3O10

crystal structure of the hepn domain from human sacsin

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 130
  • Norm. En. per Res.: -5.938
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-102.8231	-67.2948	-502.176	-672.294	126	19	2	18301	10	45	45
A-D	-16.8821	-9.6819	-42.1793	-68.7433	37	6	0	2087	0	12	8
B-C	0.0	0.0	-0.0547	-0.0547	6	0	0	20	0	2	2
B-D	-7.8124	-2.7754	-60.7723	-71.3601	40	4	3	2646	0	6	8
C-D	-108.514	-133.0107	-530.415	-771.9397	130	24	3	18950	15	47	46

Interface residues

• A-B: ALA4447A, ALA4454A, ALA4454B, ALA4456A, ALA4456B, ALA4460A, ALA4460B, ALA4461A, ALA4461B, ALA4469A, ALA4469B, ALA4487A, ALA4487B, ARG4448A, ARG4448B, ARG4449A, ARG4449B, ARG4452A, ARG4452B, ARG4455A, ARG4455B, ARG4462A, ARG4462B, ARG4537A, ARG4537B, ARG4551A, ARG4551B, ASN4443A, ASN4443B, ASN4457A, ASN4457B, ASN4463A, ASN4463B, ASN4468A, ASN4468B, ASN4470A, ASN4470B, ASN4549A, ASN4549B, ASP4464A, ASP4464B, ASP4497B, ASP4499B, ASP4540A, ASP4540B, ASP4550A, ASP4550B, CYS4477A, CYS4477B, GLN4453A, GLN4453B, GLN4546A, GLN4546B, GLU4446A, GLU4446B, GLU4471A, GLU4471B, HIS4466A, HIS4466B, ILE4486A, ILE4486B, ILE4547A, ILE4547B, LEU4451A, LEU4451B, LEU4465A, LEU4465B, LEU4479A, LEU4479B, LEU4483A, LEU4483B, LEU4534A, LEU4534B, LEU4541A, LEU4541B, LEU4542A, LEU4542B, LYS4467A, LYS4467B, LYS4476A, LYS4476B, LYS4482A, LYS4482B, LYS4498A, LYS4498B, LYS4535B, PHE4458A, PHE4458B, PHE4475A, PHE4475B, PHE4544A, PHE4544B, PHE4552B, PRO4502B, PRO4539A, PRO4539B, PRO4543A, PRO4543B, PRO4545A, PRO4545B, PRO4548A, PRO4548B, SER4459A, SER4459B, SER4480A, SER4480B, SER4496A, SER4496B, SER4533A, SER4533B, THR4536A, THR4536B, TRP4450A, TRP4450B, TRP4472A, TRP4472B, TYR4478A, TYR4478B, TYR4490A, TYR4490B, TYR4538A, TYR4538B, VAL4445A, VAL4445B, VAL4473A, VAL4473B
• A-D: ALA4447A, ALA4491A, ALA4504D, ALA4528D, ARG4449A, ARG4493A, ASN4443A, ASN4521D, ASP4522D, GLN4507D, GLN4514D, GLU4446A, GLU4510D, GLU4511D, GLU4517D, GLY4439A, GLY4442A, GLY4494A, GLY4518D, GLY4530D, HIS4524D, LEU4516D, LEU4519D, LEU4526D, LYS4495A, PRO4444A, SER4440A, SER4496A, THR4503D, THR4520D, THR4525D, TRP4450A, TYR4490A, TYR4529D, VAL4441A, VAL4445A, VAL4523D
• B-C: ALA4528B, ARG4449C, ASN4443C, GLN4507B, GLU4446C, HIS4524B
• B-D: ALA4528B, ALA4528D, ARG4551B, ARG4551D, ARG4559D, ASN4521B, ASP4532B, ASP4540B, GLN4546B, GLN4546D, GLU4527B, GLU4527D, GLY4530B, GLY4530D, HIS4524B, HIS4524D, LEU4526B, LEU4526D, LEU4541B, LEU4541D, LEU4542B, LEU4542D, LYS4535B, LYS4535D, PHE4544B, PHE4544D, PHE4552D, PRO4539B, PRO4543B, PRO4543D, PRO4545B, PRO4545D, THR4525B, THR4525D, TYR4529B, TYR4529D, VAL4531B, VAL4531D, VAL4556D, VAL4560D
• C-D: ALA4447C, ALA4454C, ALA4454D, ALA4456C, ALA4456D, ALA4460C, ALA4460D, ALA4461C, ALA4461D, ALA4469C, ALA4469D, ALA4487C, ALA4487D, ARG4448C, ARG4448D, ARG4449C, ARG4449D, ARG4452C, ARG4452D, ARG4455C, ARG4455D, ARG4462C, ARG4462D, ARG4537C, ARG4537D, ARG4551C, ARG4551D, ASN4443C, ASN4443D, ASN4457C, ASN4457D, ASN4463C, ASN4463D, ASN4468C, ASN4468D, ASN4470C, ASN4470D, ASN4549C, ASN4549D, ASP4464C, ASP4464D, ASP4497C, ASP4497D, ASP4499C, ASP4499D, ASP4540C, ASP4540D, ASP4550C, ASP4550D, CYS4477C, CYS4477D, GLN4453C, GLN4453D, GLN4546C, GLN4546D, GLU4446C, GLU4446D, GLU4471C, GLU4471D, HIS4466C, HIS4466D, ILE4486C, ILE4486D, ILE4547C, ILE4547D, LEU4451C, LEU4451D, LEU4465C, LEU4465D, LEU4479C, LEU4479D, LEU4483C, LEU4483D, LEU4534C, LEU4534D, LEU4541C, LEU4541D, LEU4542C, LEU4542D, LYS4467C, LYS4467D, LYS4476C, LYS4476D, LYS4482C, LYS4482D, LYS4498C, LYS4498D, LYS4535D, PHE4458C, PHE4458D, PHE4475C, PHE4475D, PHE4544C, PHE4544D, PHE4552C, PHE4552D, PRO4444C, PRO4502C, PRO4539C, PRO4539D, PRO4543C, PRO4543D, PRO4545C, PRO4545D, PRO4548C, PRO4548D, SER4459C, SER4459D, SER4480C, SER4480D, SER4496D, SER4533C, SER4533D, THR4536C, THR4536D, TRP4450C, TRP4450D, TRP4472C, TRP4472D, TYR4478C, TYR4478D, TYR4490C, TYR4490D, TYR4538C, TYR4538D, VAL4445C, VAL4445D, VAL4473C, VAL4473D, VAL4500D