3NGT

structure of leishmania ndkb complexed with amp.

• Total interactions analyzed: 91
• Total true interactions: 29
• Strongest Interaction:
  • Chains: G-I
  • Int. Res.: 71
  • Norm. En. per Res.: -4.2387
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-68.956	12.8532	-267.327	-323.4298	105	15	20	10792	0	20	24
A-C	-25.1858	-65.014	-187.807	-278.0069	76	4	2	7843	4	25	24
A-E	-47.2157	-39.5919	-188.396	-275.2035	73	9	2	7949	1	25	24
A-F	-14.6078	8.7358	-36.5865	-42.4585	17	8	0	1077	0	3	3
A-K	0.0	0.0	-0.0822	-0.0822	8	0	0	49	0	4	6
B-D	-36.6929	-51.7248	-191.827	-280.2447	76	5	2	7692	1	26	24
B-E	-8.7516	8.8768	-45.6109	-45.4857	18	6	0	1126	0	4	2
B-F	-42.331	-30.4612	-183.103	-255.8953	73	5	2	7808	0	26	23
B-J	0.0	-26.0152	-8.9184	-34.9337	29	1	0	939	1	6	7
B-K	0.0	18.0277	-23.9605	-5.9328	20	1	0	999	0	8	7
C-D	-9.7004	8.1774	-41.4622	-42.9852	18	5	0	1085	0	4	2
C-E	-47.7396	-35.9836	-185.231	-268.9542	69	6	2	7489	2	24	23
C-F	-82.9887	5.2008	-267.943	-345.7309	103	17	19	11014	0	20	23
D-E	-85.5422	-3.9766	-275.195	-364.7139	105	12	19	11111	0	20	24
D-F	-25.3307	-35.4901	-186.823	-247.6438	73	6	2	7705	1	27	24
D-N	-18.1124	0.0	-88.9476	-107.06	40	7	0	3380	0	6	7
G-H	-59.4716	3.9895	-260.717	-316.1991	102	12	20	10937	0	21	25
G-I	-60.7994	-41.6265	-198.522	-300.9479	71	7	2	7769	2	25	24
G-K	-75.9874	-33.6111	-193.501	-303.0995	73	10	2	7419	2	24	23
G-L	-16.4472	8.5964	-43.5628	-51.4136	18	6	0	1088	0	2	4
H-J	-37.6805	-29.812	-183.974	-251.4665	75	4	2	7337	0	26	23
H-K	-13.7845	8.5724	-45.3741	-50.5862	20	6	0	1114	0	4	2
H-L	-33.4022	-29.5017	-167.203	-230.107	70	5	2	7094	0	19	21
I-J	-15.8571	9.2444	-35.1564	-41.7691	18	5	0	1091	0	3	2
I-K	-51.3873	-47.1359	-191.63	-290.1532	75	11	2	7729	3	25	23
I-L	-66.4523	13.9716	-256.879	-309.3597	106	11	20	10983	0	21	25
J-K	-71.9769	-3.74	-272.102	-347.8189	104	17	20	11083	0	20	24
J-L	-28.5967	-30.9145	-164.772	-224.2833	70	6	1	7102	0	20	21
M-N	-71.9843	-5.7387	-261.992	-339.715	105	11	19	10747	0	21	24

Interface residues

• A-B: ALA139A, ALA139B, ALA25A, ALA25B, ALA36A, ALA36B, ARG17A, ARG17B, ARG26A, ARG26B, ARG29A, ARG29B, ASP136A, ASP136B, ASP13A, ASP13B, CYS74A, CYS74B, GLN16A, GLN16B, GLN41A, GLN41B, GLU137A, GLU137B, GLU22A, GLU22B, GLU28A, GLU28B, GLY14A, GLY14B, GLY18A, GLY18B, GLY21A, GLY21B, GLY31A, GLY31B, GLY70A, GLY70B, HIS144A, HIS144B, ILE138A, ILE138B, ILE149A, ILE23A, ILE23B, ILE24A, ILE24B, ILE39A, ILE39B, ILE72A, ILE72B, LEU19A, LEU19B, LEU34A, LEU34B, LEU37A, LEU37B, LEU40A, LEU40B, LYS134A, LYS134B, LYS33A, LYS33B, LYS38A, LYS38B, MET75A, MET75B, PHE133A, PHE133B, PHE27A, PHE27B, PRO12A, PRO12B, PRO71A, PRO71B, SER140A, SER140B, SER143A, SER143B, SER145A, SER145B, SER69A, SER69B, THR142A, THR142B, TRP141A, TRP141B, TRP77A, TRP77B, TYR32A, TYR32B, VAL10A, VAL10B, VAL146A, VAL146B, VAL15A, VAL15B, VAL20A, VAL20B, VAL35A, VAL35B, VAL73A, VAL73B, VAL76A, VAL76B
• A-C: ALA108C, ALA25A, ALA62C, ALA92A, ALA96C, ARG104C, ARG113C, ARG17C, ARG26A, ARG26C, ARG29A, ARG29C, ARG87A, ASN114C, ASN81A, ASN94C, ASP106A, ASP106C, ASP110C, ASP13C, ASP97C, GLN148A, GLN16C, GLN99A, GLN99C, GLU151A, GLU22C, GLU28A, GLU78A, GLY101A, GLY101C, GLY105A, GLY105C, GLY112C, GLY14C, GLY18C, GLY31A, GLY79A, GLY91A, HIS144A, ILE103A, ILE103C, ILE149A, LEU19C, LEU63C, LEU89A, LEU90A, LYS30A, LYS65C, LYS80A, LYS84A, PHE107C, PHE27A, PHE59C, PRO100A, PRO100C, PRO12C, PRO95C, SER145A, SER147A, SER2A, SER85A, SER98A, SER98C, THR102A, THR102C, TYR150A, TYR32A, TYR66C, VAL109C, VAL111C, VAL115C, VAL146A, VAL15C, VAL82A, VAL88A
• A-E: ALA108A, ALA25E, ALA62A, ALA92E, ALA96A, ARG104A, ARG113A, ARG17A, ARG26A, ARG26E, ARG29E, ARG87E, ASN114A, ASN81E, ASN94A, ASP106A, ASP106E, ASP110A, ASP13A, ASP97A, GLN148E, GLN16A, GLN99A, GLN99E, GLU151E, GLU22A, GLU28E, GLU78E, GLY101A, GLY101E, GLY105A, GLY105E, GLY112A, GLY14A, GLY31E, GLY79E, GLY91E, HIS144E, ILE103A, ILE103E, ILE149E, LEU19A, LEU63A, LEU89E, LEU90E, LYS30E, LYS80E, LYS84E, PHE107A, PHE27E, PHE59A, PRO100A, PRO100E, PRO12A, PRO95A, SER145E, SER147E, SER2E, SER85E, SER98A, SER98E, THR102A, THR102E, TYR150E, TYR32E, TYR66A, VAL109A, VAL111A, VAL115A, VAL146E, VAL15A, VAL82E, VAL88E
• A-F: GLN148A, GLN148F, HIS144A, HIS144F, ILE149A, ILE149F, SER143A, SER143F, SER145A, SER145F, SER147A, SER147F, THR142A, THR142F, TRP141A, VAL146A, VAL146F
• A-K: ALA135K, ARG5K, ASP136A, GLN46A, GLU126K, LYS134A, SER3K, THR43A
• B-D: ALA108D, ALA25B, ALA62D, ALA92B, ALA96D, ARG104D, ARG113D, ARG17D, ARG26B, ARG26D, ARG29B, ARG87B, ASN114D, ASN81B, ASN94D, ASP106B, ASP106D, ASP110D, ASP13D, ASP97D, GLN148B, GLN16D, GLN99B, GLN99D, GLU151B, GLU22D, GLU28B, GLU78B, GLY101B, GLY101D, GLY105B, GLY105D, GLY112D, GLY14D, GLY18D, GLY31B, GLY79B, GLY86B, GLY91B, HIS144B, ILE103B, ILE103D, ILE149B, LEU19D, LEU63D, LEU89B, LEU90B, LYS30B, LYS33B, LYS65D, LYS80B, LYS84B, PHE107D, PHE27B, PHE59D, PRO100B, PRO100D, PRO12D, PRO95D, SER145B, SER147B, SER69D, SER85B, SER98D, THR102B, THR102D, TYR150B, TYR32B, TYR66D, VAL109D, VAL111D, VAL115D, VAL146B, VAL15D, VAL82B, VAL88B
