3MMP

structure of the qb replicase, an rna-dependent rna polymerase consisting of viral and host proteins

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: G-F
  • Int. Res.: 81
  • Norm. En. per Res.: -5.396
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-G	-87.3404	-89.3526	-703.055	-879.748	247	38	16	27418	13	67	77
A-C	0.0	0.7392	-45.8762	-45.137	30	2	1	1796	0	6	7
G-F	-12.3187	-191.3137	-233.44	-437.0724	81	13	4	8507	9	36	18
C-F	-103.7508	-78.4917	-738.122	-920.3646	251	45	18	28259	13	66	76

Interface residues

• A-G: ALA1095A, ALA1096A, ALA1375A, ALA1385A, ALA174A, ALA189G, ALA192G, ALA201A, ALA211A, ALA40G, ALA433G, ALA443G, ALA482G, ALA504G, ALA536G, ALA540G, ALA566G, ALA573G, ARG1223A, ARG1230A, ARG1262A, ARG1283A, ARG1288A, ARG1318A, ARG1327A, ARG1333A, ARG1373A, ARG1377A, ARG1381A, ARG150G, ARG191G, ARG218A, ARG442G, ARG485G, ARG489G, ARG503G, ARG516G, ARG547G, ARG570G, ARG67G, ASN1090A, ASN1273A, ASN479G, ASN484G, ASN549G, ASP1086A, ASP1216A, ASP1314A, ASP1336A, ASP436G, ASP440G, ASP512G, ASP534G, ASP537G, ASP542G, ASP64G, ASP65G, CYS152G, CYS517G, CYS546G, CYS567G, GLN1329A, GLN197A, GLN203A, GLN231A, GLN243A, GLN543G, GLU1215A, GLU1259A, GLU1272A, GLU1315A, GLU1348A, GLU1378A, GLU209A, GLU212A, GLU216A, GLU225A, GLU236A, GLU502G, GLU505G, GLY1094A, GLY1224A, GLY1229A, GLY1275A, GLY1316A, GLY1317A, GLY1325A, GLY1379A, GLY1380A, GLY1384A, GLY1386A, GLY205A, GLY217A, GLY224A, GLY230A, GLY437G, GLY486G, GLY507G, GLY61G, HIS1319A, HIS171A, HIS195G, HIS444G, ILE1092A, ILE1214A, ILE1220A, ILE1310A, ILE1341A, ILE1376A, ILE200A, ILE210A, ILE435G, ILE478G, ILE488G, ILE541G, ILE545G, ILE565G, LEU1212A, LEU1264A, LEU1265A, LEU1277A, LEU1311A, LEU1343A, LEU1372A, LEU149G, LEU190G, LEU477G, LEU506G, LEU510G, LEU513G, LEU518G, LEU538G, LEU544G, LEU572G, LYS1089A, LYS1263A, LYS1313A, LYS1324A, LYS176A, LYS206A, LYS213A, LYS220A, LYS221A, LYS239A, LYS483G, LYS552G, MET1091A, MET1260A, MET148G, MET202A, MET214A, MET219A, MET235A, PHE1218A, PHE1261A, PHE1322A, PHE1323A, PHE1332A, PHE1374A, PHE154G, PHE173G, PHE196G, PHE222A, PHE231G, PHE232G, PHE233A, PHE514G, PHE539G, PHE66G, PRO1213A, PRO1321A, PRO1328A, PRO177A, PRO207A, PRO232A, PRO237A, PRO441G, PRO464G, PRO480G, PRO550G, PRO63G, SER1065A, SER1219A, SER1221A, SER1312A, SER170G, SER175A, SER193G, SER204A, SER227A, SER238A, SER403G, SER475G, SER508G, SER515G, SER519G, SER535G, SER548G, SER568G, SER569G, THR1064A, THR1093A, THR1225A, THR1228A, THR1320A, THR1334A, THR1335A, THR1338A, THR1340A, THR1382A, THR194G, THR198G, THR223A, THR240A, THR434G, THR551G, THR62G, TRP228G, TRP439G, TRP487G, TYR1309A, TYR1326A, TYR1331A, TYR402G, TYR41G, TYR430G, TYR467G, TYR490G, TYR509G, TYR511G, VAL1217A, VAL1226A, VAL1227A, VAL1231A, VAL1258A, VAL1274A, VAL1276A, VAL1383A, VAL1387A, VAL145G, VAL215A, VAL226A, VAL234A, VAL405G, VAL438G, VAL476G, VAL571G
• A-C: ALA1036A, ALA1036C, ALA1182C, ASP1070A, ASP1070C, GLU1185C, GLY1040A, GLY1040C, GLY1041A, GLY1041C, LEU1035A, LEU1035C, LEU1189A, LEU1189C, LYS1009A, LYS1009C, LYS1037A, LYS1037C, PRO1072A, PRO1072C, THR1038A, THR1038C, THR1071A, THR1071C, THR1073A, THR1073C, TYR1039A, TYR1039C, VAL1034A, VAL1034C
