3MQ9

crystal structure of ectodomain mutant of bst-2/tetherin/cd317 fused to mbp

• Total interactions analyzed: 28
• Total true interactions: 19
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 87
  • Norm. En. per Res.: -2.9861
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.9364	49.6189	-445.071	-425.3884	221	25	14	18590	5	44	51
A-C	-2.5501	33.0278	-292.8	-262.3223	149	18	18	13565	3	58	47
A-D	-3.0538	-42.5694	-269.485	-315.1082	145	19	35	13928	3	38	47
A-F	0.0	0.0	-11.234	-11.234	11	0	0	423	0	5	7
B-C	-3.7135	-31.0892	-270.122	-304.9248	146	14	35	13855	3	38	53
B-D	-11.3826	17.177	-280.456	-274.6616	166	20	19	12904	3	62	49
B-G	0.0	0.0	-1.3149	-1.3149	11	0	1	127	0	5	6
C-D	-13.0482	-53.3239	-193.417	-259.7891	87	18	11	8877	1	17	16
C-F	0.0	0.0	-1.2326	-1.2326	14	0	0	222	0	6	4
C-H	0.0	-6.8242	-2.6671	-9.4913	12	0	1	362	0	11	12
D-F	0.0	2.3744	-19.812	-17.4376	34	3	0	1443	0	27	23
D-G	0.0	-4.3789	-7.9937	-12.3726	24	0	0	575	1	10	7
D-H	0.0	0.0	-1.263	-1.263	17	2	0	362	0	9	9
E-F	-25.933	47.46	-429.18	-407.653	218	26	13	18320	6	44	50
E-G	-5.7415	26.2814	-263.778	-243.2381	144	17	18	12287	3	58	43
E-H	0.0	-37.1322	-241.744	-278.8762	146	20	35	13626	3	36	47
F-G	0.0	-30.9305	-233.762	-264.6925	141	20	35	13488	3	36	49
F-H	-11.1988	-25.9401	-286.751	-323.8899	167	23	19	13504	3	70	49
G-H	0.0	-34.5463	-187.228	-221.7742	76	23	10	8252	1	15	16

Interface residues

• A-B: ALA213B, ALA215A, ALA215B, ALA216A, ALA216B, ALA231A, ALA231B, ALA338A, ALA338B, ALA342A, ALA342B, ALA370A, ALA370B, ALA371A, ALA371B, ALA377A, ALA377B, ALA381A, ALA381B, ALA395A, ALA395B, ALA404A, ALA404B, ALA406A, ALA406B, ALA407A, ALA407B, ALA409A, ALA409B, ALA415A, ALA415B, ALA418A, ALA418B, ALA422A, ALA422B, ALA425A, ALA425B, ALA63A, ALA63B, ARG344A, ARG344B, ARG372A, ARG372B, ARG376A, ARG376B, ARG382A, ARG382B, ARG66A, ARG66B, ASN12A, ASN12B, ASN150A, ASN150B, ASN218A, ASN218B, ASN227A, ASN227B, ASN234A, ASN234B, ASN332A, ASN332B, ASN383A, ASN383B, ASN410A, ASN410B, ASP14A, ASP14B, ASP209B, ASP236A, ASP236B, ASP373A, ASP373B, ASP401A, ASP401B, ASP421A, ASP421B, ASP65A, ASP65B, GLN152A, GLN152B, GLN335A, GLN335B, GLN389A, GLN389B, GLN390A, GLN390B, GLN396A, GLN396B, GLN400A, GLN400B, GLN405A, GLN405B, GLN426A, GLN426B, GLN428A, GLN428B, GLU111A, GLU111B, GLU153A, GLU153B, GLU214A, GLU214B, GLU380A, GLU380B, GLU391A, GLU391B, GLU394A, GLU394B, GLU403A, GLU403B, GLU423A, GLU423B, GLU432A, GLU432B, GLU44A, GLU44B, GLU45A, GLU45B, GLY228A, GLY228B, GLY374A, GLY374B, GLY398A, GLY398B, GLY427A, GLY427B, HIS386A, HIS386B, HIS411A, HIS411B, ILE212A, ILE212B, ILE235A, ILE235B, LEU375A, LEU375B, LEU387A, LEU387B, LEU388A, LEU388B, LEU392A, LEU392B, LEU416A, LEU416B, LEU420A, LEU420B, LYS15A, LYS15B, LYS239A, LYS239B, LYS297A, LYS297B, LYS397A, LYS397B, LYS424A, LYS424B, LYS429A, LYS429B, LYS42A, LYS42B, LYS430A, LYS430B, MET330A, MET330B, MET336A, MET336B, PHE156A, PHE156B, PHE339A, PHE339B, PHE399A, PHE399B, PRO154A, PRO154B, PRO229A, PRO229B, PRO331B, PRO334A, PRO334B, SER211A, SER211B, SER233A, SER233B, SER238A, SER238B, SER337A, SER337B, SER419A, SER419B, THR237A, THR237B, THR385A, THR385B, THR393A, THR393B, THR408A, THR408B, THR412A, THR412B, TRP230A, TRP230B, TRP232A, TRP232B, TRP340A, TRP340B, TRP62A, TRP62B, TYR155A, TYR155B, TYR210A, TYR210B, TYR341A, TYR341B, VAL378A, VAL378B, VAL384A, VAL384B, VAL402A, VAL402B, VAL413A, VAL413B
• A-C: ALA338A, ALA342A, ALA346A, ALA364A, ALA370A, ALA370C, ALA371A, ALA371C, ALA377A, ALA377C, ALA381A, ALA381C, ALA395A, ALA395C, ALA404C, ALA406C, ALA407C, ALA409C, ALA415C, ALA418C, ALA422C, ALA51C, ALA52C, ARG344A, ARG354A, ARG367A, ARG372A, ARG372C, ARG376A, ARG376C, ARG382A, ARG382C, ARG66C, ASN100A, ASN150A, ASN234A, ASN349A, ASN383A, ASN383C, ASN410C, ASP177A, ASP180A, ASP209A, ASP363A, ASP373A, ASP373C, ASP401A, ASP401C, ASP55C, GLN152A, GLN389A, GLN389C, GLN390A, GLN390C, GLN396A, GLN396C, GLN400A, GLN400C, GLN405A, GLN405C, GLN49C, GLU153A, GLU172A, GLU380A, GLU380C, GLU38C, GLU391A, GLU391C, GLU394A, GLU394C, GLU403C, GLU423C, GLU45C, GLU4C, GLY374A, GLY374C, GLY398A, GLY398C, GLY54C, GLY56C, GLY5C, HIS386A, HIS386C, HIS411C, ILE178A, ILE212A, ILE348A, ILE368A, LEU375A, LEU375C, LEU387A, LEU387C, LEU388A, LEU388C, LEU392A, LEU392C, LEU416C, LEU420C, LEU43C, LYS170A, LYS175A, LYS179A, LYS34C, LYS397A, LYS397C, LYS42C, LYS46C, LYS6C, PHE156A, PHE339A, PHE399A, PHE399C, PHE47C, PRO154A, PRO48C, PRO57C, SER211A, SER337A, SER419C, SER73C, THR345A, THR366A, THR366C, THR369A, THR369C, THR36C, THR385A, THR385C, THR393A, THR393C, THR408C, THR412C, THR53C, TRP10C, TRP340A, TYR176A, TYR210A, TYR341A, VAL343A, VAL347A, VAL378A, VAL378C, VAL384A, VAL384C, VAL402A, VAL402C, VAL413C, VAL50C, VAL8C
