3NHQ

the dark pfr structure of the photosensory core module of p. aeruginosa bacteriophytochrome

• Total interactions analyzed: 28
• Total true interactions: 20
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 9
  • Norm. En. per Res.: -3.4594
• Hub Node: C(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-28.8494	-137.2496	-404.218	-570.317	193	16	18	19867	9	51	65
A-C	-6.6427	-16.2689	-8.2227	-31.1344	9	0	0	240	2	7	8
A-G	-117.33	1.2321	-330.984	-447.0819	147	35	6	13635	3	112	85
A-H	-16.0421	-24.5271	-42.8703	-83.4395	29	5	1	2092	2	4	7
B-D	-3.4711	0.0	-3.9344	-7.4055	9	0	0	185	0	7	9
B-G	0.0	0.0	-4.6482	-4.6482	19	0	1	406	0	3	4
B-H	-13.5006	-5.8892	-151.484	-170.8738	114	5	0	6799	3	57	59
C-D	-62.7077	-143.6131	-409.685	-616.0058	196	41	19	20695	10	54	69
C-E	-112.8749	-26.5892	-306.685	-446.149	142	25	7	12613	3	104	81
C-F	0.0	0.0	-20.7718	-20.7718	18	1	1	1081	0	4	4
C-G	-42.1123	-83.6401	-215.973	-341.7253	128	11	0	8857	7	55	56
C-H	-2.7992	-15.0613	-39.1608	-57.0213	27	0	2	1935	1	6	8
D-E	-15.2779	-15.3678	-41.7564	-72.402	27	3	1	1887	2	5	4
D-F	-20.2749	-27.4776	-145.914	-193.6665	113	2	0	6570	7	55	57
D-G	0.0	-15.4671	-24.4698	-39.9369	28	2	1	1570	2	4	6
D-H	-106.2529	-80.6006	-338.51	-525.3635	165	31	6	14394	5	107	87
E-F	-53.9769	-140.9275	-441.955	-636.8594	199	25	19	20955	7	55	66
E-G	0.0	-10.2211	-4.5054	-14.7266	9	0	0	190	1	7	9
F-H	0.0	0.0	-0.9817	-0.9817	13	0	0	110	0	8	8
G-H	-30.7892	-122.6598	-395.991	-549.44	201	38	19	20735	11	53	65

Interface residues

• A-B: ALA127A, ALA127B, ALA132A, ALA132B, ALA301A, ALA301B, ALA312A, ALA312B, ALA324A, ALA324B, ALA326A, ALA326B, ALA329A, ALA329B, ALA332A, ALA332B, ARG113B, ARG129A, ARG129B, ARG153B, ARG289A, ARG289B, ARG305A, ARG305B, ARG316A, ARG316B, ARG321A, ARG321B, ARG322A, ARG322B, ARG327A, ARG327B, ARG328A, ARG328B, ARG330A, ARG330B, ARG70B, ASN126A, ASN126B, ASN138A, ASN138B, ASN495B, ASN84A, ASN84B, ASP116A, ASP139A, ASP139B, ASP331A, ASP331B, ASP488A, ASP488B, ASP96B, CYS299A, CYS299B, GLN128A, GLN128B, GLN133A, GLN133B, GLN135A, GLN135B, GLN205B, GLN293A, GLN293B, GLN297A, GLN297B, GLN308A, GLN308B, GLU150B, GLU304A, GLU304B, GLU307A, GLU307B, GLU313A, GLU313B, GLU320A, GLU320B, GLU491A, GLU491B, GLU74A, GLU74B, GLY267A, GLY267B, GLY309A, GLY309B, GLY80A, GLY99B, HIS100B, HIS137A, HIS137B, ILE120A, ILE120B, ILE130A, ILE130B, ILE131A, ILE131B, ILE208A, ILE208B, ILE264A, ILE294A, ILE294B, ILE302A, ILE302B, ILE311A, ILE311B, ILE98B, LEU118A, LEU125A, LEU125B, LEU136A, LEU136B, LEU143A, LEU143B, LEU306A