3MJH

crystal structure of human rab5a in complex with the c2h2 zinc finger of eea1

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 63
  • Norm. En. per Res.: -3.91
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.0055	18.8381	-164.682	-185.8493	59	6	3	5979	0	7	6
A-C	0.0	-22.3153	-45.9292	-68.2445	42	4	0	2224	0	21	14
B-C	-9.8667	12.784	-101.519	-98.6016	33	10	2	2764	0	19	13
B-D	0.0	6.323	-0.0008	6.3222	4	0	0	2	0	1	2
C-D	-56.0621	-10.1411	-180.124	-246.3273	63	8	6	6300	1	8	6

Interface residues

• A-B: ALA53B, ALA55A, ALA56A, ALA66B, ALA77A, ALA86A, ARG81A, ARG91A, ASP54B, ASP65B, ASP75A, CYS43B, CYS46B, GLN45B, GLN49A, GLU39B, GLU50A, GLU55B, GLU61B, GLU72A, GLY40B, GLY51B, GLY54A, GLY92A, HIS59B, HIS64B, HIS83A, ILE42B, ILE53A, ILE73A, LEU50B, LEU56B, LEU58A, LEU85A, LYS22A, LYS48B, LYS58B, MET47B, MET88A, PHE41B, PHE57A, PHE57B, PRO44B, PRO87A, SER34A, SER37B, SER38B, SER49B, SER51A, SER52B, SER84A, THR52A, THR59A, THR76A, TRP74A, TYR60B, TYR82A, TYR89A, TYR90A
• A-C: ALA122A, ALA142C, ALA30C, ALA86A, ARG120A, ARG81A, ARG81C, ARG91A, ASN104C, ASP101C, GLN119A, GLN121A, GLN49C, GLU105C, GLU106C, GLU47C, GLU50C, GLU80A, GLY92A, HIS83A, ILE53C, LEU137C, LEU79A, LEU79C, LEU85A, LYS116A, LYS134C, LYS140C, LYS22A, MET88A, PHE48C, PRO124A, PRO87A, SER29C, SER51C, SER84A, THR103C, THR52C, TYR82A, TYR82C, TYR89A, TYR90A
• B-C: ALA164C, ALA53B, ALA62B, ALA66B, ARG39C, ASN68B, ASP54B, ASP65B, ASP69B, GLN44C, GLN45B, GLN49C, GLU47C, GLU50C, GLU55B, GLU61B, GLY43C, HIS46C, HIS64B, ILE53C, LEU38C, LEU56B, LYS165C, LYS42C, LYS58B, PHE41B, PHE45C, PHE48C, PHE57B, PRO44B, SER51C, SER52B, TYR60B
• B-D: ASP54B, GLU39D, LYS58B, SER37D
• C-D: ALA53D, ALA55C, ALA56C, ALA66D, ALA77C, ALA86C, ALA93C, ARG81C, ARG91C, ASP54D, ASP65D, ASP69D, ASP75C, CYS43D, CYS46D, GLN45D, GLN49C, GLU39D, GLU50C, GLU55D, GLU61D, GLU72C, GLY40D, GLY54C, GLY67D, GLY92C, HIS59D, HIS64D, ILE42D, ILE53C, ILE73C, LEU50D, LEU56D, LEU58C, LEU85C, LYS22C, LYS42C, LYS48D, LYS58D, MET47D, MET88C, PHE41D, PHE57C, PHE57D, PRO44D, PRO87C, SER34C, SER37D, SER38D, SER49D, SER51C, SER52D, SER84C, THR52C, THR59C, THR76C, TRP74C, TYR60D, TYR82C, TYR89C, TYR90C, VAL24C, VAL63D