3NZ2

crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor

• Total interactions analyzed: 66
• Total true interactions: 31
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 126
  • Norm. En. per Res.: -2.4378
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-6.1964	-6.0357	-282.269	-294.5011	128	6	6	11074	0	34	25
A-C	-17.3362	8.5576	-283.295	-292.0736	135	15	6	11372	0	31	28
A-D	-16.0491	106.4968	-71.1217	19.3259	34	7	1	2909	3	23	24
A-E	0.0	0.0	-0.6127	-0.6127	10	0	0	141	0	3	6
A-F	0.0	0.0	-0.9349	-0.9349	4	0	0	104	0	0	0
B-C	-18.1423	-6.2952	-259.638	-284.0755	131	16	6	10848	0	28	25
B-D	0.0	0.0	-0.0312	-0.0312	7	0	0	23	0	3	1
B-E	0.0	0.0	-1.4917	-1.4917	4	0	0	123	0	0	0
B-F	-2.7497	59.9672	-41.9534	15.2641	32	0	0	1689	6	22	20
C-D	0.0	0.0	-2.1372	-2.1372	4	0	0	96	0	0	0
C-E	-8.7742	73.1045	-71.4574	-7.1271	37	1	1	2708	3	25	22
C-F	0.0	0.0	-0.0019	-0.0019	4	0	0	2	0	2	1
D-E	-14.6102	2.1363	-233.426	-245.8999	127	15	6	10332	0	33	26
D-F	-14.8552	-9.2787	-282.631	-306.7649	135	7	6	11203	0	32	26
E-F	-8.5487	-3.6639	-273.969	-286.1816	135	11	6	11237	0	35	26
F-G	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	2	1
G-H	-15.9701	-15.7725	-275.423	-307.1655	126	13	4	11142	2	33	27
G-I	-18.876	2.8497	-275.764	-291.7903	131	11	6	11176	0	33	26
G-J	0.0	0.0	-1.0853	-1.0853	5	0	0	100	0	0	0
G-K	-19.8535	83.7362	-69.9193	-6.0366	36	2	1	2721	3	23	23
G-L	0.0	0.0	-0.3562	-0.3562	10	0	0	112	0	2	6
H-I	-14.6334	6.7804	-273.297	-281.15	133	13	6	11260	0	34	26
H-J	0.0	0.0	-0.067	-0.067	4	0	0	26	0	2	1
H-K	0.0	0.0	-2.0318	-2.0318	4	0	0	98	0	0	0
H-L	-12.9688	101.6894	-79.243	9.4776	35	1	1	2888	3	24	22
I-J	0.0	53.766	-34.5953	19.1707	30	0	0	1596	7	22	20
I-K	0.0	0.0	-0.0135	-0.0135	7	0	0	13	0	3	1
I-L	0.0	0.0	-1.0818	-1.0818	5	0	0	107	0	0	0
J-K	-15.6706	-3.5755	-271.885	-291.1311	128	11	6	11046	0	30	25
J-L	-7.7214	2.1038	-272.625	-278.2425	128	9	6	11038	0	33	27
K-L	-3.9535	0.772	-268.708	-271.8895	131	11	6	11102	0	32	26

Interface residues

• A-B: ALA111B, ALA122B, ALA152A, ALA157A, ALA158A, ALA158B, ALA18B, ALA29B, ARG118B, ARG119B, ARG120B, ARG153A, ARG181A, ARG26B, ARG31B, ARG45A, ASN141A, ASN141B, ASN145B, ASN159A, ASN159B, ASN163B, ASN37A, ASN37B, ASN83A, ASN85A, ASN85B, ASP116B, ASP134A, ASP135A, ASP169A, ASP41A, ASP78A, ASP98A, CYS61A, CYS68B, GLN107A, GLN107B, GLN121B, GLN146B, GLN28B, GLN38A, GLN38B, GLN63A, GLU124B, GLU23B, GLU35A, GLU35B, GLU42A, GLU69B, GLY103A, GLY139A, GLY140A, GLY140B, GLY173A, GLY174A, GLY174B, GLY30B, GLY77A, HIS113B, HIS58A, HIS67A, HIS67B, HIS79A, HIS99A, ILE102A, ILE138A, ILE36A, ILE