, LEU306B, LEU314A, LEU314B, LEU315A, LEU315B, LEU323A, LEU323B, LEU325A, LEU325B, LEU485A, LEU485B, LEU487A, LEU489A, LEU492A, LEU492B, LEU494A, LYS484A, LYS484B, MET154B, MET290A, MET290B, MET71B, PHE123A, PHE123B, PHE292A, PHE292B, PHE295A, PHE295B, PRO207A, PRO207B, PRO287A, PRO287B, PRO81A, PRO81B, SER119A, SER119B, SER122A, SER122B, SER142A, SER291A, SER291B, SER296A, SER296B, SER300A, SER300B, SER318A, SER318B, SER83A, SER83B, SER85A, SER85B, THR117A, THR121A, THR121B, THR124A, THR124B, THR140A, THR140B, THR319A, THR319B, TRP82A, TRP82B, TYR286A, TYR286B, VAL134A, VAL134B, VAL265A, VAL265B, VAL266A, VAL266B, VAL288A, VAL288B, VAL298A, VAL298B, VAL303A, VAL303B, VAL317A, VAL317B, VAL86B, VAL97B
• A-C: ASN79C, ASP181A, GLU104C, GLU180A, GLY78C, LYS103C, LYS440A, LYS443A, THR77C
• A-G: ALA141A, ALA141G, ALA175A, ALA175G, ALA324G, ALA332A, ALA332G, ALA338A, ALA338G, ALA340A, ALA340G, ALA347A, ALA347G, ALA348A, ALA355A, ALA355G, ARG129A, ARG152G, ARG153A, ARG153G, ARG159G, ARG178A, ARG178G, ARG327A, ARG327G, ARG328A, ARG328G, ARG362A, ARG362G, ARG367A, ARG367G, ARG434A, ARG434G, ARG436A, ARG436G, ASN138G, ASN146A, ASN146G, ASP139A, ASP139G, ASP149A, ASP149G, ASP181G, ASP331A, ASP331G, ASP333A, ASP333G, ASP334A, ASP334G, ASP343A, ASP343G, ASP344A, ASP344G, ASP353A, ASP353G, ASP369A, ASP369G, GLN133A, GLU172A, GLU172G, GLU176A, GLU176G, GLU180A, GLU180G, GLU183A, GLU183G, GLU371A, GLU371G, GLU442G, GLY187A, GLY187G, GLY337A, GLY337G, GLY345A, GLY345G, GLY354G, GLY360A, GLY360G, GLY361A, GLY361G, GLY368A, GLY368G, GLY438A, GLY438G, GLY439A, GLY439G, HIS137A, HIS137G, HIS341A, HIS341G, HIS433A, HIS433G, ILE346A, ILE366A, ILE366G, ILE435A, ILE435G, LEU136A, LEU182A, LEU182G, LEU186A, LEU186G, LEU335A, LEU335G, LEU339A, LEU339G, LEU356A, LEU356G, LEU359A, LEU359G, LEU364A, LEU364G, LYS440A, LYS440G, LYS443G, MET358A, MET358G, PHE336A, PHE336G, PHE370A, PHE370G, PRO342A, PRO342G, PRO441A, PRO441G, SER142A, SER142G, SER145A, SER145G, SER177A, SER177G, SER184A, SER184G, SER365A, SER365G, THR363A, THR363G, TRP437A, TRP437G, TYR185A, TYR185G, VAL174A, VAL174G, VAL357A, VAL357G, VAL432A, VAL432G
• A-H: ALA132A, ARG129A, ARG153A, ARG330H, ARG418H, ARG486H, ASN146A, ASN495H, ASP488H, CYS493H, GLN128A, GLN133A, GLN135A, GLN419H, GLU491H, HIS137A, HIS496H, ILE130A, ILE131A, LEU125A, LEU136A, LEU487H, LEU489H, LEU492H, LEU494H, MET490H, PHE416H, SER142A, VAL134A
• B-D: ALA34B, ARG33B, ASN79B, ASP181D, GLU104B, GLU180D, GLU228B, LEU444D, LYS443D
