3MK3

crystal structure of lumazine synthase from salmonella typhimurium lt2

• Total interactions analyzed: 1770
• Total true interactions: 150
• Strongest Interaction:
  • Chains: d-j
  • Int. Res.: 48
  • Norm. En. per Res.: -4.0924
• Hub Node: A(9)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-48.8627	19.3806	-297.03	-326.5121	128	15	12	12936	1	15	13
A-E	-44.9862	10.8453	-290.627	-324.7679	129	23	12	12860	1	15	13
A-N	-13.0244	25.6782	-122.486	-109.8322	58	4	3	5068	2	6	14
A-v	-47.4465	-75.1553			12
A-w	-12.7988	27.2731			10
B-C	-43.8164	11.3704	-290.411	-322.857	128	18	12	12665	1	15	14
B-U	-37.784	-71.2303	-79.9073	-188.9216	53	10	3	3838	6	12	10
B-V	-14.5498	23.6388	-108.245	-99.156	57	5	3	4769	2	6	14
B-v	-12.4311	25.5023			10
C-D	-39.6951	12.7329	-276.455	-303.4173	126	14	11	12483	1	15	13
C-R	-48.4179	-72.5635	-80.2414	-201.2228	54	12	3	3958	6	12	11
C-S	-14.5612	23.4289	-110.294	-101.4262	58	4	3	4743	2	6	14
C-U	-5.8289	23.5979	-109.654	-91.885	57	5	3	4762	2	6	14
D-E	-49.5182	19.0175	-294.955	-325.4558	130	22	12	13007	1	15	13
D-F	-13.5644	24.4826	-116.181	-105.2628	58	6	3	4925	2	6	14
D-J	-44.8263	-72.1556	-79.1075	-196.0893	56	10	3	3947	6	12	12
D-R	-14.0961	23.8164	-114.74	-105.0196	56	5	3	4872	2	6	14
E-J	-12.9209	25.7361	-111.029	-98.2139	56	5	3	4748	2	6	14
E-N	-45.6337	-72.8872	-82.3633	-200.8842	56	13	3	3993	6	12	11
E-O	-14.696	27.2216	-123.714	-111.1884	57	5	3	4929	2	6	15
F-G	-36.5735	18.3761	-295.353	-313.5503	127	15	13	12683	1	15	13
F-J	-37.7876	14.5234	-290.407	-313.6712	127	20	12	12731	1	15	13
F-Q	-48.8996	-74.7738	-81.7525	-205.4258	55	12	3	3955	6	12	10
F-R	-5.1731	24.7062	-107.49	-87.9569	57	5	3	4749	2	6	14
G-H	-45.9542	12.3937	-284.666	-318.2265	127	24	12	12668	1	15	13
G-Q	-13.1317	24.9972	-109.254	-97.3885	57	5	3	4764	2	6	14
G-f	-49.028	-72.3521	-73.6862	-195.0663	51	12	3	3875	6	12	11
G-g	-15.4557	27.5052	-124.111	-112.0615	58	9	3	4997	2	6	15
H-I	-34.4618	19.7522	-303.406	-318.1156	130	15	13	12886	1	15	13
H-c	-39.8894	-69.8259	-74.2465	-183.9617	49	7	3	3712	6	12	10
H-d	-7.3899	26.5015	-112.045	-92.9334	57	5	3	4775	2	6	14
H-f	-12.3749	27.7244	-122.168	-106.8184	57	9	3	5137	2	6	14
I-J	-43.2579	11.881	-284.552	-315.9289	126	19	12	12506	1	15	13
I-K	-12.7425	26.2507	-112.496	-98.9878	56	3	3	4710	2	6	15
I-O	-46.5927	-73.6076	-83.1352	-203.3355	55	12	3	3954	6	12	12
I-c	-9.0531	26.4787	-109.911	-92.4855	56	6	3	4751	2	6	14
J-O	-6.6019	25.7407	-111.052	-91.9132	58	9	3	4974	2	6	14
K-L	-46.0078	17.8593	-300.876	-329.0245	129	17	13	12878	1	15	12
K-O	-45.9018	17.9506	-295.075	-323.0262	129	22	12	13065	1	15	13
K-b	-52.0842	-78.8731	-88.5473	-219.5046	55	13	3	4141	6	12	14
K-c	-12.1827	25.1786	-116.52	-103.5241	56	8	3	4934	2	6	14
L-M	-57.802	20.8025	-305.097	-342.0966	128	22	12	13118	1	15	14
L-b	-6.467	24.6582	-105.238	-87.0468	57	8	3	4694	2	6	14
L-k	-49.5322	-72.3166			12
L-l	-10.2286	26.8878			10
M-N	-40.646	19.4471	-282.059	-303.2578	128	17	12	12613	1	15	13
M-k	-13.1144	24.6316			10
M-w	-48.2669	-74.7102			12
M-x	-16.2886	25.8326			10
N-O	-44.3933	19.8311	-284.903	-309.4652	126	16	12	12500	1	15	13
N-w	-14.9171	28.6322			10
P-Q	-44.2152	12.7165	-282.476	-313.9746	126	19	12	12570	1	15	13
P-T	-43.7258	17.8875	-308.973	-334.8114	127	20	13	13079	1	15	14
P-3	-14.3186	25.879	-117.503	-105.9426	58	9	3	5125	2	6	15
P-g	-41.0521	-71.4982	-78.3615	-190.9118	53	11	3	3878	6	12	12
P-h	-14.4035	25.032	-103.356	-92.7275	55	2	3	4484	2	6	14
Q-R	-46.7064	19.1092	-304.756	-332.3533	130	18	13	13126	1	15	13
Q-g	-5.965	24.2402	-101.929	-83.6539	57	8	2	4745	2	6	14
R-S	-44.5144	12.8235	-287.724	-319.4148	128	20	12	12678	1	15	13
S-T	-51.0184	21.6763	-289.967	-319.3091	129	20	12	12918	1	15	13
S-U	-12.6285	24.3186	-106.133	-94.4428	57	4	3	4660	2	6	14
S-Y	-41.1819	-68.8686	-82.3276	-192.3781	53	10	3	3855	6	12	11
T-Y	-7.0871	22.1592	-103.732	-88.6599	58	6	3	4650	2	6	14
T-3	-49.4702	-77.0714	-80.7508	-207.2924	56	15	3	4121	6	12	13
T-4	-7.1647	21.9111	-104.289	-89.5426	57	7	3	4666	2	6	14
U-V	-42.7752	20.4659	-309.246	-331.5553	130	23	13	13254	1	15	14
U-Y	-49.7546	13.1109	-301.001	-337.6447	129	29	12	13163	1	16	14
V-W	-42.1576	12.7418	-275.355	-304.7708	129	27	12	12712	1	15	13
V-u	-40.8901	-74.3926			12
V-v	-8.1121	21.9847			8
W-X	-58.1085	19.9107	-312.065	-350.2627	130	31	12	13346	1	16	14
W-r	-48.5093	-82.092			18
W-s	-7.4236	23.3566			8
W-u	-13.5848	24.1008			10
X-Y	-28.5877	18.881	-294.063	-303.7697	129	14	12	12738	1	15	13
X-Z	-13.6605	25.4298	-117.774	-106.0046	58	7	3	4937	2	6	15
X-4	-49.3163	-72.2148	-79.6109	-201.142	55	14	3	3911	6	12	10
X-r	-16.7207	26.7117			13
Y-4	-15.1938	24.8914	-112.294	-102.5964	57	5	3	4816	2	6	15
Z-1	-48.9851	21.4854	-292.629	-320.1286	127	17	12	12951	1	15	13
Z-4	-48.433	19.1667	-303.777	-333.0433	129	22	13	13084	1	15	13
Z-q	-47.1587	-77.2275			12
Z-r	-13.7932	24.5696			11
1-2	-41.5077	17.3043	-290.848	-315.0514	128	20	12	12822	1	15	13
1-5	-40.9251	-68.578	-80.286	-189.7891	53	13	3	3863	6	12	10
1-6	-13.2995	24.0235	-117.595	-106.871	58	3	3	4907	2	6	14
1-q	-7.5535	24.8479			8
2-3	-49.2292	19.9812	-287.696	-316.944	129	20	12	12722	1	15	13
2-5	-9.6994	28.1485	-117.454	-99.0049	57	7	3	4854	2	6	15
2-h	-47.8829	-78.8231	-81.4939	-208.1998	56	16	3	4126	6	12	13
2-i	-6.1636	24.281	-109.029	-90.9116	58	6	3	4751	2	6	14
3-4	-54.3316	19.2273	-310.351	-345.4553	130	22	13	13096	1	15	13
3-h	-7.0317	22.0756	-102.101	-87.0571	57	8	3	4602	2	6	14
5-6	-50.4817	14.7376	-291.801	-327.5451	126	22	12	12939	1	16	14
5-9	-50.0485	16.909	-311.484	-344.6236	131	23	13	13366	1	15	13
5-i	-13.6287	27.3051	-116.16	-102.4836	58	6	3	4944	2	6	14
6-7	-44.7092	18.4833	-294.562	-320.7879	126	17	12	12812	1	15	13
6-p	-47.2652	-69.531			12
6-q	-14.478	25.6944			10
7-8	-50.4556	20.092	-292.444	-322.8076	127	16	12	12752	1	15	13
7-m	-50.3721	-75.7326			12
7-n	-13.6288	24.3442			10
7-p	-12.5823	26.47			9
8-9	-46.8292	18.4786	-291.517	-319.8676	128	16	12	12845	1	15	13
8-a	-14.0009	25.0594	-120.642	-109.5834	57	7	3	4982	2	6	14
8-e	-41.1867	-69.1102	-84.071	-194.3679	54	12	3	3909	6	12	10
8-m	-12.417	25.5472			10
9-e	-9.8215	25.4907	-111.544	-95.8748	58	5	3	4796	2	6	14
9-i	-48.0517	-76.532	-85.0307	-209.6144	56	12	3	4062	6	12	12
9-j	-6.9733	23.5209	-110.65	-94.1024	57	10	3	4819	2	6	14
a-b	-48.9791	13.0405	-292.724	-328.6626	127	24	12	12814	1	15	13
a-e	-40.578	21.2556	-289.409	-308.7313	127	16	12	12697	1	15	13
a-l	-41.0043	-74.9451			13
a-m	-14.4106	22.8705			10
b-c	-55.2728	18.6826	-298.637	-335.2271	128	20	12	12942	1	15	14
b-l	-7.7392	22.1173			8
c-d	-48.1725	11.6649	-294.905	-331.4125	127	19	12	12743	1	15	13
d-e	-42.8035	19.2455	-283.217	-306.775	126	16	11	12435	1	15	13
d-f	-16.7243	27.0261	-129.679	-119.3772	59	7	3	5225	2	7	15
d-j	-50.0595	-69.0665	-77.3108	-196.4368	48	8	3	3684	6	12	10
e-j	-11.9713	25.9317	-119.177	-105.2165	57	6	3	4985	2	6	14
f-g	-43.8679	19.6132	-279.749	-304.0037	129	16	12	12494	1	15	13
f-j	-43.9404	13.1257	-249.826	-280.6408	119	21	6	10288	1	14	13
g-h	-58.2475	16.3725	-324.351	-366.226	131	29	13	13735	1	15	13
h-i	-48.0438	15.9805	-299.639	-331.7023	129	16	12	12978	1	15	13
i-j	-46.3472	21.685	-294.125	-318.7872	128	18	12	12738	1	15	13
k-l	-34.1293	15.9627			19
k-o	-48.8348	19.1378			18
k-x	-10.6201	29.3298			9
l-m	-52.0091	10.246			16
m-n	-46.1364	21.7587			22
n-o	-37.4936	18.873			18
n-p	-12.7495	25.4995			10
n-t	-40.837	-71.0382			12
o-t	-14.5661	25.8501			10
o-x	-43.869	-71.4881			12
o-y	-12.6402	26.1852			9
p-q	-46.467	20.3365			18
p-t	-44.6286	11.4136			16
q-r	-50.018	17.6686			20
r-s	-46.3511	20.9299			17
s-t	-57.1595	19.7405			22
s-u	-13.4784	26.4895			10
s-y	-48.8951	-72.2844			12
t-y	-12.6507	26.6231			10
u-v	-52.6024	20.3762			18
u-y	-36.4096	17.7567			18
v-w	-55.9095	17.7157			22
w-x	-40.8006	14.6992			17
x-y	-47.7982	12.8805			18

Interface residues

• A-B: ALA102A, ALA102B, ALA105A, ALA113A, ALA125A, ALA140A, ALA144A, ALA153A, ALA16B, ALA57B, ALA63B, ALA66B, ALA68B, ALA6A, ALA75A, ALA78A, ALA88B, ALA94A, ALA97A, ALA97B, ARG128A, ARG14B, ARG21B, ARG84A, ASN2A, ASN48B, ASN7A, ASN99A, ASN99B, ASP107A, ASP107B, ASP28B, ASP32B, ASP36B, ASP46B, ASP47B, ASP74A, GLN106A, GLN106B, GLN124A, GLN24B, GLU120A, GLU127A, GLU139A, GLU146A, GLU59B, GLU65B, GLU91A, GLU91B, GLY100A, GLY100B, GLY109A, GLY115A, GLY56B, GLY85B, GLY86B, GLY95A, GLY95B, GLY96A, GLY96B, HIS89B, ILE148A, ILE154A, ILE17B, ILE19B, ILE3A, ILE49B, ILE4A, ILE83A, LEU101A, LEU101B, LEU117A, LEU142A, LEU145A, LEU151A, LEU31B, LEU38B, LEU60B, LEU62B, LEU67B, LYS136A, LYS45B, LYS5A, LYS69B, LYS72B, MET147A, MET1A, PHE114A, PHE22B, PHE90A, PHE90B, PRO111A, PRO55B, PRO61B, SER103A, SER103B, SER108A, SER121A, SER70B, SER98A, THR118A, THR119A, THR143A, THR18B, THR39B, THR50B, THR64B, THR87B, TRP53B, TYR58B, TYR73B, TYR92A, TYR92B, VAL104A, VAL104B, VAL110A, VAL112A, VAL116A, VAL150A, VAL15B, VAL35B, VAL51B, VAL52B, VAL54B, VAL82A, VAL8A, VAL93A, VAL93B
• A-E: ALA102E, ALA105E, ALA113E, ALA125E, ALA140E, ALA144E, ALA153E, ALA16A, ALA57A, ALA63A, ALA66A, ALA68A, ALA6E, ALA75E, ALA78E, ALA88A, ALA94A, ALA94E, ALA97A, ALA97E, ARG128E, ARG14A, ARG21A, ARG84E, ASN2E, ASN48A, ASN7E, ASN99A, ASN99E, ASP107A, ASP107E, ASP28A, ASP32A, ASP36A, ASP46A, ASP47A, ASP74E, GLN106A, GLN106E, GLN124E, GLN24A, GLU120E, GLU127E, GLU139E, GLU146E, GLU59A, GLU65A, GLU91A, GLU91E, GLY100A, GLY100E, GLY109E, GLY115E, GLY56A, GLY85A, GLY86A, GLY95A, GLY95E, GLY96A, GLY96E, HIS89A, HIS89E, ILE148E, ILE154E, ILE17A, ILE19A, ILE3E, ILE49A, ILE4E, ILE83E, LEU101A, LEU101E, LEU117E, LEU142E, LEU145E, LEU151E, LEU31A, LEU38A, LEU60A, LEU62A, LEU67A, LYS136E, LYS45A, LYS5E, LYS69A, LYS72A, MET147E, MET1E, PHE114E, PHE22A, PHE90A, PHE90E, PRO111E, PRO55A, PRO61A, SER103A, SER103E, SER108E, SER121E, SER70A, SER98E, THR118E, THR119E, THR143E, THR18A, THR39A, THR50A, THR64A, THR87A, TRP53A, TYR58A, TYR73A, TYR92A, TYR92E, VAL104A, VAL104E, VAL110E, VAL112E, VAL116E, VAL150E, VAL15A, VAL35A, VAL51A, VAL52A, VAL54A, VAL82E, VAL8E, VAL93A, VAL93E
• A-N: ALA125A, ALA125N, ALA129N, ALA133N, ALA138N, ALA34N, ALA37N, ARG128N, ARG21A, ARG40N, ARG84A, ASN135N, ASN23A, ASN27A, ASN27N, ASP28A, ASP28N, ASP32N, ASP36N, GLN124N, GLN24A, GLN24N, GLU120A, GLU123A, GLU123N, GLU127N, GLY130N, GLY134N, GLY33N, GLY85A, GLY86A, ILE122A, ILE122N, ILE126A, ILE126N, ILE26A, ILE26N, ILE41N, ILE83A, LEU30N, LEU31N, LYS132N, PHE22A, PHE25A, PHE25N, PHE90A, PRO55A, SER121A, SER29N, THR119A, THR131A, THR131N, THR39N, THR81A, THR87A, TRP53A, VAL54A, VAL82A
• A-v: ALA6A, ALA6v, ARG40A, ARG40v, ASN7A, ASN7v, ASP36A, ASP36v, GLU146A, GLU146v, LYS5A, LYS5v
• A-w: ARG21w, ARG40A, ASP28A, ASP28w, ASP32A, ASP36A, GLU123A, GLU123w, GLY130A, PHE25w
