3N50

human early b-cell factor 3 (ebf3) ipt/tig and hlhlh domains

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 160
  • Norm. En. per Res.: -4.2231
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-11.6084	-109.5238	-450.482	-571.6142	145	16	40	21314	9	45	34
A-C	-29.585	10.567	-160.291	-179.309	71	11	0	5630	0	2	10
A-E	0.0	0.0	-57.8629	-57.8629	41	2	0	2384	0	6	9
A-F	0.0	6.3233	-0.3129	6.0104	3	0	0	56	0	3	3
B-E	0.0	0.0	-0.0006	-0.0006	2	0	0	2	0	0	1
C-D	-16.7794	-129.6977	-482.068	-628.5451	155	20	43	23413	8	53	40
C-E	-9.6275	4.819	-120.346	-125.1545	58	9	1	4910	4	10	16
C-F	0.0	0.0	-0.0237	-0.0237	4	0	0	22	0	1	1
E-F	-33.2574	-134.1855	-508.261	-675.704	160	22	41	23985	9	52	38

Interface residues

• A-B: ALA258A, ALA258B, ALA270A, ALA301A, ALA301B, ALA338A, ALA374A, ALA374B, ALA375A, ALA375B, ALA380A, ALA380B, ALA396B, ALA397B, ALA400B, ARG303A, ARG303B, ARG350A, ARG350B, ARG357A, ARG357B, ARG364B, ARG373A, ARG373B, ARG395B, ASN340B, ASN387B, ASN388B, ASP277A, ASP277B, ASP345A, ASP345B, ASP376A, ASP376B, ASP398B, GLN349A, GLN349B, GLN352A, GLN352B, GLN389B, GLU263A, GLU341A, GLU341B, GLU368A, GLU368B, GLU379A, GLU379B, GLU401B, GLY264A, GLY276A, GLY276B, GLY347A, GLY347B, GLY383A, HIS300A, HIS300B, HIS358A, ILE256A, ILE256B, ILE259A, ILE259B, ILE273A, ILE273B, ILE274A, ILE274B, ILE275A, ILE275B, ILE297A, ILE297B, ILE302A, ILE302B, ILE344A, ILE344B, ILE355A, ILE355B, ILE391B, ILE392B, ILE399B, LEU339A, LEU339B, LEU351A, LEU351B, LEU365B, LEU370A, LEU370B, LEU371A, LEU371B, LEU377A, LEU377B, LEU381A, LEU381B, LEU393B, LEU403B, LYS257A, LYS257B, LYS353A, LYS353B, LYS367A, LYS367B, LYS372A, LYS372B, LYS394B, MET384A, MET384B, PHE348A, PHE348B, PRO261A, PRO261B, PRO299A, PRO299B, PRO342A, PRO342B, PRO356A, PRO356B, PRO366A, PRO366B, PRO385B, SER260A, SER260B, SER262A, SER262B, THR267A, THR271A, THR271B, THR298A, THR298B, THR337A, THR343A, THR343B, TRP265A, TYR346A, TYR346B, TYR382A, TYR382B, TYR404B, VAL272A, VAL272B, VAL304A, VAL335A, VAL354A, VAL354B, VAL369A, VAL369B, VAL378A, VAL378B
• A-C: ALA270A, ALA270C, ALA338A, ALA338C, ARG303A, ARG303C, ARG309A, ARG309C, ASN340C, ASP281A, ASP281C, GLN284A, GLN284C, GLN305A, GLN305C, GLU295A, GLU295C, GLY268A, GLY268C, GLY269A, GLY269C, GLY282A, GLY282C, HIS310A, HIS310C, ILE311A, ILE311C, LEU283C, LEU291A, LEU291C, LEU339C, LYS322A, LYS322C, MET290A, MET290C, PHE287A, PHE287C, PRO307A, PRO307C, PRO308A, PRO308C, PRO312A, PRO312C, SER294A, SER294C, THR266A, THR266C, THR267A, THR267C, THR271A, THR271C, THR289A, THR289C, THR306A, THR306C, THR337C, TRP265A, TRP265C, TRP293A, TRP293C, TYR321C, TYR336A, TYR336C, VAL285A, VAL285C, VAL286A, VAL286C, VAL292A, VAL292C, VAL304A, VAL304C
• A-E: ALA270E, ALA338A, ARG309A, ARG309E, ARG364A, ASN340A, ASP345A, GLN305E, GLN349A, GLU341A, GLU368E, GLY268E, GLY269E, HIS310A, HIS310E, ILE311A, ILE311E, ILE344A, LEU291E, LEU339A, LYS353A, LYS367A, MET290E, PHE348A, PRO307E, PRO308E, PRO312A, PRO342A, PRO362A, THR266A, THR266E, THR267A, THR267E, THR289E, THR306E, THR337A, THR343A, TRP265A, TRP265E, TYR346A, VAL292E
• A-F: GLU341F, GLU363A, THR343F
• B-E: HIS310E, ILE344B
