3NG9

structure to function correlations for adeno-associated virus serotype 1

• Total interactions analyzed: 45
• Total true interactions: 22
• Strongest Interaction:
  • Chains: D-H
  • Int. Res.: 340
  • Norm. En. per Res.: -6.0488
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-80.0424	-9.3725	-611.825	-701.2399	207	27	12	25110	1	19	17
A-C	0.0	0.0	-6.7259	-6.7259	11	0	2	457	0	0	1
A-D	-359.9897	-13.1602	-1663.35	-2036.4998	340	122	27	60282	9	64	69
A-E	-64.6657	-159.8301	-316.755	-541.2508	130	18	2	13630	12	32	29
A-H	-354.9491	-13.3376	-1668.77	-2037.0567	341	117	28	60347	9	64	69
A-I	-91.5793	-3.9129	-616.09	-711.5822	206	26	12	25162	0	19	17
B-D	0.0	0.0	-6.6991	-6.6991	10	0	2	449	0	0	1
B-E	-335.8571	-11.0756	-1663.17	-2010.1027	341	121	27	60307	9	64	69
B-G	-358.7015	-13.1527	-1675.96	-2047.8142	340	119	27	60326	9	64	69
B-I	0.0	0.0	-0.0137	-0.0137	7	0	0	16	0	0	1
B-J	-61.2345	-157.464	-316.682	-535.3805	131	17	2	13678	12	32	29
C-F	-370.3128	-13.4615	-1673.45	-2057.2243	341	117	27	60255	9	64	69
C-I	-347.9416	-13.2225	-1664.53	-2025.6941	340	121	27	60300	9	64	69
D-F	-89.7768	-6.2919	-627.839	-723.9077	206	26	12	25277	1	19	17
D-H	-366.9894	-13.2309	-1676.37	-2056.5902	340	113	28	60426	9	64	69
D-I	-64.4171	-159.4935	-316.954	-540.8646	130	19	2	13610	12	32	29
E-G	-346.6923	-12.7034	-1677.5	-2036.8958	340	115	27	60457	9	64	69
E-H	-89.4351	-4.3863	-611.148	-704.9695	206	25	12	25085	0	19	17
F-H	0.0	0.0	-6.7687	-6.7687	11	0	2	461	0	0	1
F-I	-363.5757	-13.2105	-1675.83	-2052.6162	340	113	27	60383	9	64	69
G-H	0.0	0.0	-6.7117	-6.7117	11	0	2	457	0	0	1
G-J	-79.2945	-7.7835	-620.654	-707.7319	208	26	12	25054	1	19	17

Interface residues

• A-B: ALA218B, ALA224A, ALA248A, ALA263B, ALA334A, ALA334B, ALA368A, ALA387B, ALA656B, ALA660B, ALA664B, ALA668B, ALA706A, ALA709A, ARG245A, ARG287A, ARG295A, ARG299A, ARG390B, ARG405A, ARG405B, ASN223A, ASN223B, ASN227A, ASN253A, ASN253B, ASN254A, ASN318A, ASN327A, ASN327B, ASN335A, ASN335B, ASN336A, ASN336B, ASN382B, ASN383B, ASN408A, ASN408B, ASN409B, ASN651A, ASN657B, ASN704A, ASN710A, ASN717A, ASN718A, ASP219A, ASP219B, ASP231A, ASP296A, ASP328A, ASP328B, ASP369A, ASP712A, ASP716A, CYS230A, CYS362A, CYS395B, GLN259B, GLN320A, GLN342B, GLN350B, GLN360A, GLN375A, GLN386B, GLN402B, GLN673A, GLN673B, GLN678A, GLU323A, GLU323B, GLU397B, GLU546A, GLU661B, GLY217B, GLY220A, GLY220B, GLY222A, GLY222B, GLY226A, GLY275B, GLY329A, GLY361A, GLY384B, GLY389B, GLY407A, GLY407B, GLY677A, GLY719A, HIS229A, HIS255B, HIS291A, HIS359A, ILE240A, ILE260B, ILE319A, ILE319B, ILE333A, ILE373A, ILE671B, LEU249A, LEU256B, LEU337A, LEU337B, LEU381B, LEU396B, LEU404B, LEU720A, LYS258B, LYS322A, LYS650B, LYS666B, LYS707A, MET372A, MET403B, PHE274B, PHE292A, PHE317A, PHE344B, PHE366A, PHE371A, PHE393B, PHE399B, PHE662B, PHE667B, PHE670B, PHE713A, PRO250A, PRO279B, PRO294A, PRO364A, PRO365A, PRO367A, PRO374A, PRO400B, PRO653B, PRO655B, PRO658B, PRO659B, SER225A, SER232A, SER243A, SER261B, SER277B, SER293A, SER339B, SER385B, SER391B, SER392B, SER401B, SER663B, SER669B, SER675A, SER703A, SER708A, THR233A, THR241A, THR242A, THR244A, THR246A, THR251A, THR278B, THR325A, THR325B, THR326A, THR326B, THR331A, THR332A, THR332B, THR338B, THR340B, THR380B, THR406A, THR406B, THR652B, THR665B, THR672A, THR672B, THR676A, THR714A, THR722A, TRP228A, TRP234A, TRP247A, TRP280B, TYR252A, TYR257B, TYR276B, TYR282A, TYR378B, TYR394B, TYR398B, TYR674A, TYR705A, TYR721A, VAL221A, VAL221B, VAL321A, VAL324A, VAL330A, VAL330B, VAL341B, VAL343B, VAL370A, VAL388B, VAL654B, VAL711A, VAL715A
• A-C: ALA664A, ARG465C, ASP440C, GLN441C, GLU661A, ILE439C, LEU438C, PHE662A, SER663A, THR665A, TYR442C
• A-D: ALA267A, ALA358A, ALA426D, ALA456D, ALA469D, ALA506A, ALA523A, ALA523D, ALA525D, ALA548A, ALA550A, ALA554A, ALA568D, ALA573A, ALA581D, ALA592D, ALA598A, ALA598D, ALA601A, ALA601D, ALA620A, ARG287A, ARG390A, ARG433D, ARG448D, ARG465D, ARG485A, ARG485D, ARG488A, ARG514A, ARG576A, ARG576D, ARG610A, ARG610D, ARG694D, ARG730D, ARG734D, ASN253A, ASN269A, ASN271A, ASN286A, ASN382A, ASN383A, ASN436D, ASN447D, ASN451D, ASN458D, ASN477D, ASN496A, ASN497A, ASN498A, ASN500A, ASN510A, ASN510D, ASN512A, ASN519A, ASN552A, ASN557A, ASN570A, ASN570D, ASN583D, ASN691D, ASN696D, ASP270A, ASP284A, ASP346A, ASP432D, ASP440D, ASP460D, ASP495A, ASP529D, ASP530D, ASP556A, ASP562D, ASP590D, ASP595A, ASP595D, ASP609A, ASP609D, ASP611D, ASP626A, CYS362A, CYS395A, CYS483A, GLN350A, GLN360A, GLN375A, GLN386A, GLN429D, GLN441D, GLN450D, GLN452D, GLN457D, GLN474D, GLN486A, GLN487A, GLN585D, GLN608A, GLN608D, GLN615A, GLN646A, GLN688D, GLU348A, GLU397A, GLU515A, GLU531A, GLU531D, GLU546A, GLU563D, GLU564D, GLU565D, GLU575A, GLU575D, GLU698D, GLY275A, GLY281A, GLY306D, GLY356A, GLY361A, GLY377A, GLY384A, GLY389A, GLY466D, GLY470D, GLY481A, GLY481D, GLY505A, GLY513A, GLY513D, GLY521A, GLY539A, GLY544A, GLY549A, GLY578D, GLY594D, GLY600A, GLY600D, GLY604D, GLY616A, GLY627A, GLY627D, GLY636A, GLY637A, GLY639A, HIS272A, HIS289A, HIS359A, HIS422D, HIS427D, HIS527D, HIS597A, HIS597D, HIS624A, HIS628A, HIS628D, HIS630A, HIS630D, ILE260A, ILE373A, ILE439D, ILE517A, ILE518A, ILE542A, ILE560A, ILE566D, ILE618A, ILE622A, LEU351A, LEU355A, LEU379A, LEU381A, LEU396A, LEU431D, LEU434D, LEU438D, LEU443D, LEU446D, LEU461D, LEU462D, LEU479D, LEU511A, LEU555A, LEU602A, LEU602D, LEU634A, LEU640A, LEU648A, LEU732D, LEU736D, LYS258A, LYS459D, LYS476D, LYS491A, LYS493A, LYS508A, LYS528A, LYS528D, LYS533A, LYS545A, LYS567D, LYS621A, LYS641A, LYS693D, MET435D, MET471D, MET524A, MET537A, MET541A, MET559A, MET599A, MET599D, MET605A, MET605D, MET635A, PHE274A, PHE288A, PHE344A, PHE393A, PHE399A, PHE421D, PHE463D, PHE501A, PHE534A, PHE535A, PHE543A, PHE577A, PHE577D, PHE584A, PHE584D, PHE629A, PHE629D, PHE638A, PRO279A, PRO352A, PRO374A, PRO400A, PRO420D, PRO437D, PRO468D, PRO475D, PRO480D, PRO482A, PRO482D, PRO520A, PRO536A, PRO571D, PRO591D, PRO603A, PRO603D, PRO617A, PRO623A, PRO631A, PRO633A, PRO697D, PRO735D, SER261A, SER262A, SER268A, SER277A, SER357A, SER391A, SER392A, SER423D, SER424D, SER428D, SER430D, SER464D, SER467D, SER472D, SER490A, SER499A, SER507A, SER516A, SER538A, SER547A, SER551A, SER586D, SER587D, SER588D, SER632A, SER632D, SER692D, THR265A, THR278A, THR380A, THR449D, THR492A, THR494A, THR502A, THR504A, THR522A, THR553A, THR561A, THR569D, THR574A, THR579D, THR589D, THR593D, THR625A, THR733D, TRP280A, TRP305D, TRP478D, TRP503A, TRP607A, TRP607D, TRP619A, TRP695D, TYR252A, TYR273A, TYR276A, TYR282A, TYR349A, TYR353A, TYR376A, TYR378A, TYR394A, TYR398A, TYR425D, TYR442D, TYR444D, TYR445D, TYR484A, TYR509A, TYR613A, TYR731D, VAL354A, VAL388A, VAL473D, VAL489A, VAL540A, VAL558A, VAL572A, VAL572D, VAL580D, VAL582D, VAL596A, VAL596D, VAL606D, VAL699D
• A-E: ALA368A, ALA368E, ALA706A, ALA706E, ARG245A, ARG245E, ARG295A, ARG295E, ARG299A, ARG299E, ARG694A, ARG694E, ARG725A, ARG725E, ASN302A, ASN302E, ASN303A, ASN303E, ASN304A, ASN304E, ASN691A, ASN691E, ASN696A, ASN696E, ASN704A, ASN704E, ASP231A, ASP231E, ASP296A, ASP296E, ASP529A, ASP529E, ASP530A, ASP530E, ASP532A, ASP532E, ASP712A, ASP712E, CYS230A, CYS230E, GLN298A, GLN298E, GLN700A, GLN700E, GLU564A, GLU564E, GLU690A, GLU690E, GLU698A, GLU698E, GLU723A, GLU723E, GLY236A, GLY236E, HIS289A, HIS289E, HIS291A, HIS291E, ILE301A, ILE301E, ILE727A, ILE727E, LEU614A, LEU614E, LEU732A, LEU732E, LYS689A, LYS689E, LYS693A, LYS693E, LYS707A, LYS707E, PHE292A, PHE292E, PHE366A, PHE366E, PHE713A, PHE713E, PRO294A, PRO294E, PRO364A, PRO364E, PRO365A, PRO365E, PRO367A, PRO367E, PRO697A, PRO697E, PRO724A, PRO724E, SER232A, SER232E, SER243A, SER243E, SER293A, SER293E, SER692A, SER692E, SER703A, SER703E, THR233A, THR233E, THR702A, THR702E, THR714A, THR714E, THR733A, THR733E, TRP234A, TRP234E, TRP297A, TRP297E, TRP305A, TRP305E, TRP695A, TRP695E, TYR701A, TYR701E, TYR705A, TYR705E, TYR721A, TYR721E, TYR731A, TYR731E, VAL699A, VAL699E, VAL711A, VAL711E, VAL715A, VAL715E
• A-H: ALA267H, ALA358H, ALA426A, ALA456A, ALA469A, ALA506H, ALA523A, ALA523H, ALA525A, ALA548H, ALA550H, ALA554H, ALA568A, ALA573H, ALA581A, ALA592A, ALA598A, ALA598H, ALA601A, ALA601H, ALA620H, ARG287H, ARG390H, ARG433A, ARG448A, ARG465A, ARG485A, ARG485H, ARG488H, ARG514H, ARG576A, ARG576H, ARG610A, ARG610H, ARG694A, ARG730A, ARG734A, ASN253H, ASN269H, ASN271H, ASN286H, ASN382H, ASN383H, ASN436A, ASN447A, ASN451A, ASN458A, ASN477A, ASN496H, ASN497H, ASN498H, ASN500H, ASN510A, ASN510H, ASN512H, ASN519H, ASN552H, ASN557H, ASN570A, ASN570H, ASN583A, ASN691A, ASN696A, ASP270H, ASP284H, ASP346H, ASP432A, ASP440A, ASP460A, ASP495H, ASP529A, ASP530A, ASP556H, ASP562A, ASP590A, ASP595A, ASP595H, ASP609A, ASP609H, ASP611A, ASP626H, CYS362H, CYS395H, CYS483A, CYS483H, GLN350H, GLN360H, GLN375H, GLN386H, GLN429A, GLN441A, GLN450A, GLN452A, GLN457A, GLN474A, GLN486H, GLN487H, GLN585A, GLN608A, GLN608H, GLN615H, GLN646H, GLN688A, GLU348H, GLU397H, GLU515H, GLU531A, GLU531H, GLU546H, GLU563A, GLU564A, GLU565A, GLU575A, GLU575H, GLU698A, GLY275H, GLY281H, GLY306A, GLY356H, GLY361H, GLY377H, GLY384H, GLY389H, GLY466A, GLY470A, GLY481A, GLY481H, GLY505H, GLY513A, GLY513H, GLY521H, GLY539H, GLY544H, GLY549H, GLY578A, GLY594A, GLY600A, GLY600H, GLY604A, GLY616H, GLY627A, GLY627H, GLY636H, GLY637H, GLY639H, HIS272H, HIS289H, HIS359H, HIS422A, HIS427A, HIS527A, HIS597A, HIS597H, HIS624H, HIS628A, HIS628H, HIS630A, HIS630H, ILE260H, ILE373H, ILE439A, ILE517H, ILE518H, ILE542H, ILE560H, ILE566A, ILE618H, ILE622H, LEU351H, LEU355H, LEU379H, LEU381H, LEU396H, LEU431A, LEU434A, LEU438A, LEU443A, LEU446A, LEU461A, LEU462A, LEU479A, LEU511H, LEU555H, LEU602A, LEU602H, LEU634H, LEU640H, LEU648H, LEU732A, LEU736A, LYS258H, LYS459A, LYS476A, LYS491H, LYS493H, LYS508H, LYS528A, LYS528H, LYS533H, LYS545H, LYS567A, LYS621H, LYS641H, LYS693A, MET435A, MET471A, MET524H, MET537H, MET541H, MET559H, MET599A, MET599H, MET605A, MET605H, MET635H, PHE274H, PHE288H, PHE344H, PHE393H, PHE399H, PHE421A, PHE463A, PHE501H, PHE534H, PHE535H, PHE543H, PHE577A, PHE577H, PHE584A, PHE584H, PHE629A, PHE629H, PHE638H, PRO279H, PRO352H, PRO374H, PRO400H, PRO420A, PRO437A, PRO468A, PRO475A, PRO480A, PRO482A, PRO482H, PRO520H, PRO536H, PRO571A, PRO591A, PRO603A, PRO603H, PRO617H, PRO623H, PRO631H, PRO633H, PRO697A, PRO735A, SER261H, SER262H, SER268H, SER277H, SER357H, SER391H, SER392H, SER423A, SER424A, SER428A, SER430A, SER464A, SER467A, SER472A, SER490H, SER499H, SER507H, SER516H, SER538H, SER547H, SER551H, SER586A, SER587A, SER588A, SER632A, SER632H, SER692A, THR265H, THR278H, THR380H, THR449A, THR492H, THR494H, THR502H, THR504H, THR522H, THR553H, THR561H, THR569A, THR574H, THR579A, THR589A, THR593A, THR625H, THR733A, TRP280H, TRP305A, TRP478A, TRP503H, TRP607A, TRP607H, TRP619H, TRP695A, TYR252H, TYR273H, TYR276H, TYR282H, TYR349H, TYR353H, TYR376H, TYR378H, TYR394H, TYR398H, TYR425A, TYR442A, TYR444A, TYR445A, TYR484H, TYR509H, TYR613H, TYR731A, VAL354H, VAL388H, VAL473A, VAL489H, VAL540H, VAL558H, VAL572A, VAL572H, VAL580A, VAL582A, VAL596A, VAL596H, VAL606A, VAL699A