82A, LEU101A, LEU115B, LEU171A, LEU180A, LEU183A, LEU32B, LEU34A, LEU34B, LEU40A, LEU89B, LYS184A, LYS33B, LYS59A, PHE108B, PHE66B, PHE81A, PRO104A, PRO176B, PRO64A, PRO65A, PRO65B, SER105A, SER105B, SER112B, SER114B, SER154A, SER160A, SER160B, SER182A, SER27B, SER39A, SER60A, THR106A, THR106B, THR125B, THR170A, THR175A, THR175B, THR80A, TRP123B, TRP137A, TYR109B, TYR117B, VAL100A, VAL136A, VAL142A, VAL142B, VAL143A, VAL143B, VAL155A, VAL156A, VAL161B, VAL162B, VAL172A, VAL62A, VAL86A, VAL86B, VAL87A, VAL87B
• A-C: ALA111A, ALA122A, ALA152C, ALA157C, ALA158A, ALA158C, ALA18A, ALA29A, ARG118A, ARG119A, ARG120A, ARG153C, ARG178C, ARG181C, ARG26A, ARG31A, ARG45C, ASN141A, ASN141C, ASN145A, ASN159A, ASN159C, ASN163A, ASN37A, ASN37C, ASN83C, ASN85A, ASN85C, ASP116A, ASP134C, ASP135C, ASP169C, ASP185C, ASP41C, ASP78C, ASP98C, CYS61C, CYS68A, GLN107A, GLN107C, GLN121A, GLN146A, GLN28A, GLN38A, GLN38C, GLN63C, GLU124A, GLU23A, GLU35A, GLU35C, GLU42C, GLU69A, GLY103C, GLY139C, GLY140A, GLY140C, GLY173C, GLY174A, GLY174C, GLY30A, GLY77C, HIS113A, HIS58C, HIS67A, HIS67C, HIS79C, HIS99C, ILE102C, ILE138C, ILE144A, ILE36C, ILE82C, LEU101C, LEU115A, LEU171C, LEU180C, LEU183C, LEU32A, LEU34A, LEU34C, LEU40C, LEU56C, LEU89A, LYS184C, LYS33A, LYS59C, PHE108A, PHE66A, PHE70A, PHE81C, PRO104A, PRO104C, PRO176A, PRO64C, PRO65A, PRO65C, SER105A, SER105C, SER112A, SER114A, SER154C, SER160A, SER160C, SER182C, SER27A, SER39C, SER60C, THR106A, THR106C, THR125A, THR170C, THR175A, THR175C, THR80C, TRP123A, TRP137C, TYR109A, TYR117A, VAL100C, VAL136C, VAL142A, VAL142C, VAL143A, VAL143C, VAL155C, VAL156C, VAL161A, VAL161C, VAL162A, VAL172C, VAL62C, VAL86A, VAL86C, VAL87A, VAL87C
• A-D: ALA43A, ALA43D, ALA47A, ALA47D, ARG31A, ARG31D, ARG45A, ARG45D, ASP41A, ASP41D, GLN28A, GLN38A, GLN38D, GLN49A, GLU35A, GLU35D, GLU42A, GLU42D, GLU44A, GLU44D, GLU51A, GLU51D, GLY30A, ILE36D, LEU32A, LEU32D, LEU34A, LEU34D, LEU40A, LEU40D, LEU48A, LEU48D, SER39A, SER39D
• A-E: ARG31A, ARG31E, GLN38A, GLN38E, GLU35A, GLU35E, LEU34A, LEU34E, SER27A, SER27E
• A-F: ASP41A, GLN38F, LEU40A, LEU40F
• B-C: ALA111C, ALA122C, ALA152B, ALA157B, ALA158B, ALA29C, ARG118C, ARG119C, ARG120C, ARG153B, ARG181B, ARG26C, ARG31C, ARG45B, ASN141B, ASN141C, ASN145C, ASN159B, ASN159C, ASN163C, ASN37B, ASN37C, ASN83B, ASN85B, ASN85C, ASP116C, ASP134B, ASP135B, ASP169B, ASP41B, ASP78B, ASP90C, ASP98B, CYS61B, CYS68C, GLN107B, GLN107C, GLN121C, GLN146C, GLN28C, GLN38B, GLN38C, GLN63B, GLU124C, GLU23C, GLU35B, GLU35C, GLU42B, GLU69C, GLY103B, GLY139B, GLY140B, GLY140C, GLY173B, GLY174B, GLY174C, GLY30C, GLY77B, HIS113C, HIS58B, HIS67B, HIS67C, HIS79B, HIS99B, ILE102B, ILE126C, ILE138B, ILE36B, ILE82B, LEU101B, LEU115C, LEU171B, LEU180B, LEU183B, LEU32C, LEU34B, LEU34C, LEU40B, LEU56B, LEU89C, LYS184B, LYS33C, LYS59B, PHE108C, PHE66C, PHE81B, PRO104B, PRO176C, PRO64B, PRO65B, PRO65C, SER105B, SER105C, SER112C, SER114C, SER154B, SER160B, SER160C, SER182B, SER27C, SER39B, SER60B, THR106B, THR106C, THR125C, THR170B, THR175B, THR175C, THR80B, TRP123C, TRP137B, TYR109C, TYR117C, TYR46B, VAL100B, VAL136B, VAL142B, VAL142C, VAL143B, VAL143C, VAL155B, VAL156B, VAL161B, VAL161C, VAL162C, VAL172B, VAL62B, VAL86B, VAL86C, VAL87B, VAL87C
• B-D: ARG31B, ARG31D, GLN38B, GLN38D, LEU34B, LEU34D, SER27B
• B-E: ASP41E, GLN38B, LEU40B, LEU40E
• B-F: ALA43B, ALA43F, ALA47B, ALA47F, ARG31B, ARG31F, ARG45B, ARG45F, ASP41B, ASP41F, GLN28B, GLN28F, GLN38B, GLN38F, GLU35B, GLU35F, GLU42B, GLU42F, GLU44B, GLU44F, GLU51B, GLU51F, LEU32B, LEU32F, LEU34B, LEU34F, LEU40B, LEU40F, LEU48B, LEU48F, SER39B, SER39F
• C-D: GLN38C, GLN38D, LEU40C, LEU40D
• C-E: ALA43C, ALA43E, ALA47C, ALA47E, ARG31C, ARG31E, ARG45C, ARG45E, ARG50E, ASP41C, ASP41E, GLN28E, GLN38C, GLN38E, GLN49E, GLU35C, GLU35E, GLU42C, GLU42E, GLU44C, GLU44E, GLU51C, GLU51E, GLY30E, ILE36C, ILE36E, LEU32C, LEU32E, LEU34C, LEU34E, LEU40C, LEU40E, LEU48C, LEU48E, SER39C, SER39E, TYR46E
• C-F: ARG31C, GLN38C, LEU34F, SER27F
• D-E: ALA111E, ALA122E, ALA152D, ALA157D, ALA158D, ALA158E, ALA29E, ARG118E, ARG119E, ARG120E, ARG153D, ARG181D, ARG26E, ARG31E, ARG45D, ASN141D, ASN141E, ASN145E, ASN159D, ASN159E, ASN163E, ASN37D, ASN37E, ASN83D, ASN85D, ASN85E, ASP116E, ASP134D, ASP135D, ASP169D, ASP185D, ASP41D, ASP78D, ASP98D, CYS61D, CYS68E, GLN107E, GLN121E, GLN28E, GLN38D, GLN38E, GLN63D, GLU124E, GLU23E, GLU35D, GLU35E, GLU42D, GLU69E, GLY103D, GLY139D, GLY140D, GLY140E, GLY173D, GLY174D, GLY174E, GLY30E, GLY77D, HIS113E, HIS58D, HIS67D, HIS67E, HIS79D, HIS99D, ILE102D, ILE138D, ILE36D, ILE82D, LEU101D, LEU115E, LEU171D, LEU180D, LEU183D, LEU32E, LEU34D, LEU34E, LEU40D, LEU89E, LYS184D, LYS33E, LYS59D, PHE108E, PHE66E, PHE81D, PRO104D, PRO176E, PRO64D, PRO65D, PRO65E, SER105D, SER105E, SER112E, SER114E, SER154D, SER160D, SER160E, SER182D, SER27E, SER39D, SER60D, THR106D, THR106E, THR125E, THR170D, THR175D, THR175E, THR80D, TRP123E, TRP137D, TYR109E, TYR117E, VAL100D, VAL136D, VAL142D, VAL142E, VAL143D, VAL143E, VAL155D, VAL156D, VAL161D, VAL161E, VAL162E, VAL172D, VAL62D, VAL86D, VAL86E, VAL87D, VAL87E
