3NH7

crystal structure of the neutralizing fab fragment abd1556 bound to the bmp type i receptor ia

• Total interactions analyzed: 66
• Total true interactions: 26
• Strongest Interaction:
  • Chains: K-D
  • Int. Res.: 78
  • Norm. En. per Res.: -4.873
• Hub Node: J(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
H-L	-22.2261	-36.6826	-412.613	-471.5217	179	16	15	17558	1	16	20
H-A	-63.9511	-98.3953	-187.364	-349.7103	80	25	1	8800	9	25	27
H-I	0.0	0.0	-1.3057	-1.3057	11	0	0	168	0	2	0
L-A	-36.4805	-20.017	41.0799	-15.4176	57	21	0	3162	2	11	13
L-I	-15.0236	0.0	-73.5312	-88.5548	49	11	0	3680	0	6	6
L-K	0.0	0.0	-24.5643	-24.5643	39	0	0	1334	0	1	1
L-D	0.0	0.0	-0.0096	-0.0096	2	0	0	10	0	0	0
A-I	0.0	0.0	-1.1493	-1.1493	17	0	0	225	0	3	3
I-M	-21.5629	-41.2863	-453.083	-515.9322	179	7	15	17998	2	17	21
I-B	-52.2423	-87.2636	-183.441	-322.9469	80	27	1	8458	9	27	27
I-K	-4.805	9.0504	-44.1582	-39.9129	32	3	0	2044	0	14	15
I-O	0.0	0.0	-0.0034	-0.0034	2	0	0	2	0	0	0
M-B	-32.821	-19.7353	-4.3544	-56.9108	56	20	0	3069	2	11	13
M-K	0.0	0.0	-0.0033	-0.0033	2	0	0	2	0	0	0
M-O	0.0	0.0	-2.2165	-2.2165	22	0	0	370	0	4	3
M-D	-45.156	28.364	-104.04	-120.8321	45	11	0	3799	0	20	15
B-O	-41.4268	27.4618	-97.4825	-111.4475	45	9	0	3641	0	20	15
J-N	-24.8799	-46.0066	-449.078	-519.9645	189	8	15	18690	2	20	23
J-C	-54.0625	-93.7227	-179.291	-327.0763	80	20	1	8215	9	26	27
J-K	0.0	0.0	-0.5388	-0.5388	12	0	0	118	0	2	0
J-O	-10.393	0.0	-77.2792	-87.6722	47	5	0	3519	0	6	6
J-D	0.0	0.0	-1.2972	-1.2972	14	0	0	237	0	3	3
N-C	-31.7741	-20.3528	-42.8485	-94.9754	53	13	0	2753	2	10	14
K-O	-26.0744	-42.6462	-460.887	-529.6076	183	16	15	18349	2	19	21
K-D	-49.2913	-137.773	-193.029	-380.0933	78	24	1	8490	9	27	27
O-D	-35.7426	-17.1782	-71.0769	-123.9977	58	22	0	3100	2	10	13

Interface residues

• H-L: ALA129L, ALA132H, ALA132L, ALA143H, ALA144H, ALA175H, ALA175L, ALA176L, ALA40H, ALA42L, ALA61H, ALA97H, ARG100H, ARG104H, ARG38H, ARG98H, ASN171L, ASN35H, ASN52L, ASN95L, ASP108H, ASP140L, ASP151H, ASP49L, ASP50L, ASP62H, ASP84L, CYS136L, CYS147H, CYS87L, CYS96H, GLN112H, GLN169L, GLN178H, GLN36L, GLN37L, GLN39H, GLN41L, GLU125L, GLU126L, GLU162L, GLU46H, GLU6H, GLU99H, GLY100L, GLY101L, GLY102L, GLY105H, GLY111H, GLY113H, GLY146H, GLY160L, GLY181H, GLY40L, GLY42H, GLY44H, GLY59H, GLY94L, GLY96L, HIS102H, HIS109H, HIS171H, ILE138L, ILE33L, ILE47L, LEU119L, LEU127L, LEU131H, LEU134L, LEU137L, LEU145H, LEU148H, LEU177H, LEU180L, LEU182H, LEU182L, LEU185H, LEU45H, LEU45L, LEU57H, LYS131L, LYS150H, LYS168L, LYS173L, LYS216H, LYS217H, LYS30L, LYS38L, LYS43H, LYS65H, MET92L, PHE107H, PHE120L, PHE129H, PHE141L, PHE173H, PHE90L, PHE99L, PRO121L, PRO122L, PRO130H, PRO133H, PRO166L, PRO174H, PRO39L, PRO41H, PRO43L, PRO54L, SER116L, SER123L, SER124L, SER127H, SER134H, SER139L, SER167L, SER170L, SER177L, SER178L, SER179H, SER180H, SER181L, SER184H, SER186H, SER187H, SER29L, SER49H, SER55L, SER63H, SER88L, SER93L, THR118L, THR133L, THR163L, THR164L, THR165L, THR172H, THR190H, THR33H, THR58H, THR89L, THR91L, THR97L, TRP101H, TRP110H, TRP34L, TRP36H, TRP47H, TYR106H, TYR152H, TYR174L, TYR179L, TYR183H, TYR31L, TYR35L, TYR48L, TYR50H, TYR60H, TYR85L, TYR86L, TYR95H, VAL103H, VAL117L, VAL128H, VAL135L, VAL149H, VAL161L, VAL170H, VAL176H, VAL188H, VAL189H, VAL208L, VAL218H, VAL32L, VAL37H, VAL44L, VAL46L, VAL48H, VAL93H, VAL98L
• H-A: ALA61A, ALA74A, ALA93A, ARG100H, ARG104H, ARG72H, ARG96A, ARG97A, ARG98H, ASN31H, ASN35H, ASN74H, ASP108H, ASP66A, ASP67A, ASP84A, ASP89A, CYS101A, CYS77A, CYS87A, GLN1H, GLN68A, GLN86A, GLN94A, GLU64A, GLU65A, GLU70A, GLU81A, GLU99H, GLY105H, GLY26H, GLY42A, GLY59H, GLY76A, HIS102H, HIS109H, HIS43A, HIS58A, ILE62A, ILE63A, ILE99A, LEU34H, LEU57H, LEU73A, LEU95A, LYS79A, LYS88A, LYS92A, MET78A, PHE107H, PHE27H, PHE29H, PHE60A, PHE85A, PRO116A, PRO91A, SER30H, SER41A, SER49H, SER52H, SER53H, SER54H, SER56H, SER75A, SER90A, THR28H, THR33H, THR51H, THR58H, THR71A, THR72A, TRP101H, TRP47H, TYR106H, TYR32H, TYR50H, TYR80A, VAL103H, VAL118A, VAL2H
• H-I: ASN211I, GLN112H, GLN1H, GLY10I, LEU115H, PHE153I, PRO154I, PRO209I, SER122I, SER210I, THR123I
• L-A: ALA70L, ALA74A, ARG53L, ASN52L, ASN56A, ASN65L, ASN95L, ASP46A, ASP49L, ASP50L, ASP84A, ASP89A, CYS44A, CYS77A, GLN86A, GLU64A, GLU81A, GLY28L, GLY42A, GLY57A, GLY63L, GLY67L, GLY82A, GLY94L, GLY96L, HIS43A, HIS58A, ILE47L, ILE62A, ILE99A, LEU27L, LYS30L, LYS79A, LYS92A, MET78A, MET92L, PHE60A, PHE85A, PHE90L, PRO45A, PRO91A, SER26L, SER29L, SER51L, SER62L, SER64L, SER66L, SER83A, SER90A, THR55A, THR89L, THR91L, THR97L, TYR31L, TYR48L, TYR80A, VAL32L
• L-I: ALA121I, ALA42L, ARG19I, ARG53L, ARG60L, ASN211I, ASN84I, ASP81L, GLN13I, GLN36L, GLN41L, GLN78L, GLN82I, GLU59L, GLU80L, GLY125I, GLY15I, GLY16I, GLY40L, GLY56L, GLY8I, ILE57L, LEU11I, LEU18I, LEU86I, LYS124I, LYS38L, MET83I, PHE153I, PHE61L, PRO14I, PRO154I, PRO209I, PRO39L, PRO54L, PRO58L, SER119I, SER120I, SER122I, SER17I, SER210I, SER55L, SER85I, THR123I, TYR85L, VAL118I, VAL12I, VAL44L, VAL46L
• L-K: ALA13L, ALA79L, ARG19K, ARG60L, ARG72K, ASN74K, ASN84K, ASP73K, GLN110L, GLN16L, GLN78L, GLN82K, GLU59L, GLY109L, GLY15L, GLY55K, GLY76L, ILE70K, LEU108L, LEU57K, LYS76K, PHE29K, PRO111L, PRO14L, SER52K, SER53K, SER54K, SER56K, SER71K, SER75K, SER75L, THR17L, THR51K, THR58K, THR69K, THR77L, TYR60K, TYR80K, VAL107L