• B-C: ALA102B, ALA105B, ALA113B, ALA125B, ALA133B, ALA140B, ALA144B, ALA153B, ALA16C, ALA57C, ALA63C, ALA66C, ALA68C, ALA6B, ALA75B, ALA78B, ALA88C, ALA94B, ALA97B, ALA97C, ARG128B, ARG14C, ARG21C, ARG84B, ASN2B, ASN48C, ASN7B, ASN99B, ASN99C, ASP107B, ASP107C, ASP28C, ASP32C, ASP36C, ASP46C, ASP47C, ASP74B, GLN106B, GLN106C, GLN124B, GLN24C, GLU120B, GLU127B, GLU139B, GLU146B, GLU59C, GLU65C, GLU91B, GLU91C, GLY100B, GLY100C, GLY109B, GLY115B, GLY56C, GLY85C, GLY86C, GLY95B, GLY95C, GLY96B, GLY96C, HIS89C, ILE148B, ILE154B, ILE17C, ILE19C, ILE3B, ILE49C, ILE4B, ILE83B, LEU101B, LEU101C, LEU117B, LEU142B, LEU145B, LEU151B, LEU31C, LEU38C, LEU60C, LEU62C, LEU67C, LYS136B, LYS45C, LYS5B, LYS69C, LYS72C, MET147B, MET1B, PHE114B, PHE22C, PHE90B, PHE90C, PRO111B, PRO55C, PRO61C, SER103B, SER103C, SER108B, SER121B, SER70C, SER98B, THR118B, THR119B, THR143B, THR18C, THR39C, THR50C, THR64C, THR87C, TRP53C, TYR58C, TYR73C, TYR92B, TYR92C, VAL104B, VAL104C, VAL110B, VAL112B, VAL116B, VAL150B, VAL15C, VAL35C, VAL51C, VAL52C, VAL54C, VAL82B, VAL8B, VAL93B, VAL93C
• B-U: ALA10B, ALA10U, ALA133B, ALA133U, ALA37B, ALA37U, ALA6B, ALA6U, ALA9B, ALA9U, ARG128B, ARG128U, ARG40B, ARG40U, ASN149B, ASN149U, ASN7B, ASN7U, ASP32B, ASP32U, ASP36B, ASP36U, GLN43B, GLN43U, GLU146B, GLU146U, GLY33B, GLY33U, GLY42B, GLY42U, ILE41B, ILE41U, ILE4B, ILE4U, LEU142B, LEU142U, LEU38B, LEU38U, LYS132B, LYS132U, LYS5B, LYS5U, PRO11B, PRO11U, THR143B, THR143U, THR39B, THR39U, VAL150B, VAL150U, VAL44B, VAL8B, VAL8U
• B-V: ALA125B, ALA125V, ALA129B, ALA133B, ALA138B, ALA34B, ALA37B, ARG128B, ARG21V, ARG40B, ARG84V, ASN135B, ASN23V, ASN27B, ASN27V, ASP28B, ASP28V, ASP32B, ASP36B, GLN124B, GLN24B, GLN24V, GLU120V, GLU123B, GLU123V, GLU127B, GLY130B, GLY134B, GLY33B, GLY85V, GLY86V, ILE122B, ILE122V, ILE126B, ILE126V, ILE26B, ILE26V, ILE41B, ILE83V, LEU30B, LEU31B, LYS132B, PHE22V, PHE25B, PHE25V, PHE90V, PRO55V, SER121V, SER29B, THR131B, THR131V, THR39B, THR81V, THR87V, TRP53V, VAL54V, VAL82V
• B-v: ARG21B, ARG40v, ASP28B, ASP28v, ASP32v, ASP36v, GLU123B, GLU123v, GLY130v, PHE25B
• C-D: ALA102C, ALA105C, ALA113C, ALA125C, ALA140C, ALA144C, ALA153C, ALA16D, ALA57D, ALA63D, ALA66D, ALA68D, ALA6C, ALA75C, ALA78C, ALA88D, ALA94C, ALA97C, ALA97D, ARG128C, ARG14D, ARG21D, ARG84C, ASN2C, ASN48D, ASN7C, ASN99C, ASN99D, ASP107C, ASP107D, ASP28D, ASP32D, ASP36D, ASP46D, ASP47D, GLN106C, GLN106D, GLN124C, GLN24D, GLU120C, GLU127C, GLU139C, GLU146C, GLU59D, GLU65D, GLU91C, GLU91D, GLY100C, GLY100D, GLY109C, GLY115C, GLY56D, GLY85D, GLY86D, GLY95C, GLY95D, GLY96C, GLY96D, HIS89D, ILE148C, ILE154C, ILE17D, ILE19D, ILE3C, ILE49D, ILE4C, ILE83C, LEU101C, LEU101D, LEU117C, LEU142C, LEU145C, LEU151C, LEU31D, LEU38D, LEU60D, LEU62D, LEU67D, LYS136C, LYS45D, LYS5C, LYS69D, LYS72D, MET147C, MET1C, PHE114C, PHE22D, PHE90C, PHE90D, PRO111C, PRO55D, PRO61D, SER103C, SER103D, SER108C, SER121C, SER70D, SER98C, THR118C, THR119C, THR143C, THR18D, THR39D, THR50D, THR64D, THR87D, TRP53D, TYR58D, TYR73D, TYR92C, TYR92D, VAL104C, VAL104D, VAL110C, VAL112C, VAL116C, VAL150C, VAL15D, VAL35D, VAL51D, VAL52D, VAL54D, VAL82C, VAL8C, VAL93C, VAL93D
• C-R: ALA10C, ALA10R, ALA133C, ALA133R, ALA37C, ALA37R, ALA6C, ALA6R, ALA9C, ALA9R, ARG128C, ARG128R, ARG40C, ARG40R, ASN149C, ASN149R, ASN7C, ASN7R, ASP32C, ASP32R, ASP36C, ASP36R, GLN43C, GLN43R, GLU146C, GLU146R, GLY33C, GLY33R, GLY42C, GLY42R, ILE41C, ILE41R, ILE4C, ILE4R, LEU142C, LEU142R, LEU38C, LEU38R, LYS132C, LYS132R, LYS5C, LYS5R, PRO11C, PRO11R, THR143C, THR143R, THR39C, THR39R, VAL150C, VAL150R, VAL44C, VAL44R, VAL8C, VAL8R
• C-S: ALA125C, ALA125S, ALA129C, ALA133C, ALA138C, ALA34C, ALA37C, ARG128C, ARG21S, ARG40C, ARG84S, ASN135C, ASN23S, ASN27C, ASN27S, ASP28C, ASP28S, ASP32C, ASP36C, GLN124C, GLN24C, GLN24S, GLU120S, GLU123C, GLU123S, GLU127C, GLY130C, GLY134C, GLY33C, GLY85S, GLY86S, ILE122C, ILE122S, ILE126C, ILE126S, ILE26C, ILE26S, ILE41C, ILE83S, LEU30C, LEU31C, LYS132C, PHE22S, PHE25C, PHE25S, PHE90S, PRO55S, SER121S, SER29C, THR119S, THR131C, THR131S, THR39C, THR81S, THR87S, TRP53S, VAL54S, VAL82S
• C-U: ALA125C, ALA125U, ALA129U, ALA133U, ALA138U, ALA34U, ALA37U, ARG128U, ARG21C, ARG40U, ARG84C, ASN135U, ASN23C, ASN27C, ASN27U, ASP28C, ASP28U, ASP32U, ASP36U, GLN124U, GLN24C, GLN24U, GLU120C, GLU123C, GLU123U, GLU127U, GLY130U, GLY134U, GLY33U, GLY85C, GLY86C, ILE122C, ILE122U, ILE126C, ILE126U, ILE26C, ILE26U, ILE41U, ILE83C, LEU30U, LEU31U, LYS132U, PHE22C, PHE25C, PHE25U, PHE90C, PRO55C, SER121C, SER29U, THR119C, THR131C, THR131U, THR81C, THR87C, TRP53C, VAL54C, VAL82C
• D-E: ALA102D, ALA102E, ALA105D, ALA113D, ALA125D, ALA140D, ALA144D, ALA153D, ALA16E, ALA57E, ALA63E, ALA66E, ALA68E, ALA6D, ALA75D, ALA78D, ALA88E, ALA94D, ALA94E, ALA97D, ALA97E, ARG128D, ARG14E, ARG21E, ARG84D, ASN149D, ASN2D, ASN48E, ASN7D, ASN99D, ASN99E, ASP107D, ASP107E, ASP28E, ASP32E, ASP36E, ASP46E, ASP47E, GLN106D, GLN106E, GLN124D, GLN24E, GLU120D, GLU127D, GLU139D, GLU146D, GLU59E, GLU65E, GLU91D, GLU91E, GLY100D, GLY100E, GLY109D, GLY115D, GLY56E, GLY85E, GLY86E, GLY95D, GLY95E, GLY96D, GLY96E, HIS89D, HIS89E, ILE148D, ILE154D, ILE17E, ILE19E, ILE3D, ILE49E, ILE4D, ILE83D, LEU101D, LEU101E, LEU117D, LEU142D, LEU145D, LEU151D, LEU31E, LEU38E, LEU60E, LEU62E, LEU67E, LYS136D, LYS45E, LYS5D, LYS69E, LYS72E, MET147D, MET1D, PHE114D, PHE22E, PHE90D, PHE90E, PRO111D, PRO55E, PRO61E, SER103D, SER103E, SER108D, SER121D, SER70E, SER98D, THR118D, THR119D, THR143D, THR18E, THR39E, THR50E, THR64E, THR87E, TRP53E, TYR58E, TYR73E, TYR92D, TYR92E, VAL104D, VAL104E, VAL110D, VAL112D, VAL116D, VAL150D, VAL15E, VAL35E, VAL51E, VAL52E, VAL54E, VAL82D, VAL8D, VAL93D, VAL93E
• D-F: ALA125D, ALA125F, ALA129D, ALA133D, ALA138D, ALA34D, ALA37D, ARG128D, ARG21F, ARG40D, ARG84F, ASN135D, ASN23F, ASN27D, ASN27F, ASP28D, ASP28F, ASP32D, ASP36D, GLN124D, GLN24D, GLN24F, GLU120F, GLU123D, GLU123F, GLU127D, GLY130D, GLY134D, GLY33D, GLY85F, GLY86F, ILE122D, ILE122F, ILE126D, ILE126F, ILE26D, ILE26F, ILE41D, ILE83F, LEU30D, LEU31D, LYS132D, PHE22F, PHE25D, PHE25F, PHE90F, PRO55F, SER121F, SER29D, THR119F, THR131D, THR131F, THR39D, THR81F, THR87F, TRP53F, VAL54F, VAL82F
• D-J: ALA10D, ALA10J, ALA133D, ALA133J, ALA37D, ALA37J, ALA6D, ALA6J, ALA9D, ALA9J, ARG128D, ARG128J, ARG40D, ARG40J, ASN149D, ASN149J, ASN7D, ASN7J, ASP32D, ASP32J, ASP36D, ASP36J, GLN43D, GLN43J, GLU146D, GLU146J, GLY33D, GLY33J, GLY42D, GLY42J, ILE41D, ILE41J, ILE4D, ILE4J, LEU142D, LEU142J, LEU38D, LEU38J, LYS132D, LYS132J, LYS5D, LYS5J, PRO11D, PRO11J, THR143D, THR143J, THR39D, THR39J, VAL150D, VAL150J, VAL35D, VAL35J, VAL44D, VAL44J, VAL8D, VAL8J
• D-R: ALA125D, ALA125R, ALA129R, ALA133R, ALA138R, ALA34R, ALA37R, ARG128R, ARG21D, ARG40R, ARG84D, ASN135R, ASN23D, ASN27D, ASN27R, ASP28D, ASP28R, ASP32R, ASP36R, GLN124R, GLN24D, GLN24R, GLU120D, GLU123D, GLU123R, GLU127R, GLY130R, GLY134R, GLY33R, GLY85D, GLY86D, ILE122D, ILE122R, ILE126D, ILE126R, ILE26D, ILE26R, ILE41R, ILE83D, LEU30R, LEU31R, LYS132R, PHE22D, PHE25D, PHE25R, PHE90D, PRO55D, SER121D, SER29R, THR131D, THR131R, THR81D, THR87D, TRP53D, VAL54D, VAL82D
• E-J: ALA125E, ALA125J, ALA129J, ALA133J, ALA138J, ALA34J, ALA37J, ARG128J, ARG21E, ARG40J, ARG84E, ASN135J, ASN23E, ASN27E, ASN27J, ASP28E, ASP28J, ASP32J, ASP36J, GLN124J, GLN24E, GLN24J, GLU120E, GLU123E, GLU123J, GLU127J, GLY130J, GLY134J, GLY33J, GLY85E, GLY86E, ILE122E, ILE122J, ILE126E, ILE126J, ILE26E, ILE26J, ILE41J, ILE83E, LEU30J, LEU31J, LYS132J, PHE22E, PHE25E, PHE25J, PHE90E, PRO55E, SER121E, SER29J, THR131E, THR131J, THR81E, THR87E, TRP53E, VAL54E, VAL82E
• E-N: ALA10E, ALA10N, ALA133E, ALA133N, ALA37E, ALA37N, ALA6E, ALA6N, ALA9E, ALA9N, ARG128E, ARG128N, ARG40E, ARG40N, ASN149E, ASN149N, ASN7E, ASN7N, ASP32E, ASP32N, ASP36E, ASP36N, GLN43E, GLN43N, GLU146E, GLU146N, GLY33E, GLY33N, GLY42E, GLY42N, ILE41E, ILE41N, ILE4E, ILE4N, LEU142E, LEU142N, LEU38E, LEU38N, LYS132E, LYS132N, LYS5E, LYS5N, PRO11E, PRO11N, THR143E, THR143N, THR39E, THR39N, VAL150E, VAL150N, VAL35E, VAL35N, VAL44E, VAL44N, VAL8E, VAL8N
• E-O: ALA125E, ALA125O, ALA129E, ALA133E, ALA138E, ALA34E, ALA37E, ARG128E, ARG21O, ARG40E, ARG84O, ASN135E, ASN23O, ASN27E, ASN27O, ASP28E, ASP28O, ASP32E, ASP36E, GLN124E, GLN24E, GLN24O, GLU120O, GLU123E, GLU123O, GLU127E, GLY130E, GLY134E, GLY33E, GLY85O, GLY86O, ILE122E, ILE122O, ILE126E, ILE126O, ILE26E, ILE26O, ILE41E, ILE83O, LEU30E, LEU31E, LYS132E, PHE22O, PHE25E, PHE25O, PHE90O, PRO55O, SER121O, SER29E, SER29O, THR131E, THR131O, THR81O, THR87O, TRP53O, VAL54O, VAL82O
• F-G: ALA102F, ALA105F, ALA113F, ALA125F, ALA133F, ALA140F, ALA144F, ALA153F, ALA16G, ALA57G, ALA63G, ALA66G, ALA68G, ALA6F, ALA75F, ALA78F, ALA88G, ALA94F, ALA97F, ALA97G, ARG128F, ARG14G, ARG21G, ARG84F, ASN2F, ASN48G, ASN7F, ASN99F, ASN99G, ASP107F, ASP107G, ASP28G, ASP32G, ASP36G, ASP46G, ASP47G, GLN106F, GLN106G, GLN124F, GLN24G, GLU120F, GLU127F, GLU139F, GLU146F, GLU59G, GLU65G, GLU91F, GLU91G, GLY100F, GLY100G, GLY109F, GLY115F, GLY56G, GLY85G, GLY86G, GLY95F, GLY95G, GLY96F, GLY96G, HIS89G, ILE148F, ILE154F, ILE17G, ILE19G, ILE3F, ILE49G, ILE4F, ILE83F, LEU101F, LEU101G, LEU117F, LEU142F, LEU145F, LEU151F, LEU31G, LEU38G, LEU60G, LEU62G, LEU67G, LYS136F, LYS45G, LYS5F, LYS69G, LYS72G, MET147F, MET1F, PHE114F, PHE22G, PHE90F, PHE90G, PRO111F, PRO55G, PRO61G, SER103F, SER103G, SER108F, SER121F, SER70G, SER98F, THR118F, THR119F, THR143F, THR18G, THR39G, THR50G, THR64G, THR87G, TRP53G, TYR58G, TYR73G, TYR92F, TYR92G, VAL104F, VAL104G, VAL110F, VAL112F, VAL116F, VAL150F, VAL15G, VAL35G, VAL51G, VAL52G, VAL54G, VAL82F, VAL8F, VAL93F, VAL93G
• F-J: ALA102J, ALA105J, ALA113J, ALA125J, ALA140J, ALA144J, ALA153J, ALA16F, ALA57F, ALA63F, ALA66F, ALA68F, ALA6J, ALA75J, ALA78J, ALA88F, ALA94J, ALA97F, ALA97J, ARG128J, ARG14F, ARG21F, ARG84J, ASN2J, ASN48F, ASN7J, ASN99F, ASN99J, ASP107F, ASP107J, ASP28F, ASP32F, ASP36F, ASP46F, ASP47F, ASP74J, GLN106F, GLN106J, GLN124J, GLN24F, GLU120J, GLU127J, GLU139J, GLU146J, GLU59F, GLU65F, GLU91F, GLU91J, GLY100F, GLY100J, GLY109J, GLY115J, GLY56F, GLY85F, GLY86F, GLY95F, GLY95J, GLY96F, GLY96J, HIS89F, ILE148J, ILE154J, ILE17F, ILE19F, ILE3J, ILE49F, ILE4J, ILE83J, LEU101F, LEU101J, LEU117J, LEU142J, LEU145J, LEU151J, LEU31F, LEU38F, LEU60F, LEU62F, LEU67F, LYS136J, LYS45F, LYS5J, LYS69F, LYS72F, MET147J, MET1J, PHE114J, PHE22F, PHE90F, PHE90J, PRO111J, PRO55F, PRO61F, SER103F, SER103J, SER108J, SER121J, SER70F, SER98J, THR118J, THR119J, THR143J, THR18F, THR39F, THR50F, THR64F, THR87F, TRP53F, TYR58F, TYR73F, TYR92F, TYR92J, VAL104F, VAL104J, VAL110J, VAL112J, VAL116J, VAL150J, VAL15F, VAL35F, VAL51F, VAL52F, VAL54F, VAL82J, VAL8J, VAL93F, VAL93J
• F-Q: ALA10F, ALA10Q, ALA133F, ALA133Q, ALA37F, ALA37Q, ALA6F, ALA6Q, ALA9F, ALA9Q, ARG128F, ARG128Q, ARG40F, ARG40Q, ASN149F, ASN149Q, ASN7F, ASN7Q, ASP32F, ASP32Q, ASP36F, ASP36Q, GLN43F, GLN43Q, GLU146F, GLU146Q, GLY33F, GLY33Q, GLY42F, GLY42Q, ILE41F, ILE41Q, ILE4F, ILE4Q, LEU142F, LEU142Q, LEU38F, LEU38Q, LYS132F, LYS132Q, LYS5F, LYS5Q, PRO11F, PRO11Q, THR143F, THR143Q, THR39F, THR39Q, VAL150F, VAL150Q, VAL35F, VAL44F, VAL44Q, VAL8F, VAL8Q
• F-R: ALA125F, ALA125R, ALA129F, ALA133F, ALA138F, ALA34F, ALA37F, ARG128F, ARG21R, ARG40F, ARG84R, ASN135F, ASN23R, ASN27F, ASN27R, ASP28F, ASP28R, ASP32F, ASP36F, GLN124F, GLN24F, GLN24R, GLU120R, GLU123F, GLU123R, GLU127F, GLY130F, GLY134F, GLY33F, GLY85R, GLY86R, ILE122F, ILE122R, ILE126F, ILE126R, ILE26F, ILE26R, ILE41F, ILE83R, LEU30F, LEU31F, LYS132F, PHE22R, PHE25F, PHE25R, PHE90R, PRO55R, SER121R, SER29F, THR131F, THR131R, THR39F, THR81R, THR87R, TRP53R, VAL54R, VAL82R