• D-F: ALA111D, ALA122D, ALA152F, ALA157F, ALA158D, ALA158F, ALA29D, ARG118D, ARG119D, ARG120D, ARG153F, ARG181F, ARG26D, ARG31D, ARG45F, ASN141D, ASN141F, ASN145D, ASN159D, ASN159F, ASN163D, ASN37D, ASN37F, ASN83F, ASN85D, ASN85F, ASP116D, ASP134F, ASP135F, ASP169F, ASP185F, ASP41F, ASP78F, ASP98F, CYS61F, CYS68D, GLN107D, GLN107F, GLN121D, GLN146D, GLN28D, GLN38D, GLN38F, GLN63F, GLU124D, GLU23D, GLU35D, GLU35F, GLU42F, GLU69D, GLY103F, GLY139F, GLY140D, GLY140F, GLY173F, GLY174D, GLY174F, GLY30D, GLY77F, HIS113D, HIS58F, HIS67D, HIS67F, HIS79F, HIS99F, ILE102F, ILE126D, ILE138F, ILE36F, ILE76F, ILE82F, LEU101F, LEU115D, LEU171F, LEU180F, LEU183F, LEU32D, LEU34D, LEU34F, LEU40F, LEU56F, LEU89D, LYS184F, LYS33D, LYS59F, PHE108D, PHE66D, PHE70D, PHE81F, PRO104F, PRO176D, PRO64F, PRO65D, PRO65F, SER105D, SER105F, SER112D, SER114D, SER154F, SER160D, SER160F, SER182F, SER27D, SER39F, SER60F, THR106D, THR106F, THR110D, THR125D, THR170F, THR175D, THR175F, THR80F, TRP123D, TRP137F, TYR109D, TYR117D, TYR46F, VAL100F, VAL136F, VAL142D, VAL142F, VAL143D, VAL143F, VAL155F, VAL156F, VAL161D, VAL161F, VAL162D, VAL172F, VAL62F, VAL86D, VAL86F, VAL87D, VAL87F
• E-F: ALA111F, ALA122F, ALA152E, ALA157E, ALA158E, ALA158F, ALA29F, ARG118F, ARG119F, ARG120F, ARG153E, ARG178E, ARG178F, ARG181E, ARG26F, ARG31F, ARG45E, ASN141E, ASN141F, ASN145F, ASN159E, ASN159F, ASN163F, ASN37E, ASN37F, ASN83E, ASN85E, ASN85F, ASP116F, ASP134E, ASP135E, ASP169E, ASP185E, ASP41E, ASP78E, ASP98E, CYS61E, CYS68F, GLN107F, GLN121F, GLN146F, GLN28F, GLN38E, GLN38F, GLN63E, GLU124F, GLU23F, GLU35E, GLU35F, GLU42E, GLU69F, GLY103E, GLY139E, GLY140E, GLY140F, GLY151E, GLY173E, GLY174E, GLY174F, GLY30F, GLY77E, HIS113F, HIS58E, HIS67E, HIS67F, HIS79E, HIS99E, ILE102E, ILE138E, ILE144F, ILE36E, ILE76E, ILE82E, LEU101E, LEU115F, LEU171E, LEU180E, LEU183E, LEU32F, LEU34E, LEU34F, LEU40E, LEU56E, LEU89F, LYS184E, LYS33F, LYS59E, PHE108F, PHE66F, PHE81E, PRO104E, PRO176F, PRO64E, PRO65E, PRO65F, SER105E, SER105F, SER112F, SER114F, SER154E, SER160E, SER160F, SER182E, SER27F, SER39E, SER60E, THR106E, THR106F, THR125F, THR170E, THR175E, THR175F, THR80E, TRP123F, TRP137E, TYR109F, TYR117F, TYR46E, VAL100E, VAL136E, VAL142E, VAL142F, VAL143E, VAL143F, VAL155E, VAL156E, VAL161E, VAL161F, VAL162F, VAL172E, VAL62E, VAL86E, VAL86F, VAL87E, VAL87F
• F-G: LYS11F, PRO168G
