3O4X

crystal structure of complex between amino and carboxy terminal fragments of mdia1

• Total interactions analyzed: 28
• Total true interactions: 18
• Strongest Interaction:
  • Chains: E-H
  • Int. Res.: 254
  • Norm. En. per Res.: -4.5209
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-47.6086	-146.9076	-243.262	-437.7781	190	43	52	40266	11	100	90
A-E	-24.0759	-87.9098	-375.748	-487.7337	140	16	7	15980	7	97	45
A-G	-8.5598	-1.9493	-27.6143	-38.1234	47	3	0	1244	2	26	14
A-F	-14.0386	-84.8366	-71.1645	-170.0397	49	1	0	2964	4	33	26
B-C	-51.3367	-105.3288	-185.551	-342.2165	190	54	54	40099	9	96	92
B-E	-9.2105	-97.6143	-74.2982	-181.123	48	1	0	2949	5	31	25
B-H	0.0	-6.7	-33.537	-40.237	44	2	0	1401	4	25	15
B-F	-20.3863	-108.4157	-376.938	-505.74	142	12	9	16453	5	97	45
C-E	-3.5434	-0.9475	-24.9006	-29.3915	39	0	0	1034	2	24	13
C-H	-6.0452	-87.6451	-68.0667	-161.7571	44	1	0	2789	3	30	25
C-G	-47.0334	-88.8984	-354.441	-490.3728	131	14	10	15141	7	83	34
D-H	-10.3335	-94.9217	-298.627	-403.8822	132	14	7	13157	4	76	30
D-G	-13.2255	-84.6256	-75.8823	-173.7334	48	3	0	3048	3	31	26
D-F	0.0	-4.9002	-28.3392	-33.2394	46	1	0	1285	1	25	13
E-H	-80.5606	118.5832	-1186.34	-1148.3175	254	34	42	46000	0	42	69
E-G	-6.6601	39.2203	-117.891	-85.3308	108	17	0	6372	1	44	47
H-F	-19.946	28.3687	-119.06	-110.6373	98	9	0	5988	1	36	35
G-F	-87.5283	89.0678	-1114.67	-1113.1305	253	43	40	44484	3	39	71

Interface residues

• A-D: ALA397A, ALA397D, ALA417A, ALA417D, ARG322A, ARG326A, ARG326D, ARG331A, ARG331D, ARG370A, ARG370D, ARG375A, ARG375D, ARG412A, ARG412D, ARG418A, ARG418D, ARG446A, ARG446D, ASN390A, ASN390D, ASN413A, ASN413D, ASP320A, ASP320D, ASP366A, ASP366D, ASP372A, ASP372D, ASP373A, ASP373D, ASP379A, ASP379D, ASP380A, ASP380D, ASP394A, ASP394D, ASP414A, ASP414D, ASP440A, ASP440D, ASP442A, ASP442D, ASP451A, ASP451D, CYS428A, CYS428D, CYS445A, CYS445D, GLN386A, GLN386D, GLN406A, GLN406D, GLN420A, GLN420D, GLN431A, GLN431D, GLN449A, GLN449D, GLU328A, GLU328D, GLU377A, GLU377D, GLU383A, GLU383D, GLU398A, GLU398D, GLU416A, GLU416D, GLU426A, GLU426D, GLU427A, GLU427D, GLY369A, GLY369D, GLY382A, GLY382D, GLY438D, HIS324A, HIS324D, HIS400A, HIS400D, HIS407A, HIS407D, HIS435A, HIS435D, HIS447A, HIS447D, ILE325A, ILE325D, ILE374A, ILE374D, ILE387A, ILE387D, ILE388A, ILE388D, ILE404A, ILE404D, ILE425A, ILE425D, ILE432A, ILE432D, ILE450A, ILE450D, ILE452A, ILE452D, LEU319A, LEU319D, LEU367A, LEU367D, LEU371A, LEU371D, LEU389A, LEU389D, LEU402A, LEU402D, LEU405A, LEU405D, LEU408A, LEU408D, LEU409