3M4W

structural basis for the negative regulation of bacterial stress response by rseb

• Total interactions analyzed: 28
• Total true interactions: 16
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 83
  • Norm. En. per Res.: -5.605
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-75.515	-115.0344	-270.649	-461.1984	83	12	10	10346	5	28	31
A-D	-9.3717	61.4637	-87.2685	-35.1765	63	4	0	3465	3	48	33
A-E	-63.9106	-131.5301	-468.028	-663.4687	166	42	13	20920	10	42	36
A-F	0.0	0.0	-0.0413	-0.0413	5	0	0	25	0	2	1
A-G	0.0	0.0	-65.7796	-65.7796	31	7	2	2784	0	1	0
B-C	-12.6181	47.5068	-88.0108	-53.122	63	3	0	3458	4	48	35
B-D	-82.1274	-111.5049	-271.579	-465.2113	83	14	10	10186	3	28	30
B-E	0.0	-1.9791	-0.2544	-2.2335	4	0	0	63	0	2	1
B-F	-92.8768	-160.5886	-465.175	-718.6404	167	35	13	20736	11	41	36
B-H	-4.5107	0.0	-62.2291	-66.7398	32	4	2	2578	0	0	0
C-E	-3.5619	0.0	-79.9028	-83.4647	35	1	2	2936	0	2	1
C-G	-50.2431	-141.0936	-396.75	-588.0867	148	28	11	17907	10	33	31
D-F	0.0	0.0	-77.3477	-77.3477	36	3	2	2975	0	1	4
D-H	-14.7031	-100.2643	-319.448	-434.4154	124	22	10	14904	7	29	19
E-G	0.0	0.0	-10.5437	-10.5437	8	1	1	447	0	0	0
F-H	0.0	0.0	-8.0243	-8.0243	9	2	1	452	0	0	0

Interface residues

• A-C: ALA137A, ALA137C, ALA187A, ALA187C, ARG135A, ARG135C, ARG139A, ARG139C, ARG169A, ARG169C, ARG184A, ARG184C, ARG59A, ARG59C, ARG61A, ARG61C, ARG80A, ARG80C, ARG81A, ARG81C, ASN189A, ASN189C, ASP138A, ASP138C, ASP77A, ASP77C, CYS141A, GLN182A, GLN182C, GLN72A, GLN72C, GLN75A, GLN75C, GLU44A, GLU44C, GLU56A, GLU56C, GLU82A, GLU82C, GLY54A, GLY54C, GLY78A, GLY78C, ILE136A, ILE136C, ILE186A, ILE186C, ILE48A, ILE48C, ILE50A, ILE50C, LEU45A, LEU45C, LEU58A, LEU58C, LEU74A, LEU74C, MET168A, MET168C, MET76A, MET76C, PHE188A, PHE188C, PHE47A, PHE47C, PRO79A, PRO79C, PRO95A, PRO95C, SER46A, SER46C, SER49A, SER49C, SER57A, SER57C, THR134A, THR134C, TRP159A, TRP159C, VAL185A, VAL185C, VAL55A, VAL55C
• A-D: ALA148D, ALA305A, ARG145A, ARG145D, ARG149A, ARG149D, ARG153A, ARG153D, ARG175A, ARG175D, ARG278A, ARG278D, ARG307A, ARG307D, ASP127A, ASP150A, ASP150D, ASP174A, ASP174D, ASP176A, ASP176D, ASP274A, ASP274D, GLN275A, GLN303A, GLN303D, GLU178A, GLU178D, GLU310A, GLY151A, GLY151D, GLY177A, GLY177D, ILE129A, ILE129D, LEU173D, LEU180A, LEU180D, LEU300A, LYS306A, LYS306D, LYS52A, LYS52D, MET276A, MET276D, PRO301A, PRO301D, PRO302A, PRO302D, SER155A, SER155D, THR152A, THR152D, THR283A, THR283D, THR304A, THR304D, TYR154A, TYR154D, VAL131A, VAL131D, VAL147A, VAL147D
• A-E: ALA145E, ALA175E, ALA268A, ARG121A, ARG170E, ARG171E, ARG172E, ARG184E, ARG185E, ARG239A, ARG252A, ARG267A, ARG278A, ARG281A, ARG282A, ARG59A, ARG80A, ARG81A, ASN103A, ASN137E, ASN174E, ASN264A, ASN266A, ASN35A, ASN51A, ASP105A, ASP109A, ASP118A, ASP179E, ASP274A, ASP77A, GLN169E, GLN178E, GLN182A, GLN183E, GLN190E, GLN275A, GLN39A, GLN53A, GLN75A, GLN85A, GLU132E, GLU181A, GLU181E, GLU189E, GLU216A, GLU250A, GLU293A, GLU299A, GLU56A, GLU82A, GLU94A, GLU98A, GLY104A, GLY143E, GLY215A, GLY257A, GLY298A, GLY54A, GLY78A, HIS187E, ILE107A, ILE115A, ILE173E, ILE249A, ILE294A