• G-H: ALA111G, ALA122G, ALA152H, ALA157H, ALA158G, ALA158H, ALA18G, ALA29G, ARG118G, ARG119G, ARG120G, ARG153H, ARG181H, ARG26G, ARG31G, ARG45H, ASN141G, ASN141H, ASN145G, ASN159G, ASN159H, ASN163G, ASN37G, ASN37H, ASN83H, ASN85G, ASN85H, ASP116G, ASP134H, ASP135H, ASP169H, ASP185H, ASP78H, ASP98H, CYS61H, CYS68G, GLN107G, GLN121G, GLN146G, GLN28G, GLN38G, GLN38H, GLN63H, GLU124G, GLU23G, GLU35G, GLU42H, GLU69G, GLY103H, GLY139H, GLY140G, GLY140H, GLY173H, GLY174G, GLY174H, GLY30G, HIS113G, HIS58H, HIS67G, HIS67H, HIS79H, HIS99H, ILE102H, ILE138H, ILE144G, ILE36H, ILE82H, LEU101H, LEU115G, LEU171H, LEU180H, LEU183H, LEU32G, LEU34G, LEU34H, LEU40H, LEU89G, LYS184H, LYS33G, LYS59H, PHE108G, PHE66G, PHE81H, PRO104H, PRO176G, PRO64H, PRO65G, PRO65H, SER105G, SER105H, SER112G, SER114G, SER154H, SER160G, SER160H, SER182H, SER27G, SER39H, SER60H, THR106G, THR106H, THR125G, THR170H, THR175G, THR175H, THR80H, TRP123G, TRP137H, TYR109G, TYR117G, VAL100H, VAL136H, VAL142G, VAL142H, VAL143G, VAL143H, VAL155H, VAL156H, VAL161G, VAL161H, VAL162G, VAL62H, VAL86G, VAL86H, VAL87G, VAL87H
• G-I: ALA111I, ALA122I, ALA152G, ALA157G, ALA158G, ALA158I, ALA18I, ALA29I, ARG118I, ARG119I, ARG120I, ARG153G, ARG178G, ARG181G, ARG26I, ARG31I, ARG45G, ASN141G, ASN141I, ASN145I, ASN159G, ASN159I, ASN163I, ASN37G, ASN37I, ASN83G, ASN85G, ASN85I, ASP116I, ASP134G, ASP135G, ASP169G, ASP41G, ASP78G, ASP98G, CYS61G, CYS68I, GLN107I, GLN121I, GLN146I, GLN28I, GLN38G, GLN38I, GLN63G, GLU124I, GLU23I, GLU35I, GLU42G, GLU69I, GLY103G, GLY139G, GLY140G, GLY140I, GLY173G, GLY174G, GLY174I, GLY30I, GLY77G, HIS113I, HIS58G, HIS67G, HIS67I, HIS79G, HIS99G, ILE102G, ILE126I, ILE138G, ILE144I, ILE36G, ILE82G, LEU101G, LEU115I, LEU171G, LEU180G, LEU183G, LEU32I, LEU34G, LEU34I, LEU40G, LEU56G, LEU89I, LYS184G, LYS33I, LYS59G, PHE108I, PHE66I, PHE81G, PRO104G, PRO176I, PRO64G, PRO65G, PRO65I, SER105G, SER105I, SER112I, SER114I, SER154G, SER160G, SER160I, SER182G, SER27I, SER39G, SER60G, THR106G, THR106I, THR125I, THR170G, THR175G, THR175I, THR80G, TRP123I, TRP137G, TYR109I, TYR117I, TYR46G, VAL100G, VAL136G, VAL142G, VAL142I, VAL143G, VAL143I, VAL155G, VAL156G, VAL161G, VAL161I, VAL162I, VAL172G, VAL62G, VAL86G, VAL86I, VAL87I
• G-J: ASP41G, GLN38G, GLN38J, LEU40G, LEU40J
• G-K: ALA43G, ALA43K, ALA47G, ALA47K, ARG31G, ARG31K, ARG45G, ARG45K, ARG50G, ASP41G, ASP41K, GLN28G, GLN38G, GLN38K, GLN49G, GLU35G, GLU35K, GLU42G, GLU42K, GLU44G, GLU44K, GLU51G, GLU51K, ILE36G, ILE36K, LEU32G, LEU32K, LEU34G, LEU34K, LEU40G, LEU40K, LEU48G, LEU48K, SER39G, SER39K, TYR46G
• G-L: ARG31G, ARG31L, GLN38G, GLN38L, GLU35G, GLU35L, LEU34G, LEU34L, SER27G, SER27L
