3O3Q

crystal structure of "l44f/m67i/l73v/a103g/deletion 104- 106/f108y/v109l/l111i/c117v/r119g/deletion 120-122" mutant form of human acidic fibroblast growth factor

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 58
  • Norm. En. per Res.: -4.5255
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.7598	-22.327	-108.513	-162.5998	53	4	1	4563	0	14	11
A-C	-62.8521	-29.4619	-170.166	-262.4799	58	6	0	5794	2	22	12
A-D	-37.5808	7.5269	-173.762	-203.8159	70	9	0	6497	4	19	29
B-C	0.0	3.6783	-1.625	2.0533	10	0	0	277	0	12	10
C-D	-16.352	1.7008	-12.7796	-27.4308	19	1	0	859	0	8	7

Interface residues

• A-B: ARG24A, ARG35B, ARG37B, ASN18B, ASN80A, ASN92B, ASP28A, ASP36A, ASP36B, ASP39A, ASP39B, CYS16B, GLN40A, GLN63A, GLN77A, GLU60A, GLY19B, GLY20B, GLY29A, GLY62A, GLY75A, HIS21B, HIS41A, HIS93B, ILE25A, ILE42B, LEU131B, LEU133B, LEU135B, LEU13B, LEU14B, LEU26A, LYS128B, LYS57A, PHE22B, PRO134B, PRO136B, PRO27A, SER17B, SER38A, SER38B, SER58A, SER76A, THR30A, THR34B, THR61A, THR78A, TYR15B, TYR64A, TYR74A, TYR94B, VAL137B, VAL31A
• A-C: ALA129C, ALA48A, ARG88C, ASN80A, ASP68C, ASP70C, CYS83A, GLN127C, GLN45A, GLN63A, GLN77A, GLU49A, GLU53A, GLU81A, GLU82A, GLY103C, GLY110C, GLY119C, GLY126C, GLY62A, GLY71C, HIS102C, HIS124C, ILE130C, ILE56A, ILE67C, ILE98C, LEU46A, LEU72C, LEU84A, LEU86C, LYS100A, LYS100C, LYS101A, LYS101C, LYS10A, LYS112C, LYS118C, LYS57A, PRO79A, SER116C, SER47A, SER50A, SER58A, SER76A, SER99C, THR123C, THR59A, THR61A, THR69C, THR78A, TRP107C, TYR108C, TYR125C, TYR55A, TYR64A, VAL51A, VAL54A
• A-D: ARG35D, ARG37D, ARG88A, ASN18D, ASN92A, ASN92D, ASP140D, ASP36D, ASP68A, ASP70A, CYS16D, GLN127A, GLU49A, GLU53A, GLU82A, GLU87A, GLU90A, GLU90D, GLU91A, GLU91D, GLY103A, GLY126A, GLY19D, GLY20D, GLY52A, GLY71A, HIS102A, HIS124A, HIS21D, HIS93D, ILE130A, ILE98A, LEU131A, LEU131D, LEU133D, LEU135D, LEU13D, LEU72A, LEU84A, LEU86A, LEU89A, LEU89D, LYS100A, LYS101A, LYS10D, LYS113D, LYS128D, LYS12D, PHE132D, PHE22D, PHE85A, PRO134D, PRO136D, SER138D, SER139D, SER17D, SER38D, SER50A, SER99A, THR123A, THR34D, THR69A, THR96A, TRP107A, TYR108A, TYR125A, TYR15D, TYR94D, VAL137D, VAL51A
• B-C: ARG35B, ASN114B, ASP36B, GLY19B, HIS102C, HIS21B, LEU86C, LYS100C, LYS101C, LYS113B
• C-D: ALA129C, ASN114C, ASN18C, ASN92D, GLN127C, GLU90D, GLU91D, GLY126C, HIS124C, HIS93D, ILE130C, LEU89D, LYS112C, LYS113C, LYS118C, LYS128C, SER116C, THR123C, TYR125C