, ILE296A, ILE48A, ILE50A, ILE90A, LEU102A, LEU111A, LEU139E, LEU150E, LEU172A, LEU177E, LEU182E, LEU186E, LEU209A, LEU210A, LEU253A, LEU258A, LEU277A, LEU300A, LEU36A, LEU58A, LEU73A, LEU74A, LEU97A, LYS144E, LYS217A, LYS52A, MET141E, MET142E, MET176E, MET247A, MET276A, MET76A, PHE100A, PHE136E, PHE183A, PHE231A, PHE259A, PHE261A, PHE47A, PHE93A, PRO112A, PRO134E, PRO140E, PRO147E, PRO213A, PRO248A, PRO69A, PRO79A, PRO95A, PRO99A, SER110A, SER113A, SER146E, SER149E, SER188E, SER211A, SER235A, SER236A, SER237A, SER251A, SER255A, SER260A, SER262A, SER271A, SER272A, SER285A, SER287A, SER38A, SER49A, SER57A, SER91A, THR101A, THR117A, THR133E, THR138E, THR269A, THR273A, THR279A, THR283A, THR286A, THR295A, TYR106A, TYR116A, TYR156A, TYR180E, TYR254A, TYR92A, VAL108A, VAL135E, VAL148E, VAL212A, VAL214A, VAL234A, VAL263A, VAL265A, VAL284A, VAL288A, VAL297A, VAL55A, VAL83A
• A-F: ARG278A, GLU132F, LEU277A, LYS52A, THR133F
• A-G: ALA137A, ARG135A, ARG169A, ARG184A, ASN137G, ASN51A, ASP171A, GLN182A, GLN53A, GLU178A, GLU181A, GLY280A, GLY54A, ILE136A, ILE48A, ILE50A, LEU139G, LEU172A, LEU173A, LEU180A, LYS52A, PHE136G, PHE183A, PRO140G, SER49A, THR134A, THR138G, THR179A, TRP159A, VAL135G, VAL55A
• B-C: ALA148B, ALA148C, ALA305B, ARG145B, ARG145C, ARG149B, ARG149C, ARG153B, ARG153C, ARG175B, ARG175C, ARG278B, ARG278C, ARG307B, ARG307C, ASP127C, ASP150B, ASP150C, ASP174B, ASP174C, ASP176B, ASP176C, ASP274B, ASP274C, GLN275B, GLN275C, GLN303B, GLN303C, GLU178B, GLU178C, GLU310B, GLU310C, GLY151B, GLY151C, GLY177B, GLY177C, ILE129B, ILE129C, LEU180B, LEU180C, LEU300B, LYS306B, LYS306C, LYS52C, MET276B, MET276C, PRO301B, PRO301C, PRO302B, PRO302C, SER155C, THR152B, THR152C, THR283B, THR283C, THR304B, THR304C, TYR154B, TYR154C, VAL131B, VAL131C, VAL147B, VAL147C
• B-D: ALA137B, ALA137D, ALA187B, ALA187D, ARG135B, ARG135D, ARG139B, ARG139D, ARG169B, ARG169D, ARG184B, ARG184D, ARG59B, ARG59D, ARG61B, ARG61D, ARG80B, ARG80D, ARG81B, ARG81D, ASN189B, ASN189D, ASP138B, ASP138D, ASP77B, ASP77D, CYS141B, GLN182B, GLN182D, GLN72B, GLN72D, GLN75B, GLN75D, GLU44B, GLU44D, GLU56B, GLU56D, GLU82B, GLU82D, GLY54B, GLY54D, GLY78B, GLY78D, ILE136B, ILE136D, ILE186B, ILE186D, ILE48B, ILE48D, ILE50B, ILE50D, LEU45B, LEU45D, LEU58B, LEU58D, LEU74B, LEU74D, MET168B, MET168D, MET76B, MET76D, PHE188B, PHE188D, PHE47B, PHE47D, PRO79B, PRO79D, PRO95B, PRO95D, SER46B, SER46D, SER49B, SER49D, SER57B, SER57D, THR134B, THR134D, TRP159B, TRP159D, VAL185B, VAL185D, VAL55B, VAL55D
• B-E: ARG278B, GLU132E, LYS52B, THR133E
• B-F: ALA145F, ALA175F, ALA268B, ALA292B, ARG121B, ARG170F, ARG171F, ARG172F, ARG184F, ARG185F, ARG238B, ARG239B, ARG252B, ARG267B, ARG278B, ARG281B, ARG282B, ARG59B, ARG64B, ARG80B, ARG81B, ASN103B, ASN137F, ASN174F, ASN264B, ASN266B, ASN35B, ASN51B, ASN88B, ASP105B, ASP109B, ASP118B, ASP179F, ASP274B, ASP77B, GLN169F, GLN178F, GLN182B, GLN183F, GLN190F, GLN275B, GLN39B, GLN53B, GLN75B, GLN85B, GLU181B, GLU181F, GLU189F, GLU216B, GLU250B, GLU293B, GLU299B, GLU56B, GLU82B, GLU94B, GLU98B, GLY104B, GLY143F, GLY215B, GLY257B, GLY298