3N1C

crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 134
  • Norm. En. per Res.: -3.6615
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.0162	-0.0162	6	0	0	14	0	0	0
A-C	-28.3531	-61.6401	-200.489	-290.4822	91	4	1	9200	3	15	15
A-D	-99.8015	23.6146	-360.003	-436.1899	129	25	12	14187	0	22	18
B-C	-114.926	-5.9658	-369.743	-490.6348	134	19	13	14071	2	26	21
B-D	-10.0055	-37.5211	-210.46	-257.9866	86	3	1	9052	2	14	14
C-D	0.0	0.0	-0.041	-0.041	6	0	0	21	0	0	1

Interface residues

• A-B: ALA99A, ALA99B, GLN21A, GLN21B, SER100A, SER100B
• A-C: ALA230A, ALA230C, ALA305A, ALA305C, ARG197C, ARG206A, ARG206C, ARG309A, ARG309C, ASP203A, ASP203C, ASP204A, ASP204C, ASP299A, ASP299C, CYS238A, CYS238C, GLN188A, GLN188C, GLN201A, GLN201C, GLN228A, GLN228C, GLN240A, GLN240C, GLN249A, GLN301A, GLN301C, GLU198A, GLU198C, GLY226A, GLY226C, GLY229A, GLY229C, ILE303A, ILE303C, LEU191A, LEU191C, LEU199A, LEU199C, LEU225A, LEU225C, LEU231A, LEU231C, LEU288A, LEU288C, LEU307A, LEU307C, LYS189C, LYS207A, LYS207C, LYS247A, LYS247C, LYS302A, LYS302C, PRO202A, PRO202C, PRO227A, PRO227C, PRO243A, PRO243C, PRO244A, PRO244C, PRO245A, PRO245C, SER192C, SER224A, SER224C, SER248A, SER248C, SER284A, SER284C, THR200A, THR200C, THR287A, TYR304A, TYR304C, TYR306A, TYR306C, VAL205A, VAL205C, VAL223A, VAL223C, VAL241A, VAL241C, VAL242A, VAL242C, VAL246A, VAL246C, VAL280A, VAL280C
• A-D: ALA10A, ALA10D, ALA16A, ALA16D, ALA32A, ALA32D, ALA64A, ALA64D, ARG105A, ARG105D, ARG29A, ARG29D, ARG90A, ARG90D, ASN43A, ASN43D, ASN92A, ASN92D, ASP166A, ASP166D, ASP256A, ASP256D, CYS30A, CYS30D, GLN103A, GLN103D, GLN21A, GLN21D, GLN249A, GLN249D, GLN91A, GLN91D, GLU102A, GLU102D, GLU25A, GLU25D, GLY101A, GLY101D, GLY110A, GLY110D, GLY138A, GLY138D, GLY169D, GLY253A, GLY253D, GLY255A, GLY255D, GLY26A, GLY26D, GLY291A, GLY291D, GLY39A, GLY39D, GLY40A, GLY40D, GLY63A, GLY63D, HIS68D, HIS94A, HIS94D, HIS96A, HIS96D, ILE18A, ILE18D, ILE22A, ILE22D, LEU13A, LEU140A, LEU140D, LEU28A, LEU28D, LEU93A, LEU93D, LYS189D, LYS27A, LYS27D, MET108A, MET108D, PHE106A, PHE106D, PHE35A, PHE35D, PRO109A, PRO109D, PRO142A, PRO142D, PRO24A, PRO24D, PRO33A, PRO33D, SER100A, SER100D, SER137A, SER137D, SER139A, SER139D, SER15A, SER15D, SER167A, SER167D, SER168A, SER168D, SER250A, SER250D, THR17A, THR17D, THR19A, THR19D, THR251A, THR251D, THR31A, THR31D, THR65A, THR65D, TRP88A, TRP88D, TYR104A, TYR104D, TYR23A, TYR23D, VAL107A, VAL107D, VAL252A, VAL252D, VAL34A, VAL95A, VAL95D, VAL97A, VAL97D
• B-C: ALA10B, ALA10C, ALA111B, ALA16B, ALA16C, ALA254C, ALA32B, ALA32C, ALA64B, ALA64C, ARG105B, ARG105C, ARG29B, ARG29C, ARG90B, ARG90C, ASN289C, ASN43B, ASN43C, ASN92B, ASN92C, ASP166B, ASP256B, ASP256C, ASP87B, CYS30B, CYS30C, GLN103B, GLN103C, GLN21B, GLN21C, GLN249B, GLN249C, GLN290C, GLN91B, GLN91C, GLU102B, GLU102C, GLU25B, GLU25C, GLU67B, GLU67C, GLY101B, GLY101C, GLY110B, GLY110C, GLY138B, GLY138C, GLY253B, GLY253C, GLY255B, GLY255C, GLY26B, GLY26C, GLY291C, GLY39B, GLY39C, GLY40B, GLY40C, GLY63B, GLY63C, HIS68B, HIS68C, HIS94B, HIS94C, HIS96B, HIS96C, ILE18B, ILE18C, ILE22B, ILE22C, LEU13B, LEU140B, LEU140C, LEU28B, LEU28C, LEU93B, LEU93C, LYS189B, LYS27B, LYS27C, MET108B, MET108C, PHE106B, PHE106C, PHE35B, PHE35C, PRO109B, PRO109C, PRO142B, PRO142C, PRO24B, PRO24C, PRO33B, PRO33C, SER100B, SER100C, SER137B, SER137C, SER139B, SER139C, SER15B, SER15C, SER167B, SER167C, SER168B, SER168C, SER248B, SER250B, SER250C, THR17B, THR17C, THR19B, THR19C, THR251C, THR287B, THR287C, THR31B, THR31C, THR65B, THR65C, TRP88B, TRP88C, TYR104B, TYR104C, TYR23B, TYR23C, VAL107B, VAL107C, VAL252C, VAL95B, VAL95C, VAL97B, VAL97C
• B-D: ALA230B, ALA230D, ALA305B, ALA305D, ARG206B, ARG206D, ARG309B, ARG309D, ASP203B, ASP203D, ASP204B, ASP204D, ASP299B, ASP299D, CYS238B, CYS238D, GLN188B, GLN188D, GLN201B, GLN201D, GLN228B, GLN228D, GLN240B, GLN240D, GLN301B, GLU198B, GLU198D, GLY226B, GLY226D, GLY229B, GLY229D, ILE303B, ILE303D, LEU191B, LEU191D, LEU199B, LEU199D, LEU225B, LEU225D, LEU231B, LEU231D, LEU288B, LEU288D, LEU307B, LEU307D, LYS207B, LYS207D, LYS247B, LYS247D, LYS302B, LYS302D, PRO202B, PRO202D, PRO227B, PRO227D, PRO243B, PRO243D, PRO244B, PRO244D, PRO245B, PRO245D, SER224B, SER224D, SER248B, SER248D, SER284B, SER284D, THR200B, THR200D, THR287B, TYR304B, TYR304D, TYR306B, TYR306D, VAL205B, VAL205D, VAL223B, VAL223D, VAL241B, VAL241D, VAL242B, VAL242D, VAL246B, VAL246D, VAL280B, VAL280D
• C-D: ALA99C, ALA99D, GLN21C, GLN21D, SER100C, SER100D