3O35

crystal structure of trim24 phd-bromo complexed with h3(23-31)k27ac peptide

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 48
  • Norm. En. per Res.: -2.4517
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.7815	7.091	-103.993	-117.6835	48	8	3	4385	0	8	11
A-E	0.0	-5.5005	-17.5059	-23.0064	17	3	0	1125	0	5	1
B-E	0.0	0.0	-0.8332	-0.8332	11	0	0	170	0	0	0

Interface residues

• A-B: ALA830A, ALA923A, ALA987A, ALA989A, ASN834A, ASN988A, ASP934B, CYS829A, CYS832A, CYS917A, GLN833A, GLN925A, GLU919A, GLU978B, GLU985A, GLY835A, GLY990A, HIS849A, HIS918A, ILE938B, ILE939B, LEU915A, LEU922A, LEU930B, LEU945A, LEU993A, LYS937B, LYS940B, LYS992A, MET920A, PHE914A, PHE924A, PHE979B, PRO927B, PRO929B, PRO933B, PRO942B, SER921A, SER984A, THR931B, TRP828A, TYR916A, TYR935B, TYR936B, VAL831A, VAL928B, VAL932B, VAL986A
• A-E: ALA25E, ALA29E, ARG26E, ASN980A, ASP934A, GLU981A, GLU985A, ILE938A, LYS937A, PHE979A, PRO933A, SER28E, SER984A, THR931A, TYR935A, VAL932A, VAL986A
• B-E: ALA29E, ARG26E, ARG951B, ASP944B, LYS950B, MET943B, PRO927B, PRO942B, SER28E, THR947B, TYR936B