A, LEU409D, LEU410A, LEU410D, LEU424A, LEU424D, LEU434A, LEU434D, LEU448A, LEU448D, LYS368A, LYS368D, LYS393A, LYS393D, LYS396A, LYS396D, LYS423A, LYS423D, LYS444A, LYS444D, MET376A, MET376D, MET378A, MET378D, PHE321A, PHE321D, PHE381A, PHE381D, PHE385A, PHE385D, PHE401A, PHE401D, PHE443A, PHE443D, PRO399A, PRO399D, PRO419A, PRO419D, PRO441A, PRO441D, SER327A, SER327D, SER395A, SER395D, SER403A, SER403D, SER430A, SER430D, THR391A, THR391D, THR439A, THR439D, TYR415A, TYR415D, TYR421A, TYR421D, TYR422A, TYR422D, VAL323A, VAL323D, VAL384A, VAL384D, VAL392A, VAL392D, VAL411A, VAL411D, VAL429A, VAL429D, VAL433A, VAL433D
• A-E: ALA1148E, ALA1151E, ALA1155E, ALA1174E, ALA1188E, ALA1193E, ALA1194E, ALA214A, ALA250A, ALA251A, ALA256A, ALA311A, ALA316A, ARG1146E, ARG1147E, ARG1159E, ARG1166E, ARG1196E, ARG1197E, ARG322A, ARG370A, ARG375A, ASN1173E, ASN164A, ASN165A, ASN166A, ASN217A, ASN218A, ASN267A, ASN310A, ASP1171E, ASP1177E, ASP1183E, ASP249A, ASP265A, ASP348A, ASP361A, ASP363A, ASP366A, ASP372A, ASP373A, ASP379A, ASP380A, CYS258A, CYS354A, GLN1163E, GLN1164E, GLN1168E, GLN1190E, GLN172A, GLN262A, GLN307A, GLN352A, GLN359A, GLU1140E, GLU1143E, GLU1158E, GLU1167E, GLU1175E, GLU1178E, GLU1187E, GLU264A, GLU317A, GLU318A, GLU347A, GLU358A, GLU362A, GLU377A, GLU383A, GLY1176E, GLY1180E, GLY1192E, GLY221A, GLY304A, GLY369A, ILE1170E, ILE222A, ILE248A, ILE259A, ILE309A, ILE313A, LEU1150E, LEU1160E, LEU1169E, LEU1185E, LEU1186E, LEU1189E, LEU163A, LEU212A, LEU226A, LEU235A, LEU253A, LEU254A, LEU257A, LEU260A, LEU306A, LEU308A, LEU312A, LYS1144E, LYS1149E, LYS1152E, LYS1154E, LYS1162E, LYS1198E, LYS213A, LYS219A, LYS223A, LYS252A, MET1145E, MET1172E, MET1182E, MET216A, MET225A, MET266A, MET349A, MET376A, MET378A, PHE1195E, PHE215A, PHE220A, PHE356A, PHE365A, PRO167A, PRO261A, PRO263A, PRO315A, SER1184E, SER1191E, SER169A, SER255A, THR1141E, THR1179E, THR224A, THR314A, VAL1181E, VAL168A, VAL171A, VAL303A, VAL351A, VAL355A
• A-G: ALA804G, ARG1032G, ARG269A, ARG285A, ARG418A, ARG763G, ARG764G, ARG991G, ASN1123G, ASN413A, ASN766G, ASP1120G, ASP265A, ASP379A, ASP414A, ASP992G, CYS354A, CYS988G, GLN262A, GLN805G, GLN998G, GLU264A, GLU268A, GLU272A, GLU276A, GLU279A, GLU318A, GLU358A, GLU416A, LEU987G, LEU990G, LYS769G, LYS838G, LYS989G, LYS994G, MET1127G, PHE1124G, PHE321A, PHE986G, SER768G, SER985G, THR275A, THR806G, TRP767G, TYR415A, VAL351A, VAL355A