• B-G: ALA132G, ALA497B, ARG129G, ARG153G, ARG418B, ASN138G, ASN146G, ASN495B, ASP149G, GLN133G, GLU150G, GLU491B, HIS137G, HIS496B, LEU136G, LEU487B, LEU494B, MET490B, SER142G
• B-H: ALA192H, ALA197B, ALA197H, ALA199B, ALA199H, ALA497B, ARG166B, ARG166H, ARG200B, ARG200H, ARG201B, ARG201H, ARG362B, ARG362H, ARG383B, ARG383H, ARG387B, ARG387H, ARG415B, ARG415H, ARG418B, ARG418H, ARG486B, ARG486H, ASN11B, ASN206B, ASN79B, ASP14B, ASP14H, ASP168B, ASP168H, ASP169B, ASP169H, ASP384B, ASP384H, ASP388B, ASP388H, CYS12B, GLN198B, GLN198H, GLN205B, GLN205H, GLN297B, GLN379B, GLN382B, GLN382H, GLN419B, GLN419H, GLU104B, GLU104H, GLU13B, GLU13H, GLU15B, GLU386B, GLU386H, GLU420B, GLU420H, GLY267B, GLY267H, GLY268B, GLY268H, GLY360B, GLY360H, GLY361B, GLY361H, GLY80B, GLY80H, HIS167B, HIS167H, HIS18B, HIS18H, HIS417B, HIS417H, ILE17B, ILE195B, ILE195H, ILE204B, ILE204H, LEU202B, LEU202H, LEU270B, LEU270H, LEU381B, LEU381H, LYS103B, LYS103H, LYS269B, LYS269H, MET490B, MET490H, PHE165B, PHE165H, PRO16B, PRO16H, PRO196B, PRO196H, PRO207B, PRO385B, PRO385H, PRO81B, PRO81H, SER421B, SER421H, TRP271B, TRP271H, TRP82H, TYR102B, TYR102H, TYR237B, TYR237H, VAL265B, VAL265H, VAL266B, VAL266H
• C-D: ALA127C, ALA127D, ALA132C, ALA132D, ALA301C, ALA301D, ALA312C, ALA312D, ALA324C, ALA324D, ALA326C, ALA326D, ALA332D, ARG113C, ARG113D, ARG129C, ARG129D, ARG289C, ARG289D, ARG305C, ARG305D, ARG316C, ARG316D, ARG321C, ARG321D, ARG322C, ARG322D, ARG327C, ARG327D, ARG328C, ARG328D, ARG330C, ARG330D, ARG70D, ASN126C, ASN126D, ASN138C, ASN138D, ASN495C, ASN495D, ASN84C, ASN84D, ASP116C, ASP139C, ASP139D, ASP331C, ASP331D, ASP333D, ASP488C, ASP488D, ASP96C, ASP96D, CYS299C, CYS299D, GLN128C, GLN128D, GLN133C, GLN133D, GLN135C, GLN135D, GLN205C, GLN293C, GLN293D, GLN297C, GLN297D, GLN308C, GLN308D, GLU304C, GLU304D, GLU307C, GLU307D, GLU313C, GLU313D, GLU320C, GLU320D, GLU491C, GLU491D, GLU87C, GLU87D, GLY267C, GLY267D, GLY309C, GLY309D, GLY99C, HIS100C, HIS137C, HIS137D, HIS496C, HIS496D, ILE120C, ILE120D, ILE130C, ILE130D, ILE131C, ILE131D, ILE208D, ILE264D, ILE294C, ILE294D, ILE302C, ILE302D, ILE311C, ILE311D, ILE98C, ILE98D, LEU118C, LEU118D, LEU125C, LEU125D, LEU136C, LEU136D, LEU143C, LEU143D, LEU306C, LEU306D, LEU314C, LEU314D, LEU315C, LEU315D, LEU323C, LEU323D, LEU325C, LEU325D, LEU485C, LEU485D, LEU487C, LEU487D, LEU489D, LEU492C, LEU492D, LEU94D, LYS484C, LYS484D, MET154D, MET290C, MET290D, MET71C, PHE123C, PHE123D, PHE292C, PHE292D, PHE295C, PHE295D, PHE95D, PRO207C, PRO207D, PRO285D, PRO287C, PRO287D, PRO81C, SER119C, SER119D, SER122C, SER122D, SER291C, SER291D, SER296C, SER296D, SER300C, SER300D, SER318C, SER318D, SER83C, SER83D, SER85C, SER85D, THR117C, THR117D, THR121C, THR121D, THR124C, THR124D, THR140C, THR140D, THR319C, THR319D, THR88D, TRP82C, TYR286C, TYR286D, VAL134C, VAL134D, VAL265C, VAL265D, VAL266C, VAL266D, VAL288C, VAL288D, VAL298C, VAL298D, VAL303C, VAL303D, VAL317C, VAL317D, VAL86C, VAL86D
• C-E: ALA141C, ALA141E, ALA175C, ALA332C, ALA332E, ALA338C, ALA338E, ALA340C, ALA340E, ALA347C, ALA347E, ALA355C, ALA355E, ARG152C, ARG153C, ARG153E, ARG159C, ARG159E, ARG164C, ARG178C, ARG178E, ARG179C, ARG327C, ARG328C, ARG328E, ARG362C, ARG362E, ARG367C, ARG367E, ARG434C, ARG434E, ARG436C, ARG436E, ASN146C, ASN146E, ASP139C, ASP139E, ASP149C, ASP149E, ASP181C, ASP331C, ASP331E, ASP333C, ASP333E, ASP334C, ASP334E, ASP343C, ASP343E, ASP344C, ASP344E, ASP353C, ASP353E, ASP369C, ASP369E, GLN133E, GLU172C, GLU176C, GLU176E, GLU180C, GLU180E, GLU183C, GLU183E, GLU371C, GLU371E, GLU442C, GLU442E, GLY187C, GLY187E, GLY337C, GLY337E, GLY345C, GLY345E, GLY360C, GLY360E, GLY361C, GLY361E, GLY368C, GLY368E, GLY438C, GLY438E, GLY439C, GLY439E, HIS137E, HIS341C, HIS341E, HIS429C, HIS433C, HIS433E, ILE346E, ILE366C, ILE366E, ILE435C, ILE435E, LEU136E, LEU182C, LEU182E, LEU186C, LEU186E, LEU335C, LEU335E, LEU339C, LEU339E, LEU356C, LEU356E, LEU359C, LEU359E, LEU364C, LEU364E, LYS440C, LYS440E, MET358C, MET358E, PHE336C, PHE336E, PHE370C, PHE370E, PRO342C, PRO342E, PRO441C, PRO441E, SER142C, SER142E, SER145C, SER145E, SER177C, SER177E, SER184C, SER184E, SER365C, SER365E, THR363C, THR363E, TRP437C, TRP437E, TYR185C, TYR185E, VAL174C, VAL174E, VAL357C, VAL357E, VAL432C, VAL432E
• C-F: ALA132C, ALA497F, ARG129C, ARG153C, ARG418F, ASN146C, ASN495F, ASP149C, GLN133C, GLU150C, GLU491F, HIS137C, ILE130C, LEU136C, LEU494F, LEU498F, MET154C, MET490F
• C-G: ALA10C, ALA10G, ALA192C, ALA197C, ALA197G, ALA199C, ALA199G, ALA497G, ARG166C, ARG166G, ARG200C, ARG200G, ARG201C, ARG201G, ARG362C, ARG383C, ARG383G, ARG387C, ARG387G, ARG415C, ARG415G, ARG418C, ARG418G, ARG486C, ARG486G, ASN11C, ASN11G, ASN206C, ASN79C, ASN79G, ASP14C, ASP14G, ASP168C, ASP168G, ASP169C, ASP169G, ASP333G, ASP384C, ASP384G, ASP388C, ASP388G, CYS12C, CYS493C, GLN198C, GLN198G, GLN205C, GLN205G, GLN382C, GLN382G, GLN419C, GLN419G, GLU104C, GLU104G, GLU13C, GLU13G, GLU15C, GLU15G, GLU386C, GLU386G, GLU420C, GLU420G, GLY267C, GLY267G, GLY268C, GLY268G, GLY360C, GLY360G, GLY361C, GLY361G, GLY80C, GLY80G, HIS100C, HIS100G, HIS167C, HIS167G, HIS18C, HIS18G, HIS417C, HIS417G, HIS496G, ILE195C, ILE195G, ILE204C, ILE204G, LEU202C, LEU202G, LEU270C, LEU270G, LEU359C, LEU359G, LEU381C, LEU381G, LYS103C, LYS103G, LYS269C, LYS269G, MET358C, MET490C, MET490G, PHE165C, PHE165G, PRO196C, PRO196G, PRO207C, PRO385C, PRO385G, PRO81C, PRO81G, SER101C, SER101G, SER236C, SER236G, SER421C, SER421G, SER83C, SER83G, TRP271C, TRP271G, TRP82C, TRP82G, TYR102C, TYR102G, TYR237C, TYR237G, VAL265C, VAL265G, VAL266C, VAL266G
• C-H: ALA132H, ARG129H, ARG153H, ARG330C, ARG418C, ARG486C, ASN146H, ASN495C, ASP488C, CYS493C, GLN128H, GLN133H, GLN135H, GLN419C, GLU491C, HIS137H, HIS496C, ILE130H, ILE131H, LEU125H, LEU136H, LEU487C, LEU489C, LEU492C, LEU494C, MET490C, VAL134H
• D-E: ALA132E, ARG129E, ARG153E, ARG330D, ARG418D, ARG486D, ASN146E, ASN495D, ASP488D, CYS493D, GLN128E, GLN133E, GLN135E, GLN419D, GLU491D, HIS137E, HIS496D, ILE130E, ILE131E, LEU125E, LEU136E, LEU487D, LEU489D, LEU492D, LEU494D, MET490D, VAL134E
• D-F: ALA192D, ALA192F, ALA197D, ALA197F, ALA199D, ALA199F, ARG166D, ARG166F, ARG200D, ARG200F, ARG201D, ARG201F, ARG383D, ARG383F, ARG387D, ARG387F, ARG415D, ARG415F, ARG418D, ARG418F, ARG486D, ARG486F, ASN206D, ASN206F, ASN79D, ASP14D, ASP14F, ASP168D, ASP168F, ASP169D, ASP169F, ASP384D, ASP384F, ASP388D, ASP388F, CYS12D, GLN198D, GLN198F, GLN205D, GLN205F, GLN297F, GLN379F, GLN382D, GLN382F, GLN419D, GLN419F, GLU104D, GLU104F, GLU13D, GLU13F, GLU15D, GLU386D, GLU386F, GLU420D, GLU420F, GLY267D, GLY267F, GLY268D, GLY268F, GLY360D, GLY360F, GLY361D, GLY361F, GLY80D, GLY80F, HIS167D, HIS167F, HIS18D, HIS18F, HIS417D, HIS417F, HIS496F, ILE195D, ILE195F, ILE204D, ILE204F, LEU202D, LEU202F, LEU270D, LEU270F, LEU381D, LEU381F, LEU494F, LYS103D, LYS103F, LYS269D, LYS269F, MET490D, MET490F, PHE165D, PHE165F, PRO196D, PRO196F, PRO207D, PRO207F, PRO385D, PRO385F, PRO81D, PRO81F, SER421D, SER421F, TRP271D, TRP271F, TRP423F, TYR102D, TYR102F, TYR203D, TYR237D, TYR237F, VAL265D, VAL265F, VAL266D, VAL266F
• D-G: ALA132D, ALA497G, ARG129D, ARG153D, ARG330G, ARG418G, ARG486G, ASN126D, ASN146D, ASN495G, ASP488G, CYS493G, GLN128D, GLN133D, GLN135D, GLN419G, GLU491G, HIS137D, ILE130D, ILE131D, LEU125D, LEU136D, LEU487G, LEU489G, LEU492G, LEU494G, MET490G, VAL134D