• L-D: PRO111L, VAL118D
• A-I: ALA23I, ARG19I, ASP66A, GLN68A, GLU70A, GLY10I, GLY8I, GLY9I, LEU73A, LYS76I, SER21I, SER7I, THR114I, THR71A, THR72A, THR78I, TYR80I
• I-M: ALA129M, ALA132I, ALA132M, ALA143I, ALA144I, ALA175I, ALA175M, ALA176M, ALA40I, ALA42M, ALA61I, ALA97I, ARG100I, ARG104I, ARG38I, ARG98I, ASN171M, ASN35I, ASN52M, ASN95M, ASP108I, ASP140M, ASP151I, ASP49M, ASP50M, ASP62I, ASP84M, CYS136M, CYS147I, CYS87M, CYS96I, GLN112I, GLN128M, GLN169M, GLN178I, GLN36M, GLN37M, GLN39I, GLN41M, GLU125M, GLU126M, GLU162M, GLU46I, GLU6I, GLU99I, GLY100M, GLY101M, GLY102M, GLY105I, GLY111I, GLY113I, GLY146I, GLY160M, GLY181I, GLY40M, GLY42I, GLY44I, GLY59I, GLY94M, GLY96M, HIS102I, HIS109I, HIS171I, ILE138M, ILE33M, ILE47M, LEU119M, LEU127M, LEU131I, LEU134M, LEU137M, LEU145I, LEU148I, LEU177I, LEU180M, LEU182I, LEU182M, LEU185I, LEU45I, LEU45M, LEU57I, LYS124I, LYS131M, LYS150I, LYS168M, LYS173M, LYS216I, LYS217I, LYS30M, LYS38M, LYS43I, LYS65I, MET92M, PHE107I, PHE120M, PHE129I, PHE141M, PHE173I, PHE90M, PHE99M, PRO121M, PRO122M, PRO130I, PRO133I, PRO166M, PRO174I, PRO39M, PRO41I, PRO43M, PRO54M, SER116M, SER123M, SER124M, SER127I, SER134I, SER139M, SER167M, SER170M, SER177M, SER178M, SER179I, SER180I, SER181M, SER184I, SER186I, SER187I, SER29M, SER49I, SER51M, SER55M, SER88M, SER93M, THR118M, THR133M, THR163M, THR164M, THR165M, THR172I, THR190I, THR58I, THR89M, THR91M, THR97M, TRP101I, TRP110I, TRP34M, TRP36I, TRP47I, TYR106I, TYR174M, TYR179M, TYR183I, TYR31M, TYR35M, TYR48M, TYR50I, TYR60I, TYR85M, TYR86M, TYR95I, VAL103I, VAL117M, VAL128I, VAL135M, VAL149I, VAL161M, VAL176I, VAL188I, VAL189I, VAL208M, VAL214I, VAL218I, VAL32M, VAL37I, VAL44M, VAL46M, VAL48I, VAL93I, VAL98M
• I-B: ALA74B, ALA93B, ARG100I, ARG104I, ARG72I, ARG96B, ARG97B, ARG98I, ASN31I, ASN35I, ASN74I, ASP108I, ASP66B, ASP67B, ASP84B, ASP89B, CYS101B, CYS77B, CYS87B, GLN1I, GLN68B, GLN86B, GLN94B, GLU64B, GLU65B, GLU70B, GLU81B, GLU99I, GLY105I, GLY26I, GLY42B, GLY55I, GLY59I, GLY76B, HIS102I, HIS109I, HIS43B, HIS58B, ILE62B, ILE63B, ILE99B, LEU34I, LEU57I, LEU73B, LEU95B, LYS79B, LYS88B, LYS92B, MET78B, PHE107I, PHE27I, PHE29I, PHE60B, PHE85B, PRO116B, PRO91B, SER30I, SER41B, SER49I, SER52I, SER53I, SER54I, SER56I, SER75B, SER90B, THR28I, THR33I, THR51I, THR58I, THR71B, THR72B, TRP101I, TRP47I, TYR106I, TYR32I, TYR50I, TYR80B, VAL103I, VAL118B, VAL2I