• B-E: GLN148B, GLN148E, HIS144B, HIS144E, ILE149B, ILE149E, SER143B, SER143E, SER145B, SER145E, SER147B, SER147E, THR142B, THR142E, TRP141B, TRP141E, VAL146B, VAL146E
• B-F: ALA108B, ALA25F, ALA62B, ALA96B, ARG104B, ARG113B, ARG17B, ARG26B, ARG26F, ARG29F, ARG87F, ASN114B, ASN81F, ASN94B, ASP106B, ASP106F, ASP110B, ASP13B, ASP97B, GLN148F, GLN16B, GLN99B, GLN99F, GLU151F, GLU22B, GLU28F, GLU78F, GLY101B, GLY101F, GLY105B, GLY105F, GLY112B, GLY14B, GLY31F, GLY79F, GLY91F, HIS144F, ILE103B, ILE103F, ILE149F, LEU19B, LEU63B, LEU89F, LEU90F, LYS30F, LYS33F, LYS80F, LYS84F, PHE107B, PHE27F, PHE59B, PRO100B, PRO100F, PRO12B, PRO95B, SER145F, SER147F, SER2F, SER69B, SER85F, SER98B, THR102B, THR102F, TYR150F, TYR32F, TYR66B, VAL109B, VAL111B, VAL115B, VAL146F, VAL15B, VAL82F, VAL88F
• B-J: ALA130B, ALA135B, ARG127B, ARG5B, ASP53B, GLN41J, GLN46J, GLN48J, GLU123B, GLU126B, GLU45J, GLY49B, GLY70J, ILE129B, LYS134B, LYS52B, LYS65J, PHE131B, PHE133B, PRO42J, PRO61J, PRO71J, SER124B, SER68J, SER69J, THR43J, THR44J, VAL122B, VAL64J
• B-K: ALA135B, ALA135K, ALA139K, ARG5K, ASP136B, ASP136K, GLU137B, GLU78K, ILE138B, ILE138K, LYS134B, LYS33K, PHE133B, SER140B, SER140K, SER143K, SER3K, THR142K, TRP141K, VAL35K
• C-D: GLN148C, GLN148D, HIS144C, HIS144D, ILE149C, ILE149D, SER143C, SER143D, SER145C, SER145D, SER147C, SER147D, THR142C, THR142D, TRP141C, TRP141D, VAL146C, VAL146D
• C-E: ALA108E, ALA25C, ALA62E, ALA92C, ALA96E, ARG104E, ARG113E, ARG17E, ARG26C, ARG26E, ARG29C, ARG87C, ASN114E, ASN81C, ASN94E, ASP106C, ASP106E, ASP110E, ASP13E, ASP97E, GLN148C, GLN16E, GLN99C, GLN99E, GLU151C, GLU22E, GLU28C, GLY101C, GLY101E, GLY105C, GLY105E, GLY112E, GLY14E, GLY31C, GLY79C, GLY91C, HIS144C, ILE103C, ILE103E, ILE149C, LEU19E, LEU89C, LEU90C, LYS30C, LYS80C, LYS84C, PHE107E, PHE27C, PRO100C, PRO100E, PRO12E, PRO95E, SER145C, SER147C, SER85C, SER98C, SER98E, THR102C, THR102E, TYR150C, TYR32C, TYR66E, VAL109E, VAL111E, VAL115E, VAL146C, VAL15E, VAL82C, VAL88C
• C-F: ALA139C, ALA139F, ALA25C, ALA25F, ALA36C, ALA36F, ARG17C, ARG17F, ARG26C, ARG26F, ARG29C, ARG29F, ASP136C, ASP13C, ASP13F, CYS74C, CYS74F, GLN16C, GLN16F, GLN41C, GLN41F, GLU137C, GLU137F, GLU22C, GLU22F, GLU28C, GLU28F, GLY14C, GLY14F, GLY18C, GLY18F, GLY21C, GLY21F, GLY31C, GLY31F, GLY70C, GLY70F, HIS144C, HIS144F, ILE138C, ILE138F, ILE23C, ILE23F, ILE24C, ILE24F, ILE39C, ILE39F, ILE72C, ILE72F, LEU19C, LEU19F, LEU34C, LEU34F, LEU37C, LEU37