• D-H: ALA141D, ALA141H, ALA175H, ALA324D, ALA324H, ALA332D, ALA332H, ALA338D, ALA338H, ALA340D, ALA340H, ALA347D, ALA347H, ALA355D, ALA355H, ALA374D, ARG129H, ARG153D, ARG153H, ARG159D, ARG159H, ARG178D, ARG178H, ARG179D, ARG179H, ARG327D, ARG327H, ARG328D, ARG328H, ARG362D, ARG362H, ARG367D, ARG367H, ARG372H, ARG434D, ARG434H, ARG436D, ARG436H, ARG457D, ASN146D, ASN146H, ASN376D, ASP139D, ASP139H, ASP149D, ASP149H, ASP181D, ASP181H, ASP331D, ASP331H, ASP333D, ASP333H, ASP334D, ASP334H, ASP343D, ASP343H, ASP344D, ASP344H, ASP353D, ASP353H, ASP369D, ASP369H, GLN133D, GLN133H, GLN188H, GLU172D, GLU172H, GLU176D, GLU176H, GLU180D, GLU180H, GLU183D, GLU183H, GLU371D, GLU371H, GLU442D, GLU464D, GLY187D, GLY187H, GLY337D, GLY337H, GLY345D, GLY345H, GLY354H, GLY360D, GLY360H, GLY361D, GLY361H, GLY368D, GLY368H, GLY375D, GLY438D, GLY438H, GLY439D, GLY439H, HIS137D, HIS137H, HIS341D, HIS341H, HIS429D, HIS433D, HIS433H, ILE346D, ILE346H, ILE366D, ILE366H, ILE435D, ILE435H, LEU136D, LEU136H, LEU143D, LEU143H, LEU182D, LEU182H, LEU186D, LEU186H, LEU323H, LEU335D, LEU335H, LEU339D, LEU339H, LEU356D, LEU356H, LEU359D, LEU359H, LEU364D, LEU364H, LEU378D, LYS440D, LYS440H, LYS443H, MET358D, MET358H, PHE336D, PHE336H, PHE370D, PHE370H, PHE460D, PRO342D, PRO342H, PRO441H, SER142D, SER142H, SER145D, SER145H, SER177D, SER177H, SER184D, SER184H, SER365D, SER365H, SER421D, THR140D, THR140H, THR363D, THR363H, TRP437D, TRP437H, TYR185H, VAL174D, VAL174H, VAL357D, VAL357H, VAL432D, VAL432H
• E-F: ALA127E, ALA127F, ALA132E, ALA132F, ALA301E, ALA301F, ALA312E, ALA312F, ALA324E, ALA324F, ALA326E, ALA326F, ALA329E, ALA332E, ALA480E, ARG113E, ARG113F, ARG129E, ARG129F, ARG289E, ARG289F, ARG305E, ARG305F, ARG310F, ARG316E, ARG316F, ARG321E, ARG321F, ARG322E, ARG322F, ARG327E, ARG327F, ARG328E, ARG328F, ARG330E, ARG330F, ARG70E, ASN126E, ASN126F, ASN138E, ASN138F, ASN495E, ASN495F, ASN84E, ASN84F, ASP116F, ASP139E, ASP139F, ASP331E, ASP331F, ASP333E, ASP488E, ASP488F, ASP96E, ASP96F, CYS299E, CYS299F, CYS493E, GLN128E, GLN128F, GLN133E, GLN133F, GLN135E, GLN135F, GLN293E, GLN293F, GLN297E, GLN297F, GLN308E, GLN308F, GLU304E, GLU304F, GLU307E, GLU307F, GLU313E, GLU313F, GLU320E, GLU320F, GLU491E, GLU491F, GLU67E, GLU74F, GLU87E, GLU87F, GLY267E, GLY267F, GLY309E, GLY309F, GLY99F, HIS100F, HIS137E, HIS137F, ILE120E, ILE120F, ILE130E, ILE130F, ILE131E, ILE131F, ILE208E, ILE264E, ILE294E, ILE294F, ILE302E, ILE302F, ILE311E, ILE311F, ILE98E, ILE98F, LEU118E, LEU118F, LEU125E, LEU125F, LEU136E, LEU136F, LEU143E, LEU143F, LEU306E, LEU306F, LEU314E, LEU315E, LEU315F, LEU323E, LEU323F, LEU325E, LEU325F, LEU485E, LEU485F, LEU487E, LEU487F, LEU489E, LEU489F, LEU492E, LEU492F, LYS484E, LYS484F, MET290E, MET290F, MET490E, MET490F, MET71E, MET71F, PHE123