3NPZ

prolactin receptor (prlr) complexed with the natural hormone (prl)

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 113
  • Norm. En. per Res.: -3.8139
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-42.3385	-50.9817	-337.654	-430.9742	113	19	2	12696	8	50	52
A-C	-20.9071	-3.776	-190.886	-215.569	81	10	1	8530	6	32	30
B-C	-15.1911	-21.4937	-164.026	-200.7108	76	7	2	6329	2	32	26

Interface residues

• A-B: ALA54A, ALA72A, ARG176A, ARG177A, ARG192A, ASN184A, ASN196A, ASN197A, ASN198A, ASN31A, ASN56A, ASP134B, ASP16B, ASP178A, ASP183A, ASP187B, ASP68A, ASP96B, CYS174A, CYS191A, CYS199A, CYS58A, GLN67B, GLN71A, GLN73A, GLU143B, GLU18B, GLU43B, GLU45B, GLU67A, GLU70A, GLY138B, GLY189B, GLY44B, GLY49A, HIS163B, HIS173A, HIS180A, HIS188B, HIS195A, HIS27A, HIS30A, ILE100B, ILE132B, ILE182A, ILE29A, ILE51A, ILE55A, ILE71B, ILE74B, ILE76B, LEU172A, LEU175A, LEU186A, LEU188A, LEU189A, LEU32A, LEU93B, LYS136B, LYS17B, LYS181A, LYS185B, LYS187A, LYS190A, LYS42B, LYS46B, LYS53A, LYS66B, LYS69A, LYS73B, MET142B, PHE140B, PHE160B, PHE37A, PHE50A, PHE80A, PRO129B, PRO186B, PRO66A, PRO92B, SER179A, SER26A, SER34A, SER41B, SER57A, SER61A, SER65B, SER70B, THR133B, THR137B, THR141B, THR165B, THR19B, THR52A, THR65A, THR69B, THR98B, TRP139B, TRP72B, TYR169A, TYR185A, TYR190B, TYR28A, TYR68B, TYR75B, TYR94B, TYR99B, VAL101B, VAL135B, VAL23A, VAL24A, VAL95B, VAL97B
• A-C: ALA22A, ARG125A, ARG13C, ARG16A, ARG21A, ASN31A, ASP134C, ASP16C, ASP17A, ASP183A, ASP187C, ASP20A, ASP96C, CYS11A, CYS12C, CYS4A, GLN122A, GLN12A, GLN67C, GLU118A, GLU121A, GLU128A, GLU131A, GLU18C, GLU35A, GLU43C, GLY129A, GLY138C, GLY44C, HIS188C, HIS27A, ILE100C, ILE132C, ILE133A, ILE3A, ILE71C, ILE74C, ILE76C, LEU126A, LEU127A, LEU132A, LEU186A, LEU18A, LEU25A, LEU32A, LEU93C, LYS124A, LYS136C, LYS17C, LYS187A, LYS190A, LYS42C, LYS66C, LYS73C, MET130A, PHE140C, PHE19A, PRO2A, SER26A, SER70C, THR123A, THR131C, THR133C, THR137C, THR14A, THR19C, THR69C, THR98C, TRP139C, TRP72C, TYR190C, TYR28A, TYR75C, TYR94C, TYR99C, VAL135C, VAL13A, VAL23A, VAL24A, VAL95C, VAL97C
• B-C: ALA153B, ARG147B, ASP134C, ASP171B, ASP171C, ASP187B, GLN115C, GLN164B, GLN164C, GLN166B, GLN166C, GLN176B, GLU112C, GLU143B, GLU143C, GLU152B, GLU154B, GLU155B, GLU157B, GLU157C, GLY138C, GLY162B, GLY162C, HIS159B, HIS159C, HIS163B, HIS163C, HIS188B, ILE146B, ILE146C, ILE158B, ILE158C, LEU116B, LEU123B, LEU123C, LEU148B, LEU172B, LYS114C, LYS119C, LYS120B, LYS120C, LYS126C, LYS149B, LYS168B, LYS168C, LYS185B, MET142B, MET142C, PHE140C, PHE160B, PHE160C, PHE167B, PHE167C, PHE170B, PHE170C, PRO150B, PRO174B, THR137C, THR141B, THR141C, THR161B, THR161C, THR165C, TRP124C, TRP127C, TRP139C, TRP156B, TYR122B, TYR122C, TYR144C, TYR173B, TYR178B, VAL125C, VAL135C, VAL169B, VAL169C