• H-I: ALA111H, ALA122H, ALA152I, ALA157I, ALA158H, ALA158I, ALA29H, ARG118H, ARG119H, ARG120H, ARG153I, ARG178I, ARG181I, ARG26H, ARG31H, ARG45I, ASN141H, ASN141I, ASN145H, ASN159H, ASN159I, ASN163H, ASN37H, ASN37I, ASN83I, ASN85H, ASN85I, ASP116H, ASP134I, ASP135I, ASP169I, ASP185I, ASP41I, ASP78I, ASP90H, ASP98I, CYS61I, CYS68H, GLN107H, GLN107I, GLN121H, GLN146H, GLN28H, GLN38H, GLN38I, GLN63I, GLU124H, GLU23H, GLU35H, GLU35I, GLU42I, GLU69H, GLY103I, GLY139I, GLY140H, GLY140I, GLY173I, GLY174H, GLY174I, GLY30H, GLY77I, HIS113H, HIS58I, HIS67H, HIS67I, HIS79I, HIS99I, ILE102I, ILE138I, ILE144H, ILE36I, ILE82I, LEU101I, LEU115H, LEU171I, LEU180I, LEU183I, LEU32H, LEU34H, LEU34I, LEU40I, LEU56I, LEU89H, LYS184I, LYS33H, LYS59I, PHE108H, PHE66H, PHE81I, PRO104I, PRO176H, PRO64I, PRO65H, PRO65I, SER105H, SER105I, SER112H, SER114H, SER154I, SER160H, SER160I, SER182I, SER27H, SER39I, SER60I, THR106H, THR106I, THR125H, THR170I, THR175H, THR175I, THR80I, TRP123H, TRP137I, TYR109H, TYR117H, VAL100I, VAL136I, VAL142H, VAL142I, VAL143H, VAL143I, VAL155I, VAL156I, VAL161H, VAL161I, VAL162H, VAL172I, VAL62I, VAL86H, VAL86I, VAL87H, VAL87I
• H-J: GLN38H, GLN38J, LEU34H, LEU34J
• H-K: GLN38H, GLN38K, LEU40H, LEU40K
• H-L: ALA43H, ALA43L, ALA47H, ALA47L, ARG31H, ARG31L, ARG45H, ARG45L, ASP41H, ASP41L, GLN28L, GLN38H, GLN38L, GLN49L, GLU35H, GLU35L, GLU42H, GLU42L, GLU44H, GLU44L, GLU51H, GLU51L, GLY30L, ILE36H, ILE36L, LEU32H, LEU32L, LEU34H, LEU34L, LEU40H, LEU40L, LEU48H, LEU48L, SER39H, SER39L
• I-J: ALA43I, ALA43J, ALA47I, ARG31I, ARG31J, ARG45I, ARG45J, ASP41I, ASP41J, GLN28J, GLN38I, GLN38J, GLU35I, GLU35J, GLU42I, GLU42J, GLU44I, GLU44J, GLU51I, GLU51J, LEU32I, LEU32J, LEU34I, LEU34J, LEU40I, LEU40J, LEU48I, LEU48J, SER39I, SER39J
• I-K: ARG31I, ARG31K, GLN38I, GLN38K, LEU34I, LEU34K, SER27I
• I-L: ASP41L, GLN38I, LEU40I, LEU40L, SER39I
• J-K: ALA111K, ALA122K, ALA152J, ALA157J, ALA158J, ALA158K, ALA29K, ARG118K, ARG119K, ARG120K, ARG153J, ARG178J, ARG181J, ARG26K, ARG31K, ARG45J, ASN141J, ASN141K, ASN145K, ASN159J, ASN159K, ASN163K, ASN37J, ASN37K, ASN83J, ASN85J, ASN85K, ASP116K, ASP134J, ASP135J, ASP169J, ASP41J, ASP78J, ASP98J, CYS61J, CYS68K, GLN107K, GLN121K, GLN146K, GLN28K, GLN38J, GLN38K, GLN63J, GLU124K, GLU23K, GLU35J, GLU35K, GLU42J, GLU69K, GLY103J, GLY139J, GLY140J, GLY140K, GLY173J, GLY174J, GLY174K, GLY30K, GLY77J, HIS113K, HIS58J, HIS67J, HIS67K, HIS79J, HIS99J, ILE102J, ILE138J, ILE36J, ILE82J, LEU101J, LEU115K, LEU171J, LEU180J, LEU183J, LEU32K, LEU34J, LEU34K, LEU40J, LEU56J, LEU89K, LYS184J, LYS33K, LYS59J, PHE108K, PHE66K, PHE81J, PRO104J, PRO176K, PRO64J, PRO65J, PRO65K, SER105J, SER105K, SER112K, SER114K, SER154J, SER160J, SER160K, SER182J, SER27K, SER39J, SER60J, THR106J, THR106K, THR125K, THR170J, THR175J, THR175K, THR80J, TRP123K, TRP137J, TYR109K, TYR117K, VAL100J, VAL136J, VAL142J, VAL142K, VAL143J, VAL143K, VAL155J, VAL156J, VAL161J, VAL161K, VAL162K, VAL172J, VAL62J, VAL86J, VAL86K, VAL87K