• A-F: ALA273A, ALA278A, ALA397A, ARG1125F, ARG269A, ARG277A, ARG285A, ARG975F, ARG991F, ASN1123F, ASN1126F, ASN390A, ASN976F, ASP1120F, ASP394A, CYS988F, GLN1130F, GLU1116F, GLU1134F, GLU229A, GLU272A, GLU276A, GLU279A, GLU398A, GLY973F, HIS1122F, HIS324A, LEU1112F, LEU1129F, LEU233A, LEU271A, LEU389A, LYS393A, LYS396A, LYS989F, MET1119F, MET1127F, MET274A, MET280A, PHE1117F, PHE1124F, PHE1128F, PRO399A, SER395A, SER974F, SER985F, THR275A, THR391A, VAL392A
• B-C: ALA397B, ALA397C, ALA417B, ALA417C, ARG322B, ARG322C, ARG326B, ARG326C, ARG331B, ARG331C, ARG370B, ARG370C, ARG375B, ARG375C, ARG412B, ARG412C, ARG418B, ARG418C, ARG446B, ARG446C, ASN390B, ASN390C, ASN413B, ASN413C, ASP320B, ASP320C, ASP366B, ASP366C, ASP372B, ASP372C, ASP373B, ASP373C, ASP379B, ASP379C, ASP380B, ASP380C, ASP394B, ASP394C, ASP414B, ASP414C, ASP440B, ASP440C, ASP442B, ASP442C, ASP451B, ASP451C, CYS428B, CYS428C, CYS445B, CYS445C, GLN386B, GLN386C, GLN406B, GLN406C, GLN420B, GLN420C, GLN431B, GLN431C, GLN449B, GLN449C, GLU328B, GLU328C, GLU377B, GLU377C, GLU383B, GLU383C, GLU398B, GLU398C, GLU416B, GLU416C, GLU426B, GLU426C, GLU427B, GLU427C, GLY369B, GLY369C, GLY382B, GLY382C, GLY438B, HIS324B, HIS324C, HIS400B, HIS400C, HIS407B, HIS407C, HIS435B, HIS435C, HIS447B, HIS447C, ILE325B, ILE325C, ILE374B, ILE374C, ILE387B, ILE387C, ILE388B, ILE388C, ILE404B, ILE404C, ILE425B, ILE425C, ILE432B, ILE432C, ILE450B, ILE450C, ILE452B, LEU319B, LEU319C, LEU367B, LEU367C, LEU371B, LEU371C, LEU389B, LEU389C, LEU402B, LEU402C, LEU405B, LEU405C, LEU408B, LEU408C, LEU409B, LEU409C, LEU410B, LEU410C, LEU424B, LEU424C, LEU434B, LEU434C, LEU448B, LEU448C, LYS368B, LYS368C, LYS393B, LYS393C, LYS396B, LYS396C, LYS423B, LYS423C, LYS444B, LYS444C, MET376B, MET376C, MET378B, MET378C, PHE321B, PHE321C, PHE381B, PHE381C, PHE385B, PHE385C, PHE401B, PHE401C, PHE443B, PHE443C, PRO399B, PRO399C, PRO419B, PRO419C, PRO441B, PRO441C, SER327B, SER327C, SER395B, SER395C, SER403B, SER403C, SER430B, SER430C, THR391B, THR391C, THR439B, THR439C, TYR415B, TYR415C, TYR421B, TYR421C, TYR422B, TYR422C, VAL323B, VAL323C, VAL384B, VAL384C, VAL392B, VAL392C, VAL411B, VAL411C, VAL429B, VAL429C, VAL433B, VAL433C
• B-E: ALA273B, ALA278B, ALA397B, ARG1125E, ARG269B, ARG277B, ARG285B, ARG975E, ARG991E, ASN1123E, ASN1126E, ASN390B, ASN976E, ASP1120E, ASP394B, CYS988E, GLN1130E, GLN998E, GLU1116E, GLU229B, GLU272B, GLU276B, GLU279B, GLU318B, GLU398B, GLY973E, HIS1122E, LEU1112E, LEU1129E, LEU233B, LEU271B, LYS393B, LYS396B, LYS989E, MET1119E, MET1127E, MET274B, MET280B, PHE1117E, PHE1124E, PHE1128E, PRO399B, SER395B, SER974E, SER985E, THR275B, THR391B, VAL392B