• C-D: ALA258C, ALA258D, ALA270C, ALA301C, ALA301D, ALA338C, ALA374C, ALA374D, ALA375C, ALA375D, ALA380C, ALA380D, ALA396D, ALA397C, ALA397D, ALA400C, ALA400D, ALA402C, ARG303C, ARG303D, ARG350C, ARG350D, ARG357D, ARG364D, ARG373C, ARG373D, ARG395D, ASN340D, ASN387D, ASN388D, ASP277C, ASP277D, ASP345C, ASP345D, ASP376C, ASP376D, ASP398C, ASP398D, CYS255D, GLN349C, GLN349D, GLN352C, GLN352D, GLN389D, GLU263C, GLU341C, GLU341D, GLU368C, GLU368D, GLU379C, GLU379D, GLU401C, GLU401D, GLY264C, GLY276C, GLY276D, GLY347C, GLY347D, GLY383C, GLY383D, HIS300C, HIS300D, HIS358C, HIS358D, ILE256C, ILE256D, ILE259C, ILE259D, ILE273C, ILE273D, ILE274C, ILE274D, ILE275C, ILE275D, ILE297C, ILE297D, ILE302C, ILE302D, ILE344C, ILE344D, ILE355C, ILE355D, ILE391D, ILE392C, ILE392D, ILE399C, ILE399D, LEU339C, LEU339D, LEU351C, LEU351D, LEU365D, LEU370C, LEU370D, LEU371C, LEU371D, LEU377C, LEU377D, LEU381C, LEU381D, LEU393D, LEU403C, LEU403D, LYS257C, LYS257D, LYS353C, LYS353D, LYS367C, LYS367D, LYS372C, LYS372D, LYS394C, LYS394D, MET384C, MET384D, PHE348C, PHE348D, PRO261C, PRO261D, PRO299C, PRO299D, PRO342C, PRO342D, PRO356C, PRO356D, PRO359D, PRO366C, PRO366D, SER260C, SER260D, SER262C, SER262D, THR271C, THR271D, THR298C, THR298D, THR337C, THR343C, THR343D, TRP265C, TYR346C, TYR346D, TYR382C, TYR382D, TYR404D, VAL272C, VAL272D, VAL304D, VAL335C, VAL354C, VAL354D, VAL369C, VAL369D, VAL378C, VAL378D
• C-E: ALA330E, ALA338C, ALA338E, ARG309C, ARG309E, ARG333E, ARG350C, ARG357C, ARG364C, ASN340C, ASN340E, ASP345C, CYS327E, GLN349C, GLN352C, GLU263E, GLU316E, GLU341C, GLU341E, GLU363C, GLY313C, GLY313E, GLY329E, GLY332E, HIS310C, HIS310E, ILE311C, ILE311E, ILE344C, ILE344E, LEU339C, LEU339E, LEU365C, LEU370C, LYS328E, LYS367C, PHE334E, PHE348C, PRO312C, PRO312E, PRO331E, PRO342C, PRO342E, PRO362C, THR266C, THR266E, THR267C, THR318E, THR337E, THR343C, THR343E, TYR336E, TYR346C, VAL314C, VAL314E, VAL315C, VAL315E, VAL335E
• C-F: PRO342C, PRO362F, PRO366F, THR343C
• E-F: ALA258E, ALA258F, ALA270E, ALA301E, ALA301F, ALA338E, ALA374E, ALA374F, ALA375E, ALA375F, ALA380E, ALA380F, ALA396F, ALA397E, ALA397F, ALA400E, ALA400F, ALA402E, ARG303E, ARG303F, ARG350E, ARG350F, ARG357E, ARG357F, ARG364F, ARG373E, ARG373F, ARG395F, ASN278E, ASN340F, ASN387F, ASN388F, ASP277E, ASP277F, ASP345E, ASP345F, ASP376E, ASP376F, ASP398E, ASP398F, GLN305F, GLN349E, GLN349F, GLN352E, GLN352F, GLN389F, GLU263E, GLU341E, GLU341F, GLU368E, GLU368F, GLU379E, GLU379F, GLU390F, GLU401E, GLU401F, GLY264E, GLY276E, GLY276F, GLY347E, GLY347F, GLY383E, HIS300E, HIS300F, HIS358E, HIS358F, ILE256E, ILE256F, ILE259E, ILE259F, ILE273E, ILE273F, ILE274E, ILE274F, ILE275E, ILE275F, ILE297E, ILE297F, ILE302E, ILE302F, ILE344E, ILE344F, ILE355E, ILE355F, ILE391E, ILE391F, ILE392F, ILE399E, ILE399F, LEU339E, LEU339F, LEU351E, LEU351F, LEU365F, LEU370E, LEU370F, LEU371E, LEU371F, LEU377E, LEU377F, LEU381E, LEU381F, LEU393F, LEU403E, LEU403F, LYS257E, LYS257F, LYS353E, LYS353F, LYS367E, LYS367F, LYS372E, LYS372F, LYS394E, LYS394F, MET384E, MET384F, PHE348E, PHE348F, PRO261E, PRO261F, PRO299E, PRO299F, PRO342E, PRO342F, PRO356E, PRO356F, PRO359F, PRO366E, PRO366F, SER260E, SER260F, SER262E, SER262F, THR266E, THR267E, THR271E, THR271F, THR298E, THR298F, THR337E, THR343E, THR343F, TRP265E, TYR336E, TYR346E, TYR346F, TYR382E, TYR382F, TYR404F, VAL272E, VAL272F, VAL304F, VAL335E, VAL354E, VAL354F, VAL369E, VAL369F, VAL378E, VAL378F