS155E, LYS98E, MET209E, MET261E, MET48A, MET97E, PHE189E, PHE291A, PHE340A, PRO134A, PRO212E, PRO213E, PRO262E, PRO280A, PRO281A, PRO287A, PRO299E, PRO306E, SER141A, SER255E, SER295A, SER307E, SER338A, SER347A, SER58E, SER59E, SER70A, THR156E, THR183E, THR252E, THR343A, THR349A, THR91A, TYR190E, TYR206E, TYR245E, TYR267E, TYR270A, TYR292A, TYR297E, TYR308A, VAL12E, VAL136A, VAL13E, VAL142A, VAL153E, VAL254E, VAL265E, VAL290A, VAL345A, VAL374A, VAL377A, VAL6E, VAL71A, VAL8E, VAL95E
• A-G: ALA22G, ALA27G, ALA283G, ALA284G, ALA285A, ALA28G, ALA334A, ALA339A, ALA405A, ALA410A, ARG268G, ARG271A, ARG278A, ARG279A, ARG283A, ARG7G, ASN15G, ASN265G, ASP141G, ASP336A, ASP412A, ASP414A, GLN261G, GLN269G, GLN333A, GLN408A, GLU24G, GLU275G, GLU284A, GLU402A, GLY282A, GLY282G, GLY288A, GLY335A, ILE19G, ILE272G, ILE279G, LEU275A, LEU276G, LEU403A, LEU413A, LYS18G, LYS21G, LYS30G, LYS33G, MET23G, MET25G, PHE286A, PHE340A, PHE406A, PHE409A, PRO280A, PRO281A, SER271G, SER29G, SER338A, SER407A, SER411A, THR20G, THR273G, THR277G, THR417A, TYR264G, VAL26G, VAL280G, VAL337A
• A-H: ALA115H, ALA117H, ALA119H, ALA410A, ASP111H, ASP113H, ASP412A, GLN116H, GLN408A, GLU120H, LEU121H, LEU413A, PHE406A, PHE409A, SER118H, SER407A, SER411A, TYR114H, VAL112H
• B-E: ALA112E, ALA113E, ALA140E, ALA177B, ALA202B, ALA21E, ALA228B, ALA232B, ALA233B, ALA264E, ALA269B, ALA272E, ALA285B, ALA309E, ALA313E, ALA317E, ALA334B, ALA362B, ALA80B, ALA83B, ARG106B, ARG171B, ARG210B, ARG24E, ARG260E, ARG271B, ARG278B, ARG279B, ARG281E, ARG283B, ARG342E, ARG358E, ARG365B, ARG40B, ARG52E, ARG59B, ASN109B, ASN121E, ASN207B, ASN361B, ASP116B, ASP20E, ASP262B, ASP27E, ASP302E, ASP305E, ASP316E, ASP336B, ASP345E, ASP36B, ASP81B, GLN123E, GLN172B, GLN19E, GLN200B, GLN235B, GLN268E, GLN272B, GLN279E, GLN333B, GLN343E, GLN351E, GLN361E, GLN435B, GLN43E, GLN44E, GLN45E, GLU117E, GLU118E, GLU214B, GLU230B, GLU273E, GLU274E, GLU280E, GLU284B, GLU331B, GLU84B, GLY117B, GLY142E, GLY143E, GLY174B, GLY199B, GLY259E, GLY266E, GLY276E, GLY282B, GLY335B, GLY363B, GLY37B, GLY47E, GLY48E, GLY49E, GLY85B, HIS110E, HIS215B, HIS314E, ILE115B, ILE205B, ILE273B, ILE282E, ILE31B, ILE364B, ILE39B, ILE50E, LEU119E, LEU234B, LEU258E, LEU271E, LEU275B, LEU276B, LEU277B, LEU278E, LEU303E, LEU315E, LEU337E, LEU344E, LEU347E, LEU46E, LEU82B, LYS118B, LYS144E, LYS175B, LYS201B, LYS211B, LYS265B, LYS286E, LYS432B, LYS434B, MET261E, MET275E, MET86B, PHE148E, PHE17E, PHE286B, PHE312E, PHE360B, PRO114E, PRO18E, PRO23E, PRO262E, PRO269E, PRO280B, PRO281B, PRO306E, PRO308E, PRO346E, PRO74E, PRO78B, SER115E, SER120E, SER122E, SER203B, SER206B, SER229B, SER231B, SER255E, SER263E, SER274B, SER284E, SER33B, SER341E, SER35B, THR173B, THR176B, THR204B, THR227B, THR270E, THR283E, THR285E, THR304E, THR310E, THR311E, THR318E, THR332B, THR340E, TYR116E, TYR267E, TYR26E, TYR354E, TYR436B, TYR79B, VAL107B, VAL108B, VAL208B, VAL209B, VAL223B, VAL225B, VAL22E, VAL25E, VAL265E, VAL268B, VAL277E, VAL298E, VAL32B, VAL348E, VAL34B, VAL38B, VAL42E, VAL51E
• B-F: ALA11F, ALA128B, ALA131B, ALA133B, ALA151F, ALA250F, ALA256F, ALA264F, ALA285B, ALA300F, ALA301B, ALA302B, ALA311B, ALA326F, ALA339B, ALA380B, ALA381B, ALA398B, ALA407F, ALA416B, ALA45B, ALA63B, ARG139B, ARG161B, ARG164B, ARG182F, ARG184F, ARG216F, ARG246F, ARG250B, ARG260F, ARG278B, ARG279B, ARG283B, ARG296B, ARG300B, ARG303B, ARG323F, ARG376B, ARG394B, ARG394F, ARG398F, ARG40B, ARG52F, ARG63F, ARG64F, ARG68B, ARG86F, ARG93B, ASN158F, ASN187F, ASN210F, ASN215F, ASN243F, ASN27B, ASN305B, ASN33F, ASN344B, ASN35F, ASN369B, ASN65B, ASN89F, ASP14F, ASP188F, ASP289B, ASP301F, ASP302F, ASP305F, ASP336B, ASP350B, ASP46B, ASP60F, ASP69B, ASP96F, CYS47B, CYS90B, GLN140B, GLN163B, GLN208F, GLN324F, GLN352B, GLN399B, GLN420B, GLN441F, GLN49B, GLN7F, GLU130B, GLU138B, GLU181F, GLU185F, GLU192F, GLU211F, GLU253F, GLU284B, GLU299B, GLU307B, GLU402B, GLU408F, GLU440F, GLU51B, GLU67B, GLY10F, GLY135B, GLY149F, GLY150F, GLY152F, GLY154F, GLY162B, GLY178F, GLY180F, GLY186F, GLY207F, GLY214F, GLY259F, GLY266F, GLY282B, GLY288B, GLY329F, GLY34F, GLY351B, GLY371B, GLY378B, GLY379B, GLY391B, GLY392B, GLY412F, GLY43B, GLY50B, GLY57F, GLY61F, GLY65F, GLY72B, GLY92B, HIS191F, HIS294B, HIS42B, ILE132B, ILE137B, ILE157B, ILE330F, ILE346B, ILE348B, ILE372B, ILE41B, ILE50F, ILE53B, ILE5F, ILE62B, ILE87F, ILE94B, ILE9F, LEU166B, LEU204F, LEU249F, LEU257F, LEU277B, LEU293B, LEU297B, LEU298B, LEU303F, LEU328F, LEU403B, LEU413B, LEU44B, LEU459F, LEU46F, LEU62F, LEU64B, LEU66B, LEU66F, LEU95B, LYS155F, LYS387B, LYS419B, LYS455F, LYS458F, LYS98F, MET156B, MET209F, MET261F, MET445F, MET48B, MET88F, MET97F, PHE176F, PHE189F, PHE286B, PHE291B, PHE340B, PHE354B, PHE410F, PRO134B, PRO158B, PRO212F, PRO213F, PRO262F, PRO280B, PRO281B, PRO287B, PRO299F, PRO306F, PRO308F, PRO342B, PRO370B, PRO94F, SER141B, SER255F, SER263F, SER295B, SER307F, SER327F, SER338B, SER347B, SER373B, SER375B, SER390B, SER413F, SER58F, SER59F, SER70B, THR156F, THR183F, THR252F, THR304F, THR343B, THR349B, THR395B, THR411F, THR417B, THR91B, TYR190F, TYR206F, TYR245F, TYR267F, TYR292B, TYR297F, TYR308B, TYR331F, TYR444F, VAL12F, VAL136B, VAL13F, VAL142B, VAL153F, VAL157F, VAL205F, VAL254F, VAL265F, VAL290B, VAL298F, VAL337B, VAL341B, VAL345B, VAL374B, VAL377B, VAL406F, VAL409F, VAL6F, VAL71B, VAL8F, VAL95F
