3MJG

the structure of a platelet derived growth factor receptor complex

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-X
  • Int. Res.: 82
  • Norm. En. per Res.: -4.5692
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-103.0333	-69.719	1104.31	931.5576	107	30	15	12213	5	22	24
A-X	-22.6818	-36.1213	-112.231	-171.034	48	4	0	4532	2	20	22
A-Y	-38.5128	-42.9318	-237.256	-318.7005	87	31	10	10558	0	33	20
B-X	-60.7316	-49.2	-264.742	-374.6736	82	16	11	10603	3	34	17
B-Y	-48.8275	-55.2416	-105.258	-209.3271	51	14	0	4655	2	17	18

Interface residues

• A-B: ALA11A, ALA11B, ALA14A, ALA14B, ALA87A, ALA87B, ALA8A, ALA8B, ARG19A, ARG19B, ARG27A, ARG27B, ARG56A, ARG56B, ARG68A, ARG68B, ARG73A, ARG73B, ASN54A, ASN54B, ASN55A, ASN55B, CYS16A, CYS16B, CYS43A, CYS43B, CYS49A, CYS49B, CYS52A, CYS52B, CYS53A, CYS53B, CYS60A, GLN47A, GLN47B, GLN66A, GLN66B, GLN71A, GLN71B, GLU15A, GLU15B, GLU21A, GLU21B, GLU24A, GLU24B, GLU45A, GLU45B, GLU9A, GLU9B, GLY51A, GLY51B, ILE13A, ILE13B, ILE25A, ILE25B, ILE7A, ILE7B, LEU38A, LEU38B, LEU67B, LEU91A, LEU91B, LYS17A, LYS17B, LYS86A, LYS86B, MET12A, MET12B, PHE23A, PHE23B, PRO10A, PRO10B, PRO41A, PRO41B, PRO42A, PRO42B, PRO69A, PRO69B, SER26A, SER26B, SER50A, SER50B, THR18A, THR18B, THR20A, THR20B, THR6A, THR6B, THR88A, THR88B, THR90B, TRP40A, TRP40B, VAL22A, VAL22B, VAL39A, VAL39B, VAL44A, VAL44B, VAL46A, VAL46B, VAL70A, VAL70B, VAL72A, VAL72B, VAL89A, VAL89B
• A-X: ALA14A, ALA203X, ARG186X, ARG208X, ARG56A, ASN54A, ASN55A, ASN57A, ASP185X, ASP267X, CYS16A, CYS53A, CYS97A, CYS99A, GLN210X, GLN59A, GLU100A, GLU15A, GLU162X, GLU184X, GLU241X, ILE137X, ILE13A, ILE142X, LEU135X, LEU139X, LEU209X, LEU266X, LYS163X, LYS164X, LYS17A, LYS98A, MET12A, MET268X, PHE136X, PHE138X, PHE264X, PRO269X, SER187X, THR101A, TYR188X, TYR204X, TYR205X, TYR207X, TYR270X, VAL102A, VAL206X, VAL58A
• A-Y: ALA132Y, ALA35A, ARG186Y, ARG208Y, ARG273Y, ARG27A, ARG28A, ARG32A, ARG73A, ARG79A, ASN240Y, ASN244Y, ASN292Y, ASN298Y, ASN34A, ASN36A, ASP131Y, ASP185Y, ASP263Y, ASP267Y, ASP299Y, ASP31A, GLN210Y, GLN71A, GLU133Y, GLU134Y, GLU141Y, GLU144Y, GLU241Y, GLU246Y, GLU24A, GLU259Y, GLU295Y, GLU76A, ILE137Y, ILE145Y, ILE272Y, ILE275Y, ILE30A, ILE75A, ILE77A, ILE83A, LEU135Y, LEU139Y, LEU209Y, LEU29A, LEU38A, LYS163Y, LYS80A, LYS81A, LYS86A, PHE136Y, PHE138Y, PHE245Y, PHE264Y, PHE37A, PHE84A, PRO260Y, PRO41A, PRO42A, PRO82A, SER187Y, SER26A, SER274Y, SER296Y, THR140Y, THR143Y, THR262Y, THR294Y, THR33A, TRP247Y, TRP40A, TYR204Y, TYR205Y, TYR207Y, TYR270Y, VAL206Y, VAL211Y, VAL237Y, VAL242Y, VAL243Y, VAL258Y, VAL261Y, VAL293Y, VAL297Y, VAL39A, VAL78A
• B-X: ALA132X, ALA203X, ALA35B, ARG186X, ARG208X, ARG273X, ARG27B, ARG28B, ARG32B, ARG73B, ARG79B, ASN240X, ASN244X, ASN298X, ASN34B, ASN36B, ASP131X, ASP185X, ASP263X, ASP267X, ASP299X, ASP31B, GLN210X, GLU133X, GLU134X, GLU141X, GLU241X, GLU246X, GLU24B, GLU259X, GLU295X, GLU76B, ILE137X, ILE272X, ILE275X, ILE30B, ILE75B, ILE77B, ILE83B, LEU135X, LEU139X, LEU209X, LEU29B, LEU38B, LYS163X, LYS80B, LYS81B, LYS86B, PHE136X, PHE138X, PHE245X, PHE264X, PHE37B, PHE84B, PRO260X, PRO41B, PRO42B, PRO82B, SER187X, SER26B, SER274X, SER296X, THR140X, THR143X, THR262X, THR294X, THR33B, TRP247X, TRP40B, TYR205X, TYR207X, TYR270X, VAL206X, VAL237X, VAL242X, VAL243X, VAL258X, VAL261X, VAL293X, VAL297X, VAL39B, VAL78B
• B-Y: ALA11B, ALA132Y, ALA14B, ALA203Y, ARG186Y, ARG208Y, ARG56B, ARG61B, ASN54B, ASN55B, ASN57B, ASP185Y, ASP267Y, CYS16B, CYS52B, CYS53B, CYS97B, CYS99B, GLN210Y, GLN59B, GLU100B, GLU15B, GLU162Y, GLU184Y, GLU241Y, GLY165Y, ILE137Y, ILE13B, LEU139Y, LEU209Y, LEU266Y, LYS163Y, LYS164Y, LYS17B, LYS98B, MET12B, MET268Y, PHE136Y, PHE138Y, PRO10B, PRO269Y, SER187Y, THR101B, TYR188Y, TYR204Y, TYR205Y, TYR207Y, TYR270Y, VAL102B, VAL206Y, VAL58B