• B-H: ALA804H, ARG269B, ARG285B, ARG418B, ARG763H, ARG764H, ARG991H, ASN1123H, ASN413B, ASN766H, ASP1120H, ASP265B, ASP414B, ASP992H, CYS354B, CYS988H, GLN262B, GLN761H, GLN805H, GLU264B, GLU268B, GLU272B, GLU276B, GLU279B, GLU318B, GLU358B, GLU416B, LEU987H, LEU990H, LYS769H, LYS838H, LYS989H, LYS994H, MET1127H, PHE1124H, PHE986H, SER768H, SER985H, THR275B, THR806H, TRP767H, TYR415B, VAL351B, VAL355B
• B-F: ALA1148F, ALA1151F, ALA1155F, ALA1174F, ALA1188F, ALA1193F, ALA1194F, ALA214B, ALA250B, ALA251B, ALA256B, ALA300B, ALA311B, ALA316B, ARG1146F, ARG1147F, ARG1159F, ARG1166F, ARG1196F, ARG1197F, ARG322B, ARG375B, ASN1173F, ASN164B, ASN165B, ASN166B, ASN217B, ASN218B, ASN267B, ASN310B, ASN346B, ASP1171F, ASP1177F, ASP1183F, ASP249B, ASP265B, ASP348B, ASP361B, ASP363B, ASP366B, ASP372B, ASP373B, ASP379B, ASP380B, CYS258B, CYS354B, GLN1163F, GLN1164F, GLN1168F, GLN1190F, GLN172B, GLN262B, GLN307B, GLN352B, GLN359B, GLU1140F, GLU1143F, GLU1158F, GLU1167F, GLU1175F, GLU1178F, GLU1187F, GLU264B, GLU317B, GLU318B, GLU347B, GLU358B, GLU362B, GLU377B, GLU383B, GLY1176F, GLY1180F, GLY1192F, GLY221B, GLY304B, GLY369B, ILE1170F, ILE222B, ILE248B, ILE259B, ILE309B, ILE313B, ILE374B, LEU1150F, LEU1160F, LEU1169F, LEU1185F, LEU1186F, LEU1189F, LEU163B, LEU212B, LEU226B, LEU235B, LEU253B, LEU254B, LEU257B, LEU260B, LEU306B, LEU308B, LEU312B, LYS1144F, LYS1149F, LYS1152F, LYS1154F, LYS1162F, LYS1165F, LYS1198F, LYS213B, LYS219B, LYS223B, LYS252B, MET1145F, MET1172F, MET1182F, MET216B, MET225B, MET266B, MET349B, MET376B, MET378B, PHE1195F, PHE215B, PHE220B, PHE356B, PHE365B, PRO167B, PRO261B, PRO263B, PRO315B, SER1184F, SER1191F, SER169B, SER255B, THR1141F, THR1179F, THR314B, VAL1181F, VAL168B, VAL171B, VAL303B, VAL351B, VAL355B
• C-E: ARG1032E, ARG269C, ARG418C, ARG764E, ARG991E, ASN1123E, ASN413C, ASN766E, ASP1120E, ASP379C, ASP414C, ASP774E, ASP992E, CYS988E, GLN998E, GLU264C, GLU268C, GLU272C, GLU276C, GLU279C, GLU282C, GLU358C, GLU416C, LEU987E, LEU990E, LYS769E, LYS838E, LYS989E, LYS994E, MET1127E, MET280C, PHE986E, SER768E, SER985E, THR275C, THR806E, TRP767E, TYR415C, VAL771E
• C-H: ALA273C, ALA278C, ALA397C, ARG1125H, ARG277C, ARG285C, ARG975H, ARG991H, ASN1123H, ASN1126H, ASN390C, ASN976H, ASP1120H, ASP394C, CYS988H, GLN1130H, GLU1116H, GLU229C, GLU272C, GLU276C, GLU279C, GLU398C, GLY973H, HIS1122H, LEU1112H, LEU233C, LEU271C, LYS393C, LYS396C, LYS989H, MET1119H, MET1127H, MET274C, MET280C, PHE1117H, PHE1124H, PHE1128H, PRO399C, SER395C, SER974H, SER985H, THR275C, THR391C, VAL392C
