3O6O

crystal structure of the n-terminal domain of an hsp90 from trypanosoma brucei, tb10.26.1080 in the presence of an the inhibitor biib021

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 110
  • Norm. En. per Res.: -1.7496
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.5347	13.8434	-193.762	-192.4534	110	5	4	8186	0	23	19

Interface residues

• A-B: ALA106A, ALA106B, ALA109B, ALA86A, ALA86B, ALA96A, ALA96B, ARG31A, ARG31B, ARG45A, ARG45B, ARG97A, ARG97B, ASN139A, ASN139B, ASN51A, ASN51B, ASN90A, ASN90B, ASN91A, ASN91B, ASP112A, ASP39A, ASP39B, ASP42A, ASP42B, ASP87A, ASP87B, CYS41A, CYS41B, GLN118A, GLN118B, GLN47A, GLN47B, GLU105A, GLU105B, GLU108B, GLU141A, GLU141B, GLU197A, GLU197B, GLY110B, GLY111B, GLY117A, GLY120A, GLY120B, GLY200A, GLY200B, GLY82A, GLY82B, GLY93A, GLY93B, GLY99A, GLY99B, HIS195A, HIS195B, ILE116A, ILE199A, ILE199B, ILE44B, ILE81A, ILE81B, ILE95A, ILE95B, LEU107B, LEU49A, LEU49B, LEU61B, LEU88A, LEU88B, LEU92A, LEU92B, LYS101A, LYS101B, LYS193A, LYS43A, LYS43B, MET104B, MET115A, MET115B, MET83A, MET83B, PHE103A, PHE103B, PHE119A, PHE119B, PHE198A, PHE198B, SER102A, SER102B, SER196A, SER196B, SER35A, SER38A, SER38B, SER48A, SER48B, SER98A, SER98B, THR100A, THR50A, THR50B, THR84A, THR84B, THR94A, THR94B, TYR201A, TYR201B, TYR46A, TYR46B