• B-G: ALA270G, ALA284G, ALA285B, ALA334B, ALA339B, ARG271B, ARG278B, ARG279B, ARG283B, ASP336B, GLN269G, GLN274G, GLN333B, GLU259G, GLU278G, GLU284B, GLY282B, GLY335B, LEU262G, LEU275B, LEU276G, LYS266G, PHE286B, PHE340B, PRO280B, PRO281B, SER281G, SER338B, THR273G, THR277G, THR343B, VAL263G, VAL280G, VAL337B
• B-H: ASP336B, LYS135H, SER338B, VAL337B
• B-J: ASN493B, ASN493J, ASP494B, ASP494J, GLU495B, GLU495J, GLY491B, GLY491J, LYS388B, LYS388J, TYR492B, TYR492J
• B-N: ALA416B, ASP415B, GLU450N, GLU454N, LYS419B, VAL453N
• C-D: ALA11D, ALA131C, ALA133C, ALA151D, ALA250D, ALA256D, ALA25C, ALA264D, ALA285C, ALA300D, ALA301C, ALA302C, ALA326D, ALA339C, ALA375D, ALA380C, ALA381C, ALA396C, ALA398C, ALA410C, ALA416C, ALA45C, ALA55D, ALA63C, ARG139C, ARG161C, ARG164C, ARG182D, ARG184D, ARG216D, ARG246D, ARG260D, ARG278C, ARG279C, ARG283C, ARG296C, ARG300C, ARG303C, ARG323D, ARG376C, ARG394C, ARG394D, ARG398D, ARG401C, ARG418C, ARG52D, ARG63D, ARG64D, ARG68C, ARG86D, ARG93C, ASN187D, ASN210D, ASN215D, ASN243D, ASN27C, ASN305C, ASN33D, ASN344C, ASN35D, ASN65C, ASN89D, ASP143C, ASP14D, ASP188D, ASP289C, ASP301D, ASP302D, ASP305D, ASP336C, ASP350C, ASP372D, ASP380D, ASP412C, ASP414C, ASP415C, ASP46C, ASP60D, ASP69C, ASP96D, CYS47C, CYS90C, GLN140C, GLN163C, GLN208D, GLN324D, GLN352C, GLN368D, GLN399C, GLN420C, GLN49C, GLN7D, GLU130C, GLU138C, GLU16D, GLU181D, GLU185D, GLU192D, GLU211D, GLU253D, GLU284C, GLU299C, GLU381D, GLU402C, GLU408D, GLU51C, GLU67C, GLY10D, GLY135C, GLY149D, GLY150D, GLY152D, GLY154D, GLY162C, GLY180D, GLY186D, GLY214D, GLY259D, GLY266D, GLY282C, GLY288C, GLY29C, GLY329D, GLY34D, GLY351C, GLY371C, GLY378C, GLY378D, GLY379C, GLY391C, GLY412D, GLY43C, GLY50C, GLY57D, GLY61D, GLY65D, GLY72C, GLY92C, HIS191D, HIS26C, HIS294C, HIS42C, ILE132C, ILE137C, ILE325D, ILE330D, ILE346C, ILE348C, ILE372C, ILE373D, ILE374D, ILE376D, ILE393C, ILE41C, ILE50D, ILE5D, ILE87D, ILE94C, ILE9D, LEU204D, LEU249D, LEU257D, LEU258D, LEU277C, LEU293C, LEU297C, LEU298C, LEU328D, LEU377D, LEU397C, LEU403C, LEU413C, LEU44C, LEU62D, LEU64C, LEU66C, LEU66D, LYS155D, LYS371D, LYS387C, LYS98D, MET209D, MET261D, MET379D, MET48C, MET88D, MET97D, PHE189D, PHE286C, PHE291C, PHE340C, PHE354C, PHE406C, PHE409C, PHE410D, PRO134C, PRO212D, PRO213D, PRO262D, PRO280C, PRO281C, PRO287C, PRO299D, PRO306D, PRO370C, SER141C, SER255D, SER263D, SER274C, SER295C, SER327D, SER338C, SER347C, SER373C, SER375C, SER411C, SER58D, SER59D, SER70C, THR156D, THR183D, THR252D, THR343C, THR349C, THR395C, THR411D, THR417C, THR91C, TYR190D, TYR206D, TYR245D, TYR267D, TYR270C, TYR292C, TYR297D, TYR308C, TYR331D, TYR400C, TYR444D, VAL12D, VAL136C, VAL13D, VAL142C, VAL153D, VAL157D, VAL254D, VAL265D, VAL290C, VAL337C, VAL345C, VAL374C, VAL377C, VAL409D, VAL6D, VAL71C, VAL8D, VAL95D
• C-F: ALA112F, ALA113C, ALA113F, ALA202C, ALA228C, ALA232C, ALA233C, ALA264F, ALA269C, ALA272F, ALA285C, ALA309F, ALA313F, ALA317F, ALA334C, ALA357F, ALA362C, ALA405C, ALA410C, ALA80C, ALA83C, ARG106C, ARG111F, ARG171C, ARG210C, ARG24F, ARG260F, ARG271C, ARG278C, ARG279C, ARG281F, ARG283C, ARG342F, ARG358F, ARG365C, ARG366F, ARG40C, ARG418C, ARG52F, ASN109C, ASN121F, ASN207C, ASN358C, ASN361C, ASP116C, ASP170C, ASP262C, ASP302F, ASP305F, ASP316F, ASP335F, ASP336C, ASP338F, ASP345F, ASP355F, ASP36C, ASP372F, ASP386F, ASP412C, ASP81C, GLN123F, GLN172C, GLN19F, GLN200C, GLN235C, GLN268F, GLN272C, GLN279F, GLN294F, GLN333C, GLN343F, GLN351F, GLN361F, GLN365F, GLN368F, GLN408C, GLN433C, GLN435C, GLN43F, GLN44F, GLN45F, GLU117F, GLU118F, GLU214C, GLU230C, GLU273F, GLU274F, GLU280F, GLU284C, GLU331C, GLU369F, GLU381F, GLU84C, GLY117C, GLY119C, GLY142F, GLY143F, GLY199C, GLY259F, GLY266F, GLY276F, GLY335C, GLY359F, GLY363C, GLY37C, GLY47F, GLY48F, GLY49F, GLY85C, HIS110F, HIS215C, HIS314F, ILE115C, ILE198C, ILE205C, ILE273C, ILE282F, ILE31C, ILE363F, ILE364C, ILE373F, ILE374F, ILE376F, ILE50F, LEU119F, LEU218C, LEU234C, LEU258F, LEU271F, LEU275C, LEU276C, LEU277C, LEU278F, LEU303F, LEU315F, LEU337F, LEU344F, LEU347F, LEU359C, LEU364F, LEU370F, LEU377F, LEU382F, LEU46F, LEU82C, LYS118C, LYS144F, LYS201C, LYS211C, LYS265C, LYS286F, LYS371F, LYS432C, LYS434C, MET136F, MET261F, MET275F, MET86C, PHE148F, PHE286C, PHE312F, PHE360C, PHE409C, PRO114C, PRO114F, PRO18F, PRO23F, PRO262F, PRO269F, PRO280C, PRO281C, PRO287C, PRO306F, PRO308F, PRO336F, PRO346F, PRO366C, PRO78C, SER115F, SER120F, SER122F, SER203C, SER206C, SER229C, SER231C, SER255F, SER263F, SER274C, SER284F, SER339F, SER33C, SER341F, SER35C, SER362F, SER383F, SER407C, SER411C, THR176C, THR204C, THR227C, THR270F, THR283F, THR304F, THR310F, THR311F, THR318F, THR332C, THR340F, THR357C, TYR116F, TYR267F, TYR26F, TYR354F, TYR436C, TYR79C, VAL107C, VAL108C, VAL208C, VAL209C, VAL223C, VAL225C, VAL22F, VAL25F, VAL265F, VAL268C, VAL277F, VAL319F, VAL320F, VAL32C, VAL348F, VAL34C, VAL38C, VAL42F, VAL51F