• C-G: ALA1148G, ALA1151G, ALA1174G, ALA1188G, ALA1193G, ALA1194G, ALA214C, ALA251C, ALA256C, ALA311C, ALA316C, ARG1146G, ARG1147G, ARG1159G, ARG1166G, ARG1196G, ARG1197G, ARG322C, ARG375C, ASN1173G, ASN164C, ASN165C, ASN166C, ASN217C, ASN218C, ASN267C, ASN310C, ASN346C, ASP1171G, ASP1177G, ASP1183G, ASP249C, ASP265C, ASP348C, ASP366C, ASP373C, ASP379C, ASP380C, CYS258C, CYS354C, GLN1163G, GLN1164G, GLN1168G, GLN1190G, GLN172C, GLN262C, GLN307C, GLN352C, GLN359C, GLU1140G, GLU1143G, GLU1158G, GLU1167G, GLU1175G, GLU1178G, GLU1187G, GLU264C, GLU317C, GLU318C, GLU347C, GLU358C, GLU362C, GLU377C, GLU383C, GLY1176G, GLY1180G, GLY1192G, GLY221C, GLY304C, ILE1170G, ILE222C, ILE248C, ILE259C, ILE309C, ILE313C, LEU1160G, LEU1169G, LEU1185G, LEU1186G, LEU1189G, LEU163C, LEU212C, LEU226C, LEU235C, LEU253C, LEU254C, LEU257C, LEU260C, LEU306C, LEU308C, LEU312C, LYS1144G, LYS1154G, LYS1162G, LYS1165G, LYS1198G, LYS213C, LYS219C, LYS223C, LYS252C, MET1145G, MET1172G, MET1182G, MET216C, MET225C, MET266C, MET349C, MET376C, MET378C, PHE1195G, PHE215C, PHE220C, PHE356C, PHE365C, PRO167C, PRO261C, PRO263C, PRO315C, SER1184G, SER1191G, SER169C, SER255C, THR1179G, THR224C, THR314C, VAL1181G, VAL168C, VAL171C, VAL303C, VAL351C, VAL355C
• D-H: ALA1148H, ALA1151H, ALA1174H, ALA1188H, ALA1193H, ALA1194H, ALA214D, ALA251D, ALA256D, ALA300D, ALA311D, ALA316D, ARG1147H, ARG1159H, ARG1166H, ARG1196H, ARG1197H, ARG322D, ARG375D, ASN164D, ASN165D, ASN166D, ASN217D, ASN218D, ASN267D, ASN310D, ASN346D, ASP1171H, ASP1177H, ASP1183H, ASP249D, ASP265D, ASP348D, ASP366D, ASP372D, ASP373D, ASP379D, ASP380D, CYS258D, CYS354D, GLN1163H, GLN1164H, GLN1168H, GLN1190H, GLN172D, GLN262D, GLN307D, GLN352D, GLN359D, GLU1140H, GLU1143H, GLU1158H, GLU1167H, GLU1175H, GLU1178H, GLU1187H, GLU264D, GLU317D, GLU318D, GLU347D, GLU358D, GLU362D, GLU377D, GLU383D, GLY1176H, GLY1180H, GLY1192H, GLY221D, GLY304D, ILE1170H, ILE222D, ILE248D, ILE259D, ILE309D, ILE313D, LEU1160H, LEU1169H, LEU1185H, LEU1186H, LEU1189H, LEU163D, LEU212D, LEU226D, LEU235D, LEU253D, LEU254D, LEU257D, LEU260D, LEU306D, LEU308D, LEU312D, LYS1144H, LYS1149H, LYS1154H, LYS1162H, LYS1165H, LYS1198H, LYS213D, LYS219D, LYS223D, LYS252D, MET1145H, MET1172H, MET1182H, MET216D, MET225D, MET266D, MET349D, MET376D, MET378D, PHE1195H, PHE215D, PHE220D, PHE356D, PHE365D, PRO167D, PRO261D, PRO263D, PRO315D, SER1184H, SER1191H, SER169D, SER255D, THR1179H, THR314D, TRP170D, VAL1181H, VAL168D, VAL171D, VAL303D, VAL351D, VAL355D