F, LEU40C, LEU40F, LYS134C, LYS134F, LYS33C, LYS33F, LYS38C, LYS38F, MET75C, MET75F, PHE133C, PHE133F, PHE27C, PHE27F, PRO12C, PRO12F, PRO71C, PRO71F, SER140C, SER140F, SER143C, SER143F, SER145C, SER145F, SER69C, SER69F, THR142C, THR142F, TRP141C, TRP141F, TRP77C, TRP77F, TYR32C, TYR32F, VAL10C, VAL10F, VAL146C, VAL146F, VAL15C, VAL15F, VAL20C, VAL20F, VAL35C, VAL35F, VAL73C, VAL73F, VAL76C, VAL76F
• D-E: ALA139D, ALA139E, ALA25D, ALA25E, ALA36D, ALA36E, ARG17D, ARG17E, ARG26D, ARG26E, ARG29D, ARG29E, ASP136D, ASP136E, ASP13D, ASP13E, CYS74D, CYS74E, GLN16D, GLN16E, GLN41D, GLN41E, GLU137D, GLU137E, GLU22D, GLU22E, GLU28D, GLU28E, GLY14D, GLY14E, GLY18D, GLY18E, GLY21D, GLY21E, GLY31D, GLY31E, GLY70D, GLY70E, HIS144D, HIS144E, ILE138D, ILE138E, ILE23D, ILE23E, ILE24D, ILE24E, ILE39D, ILE39E, ILE72D, ILE72E, LEU19D, LEU19E, LEU34D, LEU34E, LEU37D, LEU37E, LEU40D, LEU40E, LYS134D, LYS134E, LYS33D, LYS33E, LYS38D, LYS38E, MET75D, MET75E, PHE107D, PHE133D, PHE133E, PHE27D, PHE27E, PRO12D, PRO12E, PRO71D, PRO71E, SER140D, SER140E, SER143D, SER143E, SER145D, SER145E, SER69D, SER69E, THR142D, THR142E, TRP141D, TRP141E, TRP77D, TRP77E, TYR32D, TYR32E, VAL10D, VAL10E, VAL146D, VAL146E, VAL15D, VAL15E, VAL20D, VAL20E, VAL35D, VAL35E, VAL73D, VAL73E, VAL76D, VAL76E
• D-F: ALA108F, ALA25D, ALA62F, ALA92D, ALA96F, ARG104F, ARG113F, ARG17F, ARG26D, ARG26F, ARG29D, ARG87D, ASN114F, ASN81D, ASN94F, ASP106D, ASP106F, ASP110F, ASP13F, ASP97F, GLN148D, GLN16F, GLN99D, GLN99F, GLU151D, GLU22F, GLU28D, GLU78D, GLY101D, GLY101F, GLY105F, GLY112F, GLY14F, GLY31D, GLY79D, GLY91D, HIS144D, ILE103D, ILE103F, ILE149D, LEU19F, LEU63F, LEU89D, LEU90D, LYS30D, LYS80D, LYS84D, PHE107F, PHE27D, PHE59F, PRO100D, PRO100F, PRO12F, PRO95F, SER145D, SER147D, SER2D, SER3D, SER69F, SER85D, SER98F, THR102D, THR102F, TYR150D, TYR32D, TYR66F, VAL109F, VAL111F, VAL115F, VAL146D, VAL15F, VAL82D, VAL88D
• D-N: ALA47D, ALA47N, ALA62D, ALA62N, ASP53D, ASP53N, CYS55D, CYS55N, GLN48D, GLN48N, GLU45D, GLU45N, GLY49D, GLY49N, LEU54D, LEU54N, LEU63D, LYS52D, LYS52N, LYS57D, LYS57N, LYS65D, LYS65N, PHE59D, PHE59N, PHE60D, PHE60N, PRO58D, PRO58N, PRO61D, PRO61N, SER56D, SER56N, SER68D, THR44D, THR44N, TYR51D, TYR51N, VAL64D, VAL64N
