3MDY

crystal structure of the cytoplasmic domain of the bone morphogenetic protein receptor type-1b (bmpr1b) in complex with fkbp12 and ldn- 193189

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 96
  • Norm. En. per Res.: -2.6526
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	0.0	0.0	-26.0172	-26.0172	28	0	0	1173	0	0	3
A-B	-15.369	-0.8428	-238.436	-254.6478	96	8	4	10072	1	18	17
A-D	-5.1164	10.7867	-109.649	-103.9788	43	5	0	3361	0	5	6
C-B	-5.5623	10.676	-112.918	-107.8044	44	4	0	3458	0	4	6
C-D	-10.7848	2.8807	-230.544	-238.4481	94	6	4	9635	0	18	17

Interface residues

• A-C: ALA201A, ALA201C, ARG198A, ARG198C, ASP265A, ASP265C, GLN274A, GLN274C, GLY268A, GLY268C, GLY270A, GLY270C, ILE266A, ILE266C, LEU275A, LEU275C, LYS202A, LYS202C, LYS267A, LYS267C, SER271A, SER271C, THR269A, THR269C, THR273A, THR273C, TRP272A, TRP272C
• A-B: ALA239A, ALA263A, ALA264A, ALA82B, ALA85B, ARG198A, ARG224A, ARG243A, ARG41B, ARG43B, ASN44B, ASP178A, ASP265A, ASP38B, ASP42B, GLN182A, GLN184A, GLN197A, GLN203A, GLN249A, GLN54B, GLU174A, GLU181A, GLU238A, GLU244A, GLU246A, GLU55B, GLU61B, GLY187A, GLY189A, GLY191A, GLY29B, GLY52B, GLY84B, GLY87B, GLY90B, HIS88B, ILE180A, ILE200A, ILE247A, ILE266A, ILE278A, ILE57B, ILE77B, ILE91B, ILE92B, LEU179A, LEU192A, LEU194A, LEU195A, LEU275A, LEU277A, LEU31B, LEU98B, LYS202A, LYS356A, LYS36B, LYS45B, LYS48B, LYS53B, MET50B, PHE100B, PHE242A, PHE261A, PHE37B, PHE47B, PHE49B, PRO193A, PRO89B, PRO93B, PRO94B, SER175A, SER183A, SER185A, SER186A, SER188A, SER190A, SER39B, SER40B, THR199A, THR235A, THR245A, THR250A, THR273A, THR28B, THR86B, TRP241A, TRP60B, TYR248A, TYR276A, TYR27B, TYR83B, VAL102B, VAL196A, VAL25B, VAL56B
• A-D: ALA82D, ALA85D, ARG19D, ARG58D, ASP80D, GLN274A, GLN54D, GLU237A, GLU238A, GLU55D, GLU61D, GLU62D, GLY268A, GLY270A, GLY2D, GLY52D, GLY59D, GLY84D, ILE57D, ILE77D, LEU51D, LYS267A, LYS53D, MET50D, PHE233A, PHE234A, PHE49D, PRO79D, SER0D, SER271A, SER78D, THR235A, THR236A, THR269A, THR273A, THR86D, TRP219A, TRP272A, TRP60D, TYR81D, TYR83D, VAL3D, VAL56D
• C-B: ALA65B, ALA82B, ALA85B, ARG19B, ARG58B, ASP80B, GLN274C, GLN54B, GLU237C, GLU238C, GLU55B, GLU61B, GLU62B, GLY268C, GLY270C, GLY2B, GLY52B, GLY59B, GLY84B, ILE57B, ILE77B, LEU51B, LYS267C, LYS53B, MET1B, PHE233C, PHE234C, PHE49B, PRO79B, SER0B, SER271C, SER78B, THR235C, THR236C, THR269C, THR273C, THR86B, TRP219C, TRP272C, TRP60B, TYR81B, TYR83B, VAL3B, VAL56B
• C-D: ALA239C, ALA263C, ALA264C, ALA82D, ALA85D, ARG198C, ARG224C, ARG243C, ARG41D, ARG43D, ASN44D, ASP178C, ASP265C, ASP38D, ASP42D, GLN182C, GLN184C, GLN197C, GLN203C, GLN249C, GLN54D, GLU174C, GLU181C, GLU238C, GLU244C, GLU246C, GLU55D, GLU61D, GLY187C, GLY189C, GLY191C, GLY29D, GLY52D, GLY84D, GLY87D, GLY90D, HIS88D, ILE180C, ILE200C, ILE247C, ILE266C, ILE278C, ILE57D, ILE77D, ILE91D, ILE92D, LEU179C, LEU192C, LEU194C, LEU195C, LEU275C, LEU277C, LEU31D, LEU98D, LYS202C, LYS36D, LYS45D, LYS48D, LYS53D, MET50D, PHE100D, PHE242C, PHE261C, PHE37D, PHE47D, PHE49D, PRO193C, PRO89D, PRO93D, PRO94D, SER175C, SER183C, SER185C, SER186C, SER188C, SER190C, SER39D, SER40D, THR199C, THR235C, THR245C, THR250C, THR273C, THR28D, THR86D, TRP241C, TRP60D, TYR276C, TYR27D, TYR83D, VAL102D, VAL196C, VAL25D, VAL56D