• C-G: ALA1G, ALA283G, ALA284G, ALA285C, ALA334C, ALA410C, ARG278C, ARG279C, ARG283C, ARG418C, ARG84G, ASN126G, ASP336C, ASP412C, ASP83G, GLN274G, GLU275G, GLU278G, GLU284C, GLU5G, GLY282C, GLY282G, GLY2G, GLY85G, ILE279G, LEU275C, LEU86G, LYS120G, LYS4G, MET23G, MET246G, PHE124G, PHE286C, PHE409C, PRO280C, PRO281C, SER119G, SER123G, SER281G, SER338C, SER411C, THR277G
• C-H: ALA115H, ALA117H, ALA119H, ALA122H, ALA124H, ALA126H, ALA334C, ALA404C, ALA405C, ALA410C, ALA416C, ARG129H, ARG418C, ASN358C, ASP412C, ASP414C, ASP415C, GLN116H, GLN127H, GLN408C, GLU120H, GLU132H, GLU356C, GLU402C, GLY335C, HIS104H, HIS109H, ILE105H, ILE125H, LEU121H, LEU359C, LEU403C, LEU413C, LYS123H, LYS419C, PHE406C, PHE409C, SER106H, SER107H, SER108H, SER118H, SER407C, SER411C, THR357C, THR417C, TYR114H
• D-G: ALA264D, ALA283G, ALA284G, ARG260D, ARG7G, ARG84G, ASP302D, GLU275G, GLU278G, GLY259D, GLY266D, GLY282G, ILE279G, ILE376D, LEU377D, LYS4G, MET261D, PRO262D, SER263D, SER281G, THR304D, TYR267D, VAL265D, VAL280G
• D-H: ALA115H, ALA117H, ALA119H, ALA122H, ALA375D, ASP111H, ASP113H, ASP372D, ASP380D, GLN116H, GLN368D, GLU120H, GLU369D, GLU381D, GLY110H, GLY378D, HIS109H, ILE373D, ILE374D, ILE376D, LEU121H, LEU370D, LEU377D, LEU382D, LYS123H, LYS371D, MET379D, SER106H, SER107H, SER108H, SER118H, TYR114H, VAL112H
• E-F: MET261E, PRO262F
• E-G: ALA240G, ALA264E, ALA270G, ALA283G, ALA284G, ALA28G, ALA300E, ALA309E, ALA375E, ARG260E, ARG268G, ARG7G, ASN176G, ASN265G, ASP251G, ASP301E, ASP302E, ASP305E, ASP372E, GLN261G, GLN269G, GLN274G, GLN35G, GLU24G, GLU275G, GLU278G, GLU381E, GLY259E, GLY266E, GLY282G, GLY378E, ILE175G, ILE272G, ILE279G, ILE373E, ILE376E, LEU262G, LEU276G, LEU303E, LEU377E, LYS21G, LYS247G, LYS266G, MET178G, MET243G, MET261E, MET31G, PHE174G, PRO262E, PRO299E, PRO306E, PRO308E, SER179G, SER263E, SER271G, SER281G, SER307E, THR177G, THR273G, THR277G, THR304E, TYR245E, TYR264G, TYR267E, TYR297E, VAL244G, VAL265E, VAL280G, VAL298E
• E-U: ASP380E, ASP380U, ASP436E, ASP436U, GLU381E, GLU381U, GLU384E, GLU384U, HIS437E, HIS437U
• E-W: ARG32W, ARG42W, ASP36W, GLU169E, GLU454E, HIS170E, LYS201W, LYS457E, LYS458E
• E-X: GLU408E, HIS5X
• F-G: ALA1G, ALA245G, ALA248G, ALA249G, ALA264F, ALA270G, ALA283G, ALA284G, ALA300F, ALA375F, ARG242G, ASN126G, ASN252G, ASN91G, ASN93G, ASP251G, ASP301F, ASP302F, ASP305F, ASP372F, ASP380F, ASP386F, CYS87G, GLN17G, GLN274G, GLU278G, GLU381F, GLU384F, GLU385F, GLY129G, GLY253G, GLY254G, GLY266F, GLY282G, GLY378F, GLY85G, GLY88G, GLY89G, ILE19G, ILE257G, ILE373F, ILE374F, ILE376F, ILE92G, LEU256G, LEU260G, LEU377F, LEU382F, LEU86G, LEU90G, LEU99G, LYS120G, LYS266G, LYS371F, LYS387F, LYS96G, LYS9G, MET23G, MET246G, MET261F, MET379F, PHE124G, PHE125G, PHE95G, PRO262F, PRO306F, SER123G, SER127G, SER255G, SER263F, SER281G, SER383F, THR16G, THR20G, THR250G, THR273G, THR277G, THR304F, TYR267F, VAL128G, VAL13G, VAL265F, VAL280G
• F-H: ALA122H, ALA124H, ALA126H, ALA137H, ALA375F, ARG129H, ARG323F, ARG394F, ARG398F, ASP301F, ASP372F, GLN127H, GLN324F, GLN365F, GLN368F, GLN397F, GLU132H, GLU369F, GLU381F, GLY378F, ILE125H, ILE131H, ILE325F, ILE373F, ILE374F, ILE376F, LEU121H, LEU128H, LEU133H, LEU328F, LEU370F, LEU377F, LEU382F, LYS135H, LYS136H, LYS371F, MET138H, MET379F, SER118H, SER322F, SER327F, THR134H, TYR114H, TYR367F, VAL130H, VAL390F
• F-J: ALA416J, ASP415J, GLU450F, GLU454F, LYS419J, LYS457F, VAL453F
• F-N: ALA456F, ALA456N, GLU454F, GLU454N, LEU459F, LEU459N, LYS455N, LYS457F, LYS457N, LYS458F, LYS458N, PRO439F
• G-H: ALA101H, ALA115G, ALA115H, ALA117H, ALA119H, ALA11G, ALA11H, ALA122H, ALA124H, ALA126H, ALA134G, ALA158G, ALA1G, ALA22G, ALA249G, ALA27G, ALA39G, ALA39H, ALA40G, ALA44H, ALA45G, ALA80H, ALA83H, ALA92H, ALA94H, ALA97H, ARG129H, ARG163G, ARG220G, ARG221G, ARG242G, ARG37G, ARG42G, ARG49G, ARG7G, ARG84G, ARG85H, ARG93H, ARG99H, ASN126G, ASN131G, ASN142G, ASN15G, ASN75H, ASP111H, ASP113H, ASP141G, ASP204G, ASP210G, ASP36G, ASP7H, ASP81H, ASP83G, ASP88H, ASP90H, CYS87G, GLN116H, GLN127H, GLN135G, GLN13H, GLN14G, GLN14H, GLN157G, GLN17G, GLN226G, GLN229G, GLN239G, GLN261G, GLN72H, GLN87H, GLU102H, GLU103H, GLU120H, GLU12H, GLU132H, GLU147G, GLU208G, GLU224G, GLU238G, GLU259G, GLU29H, GLU46G, GLU5G, GLU70H, GLU91H, GLU96H, GLY110H, GLY118G, GLY138G, GLY140G, GLY150G, GLY253G, GLY27H, GLY2G, GLY30H, GLY66H, GLY67H, GLY85G, GLY86H, HIS104H, HIS109H, HIS38H, HIS54G, ILE105H, ILE10G, ILE125H, ILE131H, ILE149G, ILE19G, ILE257G, ILE45H, ILE52G, ILE68H, ILE6G, ILE84H, LEU114G, LEU121H, LEU128H, LEU133H, LEU145G, LEU148G, LEU156G, LEU206G, LEU214G, LEU215G, LEU218G, LEU256