• G-H: ALA139G, ALA139H, ALA25G, ALA25H, ALA36G, ALA36H, ARG17G, ARG17H, ARG26G, ARG26H, ARG29G, ARG29H, ASP136G, ASP136H, ASP13G, ASP13H, CYS74G, CYS74H, GLN16G, GLN16H, GLN41G, GLN41H, GLU137G, GLU137H, GLU22G, GLU22H, GLU28G, GLU28H, GLY14G, GLY14H, GLY18G, GLY18H, GLY21G, GLY21H, GLY31G, GLY70G, GLY70H, HIS144G, HIS144H, ILE138G, ILE138H, ILE23G, ILE23H, ILE24G, ILE24H, ILE39G, ILE39H, ILE72G, ILE72H, LEU19G, LEU19H, LEU34G, LEU34H, LEU37G, LEU37H, LEU40G, LEU40H, LYS33G, LYS33H, LYS38G, LYS38H, MET75G, MET75H, PHE133G, PHE133H, PHE27G, PHE27H, PRO12G, PRO12H, PRO71G, PRO71H, SER140G, SER140H, SER143G, SER143H, SER145G, SER145H, SER69G, SER69H, THR142G, THR142H, TRP141G, TRP141H, TRP77G, TRP77H, TYR32G, TYR32H, TYR66H, VAL10G, VAL10H, VAL146G, VAL146H, VAL15G, VAL15H, VAL20G, VAL20H, VAL35G, VAL35H, VAL73G, VAL73H, VAL76G, VAL76H
• G-I: ALA108I, ALA25G, ALA62I, ALA96I, ARG104I, ARG113I, ARG17I, ARG26G, ARG26I, ARG29G, ARG87G, ASN114I, ASN81G, ASN94I, ASP106G, ASP106I, ASP110I, ASP13I, ASP97I, GLN148G, GLN16I, GLN99G, GLN99I, GLU151G, GLU22I, GLU28G, GLU78G, GLY101G, GLY101I, GLY105G, GLY105I, GLY112I, GLY14I, GLY18I, GLY31G, GLY79G, GLY91G, HIS144G, ILE103G, ILE103I, ILE149G, LEU19I, LEU89G, LEU90G, LYS30G, LYS33G, LYS80G, LYS84G, PHE107I, PHE27G, PHE59I, PRO100G, PRO100I, PRO12I, PRO95I, SER145G, SER147G, SER85G, SER98I, THR102G, THR102I, TYR150G, TYR32G, TYR66I, VAL109I, VAL111I, VAL115I, VAL146G, VAL15I, VAL82G, VAL88G
• G-K: ALA108G, ALA25K, ALA62G, ALA92K, ALA96G, ARG104G, ARG113G, ARG17G, ARG26G, ARG26K, ARG29K, ARG87K, ASN114G, ASN81K, ASN94G, ASP106G, ASP106K, ASP110G, ASP13G, ASP97G, GLN148K, GLN16G, GLN99G, GLN99K, GLU151K, GLU22G, GLU28K, GLY101G, GLY101K, GLY105G, GLY105K, GLY112G, GLY14G, GLY18G, GLY31K, GLY79K, GLY86K, GLY91K, HIS144K, ILE103G, ILE103K, ILE149K, LEU19G, LEU63G, LEU89K, LEU90K, LYS11G, LYS30K, LYS80K, LYS84K, PHE107G, PHE27K, PHE59G, PRO100G, PRO100K, PRO12G, PRO95G, SER145K, SER147K, SER85K, SER98G, THR102G, THR102K, TYR150K, TYR32K, TYR66G, VAL109G, VAL111G, VAL115G, VAL146K, VAL15G, VAL82K, VAL88K
• G-L: GLN148G, GLN148L, HIS144G, HIS144L, ILE149G, ILE149L, SER143G, SER143L, SER145G, SER145L, SER147G, SER147L, THR142G, THR142L, TRP141G, TRP141L, VAL146G, VAL146L
• H-J: ALA108J, ALA25H, ALA62J, ALA96J, ARG104J, ARG113J, ARG17J, ARG26H, ARG26J, ARG29H, ARG87H, ASN114J, ASN81H, ASN94J, ASP106H, ASP106J, ASP110J, ASP13J, ASP97J, GLN148H, GLN16J, GLN99H, GLN99J, GLU151H, GLU22J, GLU28H, GLU78H, GLY101H, GLY101J, GLY105H, GLY105J, GLY112J, GLY14J, GLY18J, GLY31H, GLY79H, GLY91H, HIS144H, ILE103H, ILE103J, ILE149H, LEU19J, LEU63J, LEU89H, LEU90H, LYS30H, LYS33H, LYS65J, LYS80H, LYS84H, PHE107J, PHE27H, PHE59J, PRO100H, PRO100J, PRO12J, PRO95J, SER145H, SER147H, SER3H, SER69J, SER85H, SER98J, THR102H, THR102J, TYR150H, TYR32H, TYR66J, VAL109J, VAL111J, VAL115J, VAL146H, VAL15J, VAL82H, VAL88H