• A-I: ALA218A, ALA218I, ALA224I, ALA248I, ALA263A, ALA334A, ALA334I, ALA368I, ALA387A, ALA656A, ALA660A, ALA664A, ALA668A, ALA706I, ALA709I, ARG245I, ARG287I, ARG295I, ARG299I, ARG390A, ARG405A, ARG405I, ASN223A, ASN223I, ASN227I, ASN253A, ASN253I, ASN254I, ASN318I, ASN327A, ASN327I, ASN335A, ASN335I, ASN336A, ASN336I, ASN382A, ASN383A, ASN408A, ASN408I, ASN409A, ASN651I, ASN657A, ASN704I, ASN710I, ASN717I, ASN718I, ASP219A, ASP219I, ASP231I, ASP296I, ASP328A, ASP328I, ASP369I, ASP712I, ASP716I, CYS230I, CYS362I, CYS395A, GLN259A, GLN320I, GLN342A, GLN350A, GLN360I, GLN375I, GLN386A, GLN402A, GLN673A, GLN673I, GLN678I, GLU323A, GLU323I, GLU397A, GLU546I, GLU661A, GLY217A, GLY220A, GLY220I, GLY222A, GLY222I, GLY226I, GLY275A, GLY329I, GLY361I, GLY384A, GLY389A, GLY407A, GLY407I, GLY677I, GLY719I, HIS229I, HIS255A, HIS291I, HIS359I, ILE260A, ILE319A, ILE319I, ILE333I, ILE373I, ILE671A, LEU249I, LEU256A, LEU337A, LEU337I, LEU381A, LEU396A, LEU404A, LEU720I, LYS258A, LYS322I, LYS650A, LYS666A, LYS707I, MET372I, MET403A, PHE274A, PHE292I, PHE317I, PHE344A, PHE366I, PHE371I, PHE393A, PHE399A, PHE662A, PHE667A, PHE670A, PHE713I, PRO250I, PRO279A, PRO294I, PRO364I, PRO365I, PRO367I, PRO374I, PRO400A, PRO653A, PRO655A, PRO658A, PRO659A, SER225I, SER232I, SER243I, SER261A, SER277A, SER293I, SER339A, SER385A, SER391A, SER392A, SER401A, SER663A, SER669A, SER675I, SER703I, SER708I, THR233I, THR241I, THR242I, THR244I, THR246I, THR251I, THR278A, THR325A, THR325I, THR326A, THR326I, THR331I, THR332I, THR338A, THR340A, THR380A, THR406A, THR406I, THR652A, THR665A, THR672A, THR672I, THR676I, THR714I, THR722I, TRP228I, TRP234I, TRP247I, TRP280A, TRP297I, TYR252I, TYR257A, TYR276A, TYR282I, TYR378A, TYR394A, TYR398A, TYR674I, TYR705I, TYR721I, VAL221A, VAL221I, VAL321I, VAL324I, VAL330I, VAL341A, VAL343A, VAL370I, VAL388A, VAL654A, VAL711I, VAL715I
• B-D: ALA664B, ARG465D, ASP440D, GLU661B, ILE439D, LEU438D, PHE662B, SER663B, THR665B, TYR442D
• B-E: ALA267B, ALA358B, ALA426E, ALA456E, ALA469E, ALA506B, ALA523B, ALA523E, ALA525E, ALA548B, ALA550B, ALA554B, ALA568E, ALA573B, ALA581E, ALA592E, ALA598B, ALA598E, ALA601B, ALA601E, ALA620B, ARG287B, ARG390B, ARG433E, ARG448E, ARG465E, ARG485B, ARG485E, ARG488B, ARG514B, ARG576B, ARG576E, ARG610B, ARG610E, ARG694E, ARG730E, ARG734E, ASN253B, ASN269B, ASN271B, ASN286B, ASN382B, ASN383B, ASN436E, ASN447E, ASN451E, ASN458E, ASN477E, ASN496B, ASN497B, ASN498B, ASN500B, ASN510B, ASN510E, ASN512B, ASN519B, ASN552B, ASN557B, ASN570B, ASN570E, ASN583E, ASN691E, ASN696E, ASP270B, ASP284B, ASP346B, ASP432E, ASP440E, ASP460E, ASP495B, ASP529E, ASP530E, ASP556B, ASP562E, ASP590E, ASP595B, ASP595E, ASP609B, ASP609E, ASP611E, ASP626B, CYS290B, CYS362B, CYS395B, CYS483B, GLN350B, GLN360B, GLN375B, GLN386B, GLN429E, GLN441E, GLN450E, GLN452E, GLN457E, GLN474E, GLN486B, GLN487B, GLN585E, GLN608B, GLN608E, GLN615B, GLN646B, GLN688E, GLU348B, GLU397B, GLU515B, GLU531B, GLU531E, GLU546B, GLU563E, GLU564E, GLU565E, GLU575B, GLU575E, GLU698E, GLY275B, GLY281B, GLY306E, GLY356B, GLY361B, GLY377B, GLY384B, GLY389B, GLY466E, GLY470E, GLY481B, GLY481E, GLY505B, GLY513B, GLY513E, GLY521B, GLY539B, GLY544B, GLY549B, GLY578E, GLY594E, GLY600B, GLY600E, GLY604E, GLY616B, GLY627B, GLY627E, GLY636B, GLY637B, GLY639B, HIS272B, HIS289B, HIS359B, HIS422E, HIS427E, HIS527E, HIS597B, HIS597E, HIS624B, HIS628B, HIS628E, HIS630B, HIS630E, ILE260B, ILE373B, ILE439E, ILE517B, ILE518B, ILE542B, ILE560B, ILE566E, ILE618B, ILE622B, LEU351B, LEU355B, LEU379B, LEU381B, LEU396B, LEU431E, LEU434E, LEU438E, LEU443E, LEU446E, LEU461E, LEU462E, LEU479E, LEU511B, LEU555B, LEU602B, LEU602E, LEU634B, LEU640B, LEU648B, LEU732E, LEU736E, LYS258B, LYS459E, LYS476E, LYS491B, LYS493B, LYS508B, LYS528B, LYS528E, LYS533B, LYS545B, LYS567E, LYS621B, LYS641B, LYS693E, MET435E, MET471E, MET524B, MET537B, MET541B, MET559B, MET599B, MET599E, MET605B, MET605E, MET635B, PHE274B, PHE288B, PHE344B, PHE393B, PHE399B, PHE421E, PHE463E, PHE501B, PHE534B, PHE535B, PHE543B, PHE577B, PHE577E, PHE584B, PHE584E, PHE629B, PHE629E, PHE638B, PRO279B, PRO352B, PRO374B, PRO400B, PRO420E, PRO437E, PRO468E, PRO475E, PRO480E, PRO482B, PRO482E, PRO520B, PRO536B, PRO571E, PRO591E, PRO603B, PRO603E, PRO617B, PRO623B, PRO631B, PRO633B, PRO697E, PRO735E, SER261B, SER262B, SER268B, SER277B, SER357B, SER391B, SER392B, SER423E, SER424E, SER428E, SER430E, SER464E, SER467E, SER472E, SER490B, SER499B, SER507B, SER516B, SER538B, SER547B, SER551B, SER586E, SER587E, SER588E, SER632B, SER632E, SER692E, THR265B, THR278B, THR380B, THR449E, THR492B, THR494B, THR502B, THR504B, THR522B, THR553B, THR561B, THR569E, THR574B, THR579E, THR589E, THR593E, THR625B, THR733E, TRP280B, TRP305E, TRP478E, TRP503B, TRP607B, TRP607E, TRP619B, TRP695E, TYR252B, TYR273B, TYR276B, TYR282B, TYR349B, TYR353B, TYR376B, TYR378B, TYR394B, TYR398B, TYR425E, TYR442E, TYR444E, TYR445E, TYR484B, TYR509B, TYR613B, TYR731E, VAL354B, VAL388B, VAL473E, VAL489B, VAL540B, VAL558B, VAL572B, VAL572E, VAL580E, VAL582E, VAL596B, VAL596E, VAL606E, VAL699E