• D-G: ALA273D, ALA278D, ALA397D, ARG1125G, ARG269D, ARG277D, ARG285D, ARG975G, ARG991G, ASN1123G, ASN1126G, ASN390D, ASN976G, ASP1120G, ASP394D, CYS988G, GLN1130G, GLU1115G, GLU1116G, GLU229D, GLU272D, GLU276D, GLU279D, GLU398D, GLY973G, HIS1122G, HIS324D, LEU1112G, LEU1129G, LEU233D, LEU271D, LYS393D, LYS396D, LYS989G, MET1119G, MET1127G, MET274D, MET280D, PHE1117G, PHE1124G, PHE1128G, PRO399D, SER395D, SER974G, SER985G, THR275D, THR391D, VAL392D
• D-F: ALA804F, ARG269D, ARG285D, ARG418D, ARG763F, ARG764F, ARG991F, ASN1123F, ASN413D, ASN766F, ASP1120F, ASP265D, ASP414D, ASP774F, ASP992F, CYS988F, GLN262D, GLN805F, GLN998F, GLU229D, GLU264D, GLU268D, GLU272D, GLU276D, GLU279D, GLU282D, GLU318D, GLU358D, GLU416D, LEU987F, LEU990F, LYS769F, LYS838F, LYS989F, LYS994F, MET1127F, MET280D, PHE986F, SER768F, SER985F, THR275D, THR806F, TRP767F, TYR415D, VAL755F, VAL771F
• E-H: ALA772E, ALA772H, ALA796E, ALA796H, ALA801E, ALA801H, ALA804E, ALA804H, ALA972E, ALA972H, ALA977E, ALA977H, ALA979E, ALA979H, ALA996E, ALA996H, ARG763E, ARG763H, ARG764E, ARG764H, ARG788E, ARG788H, ARG951E, ARG951H, ARG975E, ARG975H, ARG991H, ASN1012E, ASN1012H, ASN766E, ASN766H, ASN791E, ASN791H, ASN792E, ASN792H, ASN955E, ASN955H, ASN968E, ASN968H, ASN971E, ASN971H, ASN976E, ASN976H, ASN983E, ASN983H, ASP1013E, ASP1013H, ASP1103E, ASP1103H, ASP1108E, ASP1108H, ASP774E, ASP774H, ASP778E, ASP778H, ASP787E, ASP787H, ASP992E, ASP992H, ASP997E, ASP997H, CYS1010E, CYS1010H, CYS779E, CYS779H, GLN761E, GLN761H, GLN777H, GLN805E, GLN805H, GLN998E, GLN998H, GLU1008E, GLU1016E, GLU1016H, GLU1100E, GLU1100H, GLU759E, GLU759H, GLU773E, GLU773H, GLU786E, GLU786H, GLU790E, GLU790H, GLU793E, GLU793H, GLU954E, GLU954H, GLU961E, GLU961H, GLY1102E, GLY1102H, GLY967E, GLY967H, GLY973E, GLY973H, GLY978E, GLY978H, GLY981E, GLY981H, HIS1004E, HIS1004H, HIS1014E, HIS1014H, ILE984E, ILE984H, LEU1002E, LEU1002H, LEU1003E, LEU1003H, LEU1006E, LEU1006H, LEU1009E, LEU1009H, LEU1101E, LEU1101H, LEU750E, LEU750H, LEU762E, LEU762H, LEU775E, LEU775H, LEU794E, LEU794H, LEU798E, LEU798H, LEU800E, LEU800H, LEU959E, LEU959H, LEU960E, LEU960H, LEU962E, LEU962H, LEU964E, LEU964H, LEU965E, LEU965H, LEU987E, LEU987H, LEU990E, LEU990H, LYS753E, LYS753H, LYS754E, LYS754H, LYS757E, LYS757H, LYS769E, LYS769H, LYS783E, LYS783H, LYS785E, LYS785H, LYS797E, LYS797H, LYS989E, LYS989H, LYS994E, LYS994H, LYS999E, LYS999H, MET1000E, MET1000H, MET970E, MET970H, PHE1005E, PHE1005H, PHE1105E, PHE1105H, PHE1107E, PHE1107H, PHE748H, PHE770E, PHE770H, PHE780E, PHE780H, PHE789E, PHE789H, PHE795E, PHE795H, PHE802E, PHE802H, PHE956E, PHE956H, PHE980E, PHE980H, PHE982E, PHE982H, PHE986E, PHE986H, PRO747E, PRO747H, PRO752E, PRO752H, PRO758E, PRO758H, PRO765E, PRO765H, SER768E, SER768H, SER776E, SER776H, SER803E, SER803H, SER953E, SER953H, SER957E, SER957H, SER958E, SER958H, SER974E, SER974H, SER985E, SER985H, SER995E, SER995H, THR1001E, THR1001H, THR751E, THR751H, THR782E, THR782H, THR799E, THR799H, THR963E, THR963H, THR993E, THR993H, TRP767E, TRP767H, TRP781E, TRP781H, TYR1104E, TYR1104H, TYR756E, TYR756H, TYR969E, TYR969H, VAL1017E, VAL1017H, VAL1106E, VAL1106H, VAL755E, VAL755H, VAL760E, VAL760H, VAL771E, VAL771H, VAL784E, VAL784H, VAL966E, VAL966H
• E-G: ALA1025E, ALA1025G, ALA1193E, ALA1193G, ALA1194E, ALA840E, ALA840G, ALA945E, ALA945G, ARG1032G, ARG1166E, ARG1166G, ARG1196E, ARG1196G, ARG1197E, ARG1197G, ASN842E, ASN842G, ASN876E, ASN876G, ASP1022E, ASP1022G, ASP836E, ASP836G, GLN1136E, GLN1163E, GLN1164E, GLN1164G, GLN1168E, GLN1168G, GLN841E, GLN841G, GLN875G, GLN880E, GLN880G, GLU1011E, GLU1011G, GLU1016E, GLU1016G, GLU1023E, GLU1023G, GLU1028G, GLU1158E, GLU1158G, GLU1161E, GLU1161G, GLU1167E, GLU1167G, GLU1175G, GLU949E, GLU949G, GLY1192E, GLY1192G, GLY848E, GLY848G, HIS1026E, HIS1026G, ILE845E, ILE845G, LEU1018E, LEU1018G, LEU1024E, LEU1024G, LEU1160E, LEU1160G, LEU1169E, LEU1169G, LEU843E, LEU843G, LYS1019E, LYS1019G, LYS1029E, LYS1029G, LYS1133E, LYS1133G, LYS1154E, LYS1157E, LYS1157G, LYS1162E, LYS1162G, LYS1165E, LYS1165G, LYS1198E, LYS1198G, LYS828E, LYS838E, LYS838G, LYS879E, LYS879G, LYS952G, PHE1195E, PHE846E, PHE846G, PHE850G, PRO1015E, PRO1015G, PRO1021E, SER1191E, SER837E, SER837G, SER844E, SER844G, SER849E, SER849G, SER872G, THR839E, THR839G, VAL941G
• H-F: ALA1025F, ALA1025H, ALA1174F, ALA1193F, ALA1193H, ALA840F, ALA840H, ALA945H, ARG1032H, ARG1166F, ARG1166H, ARG1196F, ARG1196H, ARG1197F, ARG1197H, ASN842F, ASN842H, ASN876F, ASN876H, ASP1022F, ASP1022H, ASP1171F, ASP836F, ASP836H, GLN1136F, GLN1163F, GLN1163H, GLN1164F, GLN1164H, GLN1168F, GLN1168H, GLN841F, GLN841H, GLN875H, GLN880F, GLN880H, GLU1011F, GLU1023H, GLU1140F, GLU1158F, GLU1161F, GLU1161H, GLU1167F, GLU1167H, GLU1175F, GLU949F, GLU949H, GLY1176F, GLY1192F, GLY848F, GLY848H, HIS1026F, HIS1026H, ILE845F, ILE845H, LEU1018F, LEU1024H, LEU1160F, LEU1160H, LEU1169F, LEU1169H, LEU843F, LEU843H, LYS1019F, LYS1019H, LYS1029F, LYS1029H, LYS1154F, LYS1157F, LYS1157H, LYS1162F, LYS1162H, LYS1165F, LYS1165H, LYS1198F, LYS1198H, LYS828H, LYS838F, LYS838H, LYS879F, LYS879H, PHE1195F, PHE1195H, PHE846F, PHE846H, PRO1015F, PRO1015H, SER1191F, SER837F, SER837H, SER844F, SER844H, SER849F, SER849H, SER872F, SER872H, THR839F, THR839H