• A-D: ALA269D, ALA377A, ALA377D, ALA381A, ALA381D, ALA395A, ALA395D, ALA406A, ALA406D, ALA409A, ALA409D, ALA415A, ALA415D, ALA418A, ALA418D, ALA422A, ALA422D, ALA425A, ALA425D, ALA448A, ALA448D, ALA450A, ALA450D, ALA52A, ALA52D, ARG454A, ARG454D, ARG456A, ARG456D, ARG457A, ARG457D, ASN410A, ASN410D, ASN442A, ASN442D, ASP401A, ASP401D, ASP421A, ASP421D, ASP447A, ASP447D, GLN389A, GLN389D, GLN396A, GLN396D, GLN400A, GLN400D, GLN405A, GLN405D, GLN426A, GLN426D, GLN428A, GLN428D, GLN446A, GLN446D, GLU391A, GLU391D, GLU394A, GLU394D, GLU403A, GLU403D, GLU423A, GLU423D, GLU432A, GLU432D, GLU433A, GLU433D, GLU435A, GLU435D, GLU437A, GLU437D, GLU451A, GLU451D, GLU453A, GLU453D, GLY374A, GLY374D, GLY398A, GLY398D, GLY427A, GLY427D, GLY436A, GLY436D, GLY54D, HIS411A, HIS411D, HIS443A, HIS443D, ILE438A, ILE438D, LEU388A, LEU388D, LEU392A, LEU392D, LEU416A, LEU416D, LEU420A, LEU420D, LEU434A, LEU434D, LEU441A, LEU441D, LEU445A, LEU445D, LEU455A, LEU455D, LYS397A, LYS397D, LYS424A, LYS424D, LYS429D, LYS430A, LYS430D, LYS444A, LYS444D, PHE399A, PHE399D, SER419A, SER419D, SER449A, SER449D, THR385A, THR385D, THR393A, THR408A, THR408D, THR412A, THR412D, THR439A, THR439D, THR440A, THR440D, THR53A, THR53D, VAL378A, VAL378D, VAL384A, VAL402A, VAL402D, VAL413A, VAL413D, VAL431A, VAL431D, VAL452A, VAL452D
• A-F: ARG354A, ASN349A, GLN253F, GLN355A, GLY252F, ILE348A, LYS251F, PHE250F, PRO254F, SER352A, THR249F
• B-C: ALA371C, ALA377B, ALA377C, ALA381B, ALA381C, ALA395B, ALA395C, ALA406B, ALA406C, ALA409B, ALA409C, ALA415B, ALA415C, ALA418B, ALA418C, ALA422B, ALA422C, ALA425B, ALA425C, ALA448B, ALA448C, ALA450B, ALA450C, ARG354B, ARG354C, ARG454B, ARG456B, ARG456C, ARG457B, ARG457C, ASN410B, ASN410C, ASN442B, ASN442C, ASP401B, ASP401C, ASP421B, ASP421C, ASP447B, ASP447C, GLN355C, GLN389B, GLN389C, GLN396B, GLN396C, GLN400B, GLN400C, GLN405B, GLN405C, GLN426B, GLN426C, GLN428B, GLN428C, GLN446B, GLN446C, GLU391B, GLU391C, GLU394B, GLU394C, GLU403B, GLU403C, GLU423B, GLU423C, GLU432B, GLU432C, GLU433B, GLU433C, GLU435B, GLU435C, GLU437B, GLU437C, GLU451B, GLU451C, GLU453B, GLU453C, GLY353C, GLY374B, GLY374C, GLY398B, GLY398C, GLY427B, GLY427C, GLY436B, GLY436C, HIS411B, HIS411C, HIS443B, HIS443C, ILE438B, ILE438C, LEU375B, LEU388B, LEU388C, LEU392B, LEU392C, LEU416B, LEU416C, LEU420B, LEU420C, LEU434B, LEU434C, LEU441B, LEU441C, LEU445