• B-G: ALA267G, ALA358G, ALA426B, ALA456B, ALA469B, ALA506G, ALA523B, ALA523G, ALA525B, ALA548G, ALA550G, ALA554G, ALA568B, ALA573G, ALA581B, ALA592B, ALA598B, ALA598G, ALA601B, ALA601G, ALA620G, ARG287G, ARG390G, ARG433B, ARG448B, ARG465B, ARG485B, ARG485G, ARG488G, ARG514G, ARG576B, ARG576G, ARG610B, ARG610G, ARG694B, ARG730B, ARG734B, ASN253G, ASN269G, ASN271G, ASN286G, ASN382G, ASN383G, ASN436B, ASN447B, ASN451B, ASN458B, ASN477B, ASN496G, ASN497G, ASN498G, ASN500G, ASN510B, ASN510G, ASN512G, ASN519G, ASN552G, ASN557G, ASN570B, ASN570G, ASN583B, ASN691B, ASN696B, ASP270G, ASP284G, ASP346G, ASP432B, ASP440B, ASP460B, ASP495G, ASP529B, ASP530B, ASP556G, ASP562B, ASP590B, ASP595B, ASP595G, ASP609B, ASP609G, ASP611B, ASP626G, CYS362G, CYS395G, CYS483G, GLN350G, GLN360G, GLN375G, GLN386G, GLN429B, GLN441B, GLN450B, GLN452B, GLN457B, GLN474B, GLN486G, GLN487G, GLN585B, GLN608B, GLN608G, GLN615G, GLN646G, GLN688B, GLU348G, GLU397G, GLU515G, GLU531B, GLU531G, GLU546G, GLU563B, GLU564B, GLU565B, GLU575B, GLU575G, GLU698B, GLY275G, GLY281G, GLY306B, GLY356G, GLY361G, GLY377G, GLY384G, GLY389G, GLY466B, GLY470B, GLY481B, GLY481G, GLY505G, GLY513B, GLY513G, GLY521G, GLY539G, GLY544G, GLY549G, GLY578B, GLY594B, GLY600B, GLY600G, GLY604B, GLY616G, GLY627B, GLY627G, GLY636G, GLY637G, GLY639G, HIS272G, HIS289G, HIS359G, HIS422B, HIS427B, HIS527B, HIS597B, HIS597G, HIS624G, HIS628B, HIS628G, HIS630B, HIS630G, ILE260G, ILE373G, ILE439B, ILE517G, ILE518G, ILE542G, ILE560G, ILE566B, ILE618G, ILE622G, LEU351G, LEU355G, LEU379G, LEU381G, LEU396G, LEU431B, LEU434B, LEU438B, LEU443B, LEU446B, LEU461B, LEU462B, LEU479B, LEU511G, LEU555G, LEU602B, LEU602G, LEU634G, LEU640G, LEU648G, LEU732B, LEU736B, LYS258G, LYS459B, LYS476B, LYS491G, LYS493G, LYS508G, LYS528B, LYS528G, LYS533G, LYS545G, LYS567B, LYS621G, LYS641G, LYS693B, MET435B, MET471B, MET524G, MET537G, MET541G, MET559G, MET599B, MET599G, MET605B, MET605G, MET635G, PHE274G, PHE288G, PHE344G, PHE393G, PHE399G, PHE421B, PHE463B, PHE501G, PHE534G, PHE535G, PHE543G, PHE577B, PHE577G, PHE584B, PHE584G, PHE629B, PHE629G, PHE638G, PRO279G, PRO352G, PRO374G, PRO400G, PRO420B, PRO437B, PRO468B, PRO475B, PRO480B, PRO482B, PRO482G, PRO520G, PRO536G, PRO571B, PRO591B, PRO603B, PRO603G, PRO617G, PRO623G, PRO631G, PRO633G, PRO697B, PRO735B, SER261G, SER262G, SER268G, SER277G, SER357G, SER391G, SER392G, SER423B, SER424B, SER428B, SER430B, SER464B, SER467B, SER472B, SER490G, SER499G, SER507G, SER516G, SER538G, SER547G, SER551G, SER586B, SER587B, SER588B, SER632B, SER632G, SER692B, THR265G, THR278G, THR380G, THR449B, THR492G, THR494G, THR502G, THR504G, THR522G, THR553G, THR561G, THR569B, THR574G, THR579B, THR589B, THR593B, THR625G, THR733B, TRP280G, TRP305B, TRP478B, TRP503G, TRP607B, TRP607G, TRP619G, TRP695B, TYR252G, TYR273G, TYR276G, TYR282G, TYR349G, TYR353G, TYR376G, TYR378G, TYR394G, TYR398G, TYR425B, TYR442B, TYR444B, TYR445B, TYR484G, TYR509G, TYR613G, TYR731B, VAL354G, VAL388G, VAL473B, VAL489G, VAL540G, VAL558G, VAL572B, VAL572G, VAL580B, VAL582B, VAL596B, VAL596G, VAL606B, VAL699B
• B-I: ARG405B, GLY222I, LEU337B, LEU337I, THR338B, VAL221B, VAL221I
• B-J: ALA368B, ALA368J, ALA706B, ALA706J, ARG245B, ARG245J, ARG295B, ARG295J, ARG299B, ARG299J, ARG694B, ARG694J, ARG725B, ARG725J, ASN302B, ASN302J, ASN303B, ASN303J, ASN304B, ASN304J, ASN691B, ASN691J, ASN696B, ASN696J, ASN704B, ASN704J, ASP231B, ASP231J, ASP296B, ASP296J, ASP529B, ASP529J, ASP530B, ASP530J, ASP532B, ASP532J, ASP712B, ASP712J, CYS230B, CYS230J, CYS290B, GLN298B, GLN298J, GLN700B, GLN700J, GLU564B, GLU564J, GLU690B, GLU690J, GLU698B, GLU698J, GLU723B, GLU723J, GLY236B, GLY236J, HIS289B, HIS289J, HIS291B, HIS291J, ILE301B, ILE301J, ILE727B, ILE727J, LEU614B, LEU614J, LEU732B, LEU732J, LYS689B, LYS689J, LYS693B, LYS693J, LYS707B, LYS707J, PHE292B, PHE292J, PHE366B, PHE366J, PHE713B, PHE713J, PRO294B, PRO294J, PRO364B, PRO364J, PRO365B, PRO365J, PRO367B, PRO367J, PRO697B, PRO697J, PRO724B, PRO724J, SER232B, SER232J, SER243B, SER243J, SER293B, SER293J, SER692B, SER692J, SER703B, SER703J, THR233B, THR233J, THR702B, THR702J, THR714B, THR714J, THR733B, THR733J, TRP234B, TRP234J, TRP297B, TRP297J, TRP305B, TRP305J, TRP695B, TRP695J, TYR701B, TYR701J, TYR705B, TYR705J, TYR721B, TYR721J, TYR731B, TYR731J, VAL699B, VAL699J, VAL711B, VAL711J, VAL715B, VAL715J
• C-F: ALA267C, ALA358C, ALA426F, ALA456F, ALA469F, ALA506C, ALA523C, ALA523F, ALA525F, ALA548C, ALA550C, ALA554C, ALA568F, ALA573C, ALA581F, ALA592F, ALA598C, ALA598F, ALA601C, ALA601F, ALA620C, ARG287C, ARG390C, ARG433F, ARG448F, ARG465F, ARG485C, ARG485F, ARG488C, ARG514C, ARG576C, ARG576F, ARG610C, ARG610F, ARG694F, ARG730F, ARG734F, ASN253C, ASN269C, ASN271C, ASN286C, ASN382C, ASN383C, ASN436F, ASN447F, ASN451F, ASN458F, ASN477F, ASN496C, ASN497C, ASN498C, ASN500C, ASN510C, ASN510F, ASN512C, ASN519C, ASN552C, ASN557C, ASN570C, ASN570F, ASN583F, ASN691F, ASN696F, ASP270C, ASP284C, ASP346C, ASP432F, ASP440F, ASP460F, ASP495C, ASP529F, ASP530F, ASP556C, ASP562F, ASP590F, ASP595C, ASP595F, ASP609C, ASP609F, ASP611F, ASP626C, CYS290C, CYS362C, CYS395C, CYS483C, GLN350C, GLN360C, GLN375C, GLN386C, GLN429F, GLN441F, GLN450F, GLN452F, GLN457F, GLN474F, GLN486C, GLN487C, GLN585F, GLN608C, GLN608F, GLN615C, GLN646C, GLN688F, GLU348C, GLU397C, GLU515C, GLU531C, GLU531F, GLU546C, GLU563F, GLU564F, GLU565