• G-F: ALA772F, ALA772G, ALA796F, ALA796G, ALA801F, ALA801G, ALA804F, ALA804G, ALA972F, ALA972G, ALA977F, ALA977G, ALA979F, ALA979G, ALA996F, ALA996G, ARG763F, ARG763G, ARG764F, ARG764G, ARG788F, ARG788G, ARG951F, ARG951G, ARG975F, ARG975G, ARG991F, ASN1012F, ASN1012G, ASN766F, ASN766G, ASN791F, ASN791G, ASN792F, ASN792G, ASN955F, ASN955G, ASN968F, ASN968G, ASN971F, ASN971G, ASN976F, ASN976G, ASN983F, ASN983G, ASP1013F, ASP1013G, ASP1103F, ASP1103G, ASP1108F, ASP1108G, ASP774F, ASP774G, ASP778F, ASP778G, ASP787F, ASP787G, ASP992F, ASP992G, ASP997F, ASP997G, CYS1010F, CYS1010G, CYS779F, CYS779G, GLN761F, GLN761G, GLN777G, GLN805F, GLN805G, GLN998F, GLN998G, GLU1008G, GLU1016F, GLU1016G, GLU1100F, GLU1100G, GLU759F, GLU759G, GLU773F, GLU773G, GLU786F, GLU786G, GLU790F, GLU790G, GLU793F, GLU793G, GLU954F, GLU954G, GLU961F, GLU961G, GLY1102F, GLY1102G, GLY967F, GLY967G, GLY973F, GLY973G, GLY978F, GLY978G, GLY981F, GLY981G, HIS1004F, HIS1004G, HIS1014F, HIS1014G, ILE984F, ILE984G, LEU1002F, LEU1002G, LEU1003F, LEU1003G, LEU1006F, LEU1006G, LEU1009F, LEU1009G, LEU1101F, LEU1101G, LEU750F, LEU750G, LEU762F, LEU762G, LEU775F, LEU775G, LEU794F, LEU794G, LEU798F, LEU798G, LEU800F, LEU800G, LEU959F, LEU959G, LEU960F, LEU960G, LEU962F, LEU962G, LEU964F, LEU964G, LEU965F, LEU965G, LEU987F, LEU987G, LEU990F, LEU990G, LYS753F, LYS753G, LYS754F, LYS754G, LYS757F, LYS757G, LYS769F, LYS769G, LYS783F, LYS783G, LYS785F, LYS785G, LYS797F, LYS797G, LYS989F, LYS989G, LYS994F, LYS994G, LYS999F, LYS999G, MET1000F, MET1000G, MET970F, MET970G, PHE1005F, PHE1005G, PHE1105F, PHE1105G, PHE1107F, PHE1107G, PHE770F, PHE770G, PHE780F, PHE780G, PHE789F, PHE789G, PHE795F, PHE795G, PHE802F, PHE802G, PHE956F, PHE956G, PHE980F, PHE980G, PHE982F, PHE982G, PHE986F, PHE986G, PRO747F, PRO747G, PRO752F, PRO752G, PRO758F, PRO758G, PRO765F, PRO765G, SER768F, SER768G, SER776F, SER776G, SER803F, SER803G, SER953F, SER953G, SER957F, SER957G, SER958F, SER958G, SER974F, SER974G, SER985F, SER985G, SER995F, SER995G, THR1001F, THR1001G, THR751F, THR751G, THR782F, THR782G, THR799F, THR799G, THR963F, THR963G, THR993F, THR993G, TRP767F, TRP767G, TRP781F, TRP781G, TYR1104F, TYR1104G, TYR756F, TYR756G, TYR969F, TYR969G, VAL1017F, VAL1017G, VAL1106F, VAL1106G, VAL755F, VAL755G, VAL760F, VAL760G, VAL771F, VAL771G, VAL784F, VAL784G, VAL966F, VAL966G