B, LEU445C, LEU455B, LEU455C, LYS397B, LYS397C, LYS424B, LYS424C, LYS429B, LYS429C, LYS430B, LYS430C, LYS444B, LYS444C, PHE399B, PHE399C, SER419B, SER419C, SER449B, SER449C, THR385B, THR385C, THR408B, THR408C, THR412B, THR412C, THR439B, THR439C, THR440B, THR440C, TYR341B, VAL378B, VAL378C, VAL384B, VAL384C, VAL402B, VAL402C, VAL413B, VAL413C, VAL431B, VAL431C, VAL452B, VAL452C
• B-D: ALA141D, ALA206D, ALA215D, ALA216D, ALA338B, ALA338D, ALA342B, ALA342D, ALA346B, ALA364B, ALA370B, ALA371B, ALA371D, ALA377B, ALA377D, ALA381B, ALA381D, ALA395B, ALA395D, ALA404D, ALA406D, ALA407D, ALA409D, ALA415D, ALA71B, ARG344B, ARG344D, ARG354B, ARG354D, ARG367B, ARG367D, ARG372B, ARG372D, ARG376B, ARG376D, ARG382B, ARG382D, ARG66D, ASN100B, ASN150B, ASN173B, ASN205D, ASN218D, ASN234B, ASN349B, ASN383B, ASN383D, ASN410D, ASP177B, ASP180B, ASP207D, ASP209B, ASP363B, ASP373B, ASP373D, ASP401B, ASP401D, GLN152B, GLN152D, GLN389B, GLN389D, GLN390B, GLN390D, GLN396B, GLN396D, GLN400D, GLN405B, GLN405D, GLN72B, GLN72D, GLU153B, GLU153D, GLU172B, GLU221D, GLU380B, GLU380D, GLU391B, GLU391D, GLU394B, GLU394D, GLU403D, GLU423D, GLU45D, GLU78B, GLY101B, GLY143D, GLY174B, GLY220D, GLY374B, GLY374D, GLY398B, GLY398D, GLY74B, HIS386B, HIS386D, HIS411D, ILE178B, ILE212B, ILE212D, ILE348B, ILE348D, ILE368B, LEU121D, LEU139D, LEU375B, LEU375D, LEU387B, LEU387D, LEU388B, LEU388D, LEU392B, LEU392D, LEU416D, LEU420D, LYS102B, LYS140D, LYS142D, LYS144D, LYS175B, LYS179B, LYS202D, LYS219D, LYS397B, LYS397D, MET148D, PHE156B, PHE339B, PHE399B, PHE399D, PRO154B, PRO334D, SER145D, SER211B, SER337B, SER337D, SER352D, SER419D, SER73B, SER73D, THR222D, THR345B, THR345D, THR366B, THR369B, THR385B, THR385D, THR393B, THR393D, THR408D, THR412D, TRP340B, TRP340D, TYR210B, TYR341B, TYR341D, TYR99B, VAL240D, VAL343B, VAL347B, VAL378B, VAL378D, VAL384B, VAL384D, VAL402B, VAL402D, VAL413D
• B-G: ALA141G, ALA186B, ASN185B, GLY143G, GLY165B, GLY187B, LYS140G, LYS142G, LYS189B, LYS202G, LYS362B
• C-D: ALA338C, ALA342C, ALA360C, ALA370C, ALA371C, ALA377C, ALA377D, ALA381C, ALA381D, ALA395C, ALA395D, ALA404C, ALA404D, ALA406D, ALA407D, ALA415D, ALA418D, ARG344C, ARG354C, ARG367C, ARG372C, ARG372D, ARG376C, ARG376D, ARG382C, ARG382D, ASN349C, ASN383C, ASN383D, ASN410D, ASP363C, ASP373C, ASP373D, ASP401C, ASP401D, GLN355C, GLN389C, GLN389D, GLN390C, GLN390D