3MTU

structure of the tropomyosin overlap complex from chicken smooth muscle

• Total interactions analyzed: 15
• Total true interactions: 13
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 114
  • Norm. En. per Res.: -6.0456
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-84.5849	-150.0921	-454.525	-689.202	114	12	28	18858	9	63	74
A-C	-24.5501	22.096	-136.399	-138.8531	44	6	1	5089	4	19	14
A-D	0.0	0.0	-6.1208	-6.1208	14	0	1	505	0	4	1
A-E	-8.6348	0.0	-35.2122	-43.847	20	3	2	1744	0	3	0
A-F	-13.9579	-16.2647	-18.434	-48.6566	19	2	0	1049	1	4	1
B-C	0.0	0.0	-10.5084	-10.5084	21	0	0	684	0	4	17
B-D	-26.3595	-22.6488	-92.8395	-141.8478	38	3	0	3332	3	16	11
B-E	-6.012	-11.2033	-13.9783	-31.1935	22	1	0	751	1	6	3
B-F	-10.3769	0.0	-46.9609	-57.3378	22	2	3	2146	0	4	1
C-D	-90.9477	-118.6764	-457.091	-666.7151	113	12	29	19046	7	61	74
D-E	0.0	45.6434	-19.9131	25.7303	25	1	0	966	0	5	9
D-F	0.0	0.0	-0.924	-0.924	6	0	0	58	0	2	1
E-F	-49.1927	-69.3347	-370.379	-488.9064	105	19	21	14403	4	41	37