• G-F: ALA131F, ALA131G, ALA367F, ALA367G, ALA370F, ALA370G, ARG132F, ARG132G, ARG133F, ARG133G, ARG372F, ARG372G, ASN120F, ASN120G, ASP348F, ASP348G, ASP350F, ASP350G, CYS127F, CYS127G, CYS344F, CYS344G, CYS366F, CYS366G, GLU125F, GLU125G, GLU345F, GLU345G, GLU353F, GLU353G, GLU373F, GLU373G, GLY124F, GLY124G, HIS129F, HIS129G, ILE128F, ILE128G, ILE346F, ILE346G, LEU123F, LEU123G, LEU289F, LEU289G, LEU290F, LEU347F, LEU347G, LEU349F, LEU349G, LEU371F, LEU371G, LYS134F, LYS134G, LYS137F, LYS137G, MET130F, MET130G, PHE119F, PHE119G, PHE121F, PHE121G, PRO364F, PRO364G, PRO369F, PRO369G, SER122F, SER122G, SER126F, SER126G, SER342F, SER342G, SER351F, SER351G, SER352F, SER352G, VAL343F, VAL343G, VAL368F, VAL368G, VAL374F, VAL374G
• C-F: ALA1095C, ALA1096C, ALA1375C, ALA1385C, ALA174C, ALA189F, ALA192F, ALA201C, ALA211C, ALA40F, ALA433F, ALA443F, ALA482F, ALA504F, ALA536F, ALA540F, ALA566F, ALA573F, ARG1223C, ARG1230C, ARG1262C, ARG1283C, ARG1288C, ARG1318C, ARG1327C, ARG1333C, ARG1373C, ARG1377C, ARG1381C, ARG150F, ARG191F, ARG218C, ARG442F, ARG485F, ARG489F, ARG503F, ARG516F, ARG547F, ARG570F, ARG67F, ASN1090C, ASN1273C, ASN479F, ASN484F, ASN549F, ASP1086C, ASP1216C, ASP1314C, ASP1336C, ASP197F, ASP406F, ASP436F, ASP440F, ASP512F, ASP534F, ASP537F, ASP542F, ASP64F, ASP65F, CYS152F, CYS517F, CYS533F, CYS546F, CYS567F, GLN1329C, GLN197C, GLN203C, GLN231C, GLN243C, GLN543F, GLU1215C, GLU1259C, GLU1272C, GLU1315C, GLU1348C, GLU1378C, GLU209C, GLU212C, GLU216C, GLU225C, GLU236C, GLU502F, GLU505F, GLY1094C, GLY1224C, GLY1229C, GLY1275C, GLY1316C, GLY1317C, GLY1325C, GLY1339C, GLY1379C, GLY1380C, GLY1384C, GLY1386C, GLY205C, GLY217C, GLY224C, GLY230C, GLY437F, GLY486F, GLY507F, GLY61F, HIS1319C, HIS171C, HIS195F, HIS444F, ILE1092C, ILE1214C, ILE1220C, ILE1310C, ILE1341C, ILE1376C, ILE200C, ILE210C, ILE435F, ILE478F, ILE488F, ILE541F, ILE545F, ILE565F, LEU1212C, LEU1264C, LEU1265C, LEU1277C, LEU1311C, LEU1343C, LEU1372C, LEU149F, LEU190F, LEU477F, LEU506F, LEU510F, LEU513F, LEU518F, LEU538F, LEU544F, LEU572F, LYS1089C, LYS1263C, LYS1313C, LYS1324C, LYS176C, LYS206C, LYS213C, LYS220C, LYS221C, LYS239C, LYS483F, LYS552F, MET1091C, MET1260C, MET148F, MET202C, MET214C, MET219C, MET235C, PHE1218C, PHE1261C, PHE1322C, PHE1323C, PHE1332C, PHE1374C, PHE154F, PHE173F, PHE196F, PHE222C, PHE231F, PHE232F, PHE233C, PHE514F, PHE539F, PHE66F, PRO1213C, PRO1321C, PRO1328C, PRO177C, PRO207C, PRO232C, PRO237C, PRO441F, PRO464F, PRO480F, PRO550F, PRO63F, SER1065C, SER1219C, SER1221C, SER1312C, SER170F, SER175C, SER193F, SER204C, SER227C, SER238C, SER403F, SER475F, SER508F, SER515F, SER519F, SER535F, SER548F, SER568F, SER569F, THR1064C, THR1093C, THR1225C, THR1228C, THR1320C, THR1334C, THR1335C, THR1338C, THR1340C, THR1382C, THR194F, THR198F, THR223C, THR240C, THR434F, THR551F, THR62F, TRP228F, TRP439F, TRP487F, TYR1309C, TYR1326C, TYR1331C, TYR402F, TYR41F, TYR467F, TYR490F, TYR509F, TYR511F, VAL1217C, VAL1226C, VAL1227C, VAL1231C, VAL1258C, VAL1274C, VAL1276C, VAL1383C, VAL1387C, VAL145F, VAL215C, VAL226C, VAL234C, VAL405F, VAL407F, VAL438F, VAL476F, VAL571F