• I-K: ALA61I, ALA61K, ARG67I, ARG67K, ARG87I, ARG87K, ASN84I, ASN84K, ASP62I, ASP62K, GLU89I, GLU89K, GLY15I, GLY15K, GLY66I, GLY66K, LEU86I, LEU86K, LYS65I, LYS65K, PHE68I, PHE68K, SER63I, SER63K, SER85I, SER85K, THR69I, THR69K, TYR60I, TYR60K, VAL64I, VAL64K
• I-O: ARG104I, GLU185O
• M-B: ALA70M, ALA74B, ARG53M, ASN52M, ASN56B, ASN65M, ASN95M, ASP46B, ASP49M, ASP50M, ASP84B, CYS44B, CYS77B, GLN86B, GLU64B, GLU81B, GLY28M, GLY42B, GLY57B, GLY63M, GLY67M, GLY82B, GLY94M, GLY96M, HIS43B, HIS58B, ILE47M, ILE62B, LEU27M, LYS30M, LYS79B, LYS92B, MET78B, MET92M, PHE60B, PHE85B, PHE90M, PRO45B, PRO91B, SER26M, SER29M, SER51M, SER62M, SER64M, SER66M, SER83B, SER90B, THR55B, THR72B, THR89M, THR91M, THR97M, TYR31M, TYR48M, TYR80B, VAL32M
• M-K: ARG104K, GLU185M
• M-O: ALA159M, ALA159O, ASN95M, ASN95O, GLN186M, GLN186O, GLY160M, GLY160O, ILE2M, ILE2O, LYS158M, LYS158O, MET92M, MET92O, PRO156M, PRO156O, SER155M, SER155O, SER26M, SER26O, SER29M, SER29O
• M-D: ALA152M, ALA159M, ARG103D, ARG191M, ASN130M, ASN56D, ASP153M, ASP84D, ASP89D, CYS101D, CYS87D, GLN186M, GLN86D, GLU100D, GLU185M, GLU81D, GLY57D, GLY82D, HIS190M, HIS58D, ILE99D, LEU180M, LEU182M, LYS151M, LYS158M, LYS188M, LYS88D, PHE35D, PHE85D, PRO156M, PRO184M, PRO210M, PRO91D, SER154M, SER155M, SER189M, SER192M, SER83D, SER90D, THR183M, TRP150M, TRP187M, TYR193M, TYR80D, VAL157M
• B-O: ALA152O, ALA159O, ARG103B, ARG191O, ASN130O, ASN56B, ASP153O, ASP84B, ASP89B, CYS101B, CYS87B, GLN186O, GLN86B, GLU100B, GLU185O, GLU81B, GLY57B, GLY82B, HIS190O, HIS58B, ILE99B, LEU180O, LEU182O, LYS151O, LYS158O, LYS188O, LYS88B, PHE35B, PHE85B, PRO156O, PRO184O, PRO210O, PRO91B, SER154O, SER155O, SER189O, SER192O, SER83B, SER90B, THR183O, TRP150O, TRP187O, TYR193O, TYR80B, VAL157O
• J-N: ALA129N, ALA132J, ALA132N, ALA143J, ALA144J, ALA175J, ALA175N, ALA176N, ALA209N, ALA40J, ALA42N, ALA61J, ALA97J, ARG100J, ARG104J, ARG38J, ARG98J, ASN130N, ASN171N, ASN35J, ASN52N, ASN95N, ASP108J, ASP140N, ASP151J, ASP49N, ASP50N, ASP62J, ASP84N, CYS136N, CYS147J, CYS87N, CYS96J, GLN112J, GLN128N, GLN169N, GLN178J, GLN36N, GLN37N, GLN39J, GLN41N, GLU125N, GLU126N, GLU162N, GLU46J, GLU6J, GLU99J, GLY100N, GLY101N, GLY102N, GLY105J, GLY111J, GLY113J, GLY146J, GLY160N, GLY181J, GLY40N, GLY42J, GLY44J, GLY59J, GLY94N, GLY96N, HIS102J, HIS109J, HIS171J, ILE138N, ILE33N, ILE47N, LEU119N, LEU127N, LEU131J, LEU134N, LEU137N, LEU145J, LEU148J, LEU177J, LEU180N, LEU182J, LEU182N, LEU185J, LEU45J, LEU45N, LEU57J, LYS131N, LYS136J, LYS150J, LYS168N, LYS173N, LYS206N, LYS216J, LYS217J, LYS221J, LYS30N, LYS38N, LYS43J, LYS65J, MET92N, PHE107J, PHE120N, PHE129J, PHE141N, PHE173J, PHE90N, PHE99N, PRO121N, PRO122N, PRO130J, PRO133J, PRO166N, PRO174J, PRO210N, PRO39N, PRO41J, PRO43N, PRO54N, SER116N, SER123N, SER124N, SER127J, SER134J, SER137J, SER139J, SER139N, SER167N, SER170N, SER177N, SER178N, SER179J, SER180J, SER181N, SER184J, SER186J, SER187J, SER29N, SER49J, SER55N, SER88N, SER93N, THR118N, THR133N, THR138J, THR163N, THR164N, THR165N, THR172J, THR190J, THR207N, THR211N, THR58J, THR89N, THR91N, THR97N, TRP101J, TRP110J, TRP187N, TRP34N, TRP36J, TRP47J, TYR106J, TYR174N, TYR179N, TYR183J, TYR31N, TYR35N, TYR48N, TYR50J, TYR60J, TYR85N, TYR86N, TYR95J, VAL103J, VAL117N, VAL128J, VAL135N, VAL149J, VAL161N, VAL176J, VAL188J, VAL189J, VAL208N, VAL214J, VAL218J, VAL32N, VAL37J, VAL44N, VAL46N, VAL48J, VAL93J, VAL98N
• J-C: ALA74C, ALA93C, ARG100J, ARG104J, ARG72J, ARG96C, ARG97C, ARG98J, ASN31J, ASN35J, ASN74J, ASP108J, ASP66C, ASP67C, ASP84C, ASP89C, CYS101C, CYS77C, CYS87C, GLN1J, GLN68C, GLN86C, GLN94C, GLU64C, GLU65C, GLU70C, GLU81C, GLU99J, GLY105J, GLY26J, GLY42C, GLY55J, GLY59J, GLY76C, HIS102J, HIS109J, HIS43C, HIS58C, ILE62C, ILE63C, ILE99C, LEU34J, LEU57J, LEU73C, LEU95C, LYS79C, LYS88C, LYS92C, MET78C, PHE107J, PHE27J, PHE29J, PHE60C, PHE85C, PRO116C, PRO91C, SER30J, SER41C, SER49J, SER52J, SER53J, SER54J, SER56J, SER75C, SER90C, THR28J, THR33J, THR51J, THR58J, THR71C, THR72C, TRP101J, TRP47J, TYR106J, TYR32J, TYR50J, TYR80C, VAL103J, VAL118C, VAL2J
• J-K: ASN211J, GLN112K, GLN1K, GLY10J, GLY9J, LEU115K, LEU11J, PHE153J, PRO154J, PRO209J, SER122J, THR123J
• J-O: ALA121J, ALA42O, ARG19J, ARG53O, ARG60O, ASN84J, ASP81O, GLN13J, GLN36O, GLN41O, GLN78O, GLN82J, GLU59O, GLU80O, GLY15J, GLY16J, GLY40O, GLY56O, GLY8J, ILE57O, LEU11J, LEU18J, LEU86J, LYS124J, LYS38O, MET83J, PHE153J, PHE61O, PRO14J, PRO154J, PRO209J, PRO39O, PRO54O, PRO58O, SER119J, SER120J, SER122J, SER17J, SER210J, SER55O, SER85J, THR123J, TYR85O, VAL118J, VAL12J, VAL44O, VAL46O
• J-D: ARG19J, GLN68D, GLU70D, GLY8J, GLY9J, LEU73D, LYS76J, SER21J, SER7J, THR114J, THR71D, THR72D, THR78J, TYR80J
• N-C: ALA70N, ALA74C, ARG53N, ASN52N, ASN56C, ASN65N, ASN95N, ASP46C, ASP49N, ASP50N, ASP84C, CYS44C, CYS77C, GLN86C, GLU64C, GLU81C, GLY28N, GLY42C, GLY57C, GLY63N, GLY67N, GLY82C, GLY94N, GLY96N, HIS43C, HIS58C, ILE47N, ILE62C, LEU27N, LYS30N, LYS79C, LYS92C, MET78C, MET92N, PHE60C, PHE85C, PHE90N, PRO45C, PRO91C, SER26N, SER29N, SER51N, SER62N, SER64N, SER66N, SER83C, SER90C, THR91N, THR97N, TYR31N, TYR48N, TYR80C, VAL32N