, GLN396C, GLN396D, GLN400C, GLN400D, GLU359C, GLU380C, GLU380D, GLU391C, GLU391D, GLU394C, GLU394D, GLU403C, GLU403D, GLY374C, GLY374D, GLY398C, GLY398D, HIS386C, HIS386D, HIS411D, LEU375C, LEU375D, LEU387C, LEU387D, LEU388C, LEU388D, LEU392C, LEU392D, LYS362C, LYS397C, LYS397D, PHE399C, PHE399D, THR345C, THR356C, THR366C, THR385C, THR385D, THR393C, THR393D, THR408D, TYR341C, VAL378C, VAL378D, VAL384C, VAL384D, VAL402D
• C-F: ALA186F, ALA190F, ALA404C, ALA407C, ASP164F, ASP401C, GLN253F, GLN396C, GLN400C, GLU403C, HIS411C, LYS251F, PHE250F, THR193F
• C-H: ALA134H, ALA141H, ALA422C, ALA425C, ASP421C, GLN426C, GLN428C, GLU138H, GLU432C, LYS137H, LYS142H, LYS429C
• D-F: ALA186F, ALA360F, ALA370D, ALA371D, ARG354F, ARG367D, ARG367F, ARG372D, ARG376D, ASN349F, ASN383D, ASP184F, ASP358F, ASP363D, ASP363F, GLN355F, GLN365D, GLN365F, GLU359D, GLU359F, GLU380D, HIS386D, LEU375D, LYS179D, LYS189F, LYS200F, LYS362D, LYS362F, THR356F, THR366D, THR366F, THR369D, VAL181D, VAL357F
• D-G: ALA186D, ALA215G, ARG354G, ARG382G, ASN201D, ASN205G, ASP197D, ASP207G, ASP209G, ASP358D, GLN152G, GLN355D, GLU221G, GLU359D, ILE212G, ILE348G, LYS137D, LYS200D, LYS202D, LYS219G, SER211G, SER352G, THR356D, VAL196D
• D-H: ALA186D, ARG354H, ASN173D, ASN185D, ASP184D, ASP358H, GLN355H, GLN390H, GLU172D, GLU359H, GLY353H, LYS170D, LYS189D, LYS397H, THR356H, THR393H, VAL357H
• E-F: ALA213F, ALA215E, ALA215F, ALA216F, ALA231E, ALA231F, ALA338E, ALA338F, ALA342E, ALA342F, ALA370E, ALA370F, ALA371E, ALA371F, ALA377E, ALA377F, ALA381E, ALA381F, ALA395E, ALA395F, ALA404E, ALA404F, ALA406E, ALA406F, ALA407E, ALA407F, ALA409E, ALA409F, ALA415E, ALA415F, ALA418E, ALA418F, ALA422E, ALA422F, ALA425E, ALA425F, ALA63E, ALA63F, ARG344E, ARG344F, ARG372E, ARG372F, ARG376E, ARG376F, ARG382E, ARG382F, ARG66E, ARG66F, ASN12E, ASN12F, ASN150E, ASN150F, ASN218E, ASN218F, ASN227E, ASN227F, ASN234E, ASN234F, ASN332E, ASN332F, ASN383E, ASN383F, ASN410E, ASN410F, ASP14E, ASP14F, ASP209F, ASP236E, ASP236F, ASP373E, ASP373F, ASP401E, ASP401F, ASP421E, ASP421F, ASP65E, ASP65F, GLN152E, GLN152F, GLN335E, GLN335F, GLN389E, GLN389F, GLN390E, GLN390F, GLN396E, GLN396F, GLN400E, GLN400F, GLN405E, GLN405F, GLN426E, GLN426F, GLN428E, GLN428F, GLU111E, GLU111F, GLU153E, GLU153F, GLU214E, GLU214F, GLU380E, GLU380F, GLU391E, GLU391F, GLU394E, GLU394F, GLU403E, GLU403F, GLU423E, GLU423F, GLU432E, GLU432F, GLU44E, GLU44F, GLU45E, GLU45F, GLY228E, GLY228F, GLY374E, GLY374F, GLY398E, GLY398F, GLY427E, GLY427F, HIS386E, HIS386F, HIS411E, HIS411F, ILE212E, ILE212F, ILE235E, ILE235F, LEU375E, LEU375F, LEU387E, LEU387F, LEU388E, LEU388F, LEU392E, LEU392F, LEU416E, LEU416F, LEU420E, LEU420F, LYS15E, LYS239E, LYS239F, LYS297E, LYS297F, LYS397E, LYS397F, LYS424E, LYS424F, LYS429E, LYS429F, LYS42E, LYS42F, LYS430E, MET330E, MET330F, MET336E, MET336F, PHE156E, PHE156F, PHE339E, PHE339F, PHE399E, PHE399F, PRO154E, PRO154F, PRO229E, PRO229F, PRO331E, PRO334E, PRO334F, SER211E, SER211F, SER233E, SER233F, SER238E, SER238F, SER337E, SER337F, SER419E, SER419F, THR237E, THR237F, THR385E, THR385F, THR393E, THR393F, THR408E, THR408F, THR412E, THR412F, TRP230E, TRP230F, TRP232E, TRP232F, TRP340E, TRP340F, TRP62E, TRP62F, TYR155E, TYR155F, TYR210E, TYR210F, TYR341E, TYR341F, VAL378E, VAL378F, VAL384E, VAL384F, VAL402E, VAL402F, VAL413E, VAL413F
• E-G: ALA338E, ALA342E, ALA346E, ALA364E, ALA370E, ALA370G, ALA371E, ALA371G, ALA377E, ALA377G, ALA381E, ALA381G, ALA395E, ALA395G, ALA404G, ALA406G, ALA407G, ALA409G, ALA415G, ALA51G, ALA52G, ARG344E, ARG354E, ARG367E, ARG372E, ARG372G, ARG376E, ARG376G, ARG382E, ARG382G, ARG66G, ASN100E, ASN150E, ASN234E, ASN349E, ASN383E, ASN383G, ASN410G, ASP177E, ASP180E, ASP209E, ASP363E, ASP373E, ASP373G, ASP401E, ASP401G, ASP55G, GLN152E, GLN389E, GLN389G, GLN390E, GLN390G, GLN396E, GLN396G, GLN400G, GLN405E, GLN405G, GLN49G, GLU153E, GLU172E, GLU380E, GLU380G, GLU38G, GLU391E, GLU391G, GLU394E, GLU394G, GLU403G, GLU423G, GLU45G, GLU4G, GLY374E, GLY374G, GLY398E, GLY398G, GLY54G, GLY56G, GLY5G, HIS386E, HIS386G, HIS411G, ILE178E, ILE212E, ILE348E, ILE368E, LEU375E, LEU375G, LEU387E, LEU387G, LEU388E, LEU388G, LEU392E, LEU392G, LEU416G, LEU420G, LYS170E, LYS175E, LYS179E, LYS34G, LYS397E, LYS397G, LYS42G, LYS46G, LYS6G, PHE156E, PHE339E, PHE399E, PHE399G, PHE47G, PRO154E, PRO40G, PRO48G, PRO57G, SER211E, SER337E, SER419G, SER73G, THR345E, THR366E, THR369E, THR36G, THR385E, THR385G, THR393E, THR393G, THR408G, THR412G, THR53G, TRP10G, TRP340E, TYR176E, TYR210E, TYR341E, VAL343E, VAL347E, VAL378E, VAL378G, VAL384E, VAL384G, VAL402E, VAL402G, VAL413G, VAL50G, VAL8G