F, GLU575C, GLU575F, GLU698F, GLY275C, GLY281C, GLY306F, GLY356C, GLY361C, GLY377C, GLY384C, GLY389C, GLY466F, GLY470F, GLY481C, GLY481F, GLY505C, GLY513C, GLY513F, GLY521C, GLY539C, GLY544C, GLY549C, GLY578F, GLY594F, GLY600C, GLY600F, GLY604F, GLY616C, GLY627C, GLY627F, GLY636C, GLY637C, GLY639C, HIS272C, HIS289C, HIS359C, HIS422F, HIS427F, HIS527F, HIS597C, HIS597F, HIS624C, HIS628C, HIS628F, HIS630C, HIS630F, ILE260C, ILE373C, ILE439F, ILE517C, ILE518C, ILE542C, ILE560C, ILE566F, ILE618C, ILE622C, LEU351C, LEU355C, LEU379C, LEU381C, LEU396C, LEU431F, LEU434F, LEU438F, LEU443F, LEU446F, LEU461F, LEU462F, LEU479F, LEU511C, LEU555C, LEU602C, LEU602F, LEU634C, LEU640C, LEU648C, LEU732F, LEU736F, LYS258C, LYS459F, LYS476F, LYS491C, LYS493C, LYS508C, LYS528C, LYS528F, LYS533C, LYS545C, LYS567F, LYS621C, LYS641C, LYS693F, MET435F, MET471F, MET524C, MET537C, MET541C, MET559C, MET599C, MET599F, MET605C, MET605F, MET635C, PHE274C, PHE288C, PHE344C, PHE393C, PHE399C, PHE421F, PHE463F, PHE501C, PHE534C, PHE535C, PHE543C, PHE577C, PHE577F, PHE584C, PHE584F, PHE629C, PHE629F, PHE638C, PRO279C, PRO352C, PRO374C, PRO400C, PRO420F, PRO437F, PRO468F, PRO475F, PRO480F, PRO482C, PRO482F, PRO520C, PRO536C, PRO571F, PRO591F, PRO603C, PRO603F, PRO617C, PRO623C, PRO631C, PRO633C, PRO697F, PRO735F, SER261C, SER262C, SER268C, SER277C, SER357C, SER391C, SER392C, SER423F, SER424F, SER428F, SER430F, SER464F, SER467F, SER472F, SER490C, SER499C, SER507C, SER516C, SER538C, SER547C, SER551C, SER586F, SER587F, SER588F, SER632C, SER632F, SER692F, THR265C, THR278C, THR380C, THR449F, THR492C, THR494C, THR502C, THR504C, THR522C, THR553C, THR561C, THR569F, THR574C, THR579F, THR589F, THR593F, THR625C, THR733F, TRP280C, TRP305F, TRP478F, TRP503C, TRP607C, TRP607F, TRP619C, TRP695F, TYR252C, TYR273C, TYR276C, TYR282C, TYR349C, TYR353C, TYR376C, TYR378C, TYR394C, TYR398C, TYR425F, TYR442F, TYR444F, TYR445F, TYR484C, TYR509C, TYR613C, TYR731F, VAL354C, VAL388C, VAL473F, VAL489C, VAL540C, VAL558C, VAL572C, VAL572F, VAL580F, VAL582F, VAL596C, VAL596F, VAL606F, VAL699F
• C-I: ALA267I, ALA358I, ALA426C, ALA456C, ALA469C, ALA506I, ALA523C, ALA523I, ALA525C, ALA548I, ALA550I, ALA554I, ALA568C, ALA573I, ALA581C, ALA592C, ALA598C, ALA598I, ALA601C, ALA601I, ALA620I, ARG287I, ARG390I, ARG433C, ARG448C, ARG465C, ARG485C, ARG485I, ARG488I, ARG514I, ARG576C, ARG576I, ARG610C, ARG610I, ARG694C, ARG730C, ARG734C, ASN253I, ASN269I, ASN271I, ASN286I, ASN382I, ASN383I, ASN436C, ASN447C, ASN451C, ASN458C, ASN477C, ASN496I, ASN497I, ASN498I, ASN500I, ASN510C, ASN510I, ASN512I, ASN519I, ASN552I, ASN557I, ASN570C, ASN570I, ASN583C, ASN691C, ASN696C, ASP270I, ASP284I, ASP346I, ASP432C, ASP440C, ASP460C, ASP495I, ASP529C, ASP530C, ASP556I, ASP562C, ASP590C, ASP595C, ASP595I, ASP609C, ASP609I, ASP611C, ASP626I, CYS362I, CYS395I, CYS483I, GLN350I, GLN360I, GLN375I, GLN386I, GLN429C, GLN441C, GLN450C, GLN452C, GLN457C, GLN474C, GLN486I, GLN487I, GLN585C, GLN608C, GLN608I, GLN615I, GLN646I, GLN688C, GLU348I, GLU397I, GLU515I, GLU531C, GLU531I, GLU546I, GLU563C, GLU564C, GLU565C, GLU575C, GLU575I, GLU698C, GLY275I, GLY281I, GLY306C, GLY356I, GLY361I, GLY377I, GLY384I, GLY389I, GLY466C, GLY470C, GLY481C, GLY481I, GLY505I, GLY513C, GLY513I, GLY521I, GLY539I, GLY544I, GLY549I, GLY578C, GLY594C, GLY600C, GLY600I, GLY604C, GLY616I, GLY627C, GLY627I, GLY636I, GLY637I, GLY639I, HIS272I, HIS289I, HIS359I, HIS422C, HIS427C, HIS527C, HIS597C, HIS597I, HIS624I, HIS628C, HIS628I, HIS630C, HIS630I, ILE260I, ILE373I, ILE439C, ILE517I, ILE518I, ILE542I, ILE560I, ILE566C, ILE618I, ILE622I, LEU351I, LEU355I, LEU379I, LEU381I, LEU396I, LEU431C, LEU434C, LEU438C, LEU443C, LEU446C, LEU461C, LEU462C, LEU479C, LEU511I, LEU555I, LEU602C, LEU602I, LEU634I, LEU640I, LEU648I, LEU732C, LEU736C, LYS258I, LYS459C, LYS476C, LYS491I, LYS493I, LYS508I, LYS528C, LYS528I, LYS533I, LYS545I, LYS567C, LYS621I, LYS641I, LYS693C, MET435C, MET471C, MET524I, MET537I, MET541I, MET559I, MET599C, MET599I, MET605C, MET605I, MET635I, PHE274I, PHE288I, PHE344I, PHE393I, PHE399I, PHE421C, PHE463C, PHE501I, PHE534I, PHE535I, PHE543I, PHE577C, PHE577I, PHE584C, PHE584I, PHE629C, PHE629I, PHE638I, PRO279I, PRO352I, PRO374I, PRO400I, PRO420C, PRO437C, PRO468C, PRO475C, PRO480C, PRO482C, PRO482I, PRO520I, PRO536I, PRO571C, PRO591C, PRO603C, PRO603I, PRO617I, PRO623I, PRO631I, PRO633I, PRO697C, PRO735C, SER261I, SER262I, SER268I, SER277I, SER357I, SER391I, SER392I, SER423C, SER424C, SER428C, SER430C, SER464C, SER467C, SER472C, SER490I, SER499I, SER507I, SER516I, SER538I, SER547I, SER551I, SER586C, SER587C, SER588C, SER632C, SER632I, SER692C, THR265I, THR278I, THR380I, THR449C, THR492I, THR494I, THR502I, THR504I, THR522I, THR553I, THR561I, THR569C, THR574I, THR579C, THR589C, THR593C, THR625I, THR733C, TRP280I, TRP305C, TRP478C, TRP503I, TRP607C, TRP607I, TRP619I, TRP695C, TYR252I, TYR273I, TYR276I, TYR282I, TYR349I, TYR353I, TYR376I, TYR378I, TYR394I, TYR398I, TYR425C, TYR442C, TYR444C, TYR445C, TYR484I, TYR509I, TYR613I, TYR731C, VAL354I, VAL388I, VAL473C, VAL489I, VAL540I, VAL558I, VAL572C, VAL572I, VAL580C, VAL582C, VAL596C, VAL596I, VAL606C, VAL699C