• K-O: ALA129O, ALA132K, ALA132O, ALA143K, ALA144K, ALA175K, ALA175O, ALA176O, ALA40K, ALA42O, ALA61K, ALA97K, ARG100K, ARG104K, ARG38K, ARG98K, ASN130O, ASN171O, ASN35K, ASN52O, ASN95O, ASP108K, ASP140O, ASP151K, ASP49O, ASP50O, ASP62K, ASP84O, CYS136O, CYS147K, CYS87O, CYS96K, GLN112K, GLN128O, GLN169O, GLN178K, GLN36O, GLN37O, GLN39K, GLN41O, GLU125O, GLU126O, GLU162O, GLU46K, GLU6K, GLU99K, GLY100O, GLY101O, GLY102O, GLY105K, GLY111K, GLY113K, GLY146K, GLY160O, GLY181K, GLY40O, GLY42K, GLY44K, GLY59K, GLY94O, GLY96O, HIS102K, HIS109K, HIS171K, ILE138O, ILE33O, ILE47O, LEU119O, LEU127O, LEU131K, LEU134O, LEU137O, LEU145K, LEU148K, LEU177K, LEU180O, LEU182K, LEU182O, LEU185K, LEU45K, LEU45O, LEU57K, LYS124K, LYS131O, LYS150K, LYS168O, LYS173O, LYS216K, LYS217K, LYS221K, LYS30O, LYS43K, LYS65K, MET92O, PHE107K, PHE120O, PHE129K, PHE141O, PHE173K, PHE90O, PHE99O, PRO121O, PRO122O, PRO130K, PRO133K, PRO166O, PRO174K, PRO39O, PRO41K, PRO43O, PRO54O, SER116O, SER123O, SER124O, SER127K, SER134K, SER139O, SER167O, SER170O, SER177O, SER178O, SER179K, SER180K, SER181O, SER184K, SER186K, SER187K, SER29O, SER49K, SER51O, SER55O, SER63K, SER88O, SER93O, THR118O, THR133O, THR163O, THR164O, THR165O, THR172K, THR190K, THR207O, THR58K, THR89O, THR91O, THR97O, TRP101K, TRP110K, TRP34O, TRP36K, TRP47K, TYR106K, TYR152K, TYR174O, TYR179O, TYR183K, TYR31O, TYR35O, TYR48O, TYR50K, TYR60K, TYR85O, TYR86O, TYR95K, VAL103K, VAL117O, VAL128K, VAL135O, VAL149K, VAL161O, VAL176K, VAL188K, VAL189K, VAL208O, VAL214K, VAL218K, VAL32O, VAL37K, VAL44O, VAL46O, VAL48K, VAL93K, VAL98O
• K-D: ALA74D, ALA93D, ARG100K, ARG104K, ARG72K, ARG96D, ARG97D, ARG98K, ASN31K, ASN35K, ASN74K, ASP108K, ASP66D, ASP67D, ASP84D, ASP89D, CYS101D, CYS77D, CYS87D, GLN1K, GLN68D, GLN86D, GLN94D, GLU64D, GLU65D, GLU70D, GLU81D, GLU99K, GLY105K, GLY26K, GLY42D, GLY59K, GLY76D, HIS102K, HIS109K, HIS43D, HIS58D, ILE62D, ILE63D, ILE99D, LEU34K, LEU57K, LEU73D, LEU95D, LYS79D, LYS88D, LYS92D, MET78D, PHE107K, PHE27K, PHE29K, PHE60D, PHE85D, PRO116D, PRO91D, SER30K, SER41D, SER49K, SER52K, SER53K, SER54K, SER56K, SER75D, SER90D, THR28K, THR33K, THR51K, THR58K, THR71D, THR72D, TRP101K, TRP47K, TYR106K, TYR32K, TYR50K, VAL103K, VAL118D, VAL2K
• O-D: ALA70O, ALA74D, ARG53O, ARG97D, ASN52O, ASN56D, ASN65O, ASN95O, ASP46D, ASP49O, ASP50O, ASP84D, ASP89D, CYS44D, CYS77D, GLN86D, GLU64D, GLU81D, GLY28O, GLY42D, GLY57D, GLY63O, GLY67O, GLY82D, GLY94O, GLY96O, HIS43D, HIS58D, ILE47O, ILE62D, ILE99D, LEU27O, LYS30O, LYS79D, LYS92D, MET78D, MET92O, PHE60D, PHE85D, PHE90O, PRO45D, PRO91D, SER26O, SER29O, SER51O, SER62O, SER64O, SER66O, SER83D, SER90D, THR55D, THR89O, THR91O, THR97O, TYR31O, TYR48O, TYR80D, VAL32O