• E-H: ALA269H, ALA377E, ALA377H, ALA381E, ALA381H, ALA395E, ALA395H, ALA406E, ALA406H, ALA409E, ALA409H, ALA415E, ALA415H, ALA418E, ALA418H, ALA422E, ALA422H, ALA425E, ALA425H, ALA448E, ALA448H, ALA450E, ALA450H, ALA51H, ALA52E, ALA52H, ARG454E, ARG456E, ARG456H, ARG457E, ARG457H, ASN410E, ASN410H, ASN442E, ASN442H, ASP401E, ASP401H, ASP421E, ASP421H, ASP447E, ASP447H, ASP55H, GLN389E, GLN389H, GLN396E, GLN396H, GLN400E, GLN400H, GLN405E, GLN405H, GLN426E, GLN426H, GLN428E, GLN428H, GLN446E, GLN446H, GLU391E, GLU391H, GLU394E, GLU394H, GLU403E, GLU403H, GLU423E, GLU423H, GLU432E, GLU432H, GLU433E, GLU433H, GLU435E, GLU435H, GLU437E, GLU437H, GLU451E, GLU451H, GLU453E, GLU453H, GLY374E, GLY374H, GLY398E, GLY398H, GLY427E, GLY427H, GLY436E, GLY436H, GLY54H, HIS411E, HIS411H, HIS443E, HIS443H, ILE438E, ILE438H, LEU388E, LEU388H, LEU392E, LEU392H, LEU416E, LEU416H, LEU420E, LEU420H, LEU434E, LEU434H, LEU441E, LEU441H, LEU445E, LEU445H, LEU455E, LEU455H, LYS397E, LYS397H, LYS424E, LYS424H, LYS429H, LYS430E, LYS430H, LYS444E, LYS444H, PHE399E, PHE399H, SER419E, SER419H, SER449E, SER449H, THR385E, THR385H, THR408E, THR408H, THR412E, THR412H, THR439E, THR439H, THR440E, THR440H, THR53E, THR53H, VAL378E, VAL378H, VAL384E, VAL384H, VAL402E, VAL402H, VAL413E, VAL413H, VAL431E, VAL431H, VAL452E, VAL452H
• F-G: ALA377F, ALA377G, ALA381F, ALA381G, ALA395F, ALA395G, ALA406F, ALA406G, ALA409F, ALA409G, ALA415F, ALA415G, ALA418F, ALA418G, ALA422F, ALA422G, ALA425F, ALA425G, ALA448F, ALA448G, ALA450F, ALA450G, ARG354F, ARG354G, ARG454F, ARG456F, ARG456G, ARG457F, ARG457G, ASN410F, ASN410G, ASN442F, ASN442G, ASP401F, ASP401G, ASP421F, ASP421G, ASP447F, ASP447G, GLN355G, GLN389F, GLN389G, GLN396F, GLN396G, GLN400F, GLN400G, GLN405F, GLN405G, GLN426F, GLN426G, GLN428F, GLN428G, GLN446F, GLN446G, GLU391F, GLU391G, GLU394F, GLU394G, GLU403F, GLU403G, GLU423F, GLU423G, GLU432F, GLU432G, GLU433F, GLU433G, GLU435F, GLU435G, GLU437F, GLU437G, GLU451F, GLU451G, GLU453F, GLU453G, GLY374F, GLY374G, GLY398F, GLY398G, GLY427F, GLY427G, GLY436F, GLY436G, HIS411F, HIS411G, HIS443F, HIS443G, ILE438F, ILE438G, LEU375F, LEU388F, LEU388G, LEU392F, LEU392G, LEU416F, LEU416G, LEU420F, LEU420G, LEU434F, LEU434G, LEU441F, LEU441G, LEU445F, LEU445G, LEU455F, LEU455G, LYS397F, LYS397G, LYS424F, LYS424G, LYS429G, LYS430F, LYS430G, LYS444F, LYS444G, PHE399F, PHE399G, SER419F, SER419G, SER449F, SER449G, THR385F, THR385G, THR408F, THR408G, THR412F, THR412G, THR439F, THR439G, THR440F, THR440G, VAL378F, VAL378G, VAL384F, VAL402F, VAL402G, VAL413F, VAL413G, VAL431F, VAL431G, VAL452F, VAL452G