• G-H: ALA102G, ALA105G, ALA113G, ALA125G, ALA140G, ALA144G, ALA153G, ALA16H, ALA20H, ALA57H, ALA63H, ALA66H, ALA68H, ALA6G, ALA75G, ALA78G, ALA88H, ALA94G, ALA97G, ALA97H, ARG128G, ARG14H, ARG21H, ARG84G, ASN2G, ASN48H, ASN7G, ASN99G, ASN99H, ASP107G, ASP107H, ASP28H, ASP32H, ASP36H, ASP46H, ASP47H, GLN106G, GLN106H, GLN124G, GLN24H, GLU120G, GLU127G, GLU139G, GLU146G, GLU59H, GLU65H, GLU91G, GLU91H, GLY100G, GLY100H, GLY109G, GLY115G, GLY56H, GLY85H, GLY86H, GLY95G, GLY95H, GLY96G, GLY96H, HIS89H, ILE148G, ILE154G, ILE17H, ILE19H, ILE3G, ILE49H, ILE4G, ILE83G, LEU101G, LEU101H, LEU117G, LEU142G, LEU145G, LEU151G, LEU31H, LEU38H, LEU60H, LEU62H, LEU67H, LYS136G, LYS45H, LYS5G, LYS69H, LYS72H, MET147G, MET1G, PHE114G, PHE22H, PHE90G, PHE90H, PRO111G, PRO55H, PRO61H, SER103G, SER103H, SER108G, SER121G, SER70H, SER98G, THR118G, THR119G, THR143G, THR18H, THR39H, THR50H, THR64H, THR87H, TRP53H, TYR58H, TYR73H, TYR92G, TYR92H, VAL104G, VAL104H, VAL110G, VAL112G, VAL116G, VAL150G, VAL15H, VAL35H, VAL51H, VAL52H, VAL54H, VAL82G, VAL8G, VAL93G, VAL93H
• G-Q: ALA125G, ALA125Q, ALA129Q, ALA133Q, ALA138Q, ALA34Q, ALA37Q, ARG128Q, ARG21G, ARG40Q, ARG84G, ASN135Q, ASN23G, ASN27G, ASN27Q, ASP28G, ASP28Q, ASP32Q, ASP36Q, GLN124Q, GLN24G, GLN24Q, GLU120G, GLU123G, GLU123Q, GLU127Q, GLY130Q, GLY134Q, GLY33Q, GLY85G, GLY86G, ILE122G, ILE122Q, ILE126G, ILE126Q, ILE26G, ILE26Q, ILE41Q, ILE83G, LEU30Q, LEU31Q, LYS132Q, PHE22G, PHE25G, PHE25Q, PHE90G, PRO55G, SER121G, SER29Q, THR119G, THR131G, THR131Q, THR81G, THR87G, TRP53G, VAL54G, VAL82G
• G-f: ALA10G, ALA10f, ALA133G, ALA133f, ALA37G, ALA37f, ALA6G, ALA6f, ALA9G, ALA9f, ARG40G, ARG40f, ASN149G, ASN149f, ASN7G, ASN7f, ASP32G, ASP32f, ASP36G, ASP36f, GLN43G, GLN43f, GLU146G, GLU146f, GLY33G, GLY33f, GLY42G, GLY42f, ILE41G, ILE41f, ILE4G, ILE4f, LEU142G, LEU142f, LEU38G, LEU38f, LYS132G, LYS132f, LYS5G, LYS5f, PRO11G, PRO11f, THR143G, THR143f, THR39G, THR39f, VAL150G, VAL150f, VAL35G, VAL8G, VAL8f
• G-g: ALA125G, ALA125g, ALA129G, ALA133G, ALA138G, ALA34G, ALA37G, ARG128G, ARG21g, ARG40G, ARG84g, ASN135G, ASN23g, ASN27G, ASN27g, ASP28G, ASP28g, ASP32G, ASP36G, GLN124G, GLN24G, GLN24g, GLU120g, GLU123G, GLU123g, GLU127G, GLY130G, GLY134G, GLY33G, GLY85g, GLY86g, ILE122G, ILE122g, ILE126G, ILE126g, ILE26G, ILE26g, ILE41G, ILE83g, LEU30G, LEU31G, LYS132G, PHE22g, PHE25G, PHE25g, PHE90g, PRO55g, SER121g, SER29G, SER29g, THR119g, THR131G, THR131g, THR81g, THR87g, TRP53g, VAL54g, VAL82g
• H-I: ALA102H, ALA102I, ALA105H, ALA113H, ALA125H, ALA133H, ALA140H, ALA144H, ALA153H, ALA16I, ALA57I, ALA63I, ALA66I, ALA68I, ALA6H, ALA75H, ALA78H, ALA88I, ALA94H, ALA94I, ALA97H, ALA97I, ARG128H, ARG14I, ARG21I, ARG84H, ASN2H, ASN48I, ASN7H, ASN99H, ASN99I, ASP107H, ASP107I, ASP28I, ASP32I, ASP36I, ASP46I, ASP47I, ASP74H, GLN106H, GLN106I, GLN124H, GLN24I, GLU120H, GLU127H, GLU139H, GLU146H, GLU59I, GLU65I, GLU91H, GLU91I, GLY100H, GLY100I, GLY109H, GLY115H, GLY56I, GLY85I, GLY86I, GLY95H, GLY95I, GLY96H, GLY96I, HIS89I, ILE148H, ILE154H, ILE17I, ILE19I, ILE3H, ILE49I, ILE4H, ILE83H, LEU101H, LEU101I, LEU117H, LEU142H, LEU145H, LEU151H, LEU31I, LEU38I, LEU60I, LEU62I, LEU67I, LYS136H, LYS45I, LYS5H, LYS69I, LYS72I, MET147H, MET1H, PHE114H, PHE22I, PHE90H, PHE90I, PRO111H, PRO55I, PRO61I, SER103H, SER103I, SER108H, SER121H, SER70I, SER98H, THR118H, THR119H, THR143H, THR18I, THR39I, THR50I, THR64I, THR87I, TRP53I, TYR58I, TYR73I, TYR92H, TYR92I, VAL104H, VAL104I, VAL110H, VAL112H, VAL116H, VAL150H, VAL15I, VAL35I, VAL51I, VAL52I, VAL54I, VAL82H, VAL8H, VAL93H, VAL93I
• H-c: ALA133H, ALA133c, ALA37H, ALA37c, ALA6H, ALA6c, ALA9H, ALA9c, ARG128H, ARG128c, ARG40H, ARG40c, ASN149H, ASN7H, ASN7c, ASP32H, ASP32c, ASP36H, ASP36c, GLN43H, GLN43c, GLU146H, GLU146c, GLY33H, GLY33c, GLY42H, GLY42c, ILE41H, ILE41c, ILE4H, ILE4c, LEU142H, LEU142c, LEU38H, LEU38c, LYS132H, LYS132c, LYS5H, LYS5c, PRO11H, PRO11c, THR143H, THR143c, THR39H, THR39c, VAL150H, VAL150c, VAL8H, VAL8c
• H-d: ALA125H, ALA125d, ALA129H, ALA133H, ALA138H, ALA34H, ALA37H, ARG128H, ARG21d, ARG40H, ARG84d, ASN135H, ASN23d, ASN27H, ASN27d, ASP28H, ASP28d, ASP32H, ASP36H, GLN124H, GLN24H, GLN24d, GLU120d, GLU123H, GLU123d, GLU127H, GLY130H, GLY134H, GLY33H, GLY85d, GLY86d, ILE122H, ILE122d, ILE126H, ILE126d, ILE26H, ILE26d, ILE41H, ILE83d, LEU30H, LEU31H, LYS132H, PHE22d, PHE25H, PHE25d, PHE90d, PRO55d, SER121d, SER29H, THR119d, THR131H, THR131d, THR81d, THR87d, TRP53d, VAL54d, VAL82d
• H-f: ALA125H, ALA125f, ALA129f, ALA133f, ALA138f, ALA34f, ALA37f, ARG128f, ARG21H, ARG40f, ARG84H, ASN135f, ASN23H, ASN27H, ASN27f, ASP28H, ASP28f, ASP32f, ASP36f, GLN124f, GLN24H, GLN24f, GLU120H, GLU123H, GLU123f, GLU127f, GLY130f, GLY134f, GLY33f, GLY85H, GLY86H, ILE122H, ILE122f, ILE126H, ILE126f, ILE26H, ILE26f, ILE41f, ILE83H, LEU30f, LEU31f, LYS132f, PHE22H, PHE25H, PHE25f, PHE90H, PRO55H, SER121H, SER29f, THR119H, THR131H, THR131f, THR81H, THR87H, TRP53H, VAL54H, VAL82H
• I-J: ALA102I, ALA105I, ALA113I, ALA125I, ALA140I, ALA144I, ALA153I, ALA16J, ALA57J, ALA63J, ALA66J, ALA68J, ALA6I, ALA75I, ALA78I, ALA88J, ALA94I, ALA97I, ALA97J, ARG128I, ARG14J, ARG21J, ARG84I, ASN2I, ASN48J, ASN7I, ASN99I, ASN99J, ASP107I, ASP107J, ASP28J, ASP32J, ASP36J, ASP46J, ASP47J, GLN106I, GLN106J, GLN124I, GLN24J, GLU120I, GLU127I, GLU139I, GLU146I, GLU59J, GLU65J, GLU91I, GLU91J, GLY100I, GLY100J, GLY109I, GLY115I, GLY56J, GLY85J, GLY86J, GLY95I, GLY95J, GLY96I, GLY96J, HIS89J, ILE148I, ILE154I, ILE17J, ILE19J, ILE3I, ILE49J, ILE4I, ILE83I, LEU101I, LEU101J, LEU117I, LEU142I, LEU145I, LEU151I, LEU31J, LEU38J, LEU60J, LEU62J, LEU67J, LYS136I, LYS45J, LYS5I, LYS69J, LYS72J, MET147I, MET1I, PHE114I, PHE22J, PHE90I, PHE90J, PRO111I, PRO55J, PRO61J, SER103I, SER103J, SER108I, SER121I, SER70J, SER98I, THR118I, THR119I, THR143I, THR18J, THR39J, THR50J, THR64J, THR87J, TRP53J, TYR58J, TYR73J, TYR92I, TYR92J, VAL104I, VAL104J, VAL110I, VAL112I, VAL116I, VAL150I, VAL15J, VAL35J, VAL51J, VAL52J, VAL54J, VAL82I, VAL8I, VAL93I, VAL93J
• I-K: ALA125I, ALA125K, ALA129I, ALA133I, ALA138I, ALA34I, ALA37I, ARG128I, ARG21K, ARG40I, ARG84K, ASN135I, ASN23K, ASN27I, ASN27K, ASP28I, ASP28K, ASP32I, ASP36I, GLN124I, GLN24I, GLN24K, GLU120K, GLU123I, GLU123K, GLU127I, GLY130I, GLY134I, GLY33I, GLY85K, GLY86K, ILE122I, ILE122K, ILE126I, ILE126K, ILE26I, ILE26K, ILE41I, ILE83K, LEU30I, LEU31I, LYS132I, PHE22K, PHE25I, PHE25K, PHE90K, PRO55K, SER121K, SER29I, THR131I, THR131K, THR81K, THR87K, TRP53K, VAL54K, VAL82K
• I-O: ALA10I, ALA10O, ALA133I, ALA133O, ALA37I, ALA37O, ALA6I, ALA6O, ALA9I, ALA9O, ARG128I, ARG128O, ARG40I, ARG40O, ASN149I, ASN149O, ASN7I, ASN7O, ASP32I, ASP32O, ASP36I, ASP36O, GLN43I, GLN43O, GLU146I, GLU146O, GLY33I, GLY33O, GLY42I, GLY42O, ILE41I, ILE41O, ILE4I, ILE4O, LEU142I, LEU142O, LEU38I, LEU38O, LYS132I, LYS132O, LYS5I, LYS5O, PRO11I, PRO11O, THR143I, THR143O, THR39I, THR39O, VAL150I, VAL150O, VAL35O, VAL44I, VAL44O, VAL8I, VAL8O
• I-c: ALA125I, ALA125c, ALA129c, ALA133c, ALA138c, ALA34c, ALA37c, ARG128c, ARG21I, ARG40c, ARG84I, ASN135c, ASN23I, ASN27I, ASN27c, ASP28I, ASP28c, ASP32c, ASP36c, GLN124c, GLN24I, GLN24c, GLU120I, GLU123I, GLU123c, GLU127c, GLY130c, GLY134c, GLY33c, GLY85I, GLY86I, ILE122I, ILE122c, ILE126I, ILE126c, ILE26I, ILE26c, ILE41c, ILE83I, LEU30c, LEU31c, LYS132c, PHE22I, PHE25I, PHE25c, PHE90I, PRO55I, SER121I, SER29c, THR131I, THR131c, THR81I, THR87I, TRP53I, VAL54I, VAL82I
• J-O: ALA125J, ALA125O, ALA129O, ALA133O, ALA138O, ALA34O, ALA37O, ARG128O, ARG21J, ARG40O, ARG84J, ASN135O, ASN23J, ASN27J, ASN27O, ASP28J, ASP28O, ASP32O, ASP36O, GLN124O, GLN24J, GLN24O, GLU120J, GLU123J, GLU123O, GLU127O, GLY130O, GLY134O, GLY33O, GLY85J, GLY86J, ILE122J, ILE122O, ILE126J, ILE126O, ILE26J, ILE26O, ILE41O, ILE83J, LEU30O, LEU31O, LYS132O, PHE22J, PHE25J, PHE25O, PHE90J, PRO55J, SER121J, SER29O, THR119J, THR131J, THR131O, THR39O, THR81J, THR87J, TRP53J, VAL54J, VAL82J
• K-L: ALA102K, ALA102L, ALA105K, ALA113K, ALA125K, ALA140K, ALA144K, ALA153K, ALA16L, ALA57L, ALA63L, ALA66L, ALA68L, ALA6K, ALA75K, ALA78K, ALA88L, ALA94K, ALA94L, ALA97K, ALA97L, ARG128K, ARG14L, ARG21L, ARG84K, ASN2K, ASN48L, ASN7K, ASN99K, ASN99L, ASP107K, ASP107L, ASP28L, ASP32L, ASP36L, ASP46L, ASP47L, ASP74K, GLN106K, GLN106L, GLN124K, GLN24L, GLU120K, GLU127K, GLU139K, GLU146K, GLU59L, GLU65L, GLU91K, GLU91L, GLY100K, GLY100L, GLY109K, GLY115K, GLY56L, GLY85L, GLY86L, GLY95K, GLY95L, GLY96K, GLY96L, HIS89L, ILE148K, ILE154K, ILE17L, ILE19L, ILE3K, ILE49L, ILE4K, ILE83K, LEU101K, LEU101L, LEU117K, LEU142K, LEU145K, LEU151K, LEU31L, LEU38L, LEU60L, LEU62L, LEU67L, LYS136K, LYS45L, LYS5K, LYS69L, LYS72L, MET147K, MET1K, PHE114K, PHE22L, PHE90K, PHE90L, PRO111K, PRO55L, PRO61L, SER103K, SER103L, SER108K, SER121K, SER70L, SER98K, THR118K, THR119K, THR143K, THR18L, THR39L, THR50L, THR64L, THR87L, TRP53L, TYR58L, TYR73L, TYR92K, TYR92L, VAL104K, VAL104L, VAL110K, VAL112K, VAL116K, VAL150K, VAL15L, VAL35L, VAL51L, VAL52L, VAL54L, VAL82K, VAL8K, VAL93K, VAL93L
• K-O: ALA102K, ALA102O, ALA105O, ALA113O, ALA125O, ALA140O, ALA144O, ALA153O, ALA16K, ALA57K, ALA63K, ALA66K, ALA68K, ALA6O, ALA75O, ALA78O, ALA88K, ALA94O, ALA97K, ALA97O, ARG128O, ARG14K, ARG21K, ARG84O, ASN149O, ASN2O, ASN48K, ASN7O, ASN99K, ASN99O, ASP107K, ASP107O, ASP28K, ASP32K, ASP36K, ASP46K, ASP47K, ASP74O, GLN106K, GLN106O, GLN124O, GLN24K, GLU120O, GLU127O, GLU139O, GLU146O, GLU59K, GLU65K, GLU91K, GLU91O, GLY100K, GLY100O, GLY109O, GLY115O, GLY56K, GLY85K, GLY86K, GLY95K, GLY95O, GLY96K, GLY96O, HIS89K, ILE148O, ILE154O, ILE17K, ILE19K, ILE3O, ILE49K, ILE4O, ILE83O, LEU101K, LEU101O, LEU117O, LEU142O, LEU145O, LEU151O, LEU31K, LEU38K, LEU60K, LEU62K, LEU67K, LYS136O, LYS45K, LYS5O, LYS69K, LYS72K, MET147O, MET1O, PHE114O, PHE22K, PHE90K, PHE90O, PRO111O, PRO55K, PRO61K, SER103K, SER103O, SER108O, SER121O, SER70K, SER98O, THR118O, THR119O, THR143O, THR18K, THR39K, THR50K, THR64K, THR87K, TRP53K, TYR58K, TYR73K, TYR92K, TYR92O, VAL104K, VAL104O, VAL110O, VAL112O, VAL116O, VAL150O, VAL15K, VAL35K, VAL51K, VAL52K, VAL54K, VAL82O, VAL8O, VAL93K, VAL93O
• K-b: ALA10K, ALA10b, ALA133K, ALA133b, ALA37K, ALA37b, ALA6K, ALA6b, ALA9K, ALA9b, ARG128K, ARG128b, ARG40K, ARG40b, ASN149K, ASN149b, ASN7K, ASN7b, ASP32K, ASP32b, ASP36K, ASP36b, GLN43K, GLN43b, GLU146K, GLU146b, GLY33K, GLY33b, GLY42K, GLY42b, ILE41K, ILE41b, ILE4K, ILE4b, LEU142K, LEU142b, LEU38K, LEU38b, LYS132K, LYS132b, LYS5K, LYS5b, PRO11K, PRO11b, THR143K, THR143b, THR39K, THR39b, VAL150K, VAL150b, VAL35b, VAL44K, VAL44b, VAL8K, VAL8b