• D-F: ALA218F, ALA224D, ALA248D, ALA263F, ALA334D, ALA334F, ALA368D, ALA387F, ALA656F, ALA660F, ALA664F, ALA668F, ALA706D, ALA709D, ARG245D, ARG287D, ARG295D, ARG299D, ARG390F, ARG405D, ARG405F, ASN223D, ASN227D, ASN253D, ASN253F, ASN254D, ASN318D, ASN327D, ASN327F, ASN335D, ASN335F, ASN336D, ASN336F, ASN382F, ASN383F, ASN408D, ASN408F, ASN409D, ASN409F, ASN651D, ASN657F, ASN704D, ASN710D, ASN717D, ASN718D, ASP219D, ASP219F, ASP231D, ASP296D, ASP328F, ASP369D, ASP712D, ASP716D, CYS230D, CYS362D, CYS395F, GLN259F, GLN320D, GLN342F, GLN350F, GLN360D, GLN375D, GLN386F, GLN402F, GLN673D, GLN673F, GLN678D, GLU323D, GLU323F, GLU397F, GLU546D, GLU661F, GLY217F, GLY220D, GLY220F, GLY222D, GLY222F, GLY226D, GLY275F, GLY329D, GLY361D, GLY384F, GLY389F, GLY407D, GLY407F, GLY677D, GLY719D, HIS229D, HIS255F, HIS291D, HIS359D, ILE240D, ILE260F, ILE319D, ILE319F, ILE333D, ILE373D, ILE671F, LEU249D, LEU256F, LEU337D, LEU337F, LEU381F, LEU396F, LEU404F, LEU720D, LYS258F, LYS322D, LYS650F, LYS666F, LYS707D, MET372D, MET403F, PHE274F, PHE292D, PHE317D, PHE344F, PHE366D, PHE371D, PHE393F, PHE399F, PHE662F, PHE667F, PHE670F, PHE713D, PRO250D, PRO279F, PRO294D, PRO364D, PRO365D, PRO367D, PRO374D, PRO400F, PRO653F, PRO655F, PRO658F, PRO659F, SER225D, SER232D, SER243D, SER261F, SER277F, SER293D, SER339F, SER385F, SER391F, SER392F, SER401F, SER663F, SER669F, SER675D, SER703D, SER708D, THR233D, THR241D, THR242D, THR244D, THR246D, THR251D, THR278F, THR325D, THR325F, THR326D, THR326F, THR331D, THR332D, THR338F, THR340F, THR380F, THR406D, THR406F, THR652F, THR665F, THR672D, THR672F, THR676D, THR702D, THR714D, THR722D, TRP228D, TRP234D, TRP247D, TRP280F, TRP297D, TYR252D, TYR257F, TYR276F, TYR282D, TYR378F, TYR394F, TYR398F, TYR674D, TYR705D, TYR721D, VAL221D, VAL221F, VAL321D, VAL324D, VAL330D, VAL341F, VAL343F, VAL370D, VAL388F, VAL654F, VAL711D, VAL715D
• D-H: ALA267D, ALA358D, ALA426H, ALA456H, ALA469H, ALA506D, ALA523D, ALA523H, ALA525H, ALA548D, ALA550D, ALA554D, ALA568H, ALA573D, ALA581H, ALA592H, ALA598D, ALA598H, ALA601D, ALA601H, ALA620D, ARG287D, ARG390D, ARG433H, ARG448H, ARG465H, ARG485D, ARG485H, ARG488D, ARG514D, ARG576D, ARG576H, ARG610D, ARG610H, ARG694H, ARG730H, ARG734H, ASN253D, ASN269D, ASN271D, ASN286D, ASN382D, ASN383D, ASN436H, ASN447H, ASN451H, ASN458H, ASN477H, ASN496D, ASN497D, ASN498D, ASN500D, ASN510D, ASN510H, ASN512D, ASN519D, ASN552D, ASN557D, ASN570D, ASN570H, ASN583H, ASN691H, ASN696H, ASP270D, ASP284D, ASP346D, ASP432H, ASP440H, ASP460H, ASP495D, ASP529H, ASP530H, ASP556D, ASP562H, ASP590H, ASP595D, ASP595H, ASP609D, ASP609H, ASP611H, ASP626D, CYS362D, CYS395D, CYS483D, GLN350D, GLN360D, GLN375D, GLN386D, GLN429H, GLN441H, GLN450H, GLN452H, GLN457H, GLN474H, GLN486D, GLN487D, GLN585H, GLN608D, GLN608H, GLN615D, GLN646D, GLN688H, GLU348D, GLU397D, GLU515D, GLU531D, GLU531H, GLU546D, GLU563H, GLU564H, GLU565H, GLU575D, GLU575H, GLU698H, GLY275D, GLY281D, GLY306H, GLY356D, GLY361D, GLY377D, GLY384D, GLY389D, GLY466H, GLY470H, GLY481D, GLY481H, GLY505D, GLY513D, GLY513H, GLY521D, GLY539D, GLY544D, GLY549D, GLY578H, GLY594H, GLY600D, GLY600H, GLY604H, GLY616D, GLY627D, GLY627H, GLY636D, GLY637D, GLY639D, HIS272D, HIS289D, HIS359D, HIS422H, HIS427H, HIS527H, HIS597D, HIS597H, HIS624D, HIS628D, HIS628H, HIS630D, HIS630H, ILE260D, ILE373D, ILE439H, ILE517D, ILE518D, ILE542D, ILE560D, ILE566H, ILE618D, ILE622D, LEU351D, LEU355D, LEU379D, LEU381D, LEU396D, LEU431H, LEU434H, LEU438H, LEU443H, LEU446H, LEU461H, LEU462H, LEU479H, LEU511D, LEU555D, LEU602D, LEU602H, LEU634D, LEU640D, LEU648D, LEU732H, LEU736H, LYS258D, LYS459H, LYS476H, LYS491D, LYS493D, LYS508D, LYS528D, LYS528H, LYS533D, LYS545D, LYS567H, LYS621D, LYS641D, LYS693H, MET435H, MET471H, MET524D, MET537D, MET541D, MET559D, MET599D, MET599H, MET605D, MET605H, MET635D, PHE274D, PHE288D, PHE344D, PHE393D, PHE399D, PHE421H, PHE463H, PHE501D, PHE534D, PHE535D, PHE543D, PHE577D, PHE577H, PHE584D, PHE584H, PHE629D, PHE629H, PHE638D, PRO279D, PRO352D, PRO374D, PRO400D, PRO420H, PRO437H, PRO468H, PRO475H, PRO480H, PRO482D, PRO482H, PRO520D, PRO536D, PRO571H, PRO591H, PRO603D, PRO603H, PRO617D, PRO623D, PRO631D, PRO633D, PRO697H, PRO735H, SER261D, SER262D, SER268D, SER277D, SER357D, SER391D, SER392D, SER423H, SER424H, SER428H, SER430H, SER464H, SER467H, SER472H, SER490D, SER499D, SER507D, SER516D, SER538D, SER547D, SER551D, SER586H, SER587H, SER588H, SER632D, SER632H, SER692H, THR265D, THR278D, THR380D, THR449H, THR492D, THR494D, THR502D, THR504D, THR522D, THR553D, THR561D, THR569H, THR574D, THR579H, THR589H, THR593H, THR625D, THR733H, TRP280D, TRP305H, TRP478H, TRP503D, TRP607D, TRP607H, TRP619D, TRP695H, TYR252D, TYR273D, TYR276D, TYR282D, TYR349D, TYR353D, TYR376D, TYR378D, TYR394D, TYR398D, TYR425H, TYR442H, TYR444H, TYR445H, TYR484D, TYR509D, TYR613D, TYR731H, VAL354D, VAL388D, VAL473H, VAL489D, VAL540D, VAL558D, VAL572D, VAL572H, VAL580H, VAL582H, VAL596D, VAL596H, VAL606H, VAL699H
• D-I: ALA368D, ALA368I, ALA706D, ALA706I, ARG245D, ARG245I, ARG295D, ARG295I, ARG299D, ARG299I, ARG694D, ARG694I, ARG725D, ARG725I, ASN302D, ASN302I, ASN303D, ASN303I, ASN304D, ASN304I, ASN691D, ASN691I, ASN696D, ASN696I, ASN704D, ASN704I, ASP231D, ASP231I, ASP296D, ASP296I, ASP529D, ASP529I, ASP530D, ASP530I, ASP532D, ASP532I, ASP712D, ASP712I, CYS230D, CYS230I, GLN298D, GLN298I, GLN700D, GLN700I, GLU564D, GLU564I, GLU690D, GLU690I, GLU698D, GLU698I, GLU723D, GLU723I, GLY236D, GLY236I, HIS289D, HIS289I, HIS291D, HIS291I, ILE301D, ILE301I, ILE727D, ILE727I, LEU614D, LEU614I, LEU732D, LEU732I, LYS689D, LYS689I, LYS693D, LYS693I, LYS707D, LYS707I, PHE292D, PHE292I, PHE366D, PHE366I, PHE713D, PHE713I, PRO294D, PRO294I, PRO364D, PRO364I, PRO365D, PRO365I, PRO367D, PRO367I, PRO697D, PRO697I, PRO724D, PRO724I, SER232D, SER232I, SER243D, SER243I, SER293D, SER293I, SER692D, SER692I, SER703D, SER703I, THR233D, THR233I, THR702D, THR702I, THR714D, THR714I, THR733D, THR733I, TRP234D, TRP234I, TRP297D, TRP297I, TRP305D, TRP305I, TRP695D, TRP695I, TYR701D, TYR701I, TYR705D, TYR705I, TYR721D, TYR721I, TYR731D, TYR731I, VAL699D, VAL699I, VAL711D, VAL711I, VAL715D, VAL715I
