3N9U

crystal structure of the complex between the 25 kda subunit and the 59 kda subunit (rrm domain) of human cleavage factor im

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 53
  • Norm. En. per Res.: -5.152
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.9336	27.8727	-367.296	-371.3569	141	9	12	14984	3	30	33
A-C	0.0	0.0	-69.3964	-69.3964	28	0	0	2128	0	5	3
A-I	-45.613	-28.2919	-130.318	-204.2228	49	6	0	4565	2	16	14
B-C	-55.6921	-63.2095	-154.152	-273.0536	53	7	0	5121	7	18	19
B-I	0.0	0.0	-84.1241	-84.1241	31	2	0	2706	0	7	2

Interface residues

• A-B: ALA163A, ALA163B, ALA205A, ALA205B, ARG221A, ARG221B, ARG35A, ARG35B, ARG78A, ARG90A, ARG90B, ASN147A, ASN147B, ASN223A, ASN223B, ASP116A, ASP142A, ASP142B, ASP143A, ASP143B, ASP203A, ASP203B, CYS144A, CYS144B, GLN157A, GLN157B, GLN178A, GLN178B, GLN217A, GLN217B, GLN27B, GLU117A, GLU117B, GLU200A, GLU200B, GLU34A, GLU34B, GLU88A, GLU88B, GLY146A, GLY146B, GLY209A, GLY209B, HIS164A, HIS164B, HIS171A, HIS171B, HIS89A, HIS89B, HIS93A, HIS93B, ILE141A, ILE141B, ILE145A, ILE145B, ILE161A, ILE161B, ILE165A, ILE165B, ILE211A, ILE211B, ILE37A, ILE37B, LEU121A, LEU174A, LEU174B, LEU176A, LEU176B, LEU198A, LEU198B, LEU201A, LEU201B, LEU215A, LEU215B, LEU218A, LEU218B, LEU219A, LEU219B, LEU31A, LEU31B, LEU33A, LEU33B, LEU91A, LEU91B, LYS122A, LYS167A, LYS172A, LYS172B, LYS173A, LYS173B, LYS29B, PHE175A, PHE175B, PHE199A, PHE199B, PHE222A, PHE222B, PHE224A, PHE224B, PRO156A, PRO156B, PRO159A, PRO159B, PRO162A, PRO162B, PRO168A, PRO197A, PRO197B, PRO210A, PRO210B, PRO216A, PRO216B, PRO30B, PRO92A, PRO92B, SER213A, SER213B, SER214A, SER214B, SER220A, SER220B, THR166A, THR166B, THR32A, THR32B, THR36A, THR36B, TRP148A, TRP148B, TRP149A, TRP149B, TYR158A, TYR158B, TYR160A, TYR160B, TYR202A, TYR202B, TYR226A, TYR226B, VAL118A, VAL140A
• A-C: ALA120C, ARG119C, ARG90A, ASN118C, ASN121C, ASN151C, ASN204A, ASP203A, GLN123C, GLN96C, GLU200A, GLU88A, GLY122C, HIS89A, HIS93A, LEU198A, LEU201A, LEU91A, PHE199A, PRO197A, PRO216A, SER124C, SER90C, THR93C, THR94C, TRP91C, TRP92C, TYR202A
• A-I: ALA116I, ALA120I, ALA128I, ALA163A, ARG103I, ARG119I, ARG68A, ASN118I, ASN121I, ASN152A, ASP95I, GLN100I, GLN123I, GLN157A, GLN96I, GLN97I, GLU112I, GLU117I, GLU154A, GLY122I, GLY126I, HIS164A, ILE161A, ILE165A, ILE99I, LEU113I, LEU98I, LYS114I, LYS125I, LYS167A, LYS169A, PHE115I, PHE153A, PRO151A, PRO155A, PRO156A, PRO159A, PRO162A, PRO168A, SER124I, SER90I, THR166A, THR93I, THR94I, TRP91I, TRP92I, TYR127I, TYR158A, TYR160A
• B-C: ALA116C, ALA120C, ALA128C, ALA163B, ARG119C, ARG68B, ASN118C, ASN121C, ASN151C, ASN152B, ASP72B, ASP95C, GLN123C, GLN157B, GLN96C, GLN97C, GLU112C, GLU117C, GLU154B, GLY122C, GLY126C, HIS164B, ILE161B, ILE165B, ILE99C, LEU113C, LEU98C, LYS114C, LYS125C, LYS167B, LYS169B, PHE115C, PHE153B, PHE71B, PHE89C, PRO151B, PRO155B, PRO156B, PRO159B, PRO162B, PRO168B, SER124C, SER90C, THR166B, THR93C, THR94C, TRP91C, TRP92C, TYR127C, TYR158B, TYR160B, VAL111C, VAL131C
• B-I: ALA120I, ARG119I, ARG90B, ASN118I, ASN121I, ASN151I, ASN204B, ASP203B, ASP95I, GLN123I, GLN96I, GLN97I, GLU200B, GLU88B, GLY122I, HIS89B, HIS93B, LEU198B, LEU201B, LEU91B, PHE199B, PRO197B, PRO216B, PRO92B, SER124I, SER90I, THR93I, THR94I, TRP91I, TRP92I, TYR202B