G, LEU260G, LEU262G, LEU32H, LEU41H, LEU42H, LEU55G, LEU69H, LEU79H, LEU86G, LEU89H, LYS100H, LYS120G, LYS123H, LYS135H, LYS136H, LYS153G, LYS18G, LYS201G, LYS21G, LYS258G, LYS266G, LYS30G, LYS50G, LYS98H, LYS9G, MET116G, MET139G, MET155G, MET15H, MET23G, MET246G, MET38G, MET48G, MET95H, PHE124G, PHE125G, PRO143G, PRO151G, PRO209G, PRO211G, PRO40H, PRO43G, PRO73H, SER106H, SER107H, SER108H, SER10H, SER118H, SER119G, SER123G, SER127G, SER12G, SER144G, SER146G, SER202G, SER225G, SER255G, SER28H, SER29G, SER41G, SER8G, THR134H, THR137G, THR16G, THR20G, THR217G, THR250G, THR43H, THR47G, THR77H, THR82G, THR82H, TRP203G, TYR114H, TYR205G, TYR207G, TYR222G, TYR228G, TYR264G, TYR44G, VAL112H, VAL122G, VAL130H, VAL132G, VAL133G, VAL136G, VAL13G, VAL152G, VAL154G, VAL232G, VAL263G, VAL26G, VAL51G, VAL71H, VAL76H, VAL78H, VAL8H, VAL9H
• G-K: ALA509K, GLU61G
• G-O: ARG163G, ARG163O, ARG74G, ARG74O, ASN126O, ASN131G, ASN131O, ASP107G, ASP107O, ASP113G, ASP113O, ASP71G, CYS112G, CYS112O, GLN111G, GLN111O, GLY109G, GLY109O, GLY129G, GLY129O, GLY130G, GLY130O, LEU114G, LEU114O, LEU164G, LEU164O, LEU99G, LEU99O, LYS103G, LYS103O, LYS108G, LYS108O, LYS73G, LYS73O, MET102G, MET102O, PHE125G, PHE125O, SER127G, SER127O, THR106G, THR106O, TRP105G, TRP105O, VAL110G, VAL110O, VAL128G, VAL128O, VAL132G, VAL132O, VAL133G, VAL133O, VAL75G, VAL75O
• G-P: ALA101P, GLU102P, LYS73G
• G-U: ARG32G, ARG42G, ASP195G, ASP36G, ASP422U, GLU169U, GLU454U, HIS170U, LYS201G, LYS421U, LYS457U, LYS458U, SER171U
• H-O: ALA101H, GLU102H, LYS73O
• H-U: GLU408U, HIS5H
• I-J: ARG278J, PRO280I
• I-K: ARG278I, PRO280K
• I-L: ALA112L, ALA113L, ALA202I, ALA21L, ALA228I, ALA232I, ALA233I, ALA264L, ALA269I, ALA272L, ALA285I, ALA309L, ALA313L, ALA317L, ALA334I, ALA362I, ALA80I, ALA83I, ARG111L, ARG171I, ARG210I, ARG218L, ARG24L, ARG260L, ARG271I, ARG278I, ARG279I, ARG281L, ARG283I, ARG342L, ARG358L, ARG365I, ARG40I, ARG52L, ASN121L, ASN207I, ASN361I, ASP116I, ASP20L, ASP262I, ASP27L, ASP302L, ASP305L, ASP316L, ASP336I, ASP338L, ASP345L, ASP36I, ASP372L, ASP81I, GLN172I, GLN19L, GLN200I, GLN235I, GLN268L, GLN272I, GLN279L, GLN333I, GLN361L, GLN408I, GLN435I, GLN43L, GLN44L, GLN45L, GLU117L, GLU118L, GLU230I, GLU273L, GLU274L, GLU280L, GLU284I, GLU331I, GLU369L, GLU84I, GLY117I, GLY142L, GLY143L, GLY199I, GLY259L, GLY266L, GLY276L, GLY282I, GLY363I, GLY37I, GLY47L, GLY48L, GLY49L, GLY85I, HIS110L, HIS314L, ILE115I, ILE205I, ILE273I, ILE282L, ILE31I, ILE39I, ILE50L, LEU119L, LEU218I, LEU258L, LEU271L, LEU275I, LEU276I, LEU277I, LEU278L, LEU303L, LEU315L, LEU337L, LEU344L, LEU347L, LEU46L, LEU82I, LYS118I, LYS144L, LYS201I, LYS265I, LYS286L, LYS434I, MET261L, MET275L, MET86I, PHE148L, PHE17L, PHE286I, PHE312L, PHE360I, PHE409I, PRO114I, PRO114L, PRO18L, PRO23L, PRO262L, PRO269L, PRO280I, PRO281I, PRO306L, PRO308L, PRO346L, PRO74L, PRO78I, SER115L, SER120L, SER122L, SER203I, SER206I, SER229I, SER231I, SER255L, SER263L, SER274I, SER284L, SER307L, SER33I, SER341L, SER35I, THR204I, THR227I, THR270L, THR283L, THR304L, THR310L, THR311L, THR318L, THR340L, TYR116L, TYR267L, TYR26L, TYR354L, TYR436I, TYR79I, VAL107I, VAL108I, VAL208I, VAL209I, VAL223I, VAL225I, VAL22L, VAL25L, VAL265L, VAL268I, VAL277L, VAL32I, VAL34I, VAL38I, VAL42L, VAL51L
• I-M: ALA11M, ALA128I, ALA131I, ALA133I, ALA151M, ALA250M, ALA256M, ALA264M, ALA300M, ALA301I, ALA302I, ALA311I, ALA45I, ALA63I, ARG139I, ARG164I, ARG182M, ARG184M, ARG216M, ARG246M, ARG260M, ARG279I, ARG283I, ARG296I, ARG300I, ARG303I, ARG376I, ARG40I, ARG52M, ARG63M, ARG64M, ARG68I, ARG86M, ASN187M, ASN210M, ASN215M, ASN243M, ASN27I, ASN305I, ASN33M, ASN344I, ASN65I, ASP14M, ASP188M, ASP289I, ASP305M, ASP350I, ASP46I, ASP60M, ASP69I, ASP96M, CYS47I, CYS90I, GLN140I, GLN163I, GLN208M, GLN268M, GLN352I, GLN49I, GLN7M, GLU130I, GLU138I, GLU16M, GLU181M, GLU185M, GLU211M, GLU253M, GLU28I, GLU299I, GLU307I, GLU51I, GLU67I, GLY10M, GLY135I, GLY150M, GLY152M, GLY162I, GLY178M, GLY180M, GLY186M, GLY207M, GLY259M, GLY266M, GLY282I, GLY288I, GLY29I, GLY351I, GLY378I, GLY43I, GLY50I, GLY57M, GLY61M, GLY65M, GLY72I, GLY92I, HIS191M, HIS26I, HIS294I, HIS42I, ILE132I, ILE137I, ILE346I, ILE348I, ILE41I, ILE50M, ILE53I, ILE5M, ILE62I, ILE87M, ILE94I, ILE9M, LEU204M, LEU249M, LEU257M, LEU258M, LEU277I, LEU293I, LEU297I, LEU298I, LEU44I, LEU62M, LEU64I, LEU66I, LEU66M, LEU95I, LYS155M, LYS98M, MET209M, MET261M, MET48I, MET97M, PHE189M, PHE291I, PHE340I, PRO134I, PRO212M, PRO213M, PRO262M, PRO280I, PRO281I, PRO287I, PRO299M, PRO306M, PRO94M, SER141I, SER255M, SER295I, SER307M, SER338I, SER347I, SER58M, SER59M, SER70I, THR156M, THR183M, THR252M, THR343I, THR349I, THR91I, TYR190M, TYR206M, TYR245M, TYR267M, TYR270I, TYR292I, TYR297M, TYR308I, VAL12M, VAL136I, VAL13M, VAL142I, VAL153M, VAL254M, VAL265M, VAL290I, VAL345I, VAL374I, VAL377I, VAL6M, VAL71I, VAL8M, VAL95M