Interface residues

• A-B: ALA18A, ALA18B, ALA22A, ALA22B, ALA248A, ALA248B, ALA25A, ALA25B, ALA27A, ALA27B, ARG21A, ARG21B, ARG222A, ARG222B, ARG241A, ARG241B, ASN17A, ASN17B, ASN223A, ASN223B, ASN231A, ASN231B, ASP14A, ASP14B, ASP20A, ASP20B, ASP215A, ASP215B, ASP236A, ASP236B, ASP244A, ASP244B, ASP250A, ASP250B, ASP28A, ASP28B, CYS228A, CYS228B, GLN240A, GLN240B, GLN24A, GLN24B, GLN9A, GLN9B, GLU16A, GLU16B, GLU225A, GLU225B, GLU230A, GLU230B, GLU234A, GLU234B, GLU23A, GLU23B, GLU251A, GLU26A, GLU26B, GLY219A, GLY219B, GLY252A, ILE224A, ILE224B, ILE227A, ILE227B, ILE242A, ILE242B, ILE245A, ILE245B, ILE4A, ILE4B, LEU11A, LEU11B, LEU13A, LEU13B, LEU19A, LEU19B, LEU221A, LEU221B, LEU226A, LEU226B, LEU239A, LEU239B, LEU246A, LEU246B, LYS12A, LYS12B, LYS15A, LYS15B, LYS220A, LYS220B, LYS29A, LYS29B, LYS5A, LYS5B, LYS7A, LYS7B, PHE216A, PHE216B, PHE218A, PHE218B, PHE253A, PRO237A, PRO237B, THR249A, THR249B, TYR217A, TYR217B, TYR247A, TYR247B, VAL238A, VAL238B, VAL243A, VAL243B, VAL254A
• A-C: ALA248A, ALA3C, ARG222A, ARG241A, ASN231A, ASP14C, ASP244A, ASP250A, ASP257A, ASP2C, CYS228A, GLN229A, GLN240A, GLN9C, GLU16C, GLU225A, GLU230A, GLU232A, GLU251A, GLY233A, GLY252A, ILE245A, ILE255A, ILE4C, LEU11C, LEU13C, LEU19C, LEU221A, LEU226A, LEU239A, LEU246A, LYS12C, LYS15C, LYS5C, LYS6C, LYS7C, PHE218A, PHE253A, PRO256A, SER0C, THR249A, TYR247A, VAL243A, VAL254A
• A-D: ALA3D, ASP257A, GLU251A, ILE255A, ILE4D, LEU11A, LEU11D, LYS7D, PHE253A, PRO256A, SER0D, THR249A, THR249D, VAL254A
• A-E: ALA-1A, ALA3A, ASN282E, ASN283E, ASP275E, ASP2A, GLN9A, GLU280E, GLY-2A, HIS271E, ILE4A, LEU11A, LEU274E, LEU278E, LEU281E, LYS5A, LYS6A, LYS7A, SER0A, THR277E
• A-F: ALA3A, ASN282F, ASN283F, ASP2A, GLN276F, GLN9A, GLU280F, GLY-2A, ILE4A, LEU274F, LEU278F, LEU279F, LEU281F, LYS12A, LYS5A, LYS6A, LYS7A, SER0A, THR277F
• B-C: ASN17B, ASN17C, ASP20B, ASP20C, ASP28B, ASP28C, GLN24B, GLN24C, GLN9B, GLN9C, GLU16B, GLU16C, LEU13B, LEU13C, LYS12B, LYS220B, LYS220C, PHE216B, PHE216C, TYR217B, TYR217C
• B-D: ALA-1B, ALA248D, ALA3B, ARG222D, ARG241D, ASN231D, ASN235D, ASP236D, ASP244D, ASP250D, ASP2B, CYS228D, GLN229D, GLN240D, GLN9B, GLU16B, GLU225D, GLU232D, GLU234D, GLU251D, GLY-2B, GLY233D, ILE242D, ILE245D, ILE4B, LEU13B, LEU221D, LEU239D, LEU246D, LYS12B, LYS5B, LYS6B, LYS7B, PHE218D, SER0B, THR249D, TYR247D, VAL243D
• B-E: ASN269E, ASN282E, ASN283E, ASP275E, ASP2B, GLN272E, GLN276E, GLN9B, GLU16B, GLU266E, GLU280E, GLY-2B, ILE4B, LEU11B, LEU274E, LEU278E, LEU281E, LYS12B, LYS15B, LYS5B, LYS6B, THR277E
• B-F: ALA-1B, ALA3B, ASN282F, ASN283F, ASP275F, ASP2B, GLN272F, GLN276F, GLU280F, GLY-2B, HIS271F, ILE4B, LEU11B, LEU274F, LEU278F, LEU279F, LEU281F, LYS5B, LYS6B, LYS7B, SER0B, THR277F
• C-D: ALA18C, ALA18D, ALA22C, ALA22D, ALA248C, ALA248D, ALA25C, ALA25D, ALA27C, ALA27D, ARG21C, ARG21D, ARG222C, ARG222D, ARG241C, ARG241D, ASN17C, ASN17D, ASN223C, ASN223D, ASN231C, ASN231D, ASP14C, ASP14D, ASP20C, ASP20D, ASP215C, ASP215D, ASP236C, ASP236D, ASP244C, ASP244D, ASP250C, ASP250D, ASP28C, ASP28D, CYS228C, CYS228D, GLN240C, GLN240D, GLN24C, GLN24D, GLN9C, GLN9D, GLU16C, GLU16D, GLU225C, GLU225D, GLU230C, GLU230D, GLU232C, GLU234C, GLU234D, GLU23C, GLU23D, GLU251D, GLU26C, GLU26D, GLY219C, GLY219D, ILE224C, ILE224D, ILE227C, ILE227D, ILE242C, ILE242D, ILE245C, ILE245D, ILE4C, ILE4D, LEU11C, LEU11D, LEU13C, LEU13D, LEU19C, LEU19D, LEU221C, LEU221D, LEU226C, LEU226D, LEU239C, LEU239D, LEU246C, LEU246D, LYS12C, LYS12D, LYS15C, LYS15D, LYS220C, LYS220D, LYS29C, LYS29D, LYS5C, LYS5D, LYS7C, LYS7D, PHE216C, PHE216D, PHE218C, PHE218D, PRO237C, PRO237D, SER0D, THR249C, THR249D, TYR217C, TYR217D, TYR247C, TYR247D, VAL238C, VAL238D, VAL243C, VAL243D
• D-E: ALA248D, ARG241D, ASN235D, ASN269E, ASN283E, ASP236D, ASP244D, ASP250D, GLN240D, GLN272E, GLN276E, GLU234D, GLU251D, GLU265E, GLU266E, GLU280E, GLY233D, HIS262E, ILE245D, LEU281E, PRO237D, THR249D, THR277E, TYR247D, VAL243D
• D-F: ASN235D, ASN267F, GLN240D, GLU232D, GLY233D, HIS271F
• E-F: ALA261E, ALA261F, ALA263E, ALA263F, ALA28E, ALA28F, ARG25E, ARG25F, ARG33E, ARG33F, ASN13E, ASN13F, ASN267E, ASN267F, ASN269F, ASN35E, ASN35F, ASN44E, ASN44F, ASP10E, ASP17E, ASP17F, ASP45E, ASP45F, GLN22E, GLN22F, GLN30E, GLN30F, GLN31E, GLN31F, GLU257E, GLU257F, GLU258E, GLU258F, GLU265E, GLU265F, GLU266E, GLU266F, GLU27E, GLU27F, GLU42E, GLU42F, GLU6E, GLU6F, GLU7E, GLU7F, GLU9E, GLU9F, GLY37E, GLY37F, HIS262E, HIS262F, HIS271E, HIS271F, HIS8E, HIS8F, ILE11E, ILE11F, LEU12E, LEU12F, LEU15E, LEU15F, LEU16E, LEU16F, LEU256E, LEU256F, LEU268F, LEU274E, LEU274F, LEU278E, LEU29E, LEU29F, LEU32E, LEU32F, LYS14E, LYS14F, LYS259E, LYS259F, LYS264E, LYS264F, PHE39E, PHE39F, PRO18E, PRO18F, PRO5E, PRO5F, SER23F, SER38E, SER38F, SER41E, SER41F, THR26E, THR26F, THR277E, THR277F, TYR36E, TYR36F, TYR43E, TYR43F, VAL260E, VAL260F, VAL34E, VAL34F, VAL40E, VAL40F