• J-L: ALA111J, ALA122J, ALA152L, ALA157L, ALA158J, ALA158L, ALA29J, ARG118J, ARG119J, ARG120J, ARG153L, ARG178L, ARG181L, ARG26J, ARG31J, ARG45L, ASN141J, ASN141L, ASN145J, ASN159J, ASN159L, ASN163J, ASN37J, ASN37L, ASN83L, ASN85J, ASN85L, ASP116J, ASP134L, ASP135L, ASP169L, ASP185L, ASP41L, ASP78L, ASP98L, CYS61L, CYS68J, GLN107J, GLN121J, GLN146J, GLN28J, GLN38J, GLN38L, GLN63L, GLU124J, GLU23J, GLU35J, GLU42L, GLU69J, GLY103L, GLY139L, GLY140J, GLY140L, GLY173L, GLY174J, GLY174L, GLY30J, GLY77L, HIS113J, HIS58L, HIS67J, HIS67L, HIS79L, HIS99L, ILE102L, ILE138L, ILE144J, ILE82L, LEU101L, LEU115J, LEU171L, LEU180L, LEU183L, LEU32J, LEU34J, LEU34L, LEU40L, LEU56L, LEU89J, LYS184L, LYS33J, LYS59L, PHE108J, PHE66J, PHE81L, PRO104L, PRO176J, PRO64L, PRO65J, PRO65L, SER105J, SER105L, SER112J, SER114J, SER154L, SER160J, SER160L, SER182L, SER27J, SER39L, SER60L, THR106J, THR106L, THR125J, THR170L, THR175J, THR175L, THR80L, TRP123J, TRP137L, TYR109J, TYR117J, VAL100L, VAL136L, VAL142J, VAL142L, VAL143J, VAL143L, VAL155L, VAL156L, VAL161J, VAL161L, VAL162J, VAL172L, VAL62L, VAL86J, VAL86L, VAL87J
• K-L: ALA111L, ALA122L, ALA152K, ALA157K, ALA158K, ALA158L, ALA24L, ALA29L, ARG118L, ARG119L, ARG120L, ARG153K, ARG178K, ARG181K, ARG26L, ARG31L, ARG45K, ASN141K, ASN141L, ASN145L, ASN159K, ASN159L, ASN163L, ASN37K, ASN37L, ASN83K, ASN85K, ASN85L, ASP116L, ASP134K, ASP135K, ASP169K, ASP41K, ASP78K, ASP98K, CYS61K, CYS68L, GLN107K, GLN107L, GLN121L, GLN146L, GLN28L, GLN38K, GLN38L, GLN63K, GLU124L, GLU23L, GLU35K, GLU35L, GLU42K, GLU69L, GLY103K, GLY139K, GLY140K, GLY140L, GLY173K, GLY174K, GLY174L, GLY30L, GLY77K, HIS113L, HIS58K, HIS67K, HIS67L, HIS79K, HIS99K, ILE102K, ILE126L, ILE138K, ILE36K, ILE82K, LEU101K, LEU115L, LEU171K, LEU180K, LEU183K, LEU32L, LEU34K, LEU34L, LEU40K, LEU89L, LYS184K, LYS33L, LYS59K, PHE108L, PHE66L, PHE81K, PRO104K, PRO176L, PRO64K, PRO65K, PRO65L, SER105K, SER105L, SER112L, SER114L, SER154K, SER160K, SER160L, SER182K, SER27L, SER39K, SER60K, THR106K, THR106L, THR125L, THR170K, THR175K, THR175L, THR80K, TRP123L, TRP137K, TYR109L, TYR117L, VAL100K, VAL136K, VAL142K, VAL142L, VAL143K, VAL143L, VAL155K, VAL156K, VAL161K, VAL161L, VAL162L, VAL172K, VAL62K, VAL86K, VAL86L, VAL87K, VAL87L