• I-O: ALA22O, ALA27O, ALA283O, ALA284O, ALA285I, ALA28O, ALA334I, ALA339I, ALA405I, ALA410I, ARG268O, ARG271I, ARG278I, ARG279I, ARG283I, ARG7O, ASN15O, ASN265O, ASP141O, ASP336I, ASP412I, ASP414I, GLN261O, GLN269O, GLN333I, GLN408I, GLU24O, GLU275O, GLU278O, GLU284I, GLU402I, GLY282I, GLY282O, GLY288I, GLY335I, ILE19O, ILE272O, ILE279O, LEU275I, LEU276O, LEU403I, LEU413I, LYS18O, LYS21O, LYS30O, LYS33O, MET23O, MET25O, PHE286I, PHE340I, PHE406I, PHE409I, PRO280I, PRO281I, PRO287I, SER271O, SER29O, SER338I, SER407I, SER411I, THR20O, THR273O, THR277O, THR343I, THR417I, TYR264O, VAL26O, VAL280O, VAL337I
• I-P: ALA115P, ALA117P, ALA119P, ALA410I, ASP111P, ASP113P, ASP412I, GLN116P, GLN408I, GLU120P, LEU121P, PHE409I, SER118P, SER407I, SER411I, TYR114P, VAL112P
• J-M: ALA112M, ALA113M, ALA140M, ALA177J, ALA202J, ALA21M, ALA228J, ALA232J, ALA233J, ALA264M, ALA269J, ALA272M, ALA285J, ALA309M, ALA313M, ALA317M, ALA334J, ALA362J, ALA80J, ALA83J, ARG106J, ARG171J, ARG210J, ARG218M, ARG24M, ARG260M, ARG271J, ARG278J, ARG279J, ARG281M, ARG283J, ARG342M, ARG358M, ARG365J, ARG40J, ARG52M, ARG59J, ASN109J, ASN121M, ASN207J, ASN361J, ASP116J, ASP20M, ASP262J, ASP27M, ASP302M, ASP305M, ASP316M, ASP336J, ASP345M, ASP36J, ASP81J, GLN123M, GLN172J, GLN19M, GLN200J, GLN235J, GLN268M, GLN272J, GLN279M, GLN333J, GLN343M, GLN361M, GLN435J, GLN43M, GLN44M, GLN45M, GLU117M, GLU214J, GLU230J, GLU273M, GLU274M, GLU280M, GLU284J, GLU331J, GLU84J, GLY117J, GLY142M, GLY143M, GLY174J, GLY199J, GLY259M, GLY266M, GLY276M, GLY335J, GLY363J, GLY37J, GLY47M, GLY48M, GLY49M, GLY85J, HIS110M, HIS215J, HIS314M, ILE115J, ILE205J, ILE273J, ILE282M, ILE31J, ILE364J, ILE39J, ILE50M, LEU119M, LEU218J, LEU234J, LEU258M, LEU271M, LEU275J, LEU276J, LEU277J, LEU278M, LEU303M, LEU315M, LEU337M, LEU347M, LEU46M, LEU82J, LYS118J, LYS141M, LYS144M, LYS175J, LYS201J, LYS211J, LYS265J, LYS286M, LYS432J, LYS434J, MET261M, MET275M, MET86J, PHE148M, PHE17M, PHE286J, PHE312M, PHE360J, PRO114M, PRO18M, PRO23M, PRO262M, PRO269M, PRO280J, PRO281J, PRO287J, PRO306M, PRO308M, PRO346M, PRO74M, PRO78J, SER115M, SER120M, SER122M, SER203J, SER206J, SER229J, SER231J, SER255M, SER263M, SER274J, SER284M, SER33J, SER341M, SER35J, THR173J, THR176J, THR204J, THR227J, THR270M, THR283M, THR304M, THR310M, THR311M, THR318M, THR332J, THR340M, TYR116M, TYR267M, TYR26M, TYR354M, TYR436J, TYR79J, VAL107J, VAL108J, VAL209J, VAL223J, VAL225J, VAL22M, VAL25M, VAL265M, VAL268J, VAL277M, VAL298M, VAL32J, VAL348M, VAL34J, VAL38J, VAL42M, VAL51M
• J-N: ALA11N, ALA128J, ALA131J, ALA133J, ALA151N, ALA250N, ALA256N, ALA264N, ALA285J, ALA300N, ALA301J, ALA302J, ALA311J, ALA326N, ALA339J, ALA380J, ALA381J, ALA398J, ALA407N, ALA416J, ALA45J, ALA63J, ARG139J, ARG161J, ARG164J, ARG182N, ARG184N, ARG216N, ARG246N, ARG250J, ARG260N, ARG278J, ARG279J, ARG283J, ARG296J, ARG300J, ARG303J, ARG323N, ARG376J, ARG394J, ARG394N, ARG398N, ARG40J, ARG52N, ARG63N, ARG64N, ARG68J, ARG86N, ARG93J, ASN158N, ASN187N, ASN210N, ASN215N, ASN243N, ASN27J, ASN305J, ASN33N, ASN344J, ASN35N, ASN65J, ASN89N, ASP14N, ASP188N, ASP289J, ASP301N, ASP302N, ASP305N, ASP336J, ASP350J, ASP46J, ASP60N, ASP69J, ASP96N, CYS47J, CYS90J, GLN140J, GLN163J, GLN208N, GLN324N, GLN352J, GLN399J, GLN420J, GLN441N, GLN49J, GLN7N, GLU130J, GLU138J, GLU181N, GLU185N, GLU192N, GLU211N, GLU253N, GLU284J, GLU299J, GLU307J, GLU402J, GLU408N, GLU440N, GLU51J, GLU67J, GLY10N, GLY135J, GLY149N, GLY150N, GLY152N, GLY154N, GLY162J, GLY178N, GLY180N, GLY186N, GLY207N, GLY214N, GLY259N, GLY266N, GLY282J, GLY288J, GLY329N, GLY34N, GLY351J, GLY371J, GLY378J, GLY379J, GLY391J, GLY392J, GLY412N, GLY43J, GLY50J, GLY57N, GLY61N, GLY65N, GLY72J, GLY92J, HIS191N, HIS294J, HIS42J, ILE132J, ILE137J, ILE157J, ILE330N, ILE346J, ILE348J, ILE372J, ILE41J, ILE50N, ILE53J, ILE5N, ILE62J, ILE87N, ILE94J, ILE9N, LEU166J, LEU204N, LEU249N, LEU257N, LEU277J, LEU293J, LEU297J, LEU298J, LEU303N, LEU328N, LEU403J, LEU413J, LEU44J, LEU459N, LEU46N, LEU62N, LEU64J, LEU66J, LEU66N, LEU95J, LYS155N, LYS387J, LYS419J, LYS455N, LYS458N, LYS98N, MET156J, MET209N, MET261N, MET445N, MET48J, MET88N, MET97N, PHE176N, PHE189N, PHE286J, PHE291J, PHE340J, PHE354J, PHE410N, PRO134J, PRO158J, PRO212N, PRO213N, PRO262N, PRO280J, PRO281J, PRO287J, PRO299N, PRO306N, PRO308N, PRO342J, PRO370J, PRO94N, SER141J, SER255N, SER263N, SER295J, SER307N, SER327N, SER338J, SER347J, SER373J, SER375J, SER390J, SER413N, SER58N, SER59N, SER70J, THR156N, THR183N, THR252N, THR304N, THR343J, THR349J, THR395J, THR411N, THR417J, THR91J, TYR190N, TYR206N, TYR245N, TYR267N, TYR292J, TYR297N, TYR308J, TYR331N, TYR444N, VAL12N, VAL136J, VAL13N, VAL142J, VAL153N, VAL157N, VAL205N, VAL254N, VAL265N, VAL290J, VAL298N, VAL337J, VAL341J, VAL345J, VAL374J, VAL377J, VAL406N, VAL409N, VAL6N, VAL71J, VAL8N, VAL95N
• J-O: ALA270O, ALA283O, ALA284O, ALA285J, ALA334J, ALA339J, ARG271J, ARG278J, ARG279J, ARG283J, ASP336J, GLN269O, GLN274O, GLN333J, GLU259O, GLU278O, GLU284J, GLY282J, GLY335J, LEU262O, LEU275J, LEU276O, LYS266O, PHE286J, PHE340J, PRO280J, PRO281J, SER281O, SER338J, THR273O, THR277O, VAL263O, VAL280O, VAL337J
