3ML6

a complex between dishevlled2 and clathrin adaptor ap-2

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: B-F
  • Int. Res.: 112
  • Norm. En. per Res.: -3.7218
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-35.2082	-2.8645	-131.869	-169.9417	61	18	2	5601	0	8	15
A-D	-21.5547	10.4384	-62.3065	-73.4228	51	9	0	2820	0	19	19
A-E	-69.0278	26.7626	-383.07	-425.3352	118	31	13	14634	0	36	33
A-F	-17.4833	-2.5962	-151.49	-171.5695	57	8	2	5686	0	6	15
B-E	-27.4324	-3.4556	-148.054	-178.9421	59	13	2	5773	0	7	15
B-F	-89.7894	31.6862	-358.743	-416.8462	112	34	13	14187	0	38	33
E-F	0.0	0.0	-0.2514	-0.2514	3	0	0	53	0	0	1

Interface residues

• A-C: ALA1342C, ALA1368C, ALA452A, ARG1294C, ARG440A, ARG442A, ARG476A, ASN1412A, ASN493A, ASP457A, ASP460A, CYS1337C, CYS501A, GLN1334C, GLN1365C, GLN500A, GLU1363C, GLU1369C, GLU499A, GLY1340C, GLY455A, HIS490A, ILE1307C, ILE1336C, ILE1351C, ILE1366C, ILE447A, ILE449A, ILE495A, LEU445A, LEU454A, LYS1304C, LYS1308C, LYS1339C, LYS1341C, LYS1343C, LYS1356C, LYS1362C, LYS446A, LYS494A, MET1338C, MET443A, PHE1407A, PHE453A, SER1364C, SER1367C, SER456A, SER498A, THR491A, THR496A, TRP1353C, TRP444A, TYR1344C, TYR502A, TYR503A, VAL1303C, VAL1305C, VAL1306C, VAL1335C, VAL1352C, VAL492A
• A-D: ALA1382A, ALA424D, ALA485D, ARG1288A, ARG1294A, ARG1298A, ARG1383A, ARG1434A, ARG473D, ARG476D, ASP1377A, ASP422D, CYS1435A, GLN1188A, GLN1190A, GLU1295A, GLU467D, GLU471D, GLU474D, GLY1189A, GLY1297A, GLY468D, GLY481D, GLY510D, LEU1184A, LEU1192A, LEU1292A, LEU487D, LEU508D, LYS1378A, LYS1379A, LYS1380A, LYS428D, LYS477D, LYS484D, MET1185A, MET421D, MET423D, PHE469D, PRO1187A, PRO1291A, PRO470D, SER1186A, SER425D, SER480D, SER509D, THR1375A, TRP1381A, TYR478D, VAL1293A, VAL426D
• A-E: ARG1170A, ARG1170E, ARG1357E, ARG1402A, ARG1402E, ARG1423A, ARG1423E, ARG1427A, ASN1171A, ASN1171E, ASN1217A, ASN1217E, ASP1176A, ASP1176E, ASP1415E, ASP1417A, ASP1417E, GLN1154A, GLN1318A, GLN1318E, GLU1160A, GLU1160E, GLU1162A, GLU1162E, GLU1172A, GLU1172E, GLU1391A, GLU1391E, GLY1164A, GLY1164E, GLY1165A, GLY1165E, GLY1167A, GLY1167E, GLY1168A, GLY1168E, GLY1215A, GLY1215E, GLY1426A, GLY1426E, HIS1159A, HIS1159E, ILE1419A, ILE1419E, ILE1425A, ILE1425E, LEU1161A, LEU1161E, LEU1173A, LEU1173E, LEU1175A, LEU1175E, LEU1178A, LEU1178E, LEU1315A, LEU1315E, LEU1404A, LEU1404E, LYS1203A, LYS1203E, LYS1312A, LYS1312E, LYS1319A, LYS1319E, LYS1356E, LYS1400A, LYS1400E, LYS1405A, LYS1405E, LYS1410A, LYS1420A, LYS1420E, MET1202A, MET1202E, MET1216E, PHE1163A, PHE1163E, PHE1174A, PHE1174E, PHE1214A, PHE1214E, PRO1153A, PRO1155A, PRO1155E, PRO1156A, PRO1156E, PRO1157A, PRO1157E, PRO1393A, PRO1393E, SER1166A, SER1166E, SER1169A, SER1169E, SER1314E, TRP1421A, TRP1421E, TYR1158A, TYR1158E, TYR1205A, TYR1205E, TYR1403A, TYR1403E, TYR1424A, TYR1424E, VAL1177A, VAL1177E, VAL1201A, VAL1201E, VAL1392A, VAL1392E, VAL1401A, VAL1401E, VAL1406E, VAL1418A, VAL1418E, VAL1422A, VAL1422E
