3MO5

human g9a-like (glp, also known as ehmt1) in complex with inhibitor e72

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 109
  • Norm. En. per Res.: -3.644
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-97.0627	8.05	-308.188	-397.2006	109	17	4	11251	0	27	24
A-C	-5.5266	-16.1338	-25.856	-47.5165	32	1	0	1325	3	16	10
B-C	-16.5926	-18.0713	-73.8685	-108.5323	52	4	0	3615	2	37	34
B-D	-7.0945	-24.2965	-13.2353	-44.6264	18	1	0	642	1	14	9
C-D	-88.5297	5.8188	-306.29	-389.0008	110	10	3	10976	0	25	24

Interface residues

• A-B: ALA1077A, ALA1077B, ALA1184A, ALA1184B, ALA984A, ALA984B, ARG1023A, ARG1023B, ARG1082A, ARG1082B, ARG1087A, ARG1087B, ARG981A, ARG981B, ARG985A, ARG985B, ARG989B, ASN1013A, ASN1013B, ASN1020A, ASN1020B, ASN1024A, ASN1024B, ASN1075A, ASN1075B, ASN1083A, ASN1083B, ASP1022A, ASP1022B, ASP982A, ASP982B, CYS1014A, CYS1014B, CYS1031A, CYS1031B, CYS1033B, CYS1074A, CYS1074B, CYS1078A, CYS1078B, CYS1080A, CYS1080B, CYS1084A, CYS1084B, GLN1012A, GLN1012B, GLN1090A, GLN1090B, GLU1127A, GLU1127B, GLU988A, GLU988B, GLY986A, GLY986B, HIS1027A, HIS1027B, HIS1076A, HIS1076B, ILE1021A, ILE1021B, ILE1025A, ILE1025B, ILE1034B, ILE983A, ILE983B, ILE992A, ILE992B, LEU1028A, LEU1028B, LYS1008A, LYS1008B, MET1019A, MET1019B, PHE1160A, PHE1160B, PRO1018A, PRO1018B, PRO991A, PRO991B, PRO993A, PRO993B, SER1011A, SER1011B, SER1017A, SER1017B, SER1079A, SER1079B, SER980A, SER980B, THR1016A, THR1016B, THR1026A, THR1026B, TRP1081A, TRP1081B, TYR1009A, TYR1009B, TYR1030A, TYR1030B, TYR1161A, TYR1161B, TYR987A, TYR987B, VAL1010A, VAL1010B, VAL1015A, VAL1015B, VAL1032A, VAL1032B
• A-C: ALA1203C, ARG1058C, ARG1096A, ARG1199C, ARG981A, ARG989A, ASP1054C, ASP1114C, ASP982A, GLN1098A, GLN1113A, GLN1113C, GLU1062C, GLU1202C, GLU1205C, GLY1118C, GLY1204C, ILE1115C, ILE1201C, ILE978A, ILE990A, ILE992A, LEU1059C, LEU1060C, LEU1112A, LEU1200C, PRO1061C, PRO1116C, PRO1117C, PRO991A, PRO993A, THR1198C
• B-C: ARG1050B, ARG1050C, ARG1058B, ARG1058C, ARG1082B, ARG1082C, ARG1085B, ARG1085C, ARG1087B, ARG1087C, ARG1094B, ASN1083B, ASN1083C, ASN1086B, ASN1086C, ASN1091B, ASN1091C, ASP1035B, ASP1035C, ASP1036B, ASP1036C, ASP1054B, ASP1054C, ASP1056B, ASP1056C, CYS1037B, CYS1084B, CYS1084C, GLN1090C, GLU1062B, GLU1062C, GLY1057B, GLY1057C, ILE1034B, LEU1060B, LEU1060C, LEU1200C, LYS1055B, LYS1055C, PRO1061B, PRO1061C, PRO1116C, PRO1117C, SER1038B, SER1038C, SER1039B, TRP1081B, TRP1081C, TYR1053B, TYR1053C, VAL1088B, VAL1088C
• B-D: ARG1096D, ARG1199B, ARG981D, ASP1054B, ASP1114B, GLN1113D, GLU1062B, GLU1202B, GLU1205B, ILE990D, LEU1059B, LEU1060B, LEU1112D, LEU1200B, PRO1061B, PRO1116B, PRO1117B, PRO991D
• C-D: ALA1077C, ALA1077D, ALA1184D, ALA984C, ALA984D, ARG1023C, ARG1023D, ARG1082C, ARG1082D, ARG1087C, ARG1087D, ARG1137C, ARG1137D, ARG981C, ARG981D, ARG985C, ARG985D, ARG989D, ASN1013C, ASN1013D, ASN1020C, ASN1020D, ASN1024C, ASN1024D, ASN1075C, ASN1075D, ASN1083C, ASN1083D, ASP1022C, ASP1022D, ASP982C, ASP982D, CYS1014C, CYS1014D, CYS1031C, CYS1031D, CYS1033C, CYS1074C, CYS1074D, CYS1078C, CYS1078D, CYS1080C, CYS1080D, CYS1084C, CYS1084D, GLN1012C, GLN1012D, GLN1090C, GLN1090D, GLU1127C, GLU1127D, GLU988C, GLU988D, GLY986C, GLY986D, HIS1027C, HIS1027D, HIS1076C, HIS1076D, ILE1021C, ILE1021D, ILE1025C, ILE1025D, ILE1034C, ILE983C, ILE983D, ILE992C, ILE992D, LEU1028C, LEU1028D, LYS1008C, LYS1008D, MET1019C, MET1019D, PHE1160C, PHE1160D, PRO1018C, PRO1018D, PRO991C, PRO991D, PRO993C, PRO993D, SER1011C, SER1011D, SER1017C, SER1017D, SER1079C, SER1079D, SER980C, SER980D, THR1016C, THR1016D, THR1026C, THR1026D, TRP1081C, TRP1081D, TYR1009C, TYR1009D, TYR1030C, TYR1030D, TYR1161C, TYR1161D, TYR987C, TYR987D, VAL1010C, VAL1010D, VAL1015C, VAL1015D, VAL1032C, VAL1032D