• J-P: ASP336J, LYS135P, SER338J, VAL337J
• K-L: ALA11L, ALA131K, ALA133K, ALA151L, ALA250L, ALA256L, ALA25K, ALA264L, ALA285K, ALA300L, ALA301K, ALA302K, ALA326L, ALA339K, ALA375L, ALA380K, ALA381K, ALA396K, ALA398K, ALA410K, ALA416K, ALA45K, ALA55L, ALA63K, ARG139K, ARG161K, ARG164K, ARG182L, ARG184L, ARG216L, ARG246L, ARG260L, ARG278K, ARG279K, ARG283K, ARG296K, ARG300K, ARG303K, ARG323L, ARG376K, ARG394K, ARG394L, ARG398L, ARG401K, ARG418K, ARG52L, ARG63L, ARG64L, ARG68K, ARG86L, ARG93K, ASN187L, ASN210L, ASN215L, ASN243L, ASN27K, ASN305K, ASN33L, ASN344K, ASN35L, ASN65K, ASP143K, ASP14L, ASP188L, ASP289K, ASP301L, ASP302L, ASP305L, ASP336K, ASP350K, ASP372L, ASP380L, ASP412K, ASP414K, ASP415K, ASP46K, ASP60L, ASP69K, ASP96L, CYS47K, CYS90K, GLN140K, GLN163K, GLN208L, GLN324L, GLN352K, GLN368L, GLN399K, GLN420K, GLN49K, GLN7L, GLU130K, GLU138K, GLU16L, GLU181L, GLU185L, GLU192L, GLU211L, GLU253L, GLU284K, GLU299K, GLU381L, GLU402K, GLU408L, GLU51K, GLU67K, GLY10L, GLY135K, GLY149L, GLY150L, GLY152L, GLY154L, GLY162K, GLY180L, GLY186L, GLY214L, GLY259L, GLY266L, GLY282K, GLY288K, GLY29K, GLY329L, GLY34L, GLY351K, GLY371K, GLY378K, GLY378L, GLY379K, GLY391K, GLY412L, GLY43K, GLY50K, GLY57L, GLY61L, GLY65L, GLY72K, GLY92K, HIS191L, HIS26K, HIS294K, HIS42K, ILE132K, ILE137K, ILE325L, ILE330L, ILE346K, ILE348K, ILE372K, ILE373L, ILE374L, ILE376L, ILE41K, ILE50L, ILE5L, ILE87L, ILE94K, ILE9L, LEU204L, LEU249L, LEU257L, LEU258L, LEU277K, LEU293K, LEU297K, LEU298K, LEU328L, LEU377L, LEU397K, LEU403K, LEU413K, LEU44K, LEU62L, LEU64K, LEU66K, LEU66L, LYS155L, LYS371L, LYS387K, LYS98L, MET209L, MET261L, MET379L, MET48K, MET88L, MET97L, PHE189L, PHE286K, PHE291K, PHE340K, PHE354K, PHE406K, PHE409K, PHE410L, PRO134K, PRO212L, PRO213L, PRO262L, PRO280K, PRO281K, PRO287K, PRO299L, PRO306L, PRO342K, PRO370K, PRO94L, SER141K, SER255L, SER263L, SER274K, SER295K, SER327L, SER338K, SER347K, SER373K, SER375K, SER411K, SER58L, SER59L, SER70K, THR156L, THR183L, THR252L, THR343K, THR349K, THR395K, THR411L, THR417K, THR91K, TYR190L, TYR206L, TYR245L, TYR267L, TYR270K, TYR292K, TYR297L, TYR308K, TYR331L, TYR400K, TYR444L, VAL12L, VAL136K, VAL13L, VAL142K, VAL153L, VAL157L, VAL254L, VAL265L, VAL290K, VAL337K, VAL345K, VAL374K, VAL377K, VAL409L, VAL6L, VAL71K, VAL8L, VAL95L
• K-N: ALA112N, ALA113K, ALA113N, ALA202K, ALA228K, ALA232K, ALA233K, ALA256N, ALA264N, ALA269K, ALA272N, ALA285K, ALA309N, ALA313N, ALA317N, ALA334K, ALA357N, ALA362K, ALA405K, ALA410K, ALA80K, ALA83K, ARG106K, ARG111N, ARG171K, ARG210K, ARG24N, ARG260N, ARG271K, ARG278K, ARG279K, ARG281N, ARG283K, ARG342N, ARG358N, ARG365K, ARG366N, ARG40K, ARG418K, ARG52N, ASN109K, ASN121N, ASN207K, ASN358K, ASN361K, ASP116K, ASP262K, ASP302N, ASP305N, ASP316N, ASP335N, ASP336K, ASP338N, ASP345N, ASP355N, ASP36K, ASP372N, ASP386N, ASP412K, ASP81K, GLN123N, GLN172K, GLN19N, GLN200K, GLN235K, GLN268N, GLN272K, GLN279N, GLN294N, GLN333K, GLN343N, GLN351N, GLN361N, GLN365N, GLN368N, GLN408K, GLN425K, GLN433K, GLN435K, GLN43N, GLN44N, GLN45N, GLU117N, GLU118N, GLU214K, GLU230K, GLU273N, GLU274N, GLU280N, GLU284K, GLU331K, GLU369N, GLU381N, GLU84K, GLY117K, GLY119K, GLY142N, GLY143N, GLY199K, GLY259N, GLY266N, GLY276N, GLY335K, GLY359N, GLY363K, GLY37K, GLY47N, GLY48N, GLY49N, GLY85K, HIS110N, HIS215K, HIS314N, ILE115K, ILE198K, ILE205K, ILE273K, ILE282N, ILE31K, ILE363N, ILE364K, ILE373N, ILE374N, ILE376N, ILE50N, LEU119N, LEU234K, LEU258N, LEU271N, LEU275K, LEU276K, LEU277K, LEU278N, LEU303N, LEU315N, LEU337N, LEU344N, LEU347N, LEU359K, LEU364N, LEU370N, LEU377N, LEU382N, LEU46N, LEU82K, LYS118K, LYS144N, LYS201K, LYS211K, LYS265K, LYS286N, LYS371N, LYS432K, LYS434K, MET136N, MET261N, MET275N, MET86K, PHE148N, PHE286K, PHE312N, PHE360K, PHE409K, PRO114K, PRO114N, PRO18N, PRO23N, PRO262N, PRO269N, PRO280K, PRO281K, PRO306N, PRO308N, PRO336N, PRO346N, PRO366K, PRO78K, SER115N, SER120N, SER122N, SER203K, SER206K, SER229K, SER231K, SER255N, SER263N, SER274K, SER284N, SER339N, SER33K, SER341N, SER35K, SER362N, SER383N, SER407K, SER411K, THR176K, THR204K, THR227K, THR270N, THR283N, THR304N, THR310N, THR311N, THR318N, THR332K, THR340N, THR357K, TYR116N, TYR267N, TYR26N, TYR354N, TYR436K, TYR79K, VAL107K, VAL108K, VAL208K, VAL209K, VAL223K, VAL224K, VAL225K, VAL22N, VAL25N, VAL265N, VAL268K, VAL277N, VAL319N, VAL320N, VAL32K, VAL348N, VAL34K, VAL38K, VAL42N, VAL51N
• K-O: ALA1O, ALA283O, ALA284O, ALA285K, ALA334K, ALA410K, ARG278K, ARG279K, ARG283K, ARG84O, ASN126O, ASP336K, ASP412K, ASP83O, GLN274O, GLU275O, GLU278O, GLU284K, GLU5O, GLY282K, GLY282O, GLY2O, GLY85O, ILE279O, LEU275K, LEU86O, LYS120O, LYS4O, MET23O, MET246O, PHE286K, PHE409K, PRO280K, PRO281K, SER119O, SER123O, SER281O, SER338K, SER411K