• E-G: ALA267E, ALA358E, ALA426G, ALA456G, ALA469G, ALA506E, ALA523E, ALA523G, ALA525G, ALA548E, ALA550E, ALA554E, ALA568G, ALA573E, ALA581G, ALA592G, ALA598E, ALA598G, ALA601E, ALA601G, ALA620E, ARG287E, ARG390E, ARG433G, ARG448G, ARG465G, ARG485E, ARG485G, ARG488E, ARG514E, ARG576E, ARG576G, ARG610E, ARG610G, ARG694G, ARG730G, ARG734G, ASN253E, ASN269E, ASN271E, ASN286E, ASN382E, ASN383E, ASN436G, ASN447G, ASN451G, ASN458G, ASN477G, ASN496E, ASN497E, ASN498E, ASN500E, ASN510E, ASN510G, ASN512E, ASN519E, ASN552E, ASN557E, ASN570E, ASN570G, ASN583G, ASN691G, ASN696G, ASP270E, ASP284E, ASP346E, ASP432G, ASP440G, ASP460G, ASP495E, ASP529G, ASP530G, ASP556E, ASP562G, ASP590G, ASP595E, ASP595G, ASP609E, ASP609G, ASP611G, ASP626E, CYS362E, CYS395E, CYS483E, GLN350E, GLN360E, GLN375E, GLN386E, GLN429G, GLN441G, GLN450G, GLN452G, GLN457G, GLN474G, GLN486E, GLN487E, GLN585G, GLN608E, GLN608G, GLN615E, GLN646E, GLN688G, GLU348E, GLU397E, GLU515E, GLU531E, GLU531G, GLU546E, GLU563G, GLU564G, GLU565G, GLU575E, GLU575G, GLU698G, GLY275E, GLY281E, GLY306G, GLY356E, GLY361E, GLY377E, GLY384E, GLY389E, GLY466G, GLY470G, GLY481E, GLY481G, GLY505E, GLY513E, GLY513G, GLY521E, GLY539E, GLY544E, GLY549E, GLY578G, GLY594G, GLY600E, GLY600G, GLY604G, GLY616E, GLY627E, GLY627G, GLY636E, GLY637E, GLY639E, HIS272E, HIS289E, HIS359E, HIS422G, HIS427G, HIS527G, HIS597E, HIS597G, HIS624E, HIS628E, HIS628G, HIS630E, HIS630G, ILE260E, ILE373E, ILE439G, ILE517E, ILE518E, ILE542E, ILE560E, ILE566G, ILE618E, ILE622E, LEU351E, LEU355E, LEU379E, LEU381E, LEU396E, LEU431G, LEU434G, LEU438G, LEU443G, LEU446G, LEU461G, LEU462G, LEU479G, LEU511E, LEU555E, LEU602E, LEU602G, LEU634E, LEU640E, LEU648E, LEU732G, LEU736G, LYS258E, LYS459G, LYS476G, LYS491E, LYS493E, LYS508E, LYS528E, LYS528G, LYS533E, LYS545E, LYS567G, LYS621E, LYS641E, LYS693G, MET435G, MET471G, MET524E, MET537E, MET541E, MET559E, MET599E, MET599G, MET605E, MET605G, MET635E, PHE274E, PHE288E, PHE344E, PHE393E, PHE399E, PHE421G, PHE463G, PHE501E, PHE534E, PHE535E, PHE543E, PHE577E, PHE577G, PHE584E, PHE584G, PHE629E, PHE629G, PHE638E, PRO279E, PRO352E, PRO374E, PRO400E, PRO420G, PRO437G, PRO468G, PRO475G, PRO480G, PRO482E, PRO482G, PRO520E, PRO536E, PRO571G, PRO591G, PRO603E, PRO603G, PRO617E, PRO623E, PRO631E, PRO633E, PRO697G, PRO735G, SER261E, SER262E, SER268E, SER277E, SER357E, SER391E, SER392E, SER423G, SER424G, SER428G, SER430G, SER464G, SER467G, SER472G, SER490E, SER499E, SER507E, SER516E, SER538E, SER547E, SER551E, SER586G, SER587G, SER588G, SER632E, SER632G, SER692G, THR265E, THR278E, THR380E, THR449G, THR492E, THR494E, THR502E, THR504E, THR522E, THR553E, THR561E, THR569G, THR574E, THR579G, THR589G, THR593G, THR625E, THR733G, TRP280E, TRP305G, TRP478G, TRP503E, TRP607E, TRP607G, TRP619E, TRP695G, TYR252E, TYR273E, TYR276E, TYR282E, TYR349E, TYR353E, TYR376E, TYR378E, TYR394E, TYR398E, TYR425G, TYR442G, TYR444G, TYR445G, TYR484E, TYR509E, TYR613E, TYR731G, VAL354E, VAL388E, VAL473G, VAL489E, VAL540E, VAL558E, VAL572E, VAL572G, VAL580G, VAL582G, VAL596E, VAL596G, VAL606G, VAL699G
• E-H: ALA218H, ALA224E, ALA248E, ALA263H, ALA334E, ALA334H, ALA368E, ALA387H, ALA656H, ALA660H, ALA664H, ALA668H, ALA706E, ALA709E, ARG245E, ARG287E, ARG295E, ARG299E, ARG390H, ARG405E, ARG405H, ASN223E, ASN223H, ASN227E, ASN253E, ASN253H, ASN254E, ASN318E, ASN327E, ASN327H, ASN335E, ASN335H, ASN336E, ASN336H, ASN382H, ASN383H, ASN408E, ASN408H, ASN409H, ASN651E, ASN657H, ASN704E, ASN710E, ASN717E, ASN718E, ASP219E, ASP219H, ASP231E, ASP296E, ASP328E, ASP328H, ASP369E, ASP712E, ASP716E, CYS230E, CYS362E, CYS395H, GLN259H, GLN320E, GLN342H, GLN350H, GLN360E, GLN375E, GLN386H, GLN402H, GLN673E, GLN673H, GLN678E, GLU323E, GLU323H, GLU397H, GLU546E, GLU661H, GLY217H, GLY220E, GLY220H, GLY222E, GLY222H, GLY226E, GLY275H, GLY329E, GLY361E, GLY384H, GLY389H, GLY407E, GLY407H, GLY677E, GLY719E, HIS229E, HIS255H, HIS291E, HIS359E, ILE260H, ILE319E, ILE319H, ILE333E, ILE373E, ILE671H, LEU249E, LEU256H, LEU337E, LEU337H, LEU381H, LEU396H, LEU404H, LEU720E, LYS258H, LYS322E, LYS650H, LYS666H, LYS707E, MET372E, MET403H, PHE274H, PHE292E, PHE317E, PHE344H, PHE366E, PHE371E, PHE393H, PHE399H, PHE662H, PHE667H, PHE670H, PHE713E, PRO250E, PRO279H, PRO294E, PRO364E, PRO365E, PRO367E, PRO374E, PRO400H, PRO653H, PRO655H, PRO658H, PRO659H, SER225E, SER232E, SER243E, SER261H, SER277H, SER293E, SER339H, SER385H, SER391H, SER392H, SER401H, SER663H, SER669H, SER675E, SER703E, SER708E, THR233E, THR241E, THR242E, THR244E, THR246E, THR251E, THR278H, THR325E, THR325H, THR326E, THR326H, THR331E, THR332E, THR338H, THR340H, THR380H, THR406E, THR406H, THR652H, THR665H, THR672E, THR672H, THR676E, THR702E, THR714E, THR722E, TRP228E, TRP234E, TRP247E, TRP280H, TRP297E, TYR252E, TYR257H, TYR276H, TYR282E, TYR378H, TYR394H, TYR398H, TYR674E, TYR705E, TYR721E, VAL221E, VAL221H, VAL321E, VAL324E, VAL330E, VAL341H, VAL343H, VAL370E, VAL388H, VAL654H, VAL711E, VAL715E