• H-K: ARG29H, ARG29K, GLN148H, GLN148K, HIS144H, HIS144K, ILE149H, ILE149K, SER143H, SER143K, SER145H, SER145K, SER147H, SER147K, THR142H, THR142K, TRP141H, TRP141K, VAL146H, VAL146K
• H-L: ALA108H, ALA25L, ALA92L, ALA96H, ARG104H, ARG113H, ARG17H, ARG26H, ARG26L, ARG29L, ARG87L, ASN114H, ASN81L, ASN94H, ASP106H, ASP106L, ASP110H, ASP13H, ASP97H, GLN148L, GLN16H, GLN99H, GLN99L, GLU22H, GLU28L, GLU78L, GLY101H, GLY101L, GLY105H, GLY105L, GLY112H, GLY14H, GLY31L, GLY79L, GLY91L, HIS144L, ILE103H, ILE103L, ILE149L, LEU19H, LEU89L, LEU90L, LYS30L, LYS33L, LYS80L, LYS84L, PHE107H, PHE27L, PRO100H, PRO100L, PRO12H, PRO95H, SER145L, SER147L, SER2L, SER69H, SER85L, SER98H, THR102H, THR102L, TYR150L, TYR32L, TYR66H, VAL109H, VAL111H, VAL115H, VAL146L, VAL15H, VAL82L, VAL88L
• I-J: GLN148I, GLN148J, HIS144I, HIS144J, ILE149I, ILE149J, SER143I, SER143J, SER145I, SER145J, SER147I, SER147J, THR142I, THR142J, TRP141I, TRP141J, VAL146I, VAL146J
• I-K: ALA108K, ALA25I, ALA62K, ALA96K, ARG104K, ARG113K, ARG17K, ARG26I, ARG26K, ARG29I, ARG29K, ARG87I, ASN114K, ASN81I, ASN94K, ASP106I, ASP106K, ASP110K, ASP13K, ASP97K, GLN148I, GLN16K, GLN99I, GLN99K, GLU151I, GLU22K, GLU28I, GLU78I, GLY101I, GLY101K, GLY105I, GLY105K, GLY112K, GLY14K, GLY31I, GLY70K, GLY79I, GLY91I, HIS144I, ILE103I, ILE103K, ILE149I, LEU19K, LEU63K, LEU89I, LEU90I, LYS30I, LYS80I, LYS84I, PHE107K, PHE27I, PHE59K, PRO100I, PRO100K, PRO12K, PRO71K, PRO95K, SER145I, SER147I, SER2I, SER69K, SER85I, SER98K, THR102I, THR102K, TYR150I, TYR32I, TYR66K, VAL109K, VAL111K, VAL115K, VAL146I, VAL15K, VAL82I, VAL88I
• I-L: ALA139I, ALA139L, ALA25I, ALA25L, ALA36I, ALA36L, ARG17I, ARG17L, ARG26I, ARG26L, ARG29I, ARG29L, ASP136I, ASP136L, ASP13I, ASP13L, CYS74I, CYS74L, GLN16I, GLN16L, GLN41I, GLN41L, GLU137I, GLU137L, GLU22I, GLU22L, GLU28I, GLU28L, GLY14I, GLY14L, GLY18I, GLY18L, GLY21I, GLY21L, GLY31I, GLY31L, GLY70I, GLY70L, HIS144I, HIS144L, ILE138I, ILE138L, ILE149I, ILE23I, ILE23L, ILE24I, ILE24L, ILE39I, ILE39L, ILE72I, ILE72L, LEU19I, LEU19L, LEU34I, LEU34L, LEU37I, LEU37L, LEU40I, LEU40L, LYS134I, LYS134L, LYS33I, LYS33L, LYS38I, LYS38L, MET75I, MET75L, PHE133I, PHE133L, PHE27I, PHE27L, PRO12I, PRO12L, PRO42I, PRO71I, PRO71L, SER140I, SER140L, SER143I, SER143L, SER145I, SER145L, SER69I, SER69L, THR142I, THR142L, TRP141I, TRP141L, TRP77I, TRP77L, TYR32I, TYR32L, VAL10I, VAL10L, VAL146I, VAL146L, VAL15I, VAL15L, VAL20I, VAL20L, VAL35I, VAL35L, VAL73I, VAL73L, VAL76I, VAL76L