• K-c: ALA125K, ALA125c, ALA129K, ALA133K, ALA138K, ALA34K, ALA37K, ARG128K, ARG21c, ARG40K, ARG84c, ASN135K, ASN23c, ASN27K, ASN27c, ASP28K, ASP28c, ASP32K, ASP36K, GLN124K, GLN24K, GLN24c, GLU120c, GLU123K, GLU123c, GLU127K, GLY130K, GLY134K, GLY33K, GLY85c, GLY86c, ILE122K, ILE122c, ILE126K, ILE126c, ILE26K, ILE26c, ILE41K, ILE83c, LEU30K, LEU31K, LYS132K, PHE22c, PHE25K, PHE25c, PHE90c, PRO55c, SER121c, SER29K, THR131K, THR131c, THR81c, THR87c, TRP53c, VAL54c, VAL82c
• L-M: ALA102L, ALA102M, ALA105L, ALA113L, ALA125L, ALA140L, ALA144L, ALA153L, ALA16M, ALA57M, ALA63M, ALA66M, ALA68M, ALA6L, ALA75L, ALA78L, ALA88M, ALA94L, ALA97L, ALA97M, ARG128L, ARG14M, ARG21M, ARG84L, ASN2L, ASN48M, ASN7L, ASN99L, ASN99M, ASP107L, ASP107M, ASP28M, ASP32M, ASP36M, ASP46M, ASP47M, ASP74L, GLN106L, GLN106M, GLN124L, GLN24M, GLU120L, GLU127L, GLU139L, GLU146L, GLU59M, GLU65M, GLU91L, GLU91M, GLY100L, GLY100M, GLY109L, GLY115L, GLY56M, GLY85M, GLY86M, GLY95L, GLY95M, GLY96L, GLY96M, HIS89M, ILE148L, ILE154L, ILE17M, ILE19M, ILE3L, ILE49M, ILE4L, ILE83L, LEU101L, LEU101M, LEU117L, LEU142L, LEU145L, LEU151L, LEU31M, LEU38M, LEU60M, LEU62M, LEU67M, LYS136L, LYS45M, LYS5L, LYS69M, LYS72M, MET147L, MET1L, PHE114L, PHE22M, PHE90L, PHE90M, PRO111L, PRO55M, PRO61M, SER103L, SER103M, SER108L, SER121L, SER70M, SER98L, THR118L, THR119L, THR143L, THR18M, THR39M, THR50M, THR64M, THR87M, TRP53M, TYR58M, TYR73M, TYR92L, TYR92M, VAL104L, VAL104M, VAL110L, VAL112L, VAL116L, VAL150L, VAL15M, VAL35M, VAL51M, VAL52M, VAL54M, VAL82L, VAL8L, VAL93L, VAL93M
• L-b: ALA125L, ALA125b, ALA129b, ALA133b, ALA138b, ALA34b, ALA37b, ARG128b, ARG21L, ARG40b, ARG84L, ASN135b, ASN23L, ASN27L, ASN27b, ASP28L, ASP28b, ASP32b, ASP36b, GLN124b, GLN24L, GLN24b, GLU120L, GLU123L, GLU123b, GLU127b, GLY130b, GLY134b, GLY33b, GLY85L, GLY86L, ILE122L, ILE122b, ILE126L, ILE126b, ILE26L, ILE26b, ILE41b, ILE83L, LEU30b, LEU31b, LYS132b, PHE22L, PHE25L, PHE25b, PHE90L, PRO55L, SER121L, SER29b, THR131L, THR131b, THR39b, THR81L, THR87L, TRP53L, VAL54L, VAL82L
• L-k: ALA6L, ALA6k, ARG40L, ARG40k, ASN7L, ASN7k, ASP36L, ASP36k, GLU146L, GLU146k, LYS5L, LYS5k
• L-l: ARG21l, ARG40L, ASP28L, ASP28l, ASP32L, ASP36L, GLU123L, GLU123l, GLY130L, PHE25l
• M-N: ALA102M, ALA105M, ALA113M, ALA125M, ALA133M, ALA140M, ALA144M, ALA153M, ALA16N, ALA57N, ALA63N, ALA66N, ALA68N, ALA6M, ALA75M, ALA78M, ALA88N, ALA94M, ALA97M, ALA97N, ARG128M, ARG14N, ARG21N, ARG84M, ASN2M, ASN48N, ASN7M, ASN99M, ASN99N, ASP107M, ASP107N, ASP28N, ASP32N, ASP36N, ASP46N, ASP47N, ASP74M, GLN106M, GLN106N, GLN124M, GLN24N, GLU120M, GLU127M, GLU139M, GLU146M, GLU59N, GLU65N, GLU91M, GLU91N, GLY100M, GLY100N, GLY109M, GLY115M, GLY56N, GLY85N, GLY86N, GLY95M, GLY95N, GLY96M, GLY96N, HIS89N, ILE148M, ILE154M, ILE17N, ILE19N, ILE3M, ILE49N, ILE4M, ILE83M, LEU101M, LEU101N, LEU117M, LEU142M, LEU145M, LEU151M, LEU31N, LEU38N, LEU60N, LEU62N, LEU67N, LYS136M, LYS45N, LYS5M, LYS69N, LYS72N, MET147M, MET1M, PHE114M, PHE22N, PHE90M, PHE90N, PRO111M, PRO55N, PRO61N, SER103M, SER103N, SER108M, SER121M, SER70N, SER98M, THR118M, THR119M, THR143M, THR18N, THR39N, THR50N, THR64N, THR87N, TRP53N, TYR58N, TYR73N, TYR92M, TYR92N, VAL104M, VAL104N, VAL110M, VAL112M, VAL116M, VAL150M, VAL15N, VAL35N, VAL51N, VAL52N, VAL54N, VAL82M, VAL8M, VAL93M, VAL93N
• M-k: ARG21M, ARG40k, ASP28M, ASP28k, ASP32k, ASP36k, GLU123M, GLU123k, GLY130k, PHE25M
• M-w: ALA6M, ALA6w, ARG40M, ARG40w, ASN7M, ASN7w, ASP36M, ASP36w, GLU146M, GLU146w, LYS5M, LYS5w
• M-x: ARG21x, ARG40M, ASP28M, ASP28x, ASP32M, ASP36M, GLU123M, GLU123x, GLY130M, PHE25x
• N-O: ALA102N, ALA105N, ALA113N, ALA125N, ALA140N, ALA144N, ALA153N, ALA16O, ALA57O, ALA63O, ALA66O, ALA68O, ALA6N, ALA75N, ALA78N, ALA88O, ALA94N, ALA97N, ALA97O, ARG128N, ARG14O, ARG21O, ARG84N, ASN2N, ASN48O, ASN7N, ASN99N, ASN99O, ASP107N, ASP107O, ASP28O, ASP32O, ASP36O, ASP46O, ASP47O, GLN106N, GLN106O, GLN124N, GLN24O, GLU120N, GLU127N, GLU139N, GLU146N, GLU59O, GLU65O, GLU91N, GLU91O, GLY100N, GLY100O, GLY109N, GLY115N, GLY56O, GLY85O, GLY86O, GLY95N, GLY95O, GLY96N, GLY96O, HIS89O, ILE148N, ILE154N, ILE17O, ILE19O, ILE3N, ILE49O, ILE4N, ILE83N, LEU101N, LEU101O, LEU117N, LEU142N, LEU145N, LEU151N, LEU31O, LEU38O, LEU60O, LEU62O, LEU67O, LYS136N, LYS45O, LYS5N, LYS69O, LYS72O, MET147N, MET1N, PHE114N, PHE22O, PHE90N, PHE90O, PRO111N, PRO55O, PRO61O, SER103N, SER103O, SER108N, SER121N, SER70O, SER98N, THR118N, THR119N, THR143N, THR18O, THR39O, THR50O, THR64O, THR87O, TRP53O, TYR58O, TYR73O, TYR92N, TYR92O, VAL104N, VAL104O, VAL110N, VAL112N, VAL116N, VAL150N, VAL15O, VAL35O, VAL51O, VAL52O, VAL54O, VAL82N, VAL8N, VAL93N, VAL93O
• N-w: ARG21N, ARG40w, ASP28N, ASP28w, ASP32w, ASP36w, GLU123N, GLU123w, GLY130w, PHE25N
• P-Q: ALA102P, ALA105P, ALA113P, ALA125P, ALA140P, ALA144P, ALA153P, ALA16Q, ALA57Q, ALA63Q, ALA66Q, ALA68Q, ALA6P, ALA75P, ALA78P, ALA88Q, ALA94P, ALA97P, ALA97Q, ARG128P, ARG14Q, ARG21Q, ARG84P, ASN2P, ASN48Q, ASN7P, ASN99P, ASN99Q, ASP107P, ASP107Q, ASP28Q, ASP32Q, ASP36Q, ASP46Q, ASP47Q, GLN106P, GLN106Q, GLN124P, GLN24Q, GLU120P, GLU127P, GLU139P, GLU146P, GLU59Q, GLU65Q, GLU91P, GLU91Q, GLY100P, GLY100Q, GLY109P, GLY115P, GLY56Q, GLY85Q, GLY86Q, GLY95P, GLY95Q, GLY96P, GLY96Q, HIS89Q, ILE148P, ILE154P, ILE17Q, ILE19Q, ILE3P, ILE49Q, ILE4P, ILE83P, LEU101P, LEU101Q, LEU117P, LEU142P, LEU145P, LEU151P, LEU31Q, LEU38Q, LEU60Q, LEU62Q, LEU67Q, LYS136P, LYS45Q, LYS5P, LYS69Q, LYS72Q, MET147P, MET1P, PHE114P, PHE22Q, PHE90P, PHE90Q, PRO111P, PRO55Q, PRO61Q, SER103P, SER103Q, SER108P, SER121P, SER70Q, SER98P, THR118P, THR119P, THR143P, THR18Q, THR39Q, THR50Q, THR64Q, THR87Q, TRP53Q, TYR58Q, TYR73Q, TYR92P, TYR92Q, VAL104P, VAL104Q, VAL110P, VAL112P, VAL116P, VAL150P, VAL15Q, VAL35Q, VAL51Q, VAL52Q, VAL54Q, VAL82P, VAL8P, VAL93P, VAL93Q
• P-T: ALA102T, ALA105T, ALA113T, ALA125T, ALA133T, ALA140T, ALA144T, ALA153T, ALA16P, ALA57P, ALA63P, ALA66P, ALA68P, ALA6T, ALA75T, ALA78T, ALA88P, ALA94T, ALA97P, ALA97T, ARG128T, ARG14P, ARG21P, ARG84T, ASN2T, ASN48P, ASN7T, ASN99P, ASN99T, ASP107P, ASP107T, ASP28P, ASP32P, ASP36P, ASP46P, ASP47P, GLN106P, GLN106T, GLN124T, GLN24P, GLU120T, GLU127T, GLU139T, GLU146T, GLU59P, GLU65P, GLU91P, GLU91T, GLY100P, GLY100T, GLY109T, GLY115T, GLY56P, GLY85P, GLY86P, GLY95P, GLY95T, GLY96P, GLY96T, HIS89P, ILE148T, ILE154T, ILE17P, ILE19P, ILE3T, ILE49P, ILE4T, ILE83T, LEU101P, LEU101T, LEU117T, LEU142T, LEU145T, LEU151T, LEU31P, LEU38P, LEU60P, LEU62P, LEU67P, LYS136T, LYS45P, LYS5T, LYS69P, LYS72P, MET147T, MET1T, PHE114T, PHE22P, PHE90P, PHE90T, PRO111T, PRO55P, PRO61P, SER103P, SER103T, SER108T, SER121T, SER70P, SER98T, THR118T, THR119T, THR143T, THR18P, THR39P, THR50P, THR64P, THR87P, TRP53P, TYR58P, TYR73P, TYR92P, TYR92T, VAL104P, VAL104T, VAL110T, VAL112T, VAL116T, VAL150T, VAL15P, VAL35P, VAL51P, VAL52P, VAL54P, VAL82T, VAL8T, VAL93P, VAL93T
• P-3: ALA1253, ALA125P, ALA1293, ALA1333, ALA1383, ALA343, ALA373, ARG1283, ARG21P, ARG403, ARG84P, ASN1353, ASN23P, ASN273, ASN27P, ASP283, ASP28P, ASP323, ASP363, GLN1243, GLN243, GLN24P, GLU120P, GLU1233, GLU123P, GLU1273, GLY1303, GLY1343, GLY333, GLY85P, GLY86P, ILE1223, ILE122P, ILE1263, ILE126P, ILE263, ILE26P, ILE413, ILE83P, LEU303, LEU313, LYS1323, PHE22P, PHE253, PHE25P, PHE90P, PRO55P, SER121P, SER293, SER29P, THR1313, THR131P, THR393, THR81P, THR87P, TRP53P, VAL54P, VAL82P
• P-g: ALA10P, ALA10g, ALA133P, ALA133g, ALA37P, ALA37g, ALA6P, ALA6g, ALA9P, ALA9g, ARG128P, ARG128g, ARG40P, ARG40g, ASN149P, ASN149g, ASN7P, ASN7g, ASP32P, ASP32g, ASP36P, ASP36g, GLN43P, GLN43g, GLU146P, GLU146g, GLY33P, GLY33g, GLY42P, GLY42g, ILE41P, ILE41g, ILE4P, ILE4g, LEU142P, LEU142g, LEU38P, LEU38g, LYS132P, LYS132g, LYS5P, LYS5g, PRO11P, PRO11g, THR143P, THR143g, THR39P, THR39g, VAL150P, VAL150g, VAL44g, VAL8P, VAL8g
• P-h: ALA125P, ALA125h, ALA129P, ALA133P, ALA138P, ALA34P, ALA37P, ARG128P, ARG21h, ARG40P, ARG84h, ASN135P, ASN23h, ASN27P, ASN27h, ASP28P, ASP28h, ASP32P, ASP36P, GLN124P, GLN24P, GLN24h, GLU120h, GLU123P, GLU123h, GLU127P, GLY130P, GLY134P, GLY33P, GLY85h, GLY86h, ILE122P, ILE122h, ILE126P, ILE126h, ILE26P, ILE26h, ILE41P, ILE83h, LEU30P, LEU31P, LYS132P, PHE22h, PHE25P, PHE25h, PRO55h, SER121h, SER29P, THR119h, THR131P, THR131h, THR81h, THR87h, TRP53h, VAL54h
• Q-R: ALA102Q, ALA102R, ALA105Q, ALA113Q, ALA125Q, ALA140Q, ALA144Q, ALA153Q, ALA16R, ALA57R, ALA63R, ALA66R, ALA68R, ALA6Q, ALA75Q, ALA78Q, ALA88R, ALA94Q, ALA94R, ALA97Q, ALA97R, ARG128Q, ARG14R, ARG21R, ARG84Q, ASN2Q, ASN48R, ASN7Q, ASN99Q, ASN99R, ASP107Q, ASP107R, ASP28R, ASP32R, ASP36R, ASP46R, ASP47R, ASP74Q, GLN106Q, GLN106R, GLN124Q, GLN24R, GLU120Q, GLU127Q, GLU139Q, GLU146Q, GLU59R, GLU65R, GLU91Q, GLU91R, GLY100Q, GLY100R, GLY109Q, GLY115Q, GLY56R, GLY85R, GLY86R, GLY95Q, GLY95R, GLY96Q, GLY96R, HIS89Q, HIS89R, ILE148Q, ILE154Q, ILE17R, ILE19R, ILE3Q, ILE49R, ILE4Q, ILE83Q, LEU101Q, LEU101R, LEU117Q, LEU142Q, LEU145Q, LEU151Q, LEU31R, LEU38R, LEU60R, LEU62R, LEU67R, LYS136Q, LYS45R, LYS5Q, LYS69R, LYS72R, MET147Q, MET1Q, PHE114Q, PHE22R, PHE90Q, PHE90R, PRO111Q, PRO55R, PRO61R, SER103Q, SER103R, SER108Q, SER121Q, SER70R, SER98Q, THR118Q, THR119Q, THR143Q, THR18R, THR39R, THR50R, THR64R, THR87R, TRP53R, TYR58R, TYR73R, TYR92Q, TYR92R, VAL104Q, VAL104R, VAL110Q, VAL112Q, VAL116Q, VAL150Q, VAL15R, VAL35R, VAL51R, VAL52R, VAL54R, VAL82Q, VAL8Q, VAL93Q, VAL93R
• Q-g: ALA125Q, ALA125g, ALA129g, ALA133g, ALA138g, ALA34g, ALA37g, ARG128g, ARG21Q, ARG40g, ARG84Q, ASN135g, ASN23Q, ASN27Q, ASN27g, ASP28Q, ASP28g, ASP32g, ASP36g, GLN124g, GLN24Q, GLN24g, GLU120Q, GLU123Q, GLU123g, GLU127g, GLY130g, GLY134g, GLY33g, GLY85Q, GLY86Q, ILE122Q, ILE122g, ILE126Q, ILE126g, ILE26Q, ILE26g, ILE41g, ILE83Q, LEU30g, LEU31g, LYS132g, PHE22Q, PHE25Q, PHE25g, PHE90Q, PRO55Q, SER121Q, SER29g, THR131Q, THR131g, THR39g, THR81Q, THR87Q, TRP53Q, VAL54Q, VAL82Q
• R-S: ALA102R, ALA105R, ALA113R, ALA125R, ALA140R, ALA144R, ALA153R, ALA16S, ALA57S, ALA63S, ALA66S, ALA68S, ALA6R, ALA75R, ALA78R, ALA88S, ALA94R, ALA94S, ALA97R, ALA97S, ARG128R, ARG14S, ARG21S, ARG84R, ASN2R, ASN48S, ASN7R, ASN99R, ASN99S, ASP107R, ASP107S, ASP28S, ASP32S, ASP36S, ASP46S, ASP47S, GLN106R, GLN106S, GLN124R, GLN24S, GLU120R, GLU127R, GLU139R, GLU146R, GLU59S, GLU65S, GLU91R, GLU91S, GLY100R, GLY100S, GLY109R, GLY115R, GLY56S, GLY85S, GLY86S, GLY95R, GLY95S, GLY96R, GLY96S, HIS89R, HIS89S, ILE148R, ILE154R, ILE17S, ILE19S, ILE3R, ILE49S, ILE4R, ILE83R, LEU101R, LEU101S, LEU117R, LEU142R, LEU145R, LEU151R, LEU31S, LEU38S, LEU60S, LEU62S, LEU67S, LYS136R, LYS45S, LYS5R, LYS69S, LYS72S, MET147R, MET1R, PHE114R, PHE22S, PHE90R, PHE90S, PRO111R, PRO55S, PRO61S, SER103R, SER103S, SER108R, SER121R, SER70S, SER98R, THR118R, THR119R, THR143R, THR18S, THR39S, THR50S, THR64S, THR87S, TRP53S, TYR58S, TYR73S, TYR92R, TYR92S, VAL104R, VAL104S, VAL110R, VAL112R, VAL116R, VAL150R, VAL15S, VAL35S, VAL51S, VAL52S, VAL54S, VAL82R, VAL8R, VAL93R, VAL93S