• K-P: ALA115P, ALA117P, ALA119P, ALA122P, ALA124P, ALA126P, ALA334K, ALA404K, ALA405K, ALA410K, ALA416K, ARG129P, ARG418K, ASN358K, ASP412K, ASP414K, ASP415K, GLN116P, GLN127P, GLN408K, GLU120P, GLU132P, GLU356K, GLU402K, GLY335K, HIS104P, HIS109P, ILE105P, ILE125P, LEU121P, LEU359K, LEU403K, LEU413K, LYS123P, LYS419K, PHE406K, PHE409K, SER106P, SER107P, SER108P, SER118P, SER407K, SER411K, THR357K, TYR114P
• L-O: ALA264L, ALA283O, ALA284O, ARG260L, ARG7O, ARG84O, ASP302L, GLU275O, GLU278O, GLY259L, GLY266L, GLY282O, ILE279O, ILE376L, LEU377L, LYS4O, MET261L, PRO262L, SER263L, SER281O, THR304L, TYR267L, VAL265L, VAL280O
• L-P: ALA115P, ALA117P, ALA119P, ALA122P, ALA375L, ASP111P, ASP113P, ASP372L, ASP380L, GLN116P, GLN368L, GLU120P, GLU369L, GLU381L, GLY110P, GLY378L, HIS109P, ILE373L, ILE374L, ILE376L, LEU121P, LEU370L, LEU377L, LEU382L, LYS123P, LYS371L, MET379L, SER106P, SER107P, SER108P, SER118P, TYR114P, VAL112P
• M-N: MET261M, PRO262N
• M-O: ALA240O, ALA256M, ALA264M, ALA270O, ALA283O, ALA284O, ALA28O, ALA300M, ALA309M, ARG260M, ARG268O, ASN176O, ASN265O, ASP251O, ASP301M, ASP302M, ASP305M, ASP372M, GLN261O, GLN269O, GLN274O, GLU24O, GLU275O, GLU278O, GLU381M, GLY259M, GLY266M, GLY282O, GLY378M, ILE175O, ILE272O, ILE279O, ILE373M, ILE376M, LEU262O, LEU276O, LEU303M, LEU377M, LYS21O, LYS247O, LYS266O, MET178O, MET243O, MET261M, MET31O, PHE174O, PRO262M, PRO299M, PRO306M, PRO308M, SER179O, SER263M, SER271O, SER281O, SER307M, THR177O, THR273O, THR277O, THR304M, TYR245M, TYR264O, TYR267M, TYR297M, VAL244O, VAL265M, VAL280O, VAL298M
• M-c: ASP380M, ASP380c, ASP436M, ASP436c, GLU381M, GLU381c, GLU384M, GLU384c, HIS437M, HIS437c
• M-e: ARG42e, ASP36e, GLU169M, GLU454M, HIS170M, LYS201e, LYS457M, LYS458M
• M-f: GLU408M, HIS5f
• N-O: ALA1O, ALA245O, ALA248O, ALA249O, ALA264N, ALA283O, ALA284O, ALA300N, ALA375N, ARG242O, ARG84O, ASN126O, ASN252O, ASN91O, ASN93O, ASP251O, ASP301N, ASP302N, ASP305N, ASP372N, ASP380N, CYS87O, GLN17O, GLN274O, GLU278O, GLU381N, GLU384N, GLU385N, GLY129O, GLY253O, GLY254O, GLY266N, GLY282O, GLY378N, GLY85O, GLY88O, GLY89O, ILE19O, ILE257O, ILE373N, ILE374N, ILE376N, ILE92O, LEU256O, LEU260O, LEU377N, LEU382N, LEU388N, LEU86O, LEU90O, LEU99O, LYS120O, LYS266O, LYS387N, LYS96O, LYS9O, MET23O, MET246O, MET261N, MET379N, PHE124O, PHE125O, PHE95O, PRO262N, PRO306N, SER123O, SER127O, SER255O, SER263N, SER281O, SER383N, THR16O, THR20O, THR250O, THR273O, THR277O, THR304N, VAL128O, VAL13O, VAL265N, VAL280O
• N-P: ALA122P, ALA124P, ALA126P, ALA137P, ALA375N, ARG129P, ARG323N, ARG394N, ARG398N, ASP301N, ASP372N, GLN127P, GLN324N, GLN365N, GLN368N, GLN397N, GLU132P, GLU369N, GLU381N, GLY378N, ILE125P, ILE131P, ILE325N, ILE330N, ILE373N, ILE374N, ILE376N, LEU121P, LEU128P, LEU133P, LEU328N, LEU370N, LEU377N, LYS135P, LYS136P, LYS371N, MET138P, MET379N, SER118P, SER322N, SER327N, THR134P, TYR114P, TYR367N, VAL130P, VAL390N
• N-R: ARG235N, ASP236N, ASP478R, GLU124N, HIS479R
• O-P: ALA101P, ALA115O, ALA115P, ALA117P, ALA119P, ALA11O, ALA11P, ALA122P, ALA124P, ALA126P, ALA134O, ALA1O, ALA213O, ALA22O, ALA249O, ALA27O, ALA39O, ALA39P, ALA40O, ALA44P, ALA45O, ALA80P, ALA83P, ALA92P, ALA94P, ALA97P, ARG129P, ARG163O, ARG220O, ARG221O, ARG242O, ARG37O, ARG42O, ARG49O, ARG7O, ARG84O, ARG85P, ARG93P, ARG99P, ASN126O, ASN131O, ASN142O, ASN15O, ASN75P, ASP111P, ASP113P, ASP141O, ASP204O, ASP210O, ASP36O, ASP7P, ASP81P, ASP83O, ASP88P, ASP90P, CYS87O, GLN116P, GLN127P, GLN135O, GLN13P, GLN14O, GLN14P, GLN157O, GLN17O, GLN226O, GLN229O, GLN239O, GLN261O, GLN72P, GLN87P, GLU102P, GLU103P, GLU120P, GLU12P, GLU132P, GLU147O, GLU208O, GLU224O, GLU238O, GLU259O, GLU29P, GLU46O, GLU5O, GLU70P, GLU91P, GLU96P, GLY110P, GLY118O, GLY138O, GLY140O, GLY150O, GLY253O, GLY27P, GLY2O, GLY30P, GLY66P, GLY67P, GLY85O, GLY86P, HIS104P, HIS109P, HIS38P, HIS54O, ILE105P, ILE10O, ILE125P, ILE131P, ILE149O, ILE19O, ILE257O, ILE45P, ILE52O, ILE68P, ILE6O, ILE84P, LEU114O, LEU121P, LEU128P, LEU133P, LEU145O, LEU148O, LEU156O, LEU206O, LEU214O, LEU215O, LEU218O, LEU256O, LEU260O, LEU262O, LEU32P, LEU41P, LEU42P, LEU55O, LEU69P, LEU79P, LEU86O, LEU89P, LYS100P, LYS120O, LYS123P, LYS135P, LYS136P, LYS153O, LYS18O, LYS201O, LYS21O, LYS258O, LYS266O, LYS30O, LYS50O, LYS98P, LYS9O, MET116O, MET139O, MET155O, MET15P, MET23O, MET246O, MET38O, MET48O, MET95P, PHE124O, PRO143O, PRO151O, PRO209O, PRO211O, PRO40P, PRO43O, PRO73P, SER106P, SER107P, SER108P, SER10P, SER118P, SER119O, SER123O, SER127O, SER12O, SER144O, SER146O, SER202O, SER225O, SER255O, SER28P, SER29O, SER41O, SER8O, THR134P, THR137O, THR16O, THR20O, THR217O, THR43P, THR47O, THR77P, THR82O, THR82P, TRP203O, TYR114P, TYR205O, TYR207O, TYR222O, TYR228O, TYR264O, TYR44O, VAL112P, VAL122O, VAL130P, VAL132O, VAL133O, VAL136O, VAL13O, VAL152O, VAL154O, VAL232O, VAL263O, VAL26O, VAL51O, VAL71P, VAL76P, VAL78P, VAL8P, VAL9P
• O-c: ARG42O, ASP195O, ASP36O, ASP422c, GLU169c, GLU454c, HIS170c, LYS201O, LYS421c, LYS457c, LYS458c
• P-c: GLU408c, HIS5P
