3NAH

crystal structures and functional analysis of murine norovirus rna- dependent rna polymerase

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 118
  • Norm. En. per Res.: -2.5834
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-8.5958	-20.4031	-111.973	-140.9719	75	5	0	5630	2	21	22
A-C	0.0	0.0	-0.0475	-0.0475	6	0	0	26	0	2	0
B-C	-15.021	-42.7126	-247.104	-304.8376	118	13	8	10463	0	34	25

Interface residues

• A-B: ALA138A, ALA138B, ALA147B, ALA275B, ALA437A, ARG200B, ASN151B, ASN152B, ASN425A, ASN428A, ASP133A, ASP133B, ASP142B, ASP145B, ASP273B, GLN104B, GLN129A, GLN146B, GLN427A, GLN438A, GLN471A, GLU155B, GLU271B, GLU431A, GLY136A, GLY136B, GLY141A, GLY141B, GLY144B, GLY157B, GLY423A, GLY435A, GLY473A, HIS149B, HIS426A, HIS436A, ILE140A, ILE140B, ILE474A, LEU143B, LEU274B, LEU433A, LYS105B, LYS110B, LYS111B, LYS128A, LYS130A, LYS132A, LYS158B, LYS29A, MET153B, MET156B, PHE109B, PHE139A, PHE139B, PRO103B, PRO106B, PRO270B, PRO272B, PRO424A, PRO434A, SER131A, SER137A, SER137B, SER472A, THR108B, THR135A, THR135B, THR148B, THR432A, TRP107B, TRP134A, TRP134B, TRP33A, TYR154B
• A-C: ARG482C, GLU475A, GLU475C, MET476A, VAL477A, VAL477C
• B-C: ALA208C, ALA233B, ALA233C, ALA236B, ALA236C, ALA92C, ARG234B, ARG234C, ARG239B, ARG239C, ARG480B, ARG482B, ARG482C, ARG486B, ARG486C, ARG489B, ARG489C, ARG96B, ARG96C, ASN216B, ASN216C, ASN225B, ASN225C, ASN237B, ASN237C, ASN95B, ASN95C, ASN99B, ASN99C, ASP227B, ASP227C, ASP333B, ASP333C, ASP401B, ASP401C, GLN104B, GLN337B, GLN337C, GLN402B, GLN402C, GLU102B, GLU102C, GLU211B, GLU211C, GLU226B, GLU226C, GLU338B, GLU338C, GLU340B, GLU340C, GLU98B, GLU98C, GLY228B, GLY228C, GLY400B, GLY400C, GLY404B, GLY404C, GLY491B, GLY491C, HIS235B, HIS235C, HIS241C, ILE214B, ILE214C, ILE231B, ILE231C, ILE334B, ILE334C, ILE93C, LEU101B, LEU101C, LEU268C, LEU388B, LEU388C, LEU485B, LEU485C, LEU97B, LEU97C, MET336B, MET336C, PHE215B, PHE215C, PHE230B, PHE230C, PHE232B, PHE232C, PHE238B, PHE238C, PHE403B, PHE403C, PHE490B, PHE490C, PRO103B, PRO103C, PRO217C, PRO229B, PRO229C, PRO332C, SER339B, SER339C, SER483B, SER483C, THR100B, THR100C, THR212B, THR212C, THR492B, THR492C, TRP317C, TRP405B, TRP405C, TRP487B, TRP487C, TYR406B, TYR406C, VAL335C, VAL488C