• S-T: ALA102S, ALA102T, ALA105S, ALA113S, ALA125S, ALA140S, ALA144S, ALA153S, ALA16T, ALA20T, ALA57T, ALA63T, ALA66T, ALA68T, ALA6S, ALA75S, ALA78S, ALA88T, ALA94S, ALA97S, ALA97T, ARG128S, ARG14T, ARG21T, ARG84S, ASN2S, ASN48T, ASN7S, ASN99S, ASN99T, ASP107S, ASP107T, ASP28T, ASP32T, ASP36T, ASP46T, ASP47T, ASP74S, GLN106S, GLN106T, GLN124S, GLN24T, GLU120S, GLU127S, GLU139S, GLU146S, GLU59T, GLU65T, GLU91S, GLU91T, GLY100S, GLY100T, GLY109S, GLY115S, GLY56T, GLY85T, GLY86T, GLY95S, GLY95T, GLY96S, GLY96T, HIS89T, ILE148S, ILE154S, ILE17T, ILE19T, ILE3S, ILE49T, ILE4S, ILE83S, LEU101S, LEU101T, LEU117S, LEU142S, LEU145S, LEU151S, LEU31T, LEU38T, LEU60T, LEU62T, LEU67T, LYS136S, LYS45T, LYS5S, LYS69T, LYS72T, MET147S, MET1S, PHE114S, PHE22T, PHE90S, PHE90T, PRO111S, PRO55T, PRO61T, SER103S, SER103T, SER108S, SER121S, SER70T, SER98S, THR118S, THR119S, THR143S, THR18T, THR39T, THR50T, THR64T, THR87T, TRP53T, TYR58T, TYR73T, TYR92S, TYR92T, VAL104S, VAL104T, VAL110S, VAL112S, VAL116S, VAL150S, VAL15T, VAL35T, VAL51T, VAL52T, VAL54T, VAL82S, VAL8S, VAL93S, VAL93T
• S-U: ALA125S, ALA125U, ALA129S, ALA133S, ALA138S, ALA34S, ALA37S, ARG128S, ARG21U, ARG40S, ARG84U, ASN135S, ASN23U, ASN27S, ASN27U, ASP28S, ASP28U, ASP32S, ASP36S, GLN124S, GLN24S, GLN24U, GLU120U, GLU123S, GLU123U, GLU127S, GLY130S, GLY134S, GLY33S, GLY85U, GLY86U, ILE122S, ILE122U, ILE126S, ILE126U, ILE26S, ILE26U, ILE41S, ILE83U, LEU30S, LEU31S, LYS132S, PHE22U, PHE25S, PHE25U, PHE90U, PRO55U, SER121U, SER29S, THR131S, THR131U, THR39S, THR81U, THR87U, TRP53U, VAL54U, VAL82U
• S-Y: ALA10S, ALA10Y, ALA133S, ALA133Y, ALA37S, ALA37Y, ALA6S, ALA6Y, ALA9S, ALA9Y, ARG128S, ARG128Y, ARG40S, ARG40Y, ASN149S, ASN149Y, ASN7S, ASN7Y, ASP32S, ASP32Y, ASP36S, ASP36Y, GLN43S, GLN43Y, GLU146S, GLU146Y, GLY33S, GLY33Y, GLY42S, GLY42Y, ILE41S, ILE41Y, ILE4S, ILE4Y, LEU142S, LEU142Y, LEU38S, LEU38Y, LYS132S, LYS132Y, LYS5S, LYS5Y, PRO11S, PRO11Y, THR143S, THR143Y, THR39S, THR39Y, VAL150S, VAL150Y, VAL44Y, VAL8S, VAL8Y
• T-Y: ALA125T, ALA125Y, ALA129Y, ALA133Y, ALA138Y, ALA34Y, ALA37Y, ARG128Y, ARG21T, ARG40Y, ARG84T, ASN135Y, ASN23T, ASN27T, ASN27Y, ASP28T, ASP28Y, ASP32Y, ASP36Y, GLN124Y, GLN24T, GLN24Y, GLU120T, GLU123T, GLU123Y, GLU127Y, GLY130Y, GLY134Y, GLY33Y, GLY85T, GLY86T, ILE122T, ILE122Y, ILE126T, ILE126Y, ILE26T, ILE26Y, ILE41Y, ILE83T, LEU30Y, LEU31Y, LYS132Y, PHE22T, PHE25T, PHE25Y, PHE90T, PRO55T, SER121T, SER29Y, THR119T, THR131T, THR131Y, THR39Y, THR81T, THR87T, TRP53T, VAL54T, VAL82T
• T-3: ALA103, ALA10T, ALA1333, ALA133T, ALA373, ALA37T, ALA63, ALA6T, ALA93, ALA9T, ARG1283, ARG128T, ARG403, ARG40T, ASN1493, ASN149T, ASN73, ASN7T, ASP323, ASP32T, ASP363, ASP36T, GLN433, GLN43T, GLU1463, GLU146T, GLY333, GLY33T, GLY423, GLY42T, ILE413, ILE41T, ILE43, ILE4T, LEU1423, LEU142T, LEU383, LEU38T, LYS1323, LYS132T, LYS53, LYS5T, PRO113, PRO11T, THR1433, THR143T, THR393, THR39T, VAL1503, VAL150T, VAL353, VAL35T, VAL443, VAL44T, VAL83, VAL8T
• T-4: ALA1254, ALA125T, ALA129T, ALA133T, ALA138T, ALA34T, ALA37T, ARG128T, ARG214, ARG40T, ARG844, ASN135T, ASN234, ASN274, ASN27T, ASP284, ASP28T, ASP32T, ASP36T, GLN124T, GLN244, GLN24T, GLU1204, GLU1234, GLU123T, GLU127T, GLY130T, GLY134T, GLY33T, GLY854, GLY864, ILE1224, ILE122T, ILE1264, ILE126T, ILE264, ILE26T, ILE41T, ILE834, LEU30T, LEU31T, LYS132T, PHE224, PHE254, PHE25T, PHE904, PRO554, SER1214, SER29T, THR1314, THR131T, THR39T, THR814, THR874, TRP534, VAL544, VAL824
• U-V: ALA102U, ALA102V, ALA105U, ALA113U, ALA125U, ALA133U, ALA140U, ALA144U, ALA153U, ALA16V, ALA57V, ALA63V, ALA66V, ALA68V, ALA6U, ALA75U, ALA78U, ALA88V, ALA94U, ALA97U, ALA97V, ARG128U, ARG14V, ARG21V, ARG84U, ASN2U, ASN48V, ASN7U, ASN99U, ASN99V, ASP107U, ASP107V, ASP28V, ASP32V, ASP36V, ASP46V, ASP47V, ASP74U, GLN106U, GLN106V, GLN124U, GLN24V, GLU120U, GLU127U, GLU139U, GLU146U, GLU59V, GLU65V, GLU91U, GLU91V, GLY100U, GLY100V, GLY109U, GLY115U, GLY56V, GLY85V, GLY86V, GLY95U, GLY95V, GLY96U, GLY96V, HIS89U, HIS89V, ILE148U, ILE154U, ILE17V, ILE19V, ILE3U, ILE49V, ILE4U, ILE83U, LEU101U, LEU101V, LEU117U, LEU142U, LEU145U, LEU151U, LEU31V, LEU38V, LEU60V, LEU62V, LEU67V, LYS136U, LYS45V, LYS5U, LYS69V, LYS72V, MET147U, MET1U, PHE114U, PHE22V, PHE90U, PHE90V, PRO111U, PRO55V, PRO61V, SER103U, SER103V, SER108U, SER121U, SER70V, SER98U, THR118U, THR119U, THR143U, THR18V, THR39V, THR50V, THR64V, THR87V, TRP53V, TYR58V, TYR73V, TYR92U, TYR92V, VAL104U, VAL104V, VAL110U, VAL112U, VAL116U, VAL150U, VAL15V, VAL35V, VAL51V, VAL52V, VAL54V, VAL82U, VAL8U, VAL93U, VAL93V
• U-Y: ALA102Y, ALA105Y, ALA113Y, ALA125Y, ALA140Y, ALA144Y, ALA153Y, ALA16U, ALA20U, ALA57U, ALA63U, ALA66U, ALA68U, ALA6Y, ALA75Y, ALA78Y, ALA88U, ALA94Y, ALA97U, ALA97Y, ARG128Y, ARG14U, ARG21U, ARG84Y, ASN149Y, ASN2Y, ASN48U, ASN7Y, ASN99U, ASN99Y, ASP107U, ASP107Y, ASP28U, ASP32U, ASP36U, ASP46U, ASP47U, ASP74Y, GLN106U, GLN106Y, GLN124Y, GLN24U, GLU120Y, GLU127Y, GLU139Y, GLU146Y, GLU59U, GLU65U, GLU91U, GLU91Y, GLY100U, GLY100Y, GLY109Y, GLY115Y, GLY56U, GLY85U, GLY86U, GLY95U, GLY95Y, GLY96U, GLY96Y, HIS89U, ILE148Y, ILE154Y, ILE17U, ILE19U, ILE3Y, ILE49U, ILE4Y, ILE83Y, LEU101U, LEU101Y, LEU117Y, LEU142Y, LEU145Y, LEU151Y, LEU31U, LEU38U, LEU60U, LEU62U, LEU67U, LYS136Y, LYS45U, LYS5Y, LYS69U, LYS72U, MET147Y, MET1Y, PHE114Y, PHE22U, PHE90U, PHE90Y, PRO111Y, PRO55U, PRO61U, SER103U, SER103Y, SER108Y, SER121Y, SER70U, SER98Y, THR118Y, THR119Y, THR143Y, THR18U, THR39U, THR50U, THR64U, THR87U, TRP53U, TYR58U, TYR73U, TYR92U, TYR92Y, VAL104U, VAL104Y, VAL110Y, VAL112Y, VAL116Y, VAL150Y, VAL15U, VAL35U, VAL51U, VAL52U, VAL54U, VAL82Y, VAL8Y, VAL93U, VAL93Y
• V-W: ALA102V, ALA105V, ALA113V, ALA125V, ALA140V, ALA144V, ALA153V, ALA16W, ALA20W, ALA57W, ALA63W, ALA66W, ALA68W, ALA6V, ALA75V, ALA78V, ALA88W, ALA94V, ALA97V, ALA97W, ARG128V, ARG14W, ARG21W, ARG84V, ASN2V, ASN48W, ASN7V, ASN99V, ASN99W, ASP107V, ASP107W, ASP28W, ASP32W, ASP36W, ASP46W, ASP47W, ASP74V, GLN106V, GLN106W, GLN124V, GLN24W, GLU120V, GLU127V, GLU139V, GLU146V, GLU59W, GLU65W, GLU91V, GLU91W, GLY100V, GLY100W, GLY109V, GLY115V, GLY56W, GLY85W, GLY86W, GLY95V, GLY95W, GLY96V, GLY96W, HIS89V, HIS89W, ILE148V, ILE154V, ILE17W, ILE19W, ILE3V, ILE49W, ILE4V, ILE83V, LEU101V, LEU101W, LEU117V, LEU142V, LEU145V, LEU151V, LEU31W, LEU38W, LEU60W, LEU62W, LEU67W, LYS136V, LYS45W, LYS5V, LYS69W, LYS72W, MET147V, MET1V, PHE114V, PHE22W, PHE90V, PHE90W, PRO111V, PRO55W, PRO61W, SER103V, SER103W, SER108V, SER121V, SER70W, SER98V, THR118V, THR119V, THR143V, THR18W, THR39W, THR50W, THR64W, THR87W, TRP53W, TYR58W, TYR73W, TYR92V, TYR92W, VAL104V, VAL104W, VAL110V, VAL112V, VAL116V, VAL150V, VAL15W, VAL35W, VAL51W, VAL52W, VAL54W, VAL82V, VAL8V, VAL93V, VAL93W
• V-u: ALA6V, ALA6u, ARG40V, ARG40u, ASN7V, ASN7u, ASP36V, ASP36u, GLU146V, GLU146u, LYS5V, LYS5u
• V-v: ARG21v, ARG40V, ASP28V, ASP28v, ASP32V, ASP36V, GLU123V, GLU123v
• W-X: ALA102W, ALA105W, ALA113W, ALA125W, ALA140W, ALA144W, ALA153W, ALA16X, ALA20X, ALA57X, ALA63X, ALA66X, ALA68X, ALA6W, ALA75W, ALA78W, ALA88X, ALA94W, ALA97W, ALA97X, ARG128W, ARG14X, ARG21X, ARG84W, ASN149W, ASN2W, ASN48X, ASN7W, ASN99W, ASN99X, ASP107W, ASP107X, ASP28X, ASP32X, ASP36X, ASP46X, ASP47X, ASP74W, GLN106W, GLN106X, GLN124W, GLN24X, GLU120W, GLU127W, GLU139W, GLU146W, GLU59X, GLU65X, GLU91W, GLU91X, GLY100W, GLY100X, GLY109W, GLY115W, GLY56X, GLY85X, GLY86X, GLY95W, GLY95X, GLY96W, GLY96X, HIS89W, HIS89X, ILE148W, ILE154W, ILE17X, ILE19X, ILE3W, ILE49X, ILE4W, ILE83W, LEU101W, LEU101X, LEU117W, LEU142W, LEU145W, LEU151W, LEU31X, LEU38X, LEU60X, LEU62X, LEU67X, LYS136W, LYS45X, LYS5W, LYS69X, LYS72X, MET147W, MET1W, PHE114W, PHE22X, PHE90W, PHE90X, PRO111W, PRO55X, PRO61X, SER103W, SER103X, SER108W, SER121W, SER70X, SER98W, THR118W, THR119W, THR143W, THR18X, THR39X, THR50X, THR64X, THR87X, TRP53X, TYR58X, TYR73X, TYR92W, TYR92X, VAL104W, VAL104X, VAL110W, VAL112W, VAL116W, VAL150W, VAL15X, VAL35X, VAL51X, VAL52X, VAL54X, VAL82W, VAL8W, VAL93W, VAL93X
• W-r: 5-9.7018642.907696LYS, 6-5.5921482.836609ALA, 7-5.0798412.570414ASN, ALA6W, ARG40-4.3403982.698485, ARG40-4.5536612.591593, ARG40-6.7965222.755847, ARG40W, ARG40r, ASN7W, ASP36-8.0875163.039244, ASP36W, ASP36r, GLU146-4.3573612.661769, GLU146W, GLU146r, LYS5W, LYS5r
• W-s: ARG21s, ARG40W, ASP28W, ASP28s, ASP32W, ASP36W, GLU123W, GLU123s
• W-u: ARG21W, ARG40u, ASP28W, ASP28u, ASP32u, ASP36u, GLU123W, GLU123u, GLY130u, PHE25W
• X-Y: ALA102X, ALA102Y, ALA105X, ALA113X, ALA125X, ALA133X, ALA140X, ALA144X, ALA153X, ALA16Y, ALA57Y, ALA63Y, ALA66Y, ALA68Y, ALA6X, ALA75X, ALA78X, ALA88Y, ALA94X, ALA97X, ALA97Y, ARG128X, ARG14Y, ARG21Y, ARG84X, ASN2X, ASN48Y, ASN7X, ASN99X, ASN99Y, ASP107X, ASP107Y, ASP28Y, ASP32Y, ASP36Y, ASP46Y, ASP47Y, ASP74X, GLN106X, GLN106Y, GLN124X, GLN24Y, GLU120X, GLU127X, GLU139X, GLU146X, GLU59Y, GLU65Y, GLU91X, GLU91Y, GLY100X, GLY100Y, GLY109X, GLY115X, GLY56Y, GLY85Y, GLY86Y, GLY95X, GLY95Y, GLY96X, GLY96Y, HIS89Y, ILE148X, ILE154X, ILE17Y, ILE19Y, ILE3X, ILE49Y, ILE4X, ILE83X, LEU101X, LEU101Y, LEU117X, LEU142X, LEU145X, LEU151X, LEU31Y, LEU38Y, LEU60Y, LEU62Y, LEU67Y, LYS136X, LYS45Y, LYS5X, LYS69Y, LYS72Y, MET147X, MET1X, PHE114X, PHE22Y, PHE90X, PHE90Y, PRO111X, PRO55Y, PRO61Y, SER103X, SER103Y, SER108X, SER121X, SER70Y, SER98X, THR118X, THR119X, THR143X, THR18Y, THR39Y, THR50Y, THR64Y, THR87Y, TRP53Y, TYR58Y, TYR73Y, TYR92X, TYR92Y, VAL104X, VAL104Y, VAL110X, VAL112X, VAL116X, VAL150X, VAL15Y, VAL35Y, VAL51Y, VAL52Y, VAL54Y, VAL82X, VAL8X, VAL93X, VAL93Y
• X-Z: ALA125X, ALA125Z, ALA129X, ALA133X, ALA138X, ALA34X, ALA37X, ARG128X, ARG21Z, ARG40X, ARG84Z, ASN135X, ASN23Z, ASN27X, ASN27Z, ASP28X, ASP28Z, ASP32X, ASP36X, GLN124X, GLN24X, GLN24Z, GLU120Z, GLU123X, GLU123Z, GLU127X, GLY130X, GLY134X, GLY33X, GLY85Z, GLY86Z, ILE122X, ILE122Z, ILE126X, ILE126Z, ILE26X, ILE26Z, ILE41X, ILE83Z, LEU30X, LEU31X, LYS132X, PHE22Z, PHE25X, PHE25Z, PHE90Z, PRO55Z, SER121Z, SER29X, THR119Z, THR131X, THR131Z, THR39X, THR81Z, THR87Z, TRP53Z, VAL54Z, VAL82Z
• X-4: ALA104, ALA10X, ALA1334, ALA133X, ALA374, ALA37X, ALA64, ALA6X, ALA94, ALA9X, ARG1284, ARG128X, ARG404, ARG40X, ASN1494, ASN149X, ASN74, ASN7X, ASP324, ASP32X, ASP364, ASP36X, GLN434, GLN43X, GLU1464, GLU146X, GLY334, GLY33X, GLY424, GLY42X, ILE414, ILE41X, ILE44, ILE4X, LEU1424, LEU142X, LEU384, LEU38X, LYS1324, LYS132X, LYS54, LYS5X, PRO114, PRO11X, THR1434, THR143X, THR394, THR39X, VAL1504, VAL150X, VAL354, VAL444, VAL44X, VAL84, VAL8X
• X-r: ARG21X, ARG40r, ARG84X, ASP28X, ASP28r, ASP32r, ASP36-6.9170062.826512, ASP36r, GLU123X, GLU123r, GLY130-6.2613673.199241, LYS132-3.5423183.257203, PHE25X
• Y-4: ALA1254, ALA125Y, ALA1294, ALA1334, ALA1384, ALA344, ALA374, ARG1284, ARG21Y, ARG404, ARG84Y, ASN1354, ASN23Y, ASN274, ASN27Y, ASP284, ASP28Y, ASP324, ASP364, GLN1244, GLN244, GLN24Y, GLU120Y, GLU1234, GLU123Y, GLU1274, GLY1304, GLY1344, GLY334, GLY85Y, GLY86Y, ILE1224, ILE122Y, ILE1264, ILE126Y, ILE264, ILE26Y, ILE414, ILE83Y, LEU304, LEU314, LYS1324, PHE22Y, PHE254, PHE25Y, PHE90Y, PRO55Y, SER121Y, SER294, THR1314, THR131Y, THR394, THR81Y, THR87Y, TRP53Y, VAL54Y, VAL82Y