• F-H: ALA141H, ALA206H, ALA215H, ALA216H, ALA338F, ALA338H, ALA342F, ALA342H, ALA346F, ALA364F, ALA370F, ALA371F, ALA371H, ALA377F, ALA377H, ALA381F, ALA381H, ALA395F, ALA395H, ALA404H, ALA406H, ALA407H, ALA409H, ALA415H, ALA418H, ALA422H, ALA71F, ARG344F, ARG344H, ARG354F, ARG354H, ARG367F, ARG367H, ARG372F, ARG372H, ARG376F, ARG376H, ARG382F, ARG382H, ARG66H, ASN100F, ASN150F, ASN173F, ASN205H, ASN218H, ASN234F, ASN349F, ASN383F, ASN383H, ASN410H, ASP177F, ASP180F, ASP207H, ASP209F, ASP209H, ASP363F, ASP373F, ASP373H, ASP401F, ASP401H, GLN152F, GLN152H, GLN335H, GLN389F, GLN389H, GLN390F, GLN390H, GLN396F, GLN396H, GLN400H, GLN405H, GLN72F, GLN72H, GLU153F, GLU153H, GLU172F, GLU214F, GLU221H, GLU380F, GLU380H, GLU391F, GLU391H, GLU394F, GLU394H, GLU403H, GLU423H, GLU45H, GLY101F, GLY143H, GLY174F, GLY220H, GLY374F, GLY374H, GLY398F, GLY398H, GLY74F, HIS386F, HIS386H, HIS411H, ILE178F, ILE212F, ILE212H, ILE348F, ILE348H, ILE368F, LEU139H, LEU375F, LEU375H, LEU387F, LEU387H, LEU388F, LEU388H, LEU392F, LEU392H, LEU416H, LEU420H, LYS102F, LYS140H, LYS142H, LYS144H, LYS175F, LYS179F, LYS202H, LYS219H, LYS397F, LYS397H, MET148H, PHE156F, PHE339F, PHE399F, PHE399H, PRO154F, PRO334H, SER145H, SER211F, SER337F, SER337H, SER352H, SER419H, SER73F, THR222H, THR345F, THR345H, THR366F, THR369F, THR385F, THR385H, THR393F, THR393H, THR408H, THR412H, TRP340F, TRP340H, TYR210F, TYR341F, TYR341H, TYR99F, VAL240H, VAL343F, VAL347F, VAL378F, VAL378H, VAL384F, VAL384H, VAL402F, VAL402H, VAL413H
• G-H: ALA377G, ALA377H, ALA381G, ALA381H, ALA395G, ALA395H, ALA404G, ALA404H, ALA407H, ALA415H, ALA418H, ARG344G, ARG367G, ARG372G, ARG376G, ARG376H, ARG382G, ARG382H, ASN383G, ASN383H, ASN410H, ASP363G, ASP373G, ASP373H, ASP401G, ASP401H, GLN355G, GLN389G, GLN389H, GLN390G, GLN390H, GLN396G, GLN396H, GLN400G, GLN400H, GLU359G, GLU380G, GLU380H, GLU391G, GLU391H, GLU394G, GLU394H, GLU403G, GLU403H, GLY374G, GLY374H, GLY398G, GLY398H, HIS386G, HIS386H, HIS411H, LEU375G, LEU375H, LEU387G, LEU387H, LEU388G, LEU388H, LEU392G, LEU392H, LYS362G, LYS397G, LYS397H, PHE399G, PHE399H, THR366G, THR385G, THR385H, THR393G, THR393H, TYR341G, VAL378G, VAL378H, VAL384G, VAL384H, VAL402G, VAL402H