3MAP

crystal structure of homodimeric r132h mutant of human cytosolic nadp(+)-dependent isocitrate dehydrogenase in complex with nadp and isocitrate

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 193
  • Norm. En. per Res.: -5.5109
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-248.4254	12.0088	-827.181	-1063.5976	193	74	35	29834	0	55	50

Interface residues

• A-B: ALA141A, ALA141B, ALA179A, ALA179B, ALA256A, ALA256B, ALA258A, ALA282A, ALA282B, ALA378B, ARG119A, ARG140A, ARG140B, ARG222A, ARG222B, ARG314A, ARG314B, ASN171A, ASN171B, ASN184A, ASN184B, ASN213A, ASN213B, ASN271A, ASN271B, ASN385A, ASP143A, ASP143B, ASP160A, ASP160B, ASP186A, ASP186B, ASP220A, ASP220B, ASP225A, ASP252A, ASP252B, ASP253A, ASP253B, ASP79B, CYS379A, CYS379B, GLN163A, GLN163B, GLN185A, GLN185B, GLN283A, GLN283B, GLU153A, GLU153B, GLU173A, GLU173B, GLU174A, GLU174B, GLU190A, GLU190B, GLY123A, GLY123B, GLY148A, GLY148B, GLY150A, GLY150B, GLY161A, GLY161B, GLY175A, GLY175B, GLY176A, GLY176B, GLY177A, GLY177B, GLY181A, GLY181B, GLY221A, GLY221B, GLY284A, GLY284B, GLY286A, GLY286B, GLY382A, GLY382B, HIS133A, HIS133B, HIS170A, HIS170B, HIS315B, ILE154A, ILE154B, ILE189A, ILE189B, ILE215A, ILE215B, ILE226A, ILE226B, ILE251A, ILE251B, ILE380A, LEU120A, LEU120B, LEU168A, LEU168B, LEU216A, LEU216B, LEU288A, LEU288B, LEU383A, LEU383B, LYS151A, LYS151B, LYS164A, LYS164B, LYS187A, LYS187B, LYS212A, LYS212B, LYS217A, LYS217B, LYS218A, LYS218B, LYS260A, LYS260B, LYS270A, LYS270B, LYS381A, MET180A, MET180B, MET182A, MET182B, MET259A, MET259B, PHE144A, PHE144B, PHE172A, PHE172B, PHE223A, PHE223B, PRO147A, PRO147B, PRO149A, PRO149B, PRO158A, PRO158B, PRO384A, PRO384B, SER122A, SER122B, SER159A, SER159B, SER188A, SER188B, THR142A, THR142B, THR155A, THR155B, THR157A, THR157B, THR162A, THR166A, THR166B, THR214A, THR214B, TRP124B, TRP267A, TRP267B, TYR156A, TYR156B, TYR167A, TYR167B, TYR183A, TYR183B, TYR219A, TYR219B, TYR272B, TYR285A, TYR285B, VAL121A, VAL121B, VAL145A, VAL145B, VAL146A, VAL146B, VAL152A, VAL152B, VAL165A, VAL165B, VAL169A, VAL169B, VAL178A, VAL178B, VAL255A, VAL255B, VAL281A, VAL281B, VAL312B