• Z-1: ALA102Z, ALA105Z, ALA113Z, ALA125Z, ALA140Z, ALA144Z, ALA153Z, ALA161, ALA571, ALA631, ALA661, ALA681, ALA6Z, ALA75Z, ALA78Z, ALA881, ALA94Z, ALA971, ALA97Z, ARG128Z, ARG141, ARG211, ARG84Z, ASN2Z, ASN481, ASN7Z, ASN991, ASN99Z, ASP1071, ASP107Z, ASP281, ASP321, ASP361, ASP461, ASP471, ASP74Z, GLN1061, GLN106Z, GLN124Z, GLN241, GLU120Z, GLU127Z, GLU139Z, GLU146Z, GLU591, GLU651, GLU911, GLU91Z, GLY1001, GLY100Z, GLY109Z, GLY115Z, GLY561, GLY851, GLY861, GLY951, GLY95Z, GLY961, GLY96Z, HIS891, ILE148Z, ILE154Z, ILE171, ILE191, ILE3Z, ILE491, ILE4Z, ILE83Z, LEU1011, LEU101Z, LEU117Z, LEU142Z, LEU145Z, LEU151Z, LEU311, LEU381, LEU601, LEU621, LEU671, LYS136Z, LYS451, LYS5Z, LYS691, LYS721, MET147Z, MET1Z, PHE114Z, PHE221, PHE901, PHE90Z, PRO111Z, PRO551, PRO611, SER1031, SER103Z, SER108Z, SER121Z, SER701, SER98Z, THR118Z, THR119Z, THR143Z, THR181, THR391, THR501, THR641, THR871, TRP531, TYR581, TYR731, TYR921, TYR92Z, VAL1041, VAL104Z, VAL110Z, VAL112Z, VAL116Z, VAL150Z, VAL151, VAL351, VAL511, VAL521, VAL541, VAL82Z, VAL8Z, VAL931, VAL93Z
• Z-4: ALA1024, ALA102Z, ALA1054, ALA1134, ALA1254, ALA1334, ALA1404, ALA1444, ALA1534, ALA16Z, ALA57Z, ALA63Z, ALA64, ALA66Z, ALA68Z, ALA754, ALA784, ALA88Z, ALA944, ALA974, ALA97Z, ARG1284, ARG14Z, ARG21Z, ARG844, ASN24, ASN48Z, ASN74, ASN994, ASN99Z, ASP1074, ASP107Z, ASP28Z, ASP32Z, ASP36Z, ASP46Z, ASP47Z, ASP744, GLN1064, GLN106Z, GLN1244, GLN24Z, GLU1204, GLU1274, GLU1394, GLU1464, GLU59Z, GLU65Z, GLU914, GLU91Z, GLY1004, GLY100Z, GLY1094, GLY1154, GLY56Z, GLY85Z, GLY86Z, GLY954, GLY95Z, GLY964, GLY96Z, HIS89Z, ILE1484, ILE1544, ILE17Z, ILE19Z, ILE34, ILE44, ILE49Z, ILE834, LEU1014, LEU101Z, LEU1174, LEU1424, LEU1454, LEU1514, LEU31Z, LEU38Z, LEU60Z, LEU62Z, LEU67Z, LYS1364, LYS45Z, LYS54, LYS69Z, LYS72Z, MET14, MET1474, PHE1144, PHE22Z, PHE904, PHE90Z, PRO1114, PRO55Z, PRO61Z, SER1034, SER103Z, SER1084, SER1214, SER70Z, SER984, THR1184, THR1194, THR1434, THR18Z, THR39Z, THR50Z, THR64Z, THR87Z, TRP53Z, TYR58Z, TYR73Z, TYR924, TYR92Z, VAL1044, VAL104Z, VAL1104, VAL1124, VAL1164, VAL1504, VAL15Z, VAL35Z, VAL51Z, VAL52Z, VAL54Z, VAL824, VAL84, VAL934, VAL93Z
• Z-q: ALA6Z, ALA6q, ARG40Z, ARG40q, ASN7Z, ASN7q, ASP36Z, ASP36q, GLU146Z, GLU146q, LYS5Z, LYS5q
• Z-r: ARG21-5.3928793.076475, ARG21r, ARG40Z, ASP28Z, ASP28r, ASP32Z, ASP36Z, GLU123Z, GLU123r, GLY130Z, PHE25-8.4003183.134342
• 1-2: ALA1021, ALA1051, ALA1131, ALA1251, ALA1331, ALA1401, ALA1441, ALA1531, ALA162, ALA572, ALA61, ALA632, ALA662, ALA682, ALA751, ALA781, ALA882, ALA941, ALA971, ALA972, ARG1281, ARG142, ARG212, ARG841, ASN21, ASN482, ASN71, ASN991, ASN992, ASP1071, ASP1072, ASP282, ASP322, ASP362, ASP462, ASP472, GLN1061, GLN1062, GLN1241, GLN242, GLU1201, GLU1271, GLU1391, GLU1461, GLU592, GLU652, GLU911, GLU912, GLY1001, GLY1002, GLY1091, GLY1151, GLY562, GLY852, GLY862, GLY951, GLY952, GLY961, GLY962, HIS891, HIS892, ILE1481, ILE1541, ILE172, ILE192, ILE31, ILE41, ILE492, ILE831, LEU1011, LEU1012, LEU1171, LEU1421, LEU1451, LEU1511, LEU312, LEU382, LEU602, LEU622, LEU672, LYS1361, LYS452, LYS51, LYS692, LYS722, MET11, MET1471, PHE1141, PHE222, PHE901, PHE902, PRO1111, PRO552, PRO612, SER1031, SER1032, SER1081, SER1211, SER702, SER981, THR1181, THR1191, THR1431, THR182, THR392, THR502, THR642, THR872, TRP532, TYR582, TYR732, TYR921, TYR922, VAL1041, VAL1042, VAL1101, VAL1121, VAL1161, VAL1501, VAL152, VAL352, VAL512, VAL522, VAL542, VAL81, VAL821, VAL931, VAL932
• 1-5: ALA101, ALA105, ALA1331, ALA1335, ALA371, ALA375, ALA61, ALA65, ALA91, ALA95, ARG1281, ARG1285, ARG401, ARG405, ASN1491, ASN1495, ASN71, ASN75, ASP321, ASP325, ASP361, ASP365, GLN431, GLN435, GLU1461, GLU1465, GLY331, GLY335, GLY421, GLY425, ILE41, ILE411, ILE415, ILE45, LEU1421, LEU1425, LEU381, LEU385, LYS1321, LYS1325, LYS51, LYS55, PRO111, PRO115, THR1431, THR1435, THR391, THR395, VAL1501, VAL1505, VAL445, VAL81, VAL85
• 1-6: ALA1251, ALA1256, ALA1291, ALA1331, ALA1381, ALA341, ALA371, ARG1281, ARG216, ARG401, ARG846, ASN1351, ASN236, ASN271, ASN276, ASP281, ASP286, ASP321, ASP361, GLN1241, GLN241, GLN246, GLU1206, GLU1231, GLU1236, GLU1271, GLY1301, GLY1341, GLY331, GLY856, GLY866, ILE1221, ILE1226, ILE1261, ILE1266, ILE261, ILE266, ILE411, ILE836, LEU301, LEU311, LYS1321, PHE226, PHE251, PHE256, PHE906, PRO556, SER1216, SER291, THR1196, THR1311, THR1316, THR391, THR816, THR876, TRP536, VAL546, VAL826
• 1-q: ARG211, ARG40q, ASP281, ASP28q, ASP32q, ASP36q, GLU1231, GLU123q
• 2-3: ALA1022, ALA1023, ALA1052, ALA1132, ALA1252, ALA1402, ALA1442, ALA1532, ALA163, ALA573, ALA62, ALA633, ALA663, ALA683, ALA752, ALA782, ALA883, ALA942, ALA972, ALA973, ARG1282, ARG143, ARG213, ARG842, ASN22, ASN483, ASN72, ASN992, ASN993, ASP1072, ASP1073, ASP283, ASP323, ASP363, ASP463, ASP473, ASP742, GLN1062, GLN1063, GLN1242, GLN243, GLU1202, GLU1272, GLU1392, GLU1462, GLU593, GLU653, GLU912, GLU913, GLY1002, GLY1003, GLY1092, GLY1152, GLY563, GLY853, GLY863, GLY952, GLY953, GLY962, GLY963, HIS892, HIS893, ILE1482, ILE1542, ILE173, ILE193, ILE32, ILE42, ILE493, ILE832, LEU1012, LEU1013, LEU1172, LEU1422, LEU1452, LEU1512, LEU313, LEU383, LEU603, LEU623, LEU673, LYS1362, LYS453, LYS52, LYS693, LYS723, MET12, MET1472, PHE1142, PHE223, PHE902, PHE903, PRO1112, PRO553, PRO613, SER1032, SER1033, SER1082, SER1212, SER703, SER982, THR1182, THR1192, THR1432, THR183, THR393, THR503, THR643, THR873, TRP533, TYR583, TYR733, TYR922, TYR923, VAL1042, VAL1043, VAL1102, VAL1122, VAL1162, VAL1502, VAL153, VAL353, VAL513, VAL523, VAL543, VAL82, VAL822, VAL932, VAL933
• 2-5: ALA1252, ALA1255, ALA1295, ALA1335, ALA1385, ALA345, ALA375, ARG1285, ARG212, ARG405, ARG842, ASN1355, ASN232, ASN272, ASN275, ASP282, ASP285, ASP325, ASP365, GLN1245, GLN242, GLN245, GLU1202, GLU1232, GLU1235, GLU1275, GLY1305, GLY1345, GLY335, GLY852, GLY862, ILE1222, ILE1225, ILE1262, ILE1265, ILE262, ILE265, ILE415, ILE832, LEU305, LEU315, LYS1325, PHE222, PHE252, PHE255, PHE902, PRO552, SER1212, SER295, THR1312, THR1315, THR395, THR812, THR872, TRP532, VAL542, VAL822
• 2-h: ALA102, ALA10h, ALA1332, ALA133h, ALA372, ALA37h, ALA62, ALA6h, ALA92, ALA9h, ARG1282, ARG128h, ARG402, ARG40h, ASN1492, ASN149h, ASN72, ASN7h, ASP322, ASP32h, ASP362, ASP36h, GLN432, GLN43h, GLU1462, GLU146h, GLY332, GLY33h, GLY422, GLY42h, ILE412, ILE41h, ILE42, ILE4h, LEU1422, LEU142h, LEU382, LEU38h, LYS1322, LYS132h, LYS52, LYS5h, PRO112, PRO11h, THR1432, THR143h, THR392, THR39h, VAL1502, VAL150h, VAL352, VAL35h, VAL442, VAL44h, VAL82, VAL8h
• 2-i: ALA1252, ALA125i, ALA1292, ALA1332, ALA1382, ALA342, ALA372, ARG1282, ARG21i, ARG402, ARG84i, ASN1352, ASN23i, ASN272, ASN27i, ASP282, ASP28i, ASP322, ASP362, GLN1242, GLN242, GLN24i, GLU120i, GLU1232, GLU123i, GLU1272, GLY1302, GLY1342, GLY332, GLY85i, GLY86i, ILE1222, ILE122i, ILE1262, ILE126i, ILE262, ILE26i, ILE412, ILE83i, LEU302, LEU312, LYS1322, PHE22i, PHE252, PHE25i, PHE90i, PRO55i, SER121i, SER292, THR119i, THR1312, THR131i, THR392, THR81i, THR87i, TRP53i, VAL54i, VAL82i
• 3-4: ALA1023, ALA1024, ALA1053, ALA1133, ALA1253, ALA1333, ALA1403, ALA1443, ALA1533, ALA164, ALA574, ALA63, ALA634, ALA664, ALA684, ALA753, ALA783, ALA884, ALA943, ALA973, ALA974, ARG1283, ARG144, ARG214, ARG843, ASN23, ASN484, ASN73, ASN993, ASN994, ASP1073, ASP1074, ASP284, ASP324, ASP364, ASP464, ASP474, ASP743, GLN1063, GLN1064, GLN1243, GLN244, GLU1203, GLU1273, GLU1393, GLU1463, GLU594, GLU654, GLU913, GLU914, GLY1003, GLY1004, GLY1093, GLY1153, GLY564, GLY854, GLY864, GLY953, GLY954, GLY963, GLY964, HIS893, HIS894, ILE1483, ILE1543, ILE174, ILE194, ILE33, ILE43, ILE494, ILE833, LEU1013, LEU1014, LEU1173, LEU1423, LEU1453, LEU1513, LEU314, LEU384, LEU604, LEU624, LEU674, LYS1363, LYS454, LYS53, LYS694, LYS724, MET13, MET1473, PHE1143, PHE224, PHE903, PHE904, PRO1113, PRO554, PRO614, SER1033, SER1034, SER1083, SER1213, SER704, SER983, THR1183, THR1193, THR1433, THR184, THR394, THR504, THR644, THR874, TRP534, TYR584, TYR734, TYR923, TYR924, VAL1043, VAL1044, VAL1103, VAL1123, VAL1163, VAL1503, VAL154, VAL354, VAL514, VAL524, VAL544, VAL823, VAL83, VAL933, VAL934
• 3-h: ALA1253, ALA125h, ALA129h, ALA133h, ALA138h, ALA34h, ALA37h, ARG128h, ARG213, ARG40h, ARG843, ASN135h, ASN233, ASN273, ASN27h, ASP283, ASP28h, ASP32h, ASP36h, GLN124h, GLN243, GLN24h, GLU1203, GLU1233, GLU123h, GLU127h, GLY130h, GLY134h, GLY33h, GLY853, GLY863, ILE1223, ILE122h, ILE1263, ILE126h, ILE263, ILE26h, ILE41h, ILE833, LEU30h, LEU31h, LYS132h, PHE223, PHE253, PHE25h, PHE903, PRO553, SER1213, SER29h, THR1313, THR131h, THR39h, THR813, THR873, TRP533, VAL543, VAL823
• 5-6: ALA1025, ALA1055, ALA1135, ALA1255, ALA1405, ALA1445, ALA1535, ALA166, ALA576, ALA636, ALA65, ALA666, ALA686, ALA755, ALA785, ALA886, ALA945, ALA975, ALA976, ARG1285, ARG146, ARG216, ARG845, ASN25, ASN486, ASN75, ASN995, ASN996, ASP1075, ASP1076, ASP286, ASP326, ASP366, ASP466, ASP476, GLN1065, GLN1066, GLN1245, GLN246, GLU1205, GLU1275, GLU1395, GLU1465, GLU596, GLU656, GLU915, GLU916, GLY1005, GLY1006, GLY1095, GLY1155, GLY566, GLY856, GLY866, GLY955, GLY956, GLY965, GLY966, HIS896, ILE1485, ILE1545, ILE176, ILE196, ILE35, ILE45, ILE496, ILE835, LEU1015, LEU1016, LEU1175, LEU1425, LEU1455, LEU1515, LEU316, LEU386, LEU606, LEU626, LEU676, LYS1365, LYS456, LYS55, LYS696, LYS726, MET1475, MET15, PHE1145, PHE226, PHE905, PHE906, PRO1115, PRO556, PRO616, SER1035, SER1036, SER1085, SER1215, SER706, SER985, THR1185, THR1195, THR1435, THR186, THR396, THR506, THR646, THR876, TRP536, TYR586, TYR736, TYR925, TYR926, VAL1045, VAL1046, VAL1105, VAL1125, VAL1165, VAL1505, VAL156, VAL356, VAL516, VAL526, VAL546, VAL825, VAL85, VAL935, VAL936
• 5-9: ALA1025, ALA1029, ALA1059, ALA1139, ALA1259, ALA1409, ALA1449, ALA1539, ALA165, ALA575, ALA635, ALA665, ALA685, ALA69, ALA759, ALA789, ALA885, ALA945, ALA949, ALA975, ALA979, ARG1289, ARG145, ARG215, ARG849, ASN1499, ASN29, ASN485, ASN79, ASN995, ASN999, ASP1075, ASP1079, ASP285, ASP325, ASP365, ASP465, ASP475, ASP749, GLN1065, GLN1069, GLN1249, GLN245, GLU1209, GLU1279, GLU1399, GLU1469, GLU595, GLU655, GLU915, GLU919, GLY1005, GLY1009, GLY1099, GLY1159, GLY565, GLY855, GLY865, GLY955, GLY959, GLY965, GLY969, HIS895, HIS899, ILE1489, ILE1549, ILE175, ILE195, ILE39, ILE49, ILE495, ILE839, LEU1015, LEU1019, LEU1179, LEU1429, LEU1459, LEU1519, LEU315, LEU385, LEU605, LEU625, LEU675, LYS1369, LYS455, LYS59, LYS695, LYS725, MET1479, MET19, PHE1149, PHE225, PHE905, PHE909, PRO1119, PRO555, PRO615, SER1035, SER1039, SER1089, SER1219, SER705, SER989, THR1189, THR1199, THR1439, THR185, THR395, THR505, THR645, THR875, TRP535, TYR585, TYR735, TYR925, TYR929, VAL1045, VAL1049, VAL1109, VAL1129, VAL1169, VAL1509, VAL155, VAL355, VAL515, VAL525, VAL545, VAL829, VAL89, VAL935, VAL939
• 5-i: ALA1255, ALA125i, ALA129i, ALA133i, ALA138i, ALA34i, ALA37i, ARG128i, ARG215, ARG40i, ARG845, ASN135i, ASN235, ASN275, ASN27i, ASP285, ASP28i, ASP32i, ASP36i, GLN124i, GLN245, GLN24i, GLU1205, GLU1235, GLU123i, GLU127i, GLY130i, GLY134i, GLY33i, GLY855, GLY865, ILE1225, ILE122i, ILE1265, ILE126i, ILE265, ILE26i, ILE41i, ILE835, LEU30i, LEU31i, LYS132i, PHE225, PHE255, PHE25i, PHE905, PRO555, SER1215, SER29i, THR1195, THR1315, THR131i, THR39i, THR815, THR875, TRP535, VAL545, VAL825