• A-F: ALA1342A, ALA1368A, ALA452F, ARG442F, ARG476F, ARG489F, ASN493F, CYS1337A, CYS501F, GLN1334A, GLN1365A, GLN500F, GLU1363A, GLU499F, GLY1340A, GLY455F, HIS490F, ILE1307A, ILE1336A, ILE1351A, ILE1355A, ILE1366A, ILE447F, ILE449F, ILE495F, LEU445F, LEU454F, LYS1304A, LYS1308A, LYS1339A, LYS1341A, LYS1343A, LYS1354A, LYS1356A, LYS1362A, LYS446F, LYS494F, MET1338A, MET443F, PHE1407F, PHE453F, PHE497F, SER1364A, SER1367A, SER456F, SER498F, THR491F, THR496F, TRP1353A, TRP444F, TYR502F, TYR503F, VAL1305A, VAL1306A, VAL1335A, VAL492F, VAL504F
• B-E: ALA1342B, ALA1368B, ALA452E, ARG440E, ARG442E, ARG489E, ASN493E, ASP457E, CYS1337B, CYS501E, GLN1334B, GLN1365B, GLN500E, GLU1363B, GLU1369B, GLU499E, GLY1340B, GLY455E, HIS490E, ILE1290B, ILE1307B, ILE1336B, ILE1351B, ILE1355B, ILE1366B, ILE447E, ILE449E, LEU445E, LEU454E, LYS1304B, LYS1308B, LYS1339B, LYS1341B, LYS1343B, LYS1354B, LYS1356B, LYS1362B, LYS446E, LYS494E, MET1338B, MET443E, PHE1407E, PHE453E, SER1364B, SER1367B, SER456E, SER498E, THR491E, THR496E, TRP1353B, TRP444E, TYR1344B, TYR502E, TYR503E, VAL1305B, VAL1306B, VAL1335B, VAL492E, VAL504E
• B-F: ARG1170B, ARG1170F, ARG1402B, ARG1402F, ARG1423B, ARG1423F, ARG1427B, ARG1427F, ASN1171B, ASN1171F, ASN1217B, ASP1176B, ASP1176F, ASP1415F, ASP1417B, ASP1417F, GLN1318B, GLN1318F, GLU1160B, GLU1160F, GLU1162B, GLU1162F, GLU1172B, GLU1172F, GLU1271B, GLU1391B, GLU1391F, GLY1164B, GLY1164F, GLY1165B, GLY1165F, GLY1167B, GLY1167F, GLY1168B, GLY1168F, GLY1215B, GLY1215F, GLY1426F, HIS1159B, HIS1159F, ILE1419B, ILE1419F, ILE1425B, ILE1425F, LEU1161B, LEU1161F, LEU1173B, LEU1173F, LEU1175B, LEU1175F, LEU1178B, LEU1178F, LEU1315B, LEU1315F, LEU1316F, LEU1404B, LEU1404F, LYS1203B, LYS1203F, LYS1312B, LYS1319B, LYS1319F, LYS1400B, LYS1400F, LYS1405B, LYS1405F, LYS1420B, LYS1420F, MET1202B, MET1202F, PHE1163B, PHE1163F, PHE1174B, PHE1174F, PHE1214B, PHE1214F, PRO1155B, PRO1155F, PRO1156B, PRO1156F, PRO1157B, PRO1157F, PRO1393B, PRO1393F, SER1166B, SER1166F, SER1169B, SER1169F, TRP1421B, TRP1421F, TYR1158B, TYR1158F, TYR1205B, TYR1205F, TYR1403B, TYR1403F, TYR1424B, TYR1424F, VAL1177B, VAL1177F, VAL1201B, VAL1201F, VAL1392B, VAL1392F, VAL1401B, VAL1401F, VAL1406B, VAL1406F, VAL1418B, VAL1418F, VAL1422B, VAL1422F
• E-F: ILE495E, LYS484E, LYS484F