• J-K: ALA139J, ALA139K, ALA25J, ALA25K, ALA36J, ALA36K, ARG17J, ARG17K, ARG26J, ARG26K, ARG29J, ARG29K, ASP136J, ASP136K, ASP13J, ASP13K, CYS74J, CYS74K, GLN16J, GLN16K, GLN41J, GLN41K, GLU137J, GLU137K, GLU22J, GLU22K, GLU28J, GLU28K, GLY14J, GLY14K, GLY18J, GLY18K, GLY21J, GLY21K, GLY31K, GLY70J, GLY70K, HIS144J, HIS144K, ILE138J, ILE138K, ILE149J, ILE23J, ILE23K, ILE24J, ILE24K, ILE39J, ILE39K, ILE72J, ILE72K, LEU19J, LEU19K, LEU34J, LEU34K, LEU37J, LEU37K, LEU40J, LEU40K, LYS134J, LYS134K, LYS33J, LYS33K, LYS38J, LYS38K, MET75J, MET75K, PHE133J, PHE133K, PHE27J, PRO12J, PRO12K, PRO71J, PRO71K, SER140J, SER140K, SER143J, SER143K, SER145J, SER145K, SER69J, SER69K, THR142J, THR142K, TRP141J, TRP141K, TRP77J, TRP77K, TYR32J, TYR32K, TYR66J, VAL10J, VAL10K, VAL146J, VAL146K, VAL15J, VAL15K, VAL20J, VAL20K, VAL35J, VAL35K, VAL73J, VAL73K, VAL76J, VAL76K
• J-L: ALA108L, ALA25J, ALA92J, ALA96L, ARG104L, ARG113L, ARG17L, ARG26J, ARG26L, ARG29J, ARG87J, ASN114L, ASN81J, ASN94L, ASP106J, ASP106L, ASP110L, ASP13L, ASP97L, GLN148J, GLN16L, GLN99J, GLN99L, GLU22L, GLU28J, GLU78J, GLY101J, GLY101L, GLY105L, GLY112L, GLY14L, GLY31J, GLY70L, GLY79J, GLY86J, GLY91J, HIS144J, ILE103J, ILE103L, ILE149J, LEU19L, LEU89J, LEU90J, LYS30J, LYS33J, LYS80J, LYS84J, PHE107L, PHE27J, PRO100J, PRO100L, PRO12L, PRO95L, SER145J, SER147J, SER69L, SER85J, SER98J, SER98L, THR102J, THR102L, TYR150J, TYR32J, VAL109L, VAL111L, VAL115L, VAL146J, VAL15L, VAL82J, VAL88J
• M-N: ALA139M, ALA139N, ALA25M, ALA25N, ALA36M, ALA36N, ARG17M, ARG17N, ARG26M, ARG26N, ARG29M, ARG29N, ASP136M, ASP136N, ASP13M, ASP13N, CYS74M, CYS74N, GLN16M, GLN16N, GLN41M, GLN41N, GLU137M, GLU137N, GLU22M, GLU22N, GLU28M, GLU28N, GLY14M, GLY14N, GLY18M, GLY18N, GLY21M, GLY21N, GLY31M, GLY31N, GLY70M, GLY70N, HIS144M, HIS144N, ILE138M, ILE138N, ILE23M, ILE23N, ILE24M, ILE24N, ILE39M, ILE39N, ILE72M, ILE72N, LEU19M, LEU19N, LEU34M, LEU34N, LEU37M, LEU37N, LEU40M, LEU40N, LYS134M, LYS134N, LYS33M, LYS33N, LYS38M, LYS38N, MET75M, MET75N, PHE107N, PHE133M, PHE133N, PHE27M, PHE27N, PRO12M, PRO12N, PRO71M, PRO71N, SER140M, SER140N, SER143M, SER143N, SER145M, SER145N, SER69M, SER69N, THR142M, THR142N, TRP141M, TRP141N, TRP77M, TRP77N, TYR32M, TYR32N, VAL10M, VAL10N, VAL146M, VAL146N, VAL15M, VAL15N, VAL20M, VAL20N, VAL35M, VAL35N, VAL73M, VAL73N, VAL76M, VAL76N