• 6-7: ALA1026, ALA1056, ALA1136, ALA1256, ALA1406, ALA1446, ALA1536, ALA167, ALA577, ALA637, ALA66, ALA667, ALA687, ALA756, ALA786, ALA887, ALA946, ALA976, ALA977, ARG1286, ARG147, ARG217, ARG846, ASN26, ASN487, ASN76, ASN996, ASN997, ASP1076, ASP1077, ASP287, ASP327, ASP367, ASP467, ASP477, GLN1066, GLN1067, GLN1246, GLN247, GLU1206, GLU1276, GLU1396, GLU1466, GLU597, GLU657, GLU916, GLU917, GLY1006, GLY1007, GLY1096, GLY1156, GLY567, GLY857, GLY867, GLY956, GLY957, GLY966, GLY967, HIS897, ILE1486, ILE1546, ILE177, ILE197, ILE36, ILE46, ILE497, ILE836, LEU1016, LEU1017, LEU1176, LEU1426, LEU1456, LEU1516, LEU317, LEU387, LEU607, LEU627, LEU677, LYS1366, LYS457, LYS56, LYS697, LYS727, MET1476, MET16, PHE1146, PHE227, PHE906, PHE907, PRO1116, PRO557, PRO617, SER1036, SER1037, SER1086, SER1216, SER707, SER986, THR1186, THR1196, THR1436, THR187, THR397, THR507, THR647, THR877, TRP537, TYR587, TYR737, TYR926, TYR927, VAL1046, VAL1047, VAL1106, VAL1126, VAL1166, VAL1506, VAL157, VAL357, VAL517, VAL527, VAL547, VAL826, VAL86, VAL936, VAL937
• 6-p: ALA66, ALA6p, ARG406, ARG40p, ASN76, ASN7p, ASP366, ASP36p, GLU1466, GLU146p, LYS56, LYS5p
• 6-q: ARG21q, ARG406, ASP286, ASP28q, ASP326, ASP366, GLU1236, GLU123q, GLY1306, PHE25q
• 7-8: ALA1027, ALA1057, ALA1137, ALA1257, ALA1407, ALA1447, ALA1537, ALA168, ALA578, ALA638, ALA668, ALA67, ALA688, ALA757, ALA787, ALA888, ALA947, ALA977, ALA978, ARG1287, ARG148, ARG218, ARG847, ASN27, ASN488, ASN77, ASN997, ASN998, ASP1077, ASP1078, ASP288, ASP328, ASP368, ASP468, ASP478, ASP747, GLN1067, GLN1068, GLN1247, GLN248, GLU1207, GLU1277, GLU1397, GLU1467, GLU598, GLU658, GLU917, GLU918, GLY1007, GLY1008, GLY1097, GLY1157, GLY568, GLY858, GLY868, GLY957, GLY958, GLY967, GLY968, HIS898, ILE1487, ILE1547, ILE178, ILE198, ILE37, ILE47, ILE498, ILE837, LEU1017, LEU1018, LEU1177, LEU1427, LEU1457, LEU1517, LEU318, LEU388, LEU608, LEU628, LEU678, LYS1367, LYS458, LYS57, LYS698, LYS728, MET1477, MET17, PHE1147, PHE228, PHE907, PHE908, PRO1117, PRO558, PRO618, SER1037, SER1038, SER1087, SER1217, SER708, SER987, THR1187, THR1197, THR1437, THR188, THR398, THR508, THR648, THR878, TRP538, TYR588, TYR738, TYR927, TYR928, VAL1047, VAL1048, VAL1107, VAL1127, VAL1167, VAL1507, VAL158, VAL358, VAL518, VAL528, VAL548, VAL827, VAL87, VAL937, VAL938
• 7-m: ALA67, ALA6m, ARG407, ARG40m, ASN77, ASN7m, ASP367, ASP36m, GLU1467, GLU146m, LYS57, LYS5m
• 7-n: ARG21n, ARG407, ASP287, ASP28n, ASP327, ASP367, GLU1237, GLU123n, GLY1307, PHE25n
• 7-p: ARG217, ARG40p, ASP287, ASP32p, ASP36p, GLU1237, GLU123p, GLY130p, PHE257
• 8-9: ALA1028, ALA1058, ALA1138, ALA1258, ALA1408, ALA1448, ALA1538, ALA169, ALA579, ALA639, ALA669, ALA68, ALA689, ALA758, ALA788, ALA889, ALA948, ALA949, ALA978, ALA979, ARG1288, ARG149, ARG219, ARG848, ASN28, ASN489, ASN78, ASN998, ASN999, ASP1078, ASP1079, ASP289, ASP329, ASP369, ASP469, ASP479, GLN1068, GLN1069, GLN1248, GLN249, GLU1208, GLU1278, GLU1398, GLU1468, GLU599, GLU659, GLU918, GLU919, GLY1008, GLY1009, GLY1098, GLY1158, GLY569, GLY859, GLY869, GLY958, GLY959, GLY968, GLY969, HIS898, HIS899, ILE1488, ILE1548, ILE179, ILE199, ILE38, ILE48, ILE499, ILE838, LEU1018, LEU1019, LEU1178, LEU1428, LEU1458, LEU1518, LEU319, LEU389, LEU609, LEU629, LEU679, LYS1368, LYS459, LYS58, LYS699, LYS729, MET1478, MET18, PHE1148, PHE229, PHE908, PHE909, PRO1118, PRO559, PRO619, SER1038, SER1039, SER1088, SER1218, SER709, SER988, THR1188, THR1198, THR1438, THR189, THR399, THR509, THR649, THR879, TRP539, TYR589, TYR739, TYR928, TYR929, VAL1048, VAL1049, VAL1108, VAL1128, VAL1168, VAL1508, VAL159, VAL359, VAL519, VAL529, VAL549, VAL828, VAL88, VAL938, VAL939
• 8-a: ALA1258, ALA125a, ALA1298, ALA1338, ALA1388, ALA348, ALA378, ARG1288, ARG21a, ARG408, ARG84a, ASN1358, ASN23a, ASN278, ASN27a, ASP288, ASP28a, ASP328, ASP368, GLN1248, GLN248, GLN24a, GLU120a, GLU1238, GLU123a, GLU1278, GLY1308, GLY1348, GLY338, GLY85a, GLY86a, ILE1228, ILE122a, ILE1268, ILE126a, ILE268, ILE26a, ILE418, ILE83a, LEU308, LEU318, LYS1328, PHE22a, PHE258, PHE25a, PHE90a, PRO55a, SER121a, SER298, THR119a, THR1318, THR131a, THR81a, THR87a, TRP53a, VAL54a, VAL82a
• 8-e: ALA108, ALA10e, ALA1338, ALA133e, ALA378, ALA37e, ALA68, ALA6e, ALA98, ALA9e, ARG1288, ARG128e, ARG408, ARG40e, ASN1498, ASN149e, ASN78, ASN7e, ASP328, ASP32e, ASP368, ASP36e, GLN438, GLN43e, GLU1468, GLU146e, GLY338, GLY33e, GLY428, GLY42e, ILE418, ILE41e, ILE48, ILE4e, LEU1428, LEU142e, LEU388, LEU38e, LYS1328, LYS132e, LYS58, LYS5e, PRO118, PRO11e, THR1438, THR143e, THR398, THR39e, VAL1508, VAL150e, VAL358, VAL448, VAL88, VAL8e
• 8-m: ARG218, ARG40m, ASP288, ASP28m, ASP32m, ASP36m, GLU1238, GLU123m, GLY130m, PHE258
• 9-e: ALA1259, ALA125e, ALA129e, ALA133e, ALA138e, ALA34e, ALA37e, ARG128e, ARG219, ARG40e, ARG849, ASN135e, ASN239, ASN279, ASN27e, ASP289, ASP28e, ASP32e, ASP36e, GLN124e, GLN249, GLN24e, GLU1209, GLU1239, GLU123e, GLU127e, GLY130e, GLY134e, GLY33e, GLY859, GLY869, ILE1229, ILE122e, ILE1269, ILE126e, ILE269, ILE26e, ILE41e, ILE839, LEU30e, LEU31e, LYS132e, PHE229, PHE259, PHE25e, PHE909, PRO559, SER1219, SER29e, THR1199, THR1319, THR131e, THR39e, THR819, THR879, TRP539, VAL549, VAL829
• 9-i: ALA109, ALA10i, ALA1339, ALA133i, ALA379, ALA37i, ALA69, ALA6i, ALA99, ALA9i, ARG1289, ARG128i, ARG409, ARG40i, ASN1499, ASN149i, ASN79, ASN7i, ASP329, ASP32i, ASP369, ASP36i, GLN439, GLN43i, GLU1469, GLU146i, GLY339, GLY33i, GLY429, GLY42i, ILE419, ILE41i, ILE49, ILE4i, LEU1429, LEU142i, LEU389, LEU38i, LYS1329, LYS132i, LYS59, LYS5i, PRO119, PRO11i, THR1439, THR143i, THR399, THR39i, VAL1509, VAL150i, VAL359, VAL35i, VAL449, VAL44i, VAL89, VAL8i
• 9-j: ALA1259, ALA125j, ALA1299, ALA1339, ALA1389, ALA349, ALA379, ARG1289, ARG21j, ARG409, ARG84j, ASN1359, ASN23j, ASN279, ASN27j, ASP289, ASP28j, ASP329, ASP369, GLN1249, GLN249, GLN24j, GLU120j, GLU1239, GLU123j, GLU1279, GLY1309, GLY1349, GLY339, GLY85j, GLY86j, ILE1229, ILE122j, ILE1269, ILE126j, ILE269, ILE26j, ILE419, ILE83j, LEU309, LEU319, LYS1329, PHE22j, PHE259, PHE25j, PHE90j, PRO55j, SER121j, SER299, THR1319, THR131j, THR399, THR81j, THR87j, TRP53j, VAL54j, VAL82j
• a-b: ALA102a, ALA105a, ALA113a, ALA125a, ALA140a, ALA144a, ALA153a, ALA16b, ALA57b, ALA63b, ALA66b, ALA68b, ALA6a, ALA75a, ALA78a, ALA88b, ALA94a, ALA97a, ALA97b, ARG128a, ARG14b, ARG21b, ARG84a, ASN2a, ASN48b, ASN7a, ASN99a, ASN99b, ASP107a, ASP107b, ASP28b, ASP32b, ASP36b, ASP46b, ASP47b, ASP74a, GLN106a, GLN106b, GLN124a, GLN24b, GLU120a, GLU127a, GLU139a, GLU146a, GLU59b, GLU65b, GLU91a, GLU91b, GLY100a, GLY100b, GLY109a, GLY115a, GLY56b, GLY85b, GLY86b, GLY95a, GLY95b, GLY96a, GLY96b, HIS89b, ILE148a, ILE154a, ILE17b, ILE19b, ILE3a, ILE49b, ILE4a, ILE83a, LEU101a, LEU101b, LEU117a, LEU142a, LEU145a, LEU151a, LEU31b, LEU38b, LEU60b, LEU62b, LEU67b, LYS136a, LYS45b, LYS5a, LYS69b, LYS72b, MET147a, MET1a, PHE114a, PHE22b, PHE90a, PHE90b, PRO111a, PRO55b, PRO61b, SER103a, SER103b, SER108a, SER121a, SER70b, SER98a, THR118a, THR119a, THR143a, THR18b, THR39b, THR50b, THR64b, THR87b, TRP53b, TYR58b, TYR73b, TYR92a, TYR92b, VAL104a, VAL104b, VAL110a, VAL112a, VAL116a, VAL150a, VAL15b, VAL35b, VAL51b, VAL52b, VAL54b, VAL82a, VAL8a, VAL93a, VAL93b
• a-e: ALA102a, ALA102e, ALA105e, ALA113e, ALA125e, ALA140e, ALA144e, ALA153e, ALA16a, ALA57a, ALA63a, ALA66a, ALA68a, ALA6e, ALA75e, ALA78e, ALA88a, ALA94e, ALA97a, ALA97e, ARG128e, ARG14a, ARG21a, ARG84e, ASN2e, ASN48a, ASN7e, ASN99a, ASN99e, ASP107a, ASP107e, ASP28a, ASP32a, ASP36a, ASP46a, ASP47a, GLN106a, GLN106e, GLN124e, GLN24a, GLU120e, GLU127e, GLU139e, GLU146e, GLU59a, GLU65a, GLU91a, GLU91e, GLY100a, GLY100e, GLY109e, GLY115e, GLY56a, GLY85a, GLY86a, GLY95a, GLY95e, GLY96a, GLY96e, HIS89a, ILE148e, ILE154e, ILE17a, ILE19a, ILE3e, ILE49a, ILE4e, ILE83e, LEU101a, LEU101e, LEU117e, LEU142e, LEU145e, LEU151e, LEU31a, LEU38a, LEU60a, LEU62a, LEU67a, LYS136e, LYS45a, LYS5e, LYS69a, LYS72a, MET147e, MET1e, PHE114e, PHE22a, PHE90a, PHE90e, PRO111e, PRO55a, PRO61a, SER103a, SER103e, SER108e, SER121e, SER70a, SER98e, THR118e, THR119e, THR143e, THR18a, THR39a, THR50a, THR64a, THR87a, TRP53a, TYR58a, TYR73a, TYR92a, TYR92e, VAL104a, VAL104e, VAL110e, VAL112e, VAL116e, VAL150e, VAL15a, VAL35a, VAL51a, VAL52a, VAL54a, VAL82e, VAL8e, VAL93a, VAL93e
• a-l: ALA6a, ALA6l, ARG40a, ARG40l, ASN7a, ASN7l, ASP36a, ASP36l, GLN43l, GLU146a, GLU146l, LYS5a, LYS5l
• a-m: ARG21m, ARG40a, ASP28a, ASP28m, ASP32a, ASP36a, GLU123a, GLU123m, GLY130a, PHE25m
• b-c: ALA102b, ALA105b, ALA113b, ALA125b, ALA140b, ALA144b, ALA153b, ALA16c, ALA20c, ALA57c, ALA63c, ALA66c, ALA68c, ALA6b, ALA75b, ALA78b, ALA88c, ALA94b, ALA94c, ALA97b, ALA97c, ARG128b, ARG14c, ARG21c, ARG84b, ASN2b, ASN48c, ASN7b, ASN99b, ASN99c, ASP107b, ASP107c, ASP28c, ASP32c, ASP36c, ASP46c, ASP47c, GLN106b, GLN106c, GLN124b, GLN24c, GLU120b, GLU127b, GLU139b, GLU146b, GLU59c, GLU65c, GLU91b, GLU91c, GLY100b, GLY100c, GLY109b, GLY115b, GLY56c, GLY85c, GLY86c, GLY95b, GLY95c, GLY96b, GLY96c, HIS89c, ILE148b, ILE154b, ILE17c, ILE19c, ILE3b, ILE49c, ILE4b, ILE83b, LEU101b, LEU101c, LEU117b, LEU142b, LEU145b, LEU151b, LEU31c, LEU38c, LEU60c, LEU62c, LEU67c, LYS136b, LYS45c, LYS5b, LYS69c, LYS72c, MET147b, MET1b, PHE114b, PHE22c, PHE90b, PHE90c, PRO111b, PRO55c, PRO61c, SER103b, SER103c, SER108b, SER121b, SER70c, SER98b, THR118b, THR119b, THR143b, THR18c, THR39c, THR50c, THR64c, THR87c, TRP53c, TYR58c, TYR73c, TYR92b, TYR92c, VAL104b, VAL104c, VAL110b, VAL112b, VAL116b, VAL150b, VAL15c, VAL35c, VAL51c, VAL52c, VAL54c, VAL82b, VAL8b, VAL93b, VAL93c
• b-l: ARG21b, ARG40l, ASP28b, ASP28l, ASP32l, ASP36l, GLU123b, GLU123l
• c-d: ALA102c, ALA105c, ALA113c, ALA125c, ALA133c, ALA140c, ALA144c, ALA153c, ALA16d, ALA57d, ALA63d, ALA66d, ALA68d, ALA6c, ALA75c, ALA78c, ALA88d, ALA94c, ALA97c, ALA97d, ARG128c, ARG14d, ARG21d, ARG84c, ASN2c, ASN48d, ASN7c, ASN99c, ASN99d, ASP107c, ASP107d, ASP28d, ASP32d, ASP36d, ASP46d, ASP47d, GLN106c, GLN106d, GLN124c, GLN24d, GLU120c, GLU127c, GLU139c, GLU146c, GLU59d, GLU65d, GLU91c, GLU91d, GLY100c, GLY100d, GLY109c, GLY115c, GLY56d, GLY85d, GLY86d, GLY95c, GLY95d, GLY96c, GLY96d, HIS89d, ILE148c, ILE154c, ILE17d, ILE19d, ILE3c, ILE49d, ILE4c, ILE83c, LEU101c, LEU101d, LEU117c, LEU142c, LEU145c, LEU151c, LEU31d, LEU38d, LEU60d, LEU62d, LEU67d, LYS136c, LYS45d, LYS5c, LYS69d, LYS72d, MET147c, MET1c, PHE114c, PHE22d, PHE90c, PHE90d, PRO111c, PRO55d, PRO61d, SER103c, SER103d, SER108c, SER121c, SER70d, SER98c, THR118c, THR119c, THR143c, THR18d, THR39d, THR50d, THR64d, THR87d, TRP53d, TYR58d, TYR73d, TYR92c, TYR92d, VAL104c, VAL104d, VAL110c, VAL112c, VAL116c, VAL150c, VAL15d, VAL35d, VAL51d, VAL52d, VAL54d, VAL82c, VAL8c, VAL93c, VAL93d