• F-H: ALA664F, ARG465H, ASP440H, GLN441H, GLU661F, ILE439H, LEU438H, PHE662F, SER663F, THR665F, TYR442H
• F-I: ALA267F, ALA358F, ALA426I, ALA456I, ALA469I, ALA506F, ALA523F, ALA523I, ALA525I, ALA548F, ALA550F, ALA554F, ALA568I, ALA573F, ALA581I, ALA592I, ALA598F, ALA598I, ALA601F, ALA601I, ALA620F, ARG287F, ARG390F, ARG433I, ARG448I, ARG465I, ARG485F, ARG485I, ARG488F, ARG514F, ARG576F, ARG576I, ARG610F, ARG610I, ARG694I, ARG730I, ARG734I, ASN253F, ASN269F, ASN271F, ASN286F, ASN382F, ASN383F, ASN436I, ASN447I, ASN451I, ASN458I, ASN477I, ASN496F, ASN497F, ASN498F, ASN500F, ASN510F, ASN510I, ASN512F, ASN519F, ASN552F, ASN557F, ASN570F, ASN570I, ASN583I, ASN691I, ASN696I, ASP270F, ASP284F, ASP346F, ASP432I, ASP440I, ASP460I, ASP495F, ASP529I, ASP530I, ASP556F, ASP562I, ASP590I, ASP595F, ASP595I, ASP609F, ASP609I, ASP611I, ASP626F, CYS362F, CYS395F, CYS483F, GLN350F, GLN360F, GLN375F, GLN386F, GLN429I, GLN441I, GLN450I, GLN452I, GLN457I, GLN474I, GLN486F, GLN487F, GLN585I, GLN608F, GLN608I, GLN615F, GLN646F, GLN688I, GLU348F, GLU397F, GLU515F, GLU531F, GLU531I, GLU546F, GLU563I, GLU564I, GLU565I, GLU575F, GLU575I, GLU698I, GLY275F, GLY281F, GLY306I, GLY356F, GLY361F, GLY377F, GLY384F, GLY389F, GLY466I, GLY470I, GLY481F, GLY481I, GLY505F, GLY513F, GLY513I, GLY521F, GLY539F, GLY544F, GLY549F, GLY578I, GLY594I, GLY600F, GLY600I, GLY604I, GLY616F, GLY627F, GLY627I, GLY636F, GLY637F, GLY639F, HIS272F, HIS289F, HIS359F, HIS422I, HIS427I, HIS527I, HIS597F, HIS597I, HIS624F, HIS628F, HIS628I, HIS630F, HIS630I, ILE260F, ILE373F, ILE439I, ILE517F, ILE518F, ILE542F, ILE560F, ILE566I, ILE618F, ILE622F, LEU351F, LEU355F, LEU379F, LEU381F, LEU396F, LEU431I, LEU434I, LEU438I, LEU443I, LEU446I, LEU461I, LEU462I, LEU479I, LEU511F, LEU555F, LEU602F, LEU602I, LEU634F, LEU640F, LEU648F, LEU732I, LEU736I, LYS258F, LYS459I, LYS476I, LYS491F, LYS493F, LYS508F, LYS528F, LYS528I, LYS533F, LYS545F, LYS567I, LYS621F, LYS641F, LYS693I, MET435I, MET471I, MET524F, MET537F, MET541F, MET559F, MET599F, MET599I, MET605F, MET605I, MET635F, PHE274F, PHE288F, PHE344F, PHE393F, PHE399F, PHE421I, PHE463I, PHE501F, PHE534F, PHE535F, PHE543F, PHE577F, PHE577I, PHE584F, PHE584I, PHE629F, PHE629I, PHE638F, PRO279F, PRO352F, PRO374F, PRO400F, PRO420I, PRO437I, PRO468I, PRO475I, PRO480I, PRO482F, PRO482I, PRO520F, PRO536F, PRO571I, PRO591I, PRO603F, PRO603I, PRO617F, PRO623F, PRO631F, PRO633F, PRO697I, PRO735I, SER261F, SER262F, SER268F, SER277F, SER357F, SER391F, SER392F, SER423I, SER424I, SER428I, SER430I, SER464I, SER467I, SER472I, SER490F, SER499F, SER507F, SER516F, SER538F, SER547F, SER551F, SER586I, SER587I, SER588I, SER632F, SER632I, SER692I, THR265F, THR278F, THR380F, THR449I, THR492F, THR494F, THR502F, THR504F, THR522F, THR553F, THR561F, THR569I, THR574F, THR579I, THR589I, THR593I, THR625F, THR733I, TRP280F, TRP305I, TRP478I, TRP503F, TRP607F, TRP607I, TRP619F, TRP695I, TYR252F, TYR273F, TYR276F, TYR282F, TYR349F, TYR353F, TYR376F, TYR378F, TYR394F, TYR398F, TYR425I, TYR442I, TYR444I, TYR445I, TYR484F, TYR509F, TYR613F, TYR731I, VAL354F, VAL388F, VAL473I, VAL489F, VAL540F, VAL558F, VAL572F, VAL572I, VAL580I, VAL582I, VAL596F, VAL596I, VAL606I, VAL699I
• G-H: ALA664H, ARG465G, ASP440G, GLN441G, GLU661H, ILE439G, LEU438G, PHE662H, SER663H, THR665H, TYR442G
• G-J: ALA218G, ALA218J, ALA224J, ALA248J, ALA263G, ALA334G, ALA334J, ALA368J, ALA387G, ALA656G, ALA660G, ALA664G, ALA668G, ALA706J, ALA709J, ARG245J, ARG287J, ARG295J, ARG299J, ARG390G, ARG405G, ARG405J, ASN223G, ASN223J, ASN227J, ASN253G, ASN253J, ASN254J, ASN318J, ASN327G, ASN327J, ASN335G, ASN335J, ASN336G, ASN336J, ASN382G, ASN383G, ASN408G, ASN408J, ASN409G, ASN651J, ASN657G, ASN704J, ASN710J, ASN717J, ASN718J, ASP219G, ASP219J, ASP231J, ASP296J, ASP328G, ASP328J, ASP369J, ASP712J, ASP716J, CYS230J, CYS362J, CYS395G, GLN259G, GLN320J, GLN342G, GLN350G, GLN360J, GLN375J, GLN386G, GLN402G, GLN673G, GLN673J, GLN678J, GLU323G, GLU323J, GLU397G, GLU546J, GLU661G, GLY217G, GLY220G, GLY220J, GLY222G, GLY222J, GLY226J, GLY275G, GLY329J, GLY361J, GLY384G, GLY389G, GLY407G, GLY407J, GLY677J, GLY719J, HIS229J, HIS255G, HIS291J, HIS359J, ILE260G, ILE319G, ILE319J, ILE333J, ILE373J, ILE671G, LEU249J, LEU256G, LEU337G, LEU337J, LEU381G, LEU396G, LEU404G, LEU720J, LYS258G, LYS322J, LYS650G, LYS666G, LYS707J, MET372J, MET403G, PHE274G, PHE292J, PHE317J, PHE344G, PHE366J, PHE371J, PHE393G, PHE399G, PHE662G, PHE667G, PHE670G, PHE713J, PRO250J, PRO279G, PRO294J, PRO364J, PRO365J, PRO367J, PRO374J, PRO400G, PRO653G, PRO655G, PRO658G, PRO659G, SER225G, SER225J, SER232J, SER243J, SER261G, SER277G, SER293J, SER339G, SER385G, SER391G, SER392G, SER401G, SER663G, SER669G, SER675J, SER703J, SER708J, THR233J, THR241J, THR242J, THR244J, THR246J, THR251J, THR278G, THR325G, THR325J, THR326G, THR326J, THR331J, THR332J, THR338G, THR340G, THR380G, THR406G, THR406J, THR652G, THR665G, THR672G, THR672J, THR676J, THR702J, THR714J, THR722J, TRP228J, TRP234J, TRP247J, TRP280G, TRP297J, TYR252J, TYR257G, TYR276G, TYR282J, TYR378G, TYR394G, TYR398G, TYR674J, TYR705J, TYR721J, VAL221G, VAL221J, VAL321J, VAL324J, VAL330J, VAL341G, VAL343G, VAL370J, VAL388G, VAL654G, VAL711J, VAL715J