E, PHE123F, PHE292E, PHE292F, PHE295E, PHE295F, PRO207E, PRO207F, PRO285E, PRO287E, PRO287F, PRO81F, SER119E, SER119F, SER122E, SER122F, SER291E, SER291F, SER296E, SER296F, SER300E, SER300F, SER318E, SER318F, SER83E, SER83F, SER85E, SER85F, THR117E, THR117F, THR121E, THR121F, THR124E, THR124F, THR140E, THR140F, THR319E, THR319F, TRP82F, TYR286E, TYR286F, VAL134E, VAL134F, VAL265E, VAL265F, VAL266E, VAL266F, VAL288E, VAL288F, VAL298E, VAL298F, VAL303E, VAL303F, VAL317E, VAL317F, VAL86E, VAL86F, VAL97F
• E-G: ASN79G, GLU104G, GLU180E, GLU228G, GLY80G, LYS103G, LYS440E, PRO441E, THR229G
• F-H: ASN79F, ASP181H, GLU104F, GLU180H, GLU228F, GLU442H, GLY78F, GLY80F, LYS103F, LYS440H, LYS443H, PRO441H, THR229F
• G-H: ALA127G, ALA127H, ALA132G, ALA132H, ALA301G, ALA301H, ALA312G, ALA312H, ALA324G, ALA324H, ALA326G, ALA326H, ALA329G, ALA329H, ALA332G, ALA332H, ARG113G, ARG113H, ARG129G, ARG129H, ARG289G, ARG289H, ARG305G, ARG305H, ARG310G, ARG310H, ARG316G, ARG316H, ARG321G, ARG321H, ARG322G, ARG322H, ARG327G, ARG327H, ARG328G, ARG328H, ARG330G, ARG330H, ARG70H, ASN126G, ASN126H, ASN138G, ASN138H, ASN495G, ASN495H, ASN84G, ASN84H, ASP116G, ASP116H, ASP139G, ASP139H, ASP331G, ASP331H, ASP488G, ASP488H, ASP96H, CYS299G, CYS299H, GLN128G, GLN128H, GLN133G, GLN133H, GLN135G, GLN135H, GLN205G, GLN293G, GLN293H, GLN297G, GLN297H, GLN308G, GLN308H, GLU304G, GLU304H, GLU307H, GLU313G, GLU313H, GLU320G, GLU320H, GLU491G, GLU491H, GLU67H, GLU87H, GLY267G, GLY267H, GLY268H, GLY309G, GLY309H, GLY99G, HIS100G, HIS137G, HIS137H, HIS496H, ILE120G, ILE120H, ILE130G, ILE131G, ILE131H, ILE264H, ILE294G, ILE294H, ILE302G, ILE302H, ILE311G, ILE311H, ILE98G, ILE98H, LEU118G, LEU118H, LEU125G, LEU125H, LEU136G, LEU136H, LEU143G, LEU143H, LEU306G, LEU306H, LEU314G, LEU314H, LEU315G, LEU315H, LEU323G, LEU323H, LEU325G, LEU325H, LEU485G, LEU485H, LEU487G, LEU487H, LEU489G, LEU492G, LEU492H, LEU494H, LEU94H, LYS484G, LYS484H, MET290G, MET290H, MET490G, MET71G, PHE123G, PHE123H, PHE292G, PHE292H, PHE295G, PHE295H, PHE95H, PRO207G, PRO207H, PRO285H, PRO287G, PRO287H, PRO81G, SER119G, SER119H, SER122G, SER122H, SER142G, SER291G, SER291H, SER296G, SER296H, SER300G, SER300H, SER318G, SER318H, SER83G, SER83H, SER85G, SER85H, THR117G, THR117H, THR121G, THR121H, THR124G, THR124H, THR140G, THR140H, THR319G, THR319H, THR88H, TRP82G, TYR286G, TYR286H, VAL134G, VAL134H, VAL265G, VAL265H, VAL266G, VAL266H, VAL288G, VAL288H, VAL298G, VAL298H, VAL303G, VAL303H, VAL317G, VAL317H, VAL86G, VAL86H, VAL97G, VAL97H