• d-e: ALA102d, ALA105d, ALA113d, ALA125d, ALA140d, ALA144d, ALA153d, ALA16e, ALA57e, ALA63e, ALA66e, ALA68e, ALA6d, ALA75d, ALA78d, ALA88e, ALA94d, ALA97d, ALA97e, ARG128d, ARG14e, ARG21e, ARG84d, ASN2d, ASN48e, ASN7d, ASN99d, ASN99e, ASP107d, ASP107e, ASP28e, ASP32e, ASP36e, ASP46e, ASP47e, GLN106d, GLN106e, GLN124d, GLN24e, GLU120d, GLU127d, GLU139d, GLU146d, GLU59e, GLU65e, GLU91d, GLU91e, GLY100d, GLY100e, GLY109d, GLY115d, GLY56e, GLY85e, GLY86e, GLY95d, GLY95e, GLY96d, GLY96e, HIS89e, ILE148d, ILE154d, ILE17e, ILE19e, ILE3d, ILE49e, ILE4d, ILE83d, LEU101d, LEU101e, LEU117d, LEU142d, LEU145d, LEU151d, LEU31e, LEU38e, LEU60e, LEU62e, LEU67e, LYS136d, LYS45e, LYS5d, LYS69e, LYS72e, MET147d, MET1d, PHE114d, PHE22e, PHE90d, PHE90e, PRO111d, PRO55e, PRO61e, SER103d, SER103e, SER108d, SER121d, SER70e, SER98d, THR118d, THR119d, THR143d, THR18e, THR39e, THR50e, THR64e, THR87e, TRP53e, TYR58e, TYR73e, TYR92d, TYR92e, VAL104d, VAL104e, VAL110d, VAL112d, VAL116d, VAL150d, VAL15e, VAL35e, VAL51e, VAL52e, VAL54e, VAL82d, VAL8d, VAL93d, VAL93e
• d-f: ALA125d, ALA125f, ALA129d, ALA133d, ALA138d, ALA34d, ALA37d, ARG128d, ARG21f, ARG40d, ARG84f, ASN135d, ASN23f, ASN27d, ASN27f, ASP28d, ASP28f, ASP32d, ASP36d, GLN124d, GLN124f, GLN24d, GLN24f, GLU120f, GLU123d, GLU123f, GLU127d, GLY130d, GLY134d, GLY33d, GLY85f, GLY86f, ILE122d, ILE122f, ILE126d, ILE126f, ILE26d, ILE26f, ILE41d, ILE83f, LEU30d, LEU31d, LYS132d, PHE22f, PHE25d, PHE25f, PHE90f, PRO55f, SER121f, SER29d, SER29f, THR119f, THR131d, THR131f, THR81f, THR87f, TRP53f, VAL54f, VAL82f
• d-j: ALA133d, ALA133j, ALA37d, ALA37j, ALA6d, ALA6j, ALA9d, ALA9j, ARG128d, ARG128j, ARG40d, ARG40j, ASN149d, ASN7d, ASN7j, ASP32d, ASP32j, ASP36d, ASP36j, GLN43d, GLN43j, GLU146d, GLU146j, GLY33d, GLY33j, GLY42d, GLY42j, ILE41d, ILE41j, ILE4d, ILE4j, LEU142d, LEU142j, LEU38d, LEU38j, LYS132d, LYS132j, LYS5d, LYS5j, PRO11d, PRO11j, THR143d, THR143j, THR39d, THR39j, VAL150d, VAL8d, VAL8j
• e-j: ALA125e, ALA125j, ALA129j, ALA133j, ALA138j, ALA34j, ALA37j, ARG128j, ARG21e, ARG40j, ARG84e, ASN135j, ASN23e, ASN27e, ASN27j, ASP28e, ASP28j, ASP32j, ASP36j, GLN124j, GLN24e, GLN24j, GLU120e, GLU123e, GLU123j, GLU127j, GLY130j, GLY134j, GLY33j, GLY85e, GLY86e, ILE122e, ILE122j, ILE126e, ILE126j, ILE26e, ILE26j, ILE41j, ILE83e, LEU30j, LEU31j, LYS132j, PHE22e, PHE25e, PHE25j, PHE90e, PRO55e, SER121e, SER29j, THR119e, THR131e, THR131j, THR81e, THR87e, TRP53e, VAL54e, VAL82e
• f-g: ALA102f, ALA105f, ALA113f, ALA125f, ALA133f, ALA140f, ALA144f, ALA153f, ALA16g, ALA57g, ALA63g, ALA66g, ALA68g, ALA6f, ALA75f, ALA78f, ALA88g, ALA94f, ALA94g, ALA97f, ALA97g, ARG128f, ARG14g, ARG21g, ARG84f, ASN2f, ASN48g, ASN7f, ASN99f, ASN99g, ASP107f, ASP107g, ASP28g, ASP32g, ASP36g, ASP46g, ASP47g, GLN106f, GLN106g, GLN124f, GLN24g, GLU120f, GLU127f, GLU139f, GLU146f, GLU59g, GLU65g, GLU91f, GLU91g, GLY100f, GLY100g, GLY109f, GLY115f, GLY56g, GLY85g, GLY86g, GLY95f, GLY95g, GLY96f, GLY96g, HIS89f, HIS89g, ILE148f, ILE154f, ILE17g, ILE19g, ILE3f, ILE49g, ILE4f, ILE83f, LEU101f, LEU101g, LEU117f, LEU142f, LEU145f, LEU151f, LEU31g, LEU38g, LEU60g, LEU62g, LEU67g, LYS136f, LYS45g, LYS5f, LYS69g, LYS72g, MET147f, MET1f, PHE114f, PHE22g, PHE90f, PHE90g, PRO111f, PRO55g, PRO61g, SER103f, SER103g, SER108f, SER121f, SER70g, SER98f, THR118f, THR119f, THR143f, THR18g, THR39g, THR50g, THR64g, THR87g, TRP53g, TYR58g, TYR73g, TYR92f, TYR92g, VAL104f, VAL104g, VAL110f, VAL112f, VAL116f, VAL150f, VAL15g, VAL35g, VAL51g, VAL52g, VAL54g, VAL82f, VAL8f, VAL93f, VAL93g
• f-j: ALA102j, ALA105j, ALA113j, ALA125j, ALA133j, ALA140j, ALA144j, ALA16f, ALA57f, ALA63f, ALA66f, ALA6j, ALA75j, ALA78j, ALA88f, ALA94f, ALA94j, ALA97f, ALA97j, ARG128j, ARG14f, ARG21f, ARG84j, ASN2j, ASN48f, ASN7j, ASN99f, ASN99j, ASP107f, ASP107j, ASP28f, ASP32f, ASP36f, ASP46f, ASP47f, GLN106f, GLN106j, GLN124j, GLN24f, GLU120j, GLU127j, GLU139j, GLU146j, GLU59f, GLU65f, GLU91f, GLU91j, GLY100f, GLY100j, GLY109j, GLY115j, GLY56f, GLY85f, GLY86f, GLY95f, GLY95j, GLY96f, GLY96j, HIS89f, HIS89j, ILE17f, ILE19f, ILE3j, ILE49f, ILE4j, ILE83j, LEU101f, LEU101j, LEU117j, LEU142j, LEU145j, LEU31f, LEU38f, LEU62f, LEU67f, LYS136j, LYS45f, LYS5j, LYS69f, LYS72f, MET1j, PHE114j, PHE22f, PHE90f, PHE90j, PRO111j, PRO55f, PRO61f, SER103f, SER103j, SER108j, SER121j, SER98j, THR118j, THR119j, THR143j, THR18f, THR39f, THR50f, THR87f, TRP53f, TYR58f, TYR73f, TYR92f, TYR92j, VAL104f, VAL104j, VAL110j, VAL112j, VAL116j, VAL15f, VAL35f, VAL51f, VAL52f, VAL54f, VAL82j, VAL8j, VAL93f, VAL93j
• g-h: ALA102g, ALA102h, ALA105g, ALA113g, ALA125g, ALA140g, ALA144g, ALA153g, ALA16h, ALA20h, ALA57h, ALA63h, ALA66h, ALA68h, ALA6g, ALA75g, ALA78g, ALA88h, ALA94g, ALA97g, ALA97h, ARG128g, ARG14h, ARG21h, ARG84g, ASN149g, ASN2g, ASN48h, ASN7g, ASN99g, ASN99h, ASP107g, ASP107h, ASP28h, ASP32h, ASP36h, ASP46h, ASP47h, ASP74g, GLN106g, GLN106h, GLN124g, GLN24h, GLU120g, GLU127g, GLU139g, GLU146g, GLU59h, GLU65h, GLU91g, GLU91h, GLY100g, GLY100h, GLY109g, GLY115g, GLY56h, GLY85h, GLY86h, GLY95g, GLY95h, GLY96g, GLY96h, HIS89h, ILE148g, ILE154g, ILE17h, ILE19h, ILE3g, ILE49h, ILE4g, ILE83g, LEU101g, LEU101h, LEU117g, LEU142g, LEU145g, LEU151g, LEU31h, LEU38h, LEU60h, LEU62h, LEU67h, LYS136g, LYS152g, LYS45h, LYS5g, LYS69h, LYS72h, MET147g, MET1g, PHE114g, PHE22h, PHE90g, PHE90h, PRO111g, PRO55h, PRO61h, SER103g, SER103h, SER108g, SER121g, SER70h, SER98g, THR118g, THR119g, THR143g, THR18h, THR39h, THR50h, THR64h, THR87h, TRP53h, TYR58h, TYR73h, TYR92g, TYR92h, VAL104g, VAL104h, VAL110g, VAL112g, VAL116g, VAL150g, VAL15h, VAL35h, VAL51h, VAL52h, VAL54h, VAL82g, VAL8g, VAL93g, VAL93h
• h-i: ALA102h, ALA102i, ALA105h, ALA113h, ALA125h, ALA140h, ALA144h, ALA153h, ALA16i, ALA57i, ALA63i, ALA66i, ALA68i, ALA6h, ALA75h, ALA78h, ALA88i, ALA94h, ALA97h, ALA97i, ARG128h, ARG14i, ARG21i, ARG84h, ASN149h, ASN2h, ASN48i, ASN7h, ASN99h, ASN99i, ASP107h, ASP107i, ASP28i, ASP32i, ASP36i, ASP46i, ASP47i, ASP74h, GLN106h, GLN106i, GLN124h, GLN24i, GLU120h, GLU127h, GLU139h, GLU146h, GLU59i, GLU65i, GLU91h, GLU91i, GLY100h, GLY100i, GLY109h, GLY115h, GLY56i, GLY85i, GLY86i, GLY95h, GLY95i, GLY96h, GLY96i, HIS89i, ILE148h, ILE154h, ILE17i, ILE19i, ILE3h, ILE49i, ILE4h, ILE83h, LEU101h, LEU101i, LEU117h, LEU142h, LEU145h, LEU151h, LEU31i, LEU38i, LEU60i, LEU62i, LEU67i, LYS136h, LYS45i, LYS5h, LYS69i, LYS72i, MET147h, MET1h, PHE114h, PHE22i, PHE90h, PHE90i, PRO111h, PRO55i, PRO61i, SER103h, SER103i, SER108h, SER121h, SER70i, SER98h, THR118h, THR119h, THR143h, THR18i, THR39i, THR50i, THR64i, THR87i, TRP53i, TYR58i, TYR73i, TYR92h, TYR92i, VAL104h, VAL104i, VAL110h, VAL112h, VAL116h, VAL150h, VAL15i, VAL35i, VAL51i, VAL52i, VAL54i, VAL82h, VAL8h, VAL93h, VAL93i
• i-j: ALA102i, ALA102j, ALA105i, ALA113i, ALA125i, ALA140i, ALA144i, ALA153i, ALA16j, ALA57j, ALA63j, ALA66j, ALA68j, ALA6i, ALA75i, ALA78i, ALA88j, ALA94i, ALA97i, ALA97j, ARG128i, ARG14j, ARG21j, ARG84i, ASN2i, ASN48j, ASN7i, ASN99i, ASN99j, ASP107i, ASP107j, ASP28j, ASP32j, ASP36j, ASP46j, ASP47j, ASP74i, GLN106i, GLN106j, GLN124i, GLN24j, GLU120i, GLU127i, GLU139i, GLU146i, GLU59j, GLU65j, GLU91i, GLU91j, GLY100i, GLY100j, GLY109i, GLY115i, GLY56j, GLY85j, GLY86j, GLY95i, GLY95j, GLY96i, GLY96j, HIS89j, ILE148i, ILE154i, ILE17j, ILE19j, ILE3i, ILE49j, ILE4i, ILE83i, LEU101i, LEU101j, LEU117i, LEU142i, LEU145i, LEU151i, LEU31j, LEU38j, LEU60j, LEU62j, LEU67j, LYS136i, LYS45j, LYS5i, LYS69j, LYS72j, MET147i, MET1i, PHE114i, PHE22j, PHE90i, PHE90j, PRO111i, PRO55j, PRO61j, SER103i, SER103j, SER108i, SER121i, SER70j, SER98i, THR118i, THR119i, THR143i, THR18j, THR39j, THR50j, THR64j, THR87j, TRP53j, TYR58j, TYR73j, TYR92i, TYR92j, VAL104i, VAL104j, VAL110i, VAL112i, VAL116i, VAL150i, VAL15j, VAL35j, VAL51j, VAL52j, VAL54j, VAL82i, VAL8i, VAL93i, VAL93j
• k-l: ARG128k, ARG21l, ASN2k, ASP107k, GLN106k, GLU146k, GLU59l, GLU65l, GLU91k, GLU91l, HIS89l, ILE49l, ILE4k, LYS136k, LYS5k, SER103l, SER98k, TYR58l, VAL51l
• k-o: ARG128o, ARG21k, ASN2o, ASP107o, GLN124o, GLU146o, GLU59k, GLU65k, GLU91k, GLU91o, GLY86k, HIS89k, ILE49k, ILE4o, LYS136o, LYS5o, TRP53k, VAL51k
• k-x: ARG21k, ARG40x, ASP28k, ASP32x, ASP36x, GLU123k, GLU123x, GLY130x, PHE25k
• l-m: ARG128l, ARG21m, ASN2l, GLN106l, GLU146l, GLU59m, GLU91l, GLU91m, HIS89m, ILE49m, ILE4l, LYS136l, LYS5l, SER103m, TRP53m, VAL51m
• m-n: ALA88n, ARG128m, ARG21n, ASN2m, ASP107m, GLN106m, GLN124m, GLU146m, GLU59n, GLU65n, GLU91m, GLU91n, GLY86n, HIS89n, ILE49n, ILE4m, LYS136m, LYS5m, SER103n, THR118m, TRP53n, VAL51n
• n-o: ARG128n, ARG21o, ASN2n, ASP107n, GLN106n, GLU146n, GLU59o, GLU65o, GLU91n, GLU91o, HIS89o, ILE49o, ILE4n, LYS136n, LYS5n, SER103o, TRP53o, VAL51o
• n-p: ARG21p, ARG40n, ASP28n, ASP28p, ASP32n, ASP36n, GLU123n, GLU123p, GLY130n, PHE25p
• n-t: ALA6n, ALA6t, ARG40n, ARG40t, ASN7n, ASN7t, ASP36n, ASP36t, GLU146n, GLU146t, LYS5n, LYS5t
• o-t: ARG21o, ARG40t, ASP28o, ASP28t, ASP32t, ASP36t, GLU123o, GLU123t, GLY130t, PHE25o
• o-x: ALA6o, ALA6x, ARG40o, ARG40x, ASN7o, ASN7x, ASP36o, ASP36x, GLU146o, GLU146x, LYS5o, LYS5x
• o-y: ARG21y, ARG40o, ASP28y, ASP32o, ASP36o, GLU123o, GLU123y, GLY130o, PHE25y
• p-q: ARG128p, ARG21q, ASN2p, ASP107p, GLN106p, GLU146p, GLU59q, GLU65q, GLU91p, GLU91q, HIS89q, ILE49q, ILE4p, LYS136p, LYS5p, SER103q, TRP53q, VAL51q
• p-t: ARG128t, ARG21p, ASN2t, GLN124t, GLU146t, GLU59p, GLU91p, GLU91t, GLY86p, HIS89p, ILE49p, ILE4t, LYS136t, LYS5t, TRP53p, VAL51p
• q-r: ARG128q, ARG21-6.3905182.814660, ARG21r, ASN2q, ASP107q, GLN106q, GLU146q, GLU59r, GLU65r, GLU91q, GLU91r, HIS89r, ILE49-4.1636682.995266, ILE4q, LYS136q, LYS5q, SER103-6.2382323.157900, TRP53-9.9028223.067654, VAL51-15.8725182.669544, VAL51-7.4502123.149960
• r-s: 2-3.2936823.204334ASN, 2-7.8604973.196993ASN, 4-14.0884852.800768ILE, 4-9.0529843.130083ILE, ARG128r, ARG21s, ASP107r, GLN106-6.5856363.140528, GLU146-5.4698242.949869, GLU146r, GLU59s, GLU65s, GLU91r, GLU91s, HIS89s, LYS136r, LYS5r
• s-t: ALA88t, ARG128s, ARG21t, ASN2s, ASP107s, GLN106s, GLN124s, GLU146s, GLU59t, GLU65t, GLU91s, GLU91t, GLY86t, HIS89t, ILE49t, ILE4s, LYS136s, LYS5s, SER103t, THR118s, TRP53t, VAL51t
• s-u: ARG21u, ARG40s, ASP28s, ASP28u, ASP32s, ASP36s, GLU123s, GLU123u, GLY130s, PHE25u
• s-y: ALA6s, ALA6y, ARG40s, ARG40y, ASN7s, ASN7y, ASP36s, ASP36y, GLU146s, GLU146y, LYS5s, LYS5y
• t-y: ARG21t, ARG40y, ASP28t, ASP28y, ASP32y, ASP36y, GLU123t, GLU123y, GLY130y, PHE25t
• u-v: ARG128u, ARG21v, ASN2u, ASP107u, GLN106u, GLU146u, GLU59v, GLU65v, GLU91u, GLU91v, HIS89v, ILE49v, ILE4u, LYS136u, LYS5u, SER103v, TRP53v, VAL51v
• u-y: ARG128y, ARG21u, ASN2y, ASP107y, GLN124y, GLU146y, GLU59u, GLU65u, GLU91u, GLU91y, GLY86u, HIS89u, ILE49u, ILE4y, LYS136y, LYS5y, TRP53u, VAL51u
• v-w: ALA88w, ARG128v, ARG21w, ASN2v, ASP107v, GLN106v, GLN124v, GLU146v, GLU59w, GLU65w, GLU91v, GLU91w, GLY86w, HIS89w, ILE49w, ILE4v, LYS136v, LYS5v, SER103w, THR118v, TRP53w, VAL51w
• w-x: ARG128w, ARG21x, ASN2w, GLN106w, GLN124w, GLU146w, GLU59x, GLU91w, GLU91x, GLY86x, HIS89x, ILE4w, LYS136w, LYS5w, SER103x, TRP53x, VAL51x
• x-y: ARG128x, ARG21y, ASN2x, GLN106x, GLN124x, GLU146x, GLU59y, GLU91x, GLU91y, GLY86y, HIS89y, ILE49y, ILE4x, LYS136x, LYS5x, SER103y, TRP53y, VAL51y