• Q-T: ALA202Q, ARG210Q, ARG24T, ARG260T, ARG278Q, ASP20T, ASP316T, ASP36Q, ASP81Q, GLN333Q, GLN45T, GLU230Q, GLU273T, GLU280T, GLU84Q, GLY259T, GLY49T, HIS314T, LYS144T, LYS201Q, SER120T, THR304T, VAL34Q
• Q-U: ALA133Q, ARG139Q, ARG164Q, ARG182U, ARG184U, ARG376Q, ARG63U, ARG64U, ARG68Q, ASN210U, ASP14U, ASP289Q, ASP350Q, ASP46Q, ASP60U, GLN49Q, GLU130Q, GLU16U, GLU185U, GLU211U, GLU253U, GLU299Q, GLU51Q, GLU67Q, GLY43Q, GLY61U, ILE348Q, LEU44Q, LEU62U, LEU66Q, THR183U, VAL8U
• Q-W: ARG7W, ASP141W, ASP336Q, ASP412Q, GLU275W, GLU284Q, LYS30W, LYS33W
• Q-X: ASP113X, ASP412Q
• R-U: ALA202R, ARG24U, ARG260U, ARG278R, ASP116R, ASP20U, ASP27U, ASP316U, ASP36R, ASP81R, GLN45U, GLU117U, GLU230R, GLU273U, GLU280U, GLU84R, GLY49U, HIS314U, LYS144U, LYS201R, VAL34R
• R-V: ARG139R, ARG164R, ARG182V, ARG184V, ARG283R, ARG376R, ARG63V, ARG64V, ARG68R, ASP14V, ASP289R, ASP302V, ASP305V, ASP350R, ASP46R, ASP60V, ASP69R, GLN49R, GLU130R, GLU185V, GLU211V, GLU253V, GLU299R, GLU51R, GLU67R, GLY379R, GLY43R, GLY61V, ILE348R, LEU66R, MET209V, PRO299V, SER295R, SER347R, THR183V, VAL409V, VAL8V
• R-W: ASP336R, LYS266W
• R-X: ASP336R, LYS135X
• S-T: ALA375T, ARG139S, ARG164S, ARG182T, ARG184T, ARG376S, ARG63T, ARG64T, ARG68S, ASP14T, ASP188T, ASP289S, ASP350S, ASP380T, ASP414S, ASP46S, ASP60T, ASP69S, GLN49S, GLU130S, GLU16T, GLU185T, GLU253T, GLU299S, GLU402S, GLU51S, GLU67S, GLY43S, GLY61T, LEU62T, LEU66S, LYS371T, SER347S, THR183T, VAL8T
• S-V: ALA202S, ARG171S, ARG24V, ARG260V, ARG271S, ARG278S, ARG342V, ARG358V, ARG365S, ASP116S, ASP316V, ASP338V, ASP345V, ASP36S, ASP81S, GLN44V, GLN45V, GLU117V, GLU230S, GLU273V, GLU274V, GLU280V, GLU84S, GLY259V, GLY363S, GLY48V, GLY49V, HIS314V, LYS144V, LYS201S, LYS211S, SER263V, VAL34S
• S-W: ARG283S, ASP412S, GLU275W, GLU278W, GLU284S, LYS120W
• S-X: ASP415S, GLU402S, HIS104X, LYS123X, SER106X
• T-W: ASP302T, LYS4W
• T-X: ASP372T, GLU120X, GLU381T, HIS109X, LYS123X
• U-W: ARG268W, ASP302U, ASP305U, ASP372U, LYS247W
• V-W: ALA375V, ASN252W, GLU381V, LEU86W
• V-X: ARG129X, ASP301V, ASP372V, GLU132X, GLU369V, ILE131X, LYS135X
• W-X: ALA44X, ALA97X, ARG129X, ARG220W, ARG221W, ARG37W, ARG84W, ARG85X, ARG93X, ASP111X, ASP113X, ASP141W, ASP81X, ASP83W, ASP90X, GLN135W, GLU120X, GLU12X, GLU147W, GLU208W, GLU224W, GLU259W, GLU29X, GLU5W, GLU70X, GLU91X, GLU96X, GLY85W, HIS109X, HIS54W, LEU145W, LEU206W, LYS135X, LYS136X, LYS153W, LYS18W, LYS30W, LYS50W, LYS98X, LYS9W, PRO40X, TYR114X, TYR205W
• Y-b: ALA202Y, ARG210Y, ARG24b, ARG260b, ARG278Y, ASP20b, ASP316b, ASP36Y, ASP81Y, GLN333Y, GLN44b, GLN45b, GLU117b, GLU230Y, GLU273b, GLU280b, GLU84Y, GLY259b, GLY49b, HIS314b, LYS201Y, SER120b, THR304b, VAL34Y
• Y-c: ALA133Y, ARG139Y, ARG164Y, ARG182c, ARG184c, ARG376Y, ARG63c, ARG64c, ARG68Y, ASN210c, ASP14c, ASP188c, ASP289Y, ASP350Y, ASP46Y, ASP60c, ASP69Y, ASP96c, GLN49Y, GLU130Y, GLU138Y, GLU16c, GLU185c, GLU211c, GLU253c, GLU299Y, GLU51Y, GLU67Y, GLY61c, HIS191c, ILE348Y, LEU44Y, LEU62c, LEU66Y, THR183c, VAL8c
• Y-e: ARG7e, ASP141e, ASP336Y, ASP412Y, GLN408Y, GLU275e, GLU284Y, LYS18e, LYS30e, LYS33e
• Y-f: ASP113f, ASP412Y, SER411Y
• Z-c: ALA202Z, ARG24c, ARG260c, ARG278Z, ASP116Z, ASP20c, ASP27c, ASP316c, ASP36Z, ASP81Z, GLN45c, GLU117c, GLU230Z, GLU273c, GLU280c, GLU84Z, GLY259c, GLY49c, HIS314c, LYS144c, LYS201Z, VAL34Z
• Z-d: ARG139Z, ARG164Z, ARG182d, ARG184d, ARG283Z, ARG376Z, ARG63d, ARG64d, ARG68Z, ASP14d, ASP289Z, ASP302d, ASP305d, ASP350Z, ASP46Z, ASP60d, GLN49Z, GLU130Z, GLU185d, GLU211d, GLU253d, GLU299Z, GLU51Z, GLU67Z, GLY379Z, GLY43Z, GLY61d, ILE348Z, LEU66Z, SER347Z, THR183d, VAL409d, VAL8d
• Z-e: ASP336Z, LYS266e
• Z-f: ASP336Z, LYS135f
• a-b: ALA375b, ARG139a, ARG164a, ARG182b, ARG184b, ARG376a, ARG63b, ARG64b, ARG68a, ASP14b, ASP188b, ASP289a, ASP350a, ASP380b, ASP414a, ASP46a, ASP60b, ASP69a, GLN49a, GLU130a, GLU16b, GLU185b, GLU253b, GLU299a, GLU402a, GLU51a, GLU67a, LEU62b, LEU66a, LYS371b, MET209b, SER295a, SER347a, THR183b, VAL8b
• a-d: ALA362a, ARG171a, ARG24d, ARG260d, ARG271a, ARG278a, ARG342d, ARG358d, ARG365a, ASP116a, ASP316d, ASP338d, ASP36a, ASP81a, GLN172a, GLN44d, GLN45d, GLU117d, GLU230a, GLU273d, GLU274d, GLU280d, GLU84a, GLY259d, GLY48d, GLY49d, HIS314d, LYS144d, LYS201a, SER263d, SER362d, THR340d, VAL34a
• a-e: ARG283a, ASP412a, GLU275e, GLU278e, GLU284a, LYS120e
• a-f: ASP412a, ASP415a, GLU402a, HIS104f, HIS109f, LYS123f, SER106f
• b-e: ASP302b, LYS4e
• b-f: ASP111f, ASP372b, GLU120f, GLU381b, HIS109f, LYS123f
• c-e: ARG268e, ASP302c, ASP305c, ASP372c, LYS247e
• d-e: GLU381d, LEU86e
• d-f: ARG129f, ASP301d, ASP372d, GLU132f, GLU369d, ILE131f, LYS135f
• e-f: ALA44f, ALA97f, ARG129f, ARG220e, ARG221e, ARG37e, ARG84e, ARG85f, ARG93f, ASP111f, ASP113f, ASP141e, ASP81f, ASP83e, ASP90f, GLN135e, GLU120f, GLU12f, GLU147e, GLU208e, GLU224e, GLU259e, GLU29f, GLU5e, GLU70f, GLU91f, GLU96f, GLY85e, HIS109f, HIS54e, LEU145e, LEU206e, LYS135f, LYS136f, LYS153e, LYS18e, LYS30e, LYS50e, LYS98f, LYS9e, PRO40f, TYR114f