B, GLY54B, GLY78B, HIS187F, ILE107B, ILE115B, ILE173F, ILE249B, ILE294B, ILE296B, ILE48B, ILE50B, ILE90B, LEU102B, LEU111B, LEU139F, LEU150F, LEU172B, LEU177F, LEU182F, LEU186F, LEU210B, LEU253B, LEU258B, LEU277B, LEU300B, LEU36B, LEU58B, LEU73B, LEU74B, LEU97B, LYS144F, LYS217B, LYS52B, MET141F, MET142F, MET176F, MET247B, MET76B, PHE100B, PHE136F, PHE183B, PHE231B, PHE259B, PHE261B, PHE47B, PHE93B, PRO112B, PRO134F, PRO140F, PRO147F, PRO213B, PRO248B, PRO69B, PRO79B, PRO95B, PRO99B, SER110B, SER113B, SER146F, SER149F, SER188F, SER211B, SER235B, SER236B, SER237B, SER251B, SER255B, SER260B, SER262B, SER271B, SER272B, SER285B, SER287B, SER38B, SER49B, SER57B, SER91B, THR101B, THR117B, THR133F, THR138F, THR269B, THR273B, THR279B, THR283B, THR286B, THR295B, TYR106B, TYR116B, TYR156B, TYR180F, TYR254B, TYR92B, VAL108B, VAL135F, VAL148F, VAL212B, VAL214B, VAL234B, VAL263B, VAL265B, VAL284B, VAL288B, VAL297B, VAL55B, VAL83B
• B-H: ALA137B, ARG135B, ARG169B, ARG184B, ASN137H, ASN51B, ASP171B, GLN182B, GLN53B, GLU178B, GLU181B, GLY280B, GLY54B, ILE136B, ILE48B, ILE50B, LEU139H, LEU172B, LEU173B, LEU180B, LYS52B, PHE136H, PHE183B, PRO134H, PRO140H, SER49B, THR134B, THR138H, THR179B, TRP159B, VAL135H, VAL55B
• C-E: ALA137C, ARG135C, ARG169C, ARG184C, ASN137E, ASN51C, ASP171C, GLN182C, GLN53C, GLU132E, GLU178C, GLU181C, GLY280C, GLY54C, ILE136C, ILE186C, ILE48C, ILE50C, LEU139E, LEU172C, LEU173C, LEU180C, LYS52C, PHE136E, PHE183C, PRO134E, PRO140E, SER49C, THR133E, THR134C, THR138E, THR179C, TRP159C, VAL135E, VAL55C
• C-G: ALA145G, ALA175G, ALA268C, ARG121C, ARG170G, ARG171G, ARG172G, ARG184G, ARG185G, ARG238C, ARG239C, ARG252C, ARG267C, ARG278C, ARG281C, ARG282C, ARG59C, ARG80C, ARG81C, ASN103C, ASN137G, ASN174G, ASN264C, ASN266C, ASN35C, ASN51C, ASP105C, ASP109C, ASP118C, ASP179G, ASP256C, ASP77C, GLN169G, GLN178G, GLN182C, GLN183G, GLN190G, GLN275C, GLN39C, GLN53C, GLN75C, GLU181C, GLU181G, GLU189G, GLU233C, GLU250C, GLU293C, GLU299C, GLU56C, GLU82C, GLU94C, GLU98C, GLY104C, GLY143G, GLY257C, GLY298C, GLY54C, GLY78C, GLY96C, HIS187G, ILE107C, ILE115C, ILE173G, ILE249C, ILE294C, ILE296C, ILE48C, ILE50C, ILE90C, LEU102C, LEU111C, LEU139G, LEU172C, LEU177G, LEU182G, LEU186G, LEU210C, LEU253C, LEU258C, LEU277C, LEU300C, LEU58C, LEU73C, LEU74C, LEU97C, LYS144G, LYS52C, MET141G, MET142G, MET176G, MET76C, PHE100C, PHE136G, PHE183C, PHE231C, PHE259C, PHE261C, PHE47C, PHE93C, PRO112C, PRO140G, PRO147G, PRO270C, PRO79C, PRO95C, PRO99C, SER110C, SER113C, SER146G, SER188G, SER232C, SER235C, SER236C, SER237C, SER251C, SER255C, SER260C, SER262C, SER271C, SER272C, SER49C, SER57C, SER91C, THR101C, THR117C, THR138G, THR269C, THR273C, THR279C, THR283C, THR286C, THR295C, TYR106C, TYR116C, TYR180G, TYR254C, TYR92C, VAL108C, VAL135G, VAL148G, VAL234C, VAL263C, VAL265C, VAL284C, VAL288C, VAL297C, VAL55C, VAL83C
• D-F: ALA137D, ARG135D, ARG169D, ARG184D, ASN137F, ASN51D, ASP171D, GLN182D, GLN53D, GLU132F, GLU178D, GLU181D, GLY177D, GLY280D, GLY54D, ILE136D, ILE186D, ILE48D, ILE50D, LEU139F, LEU172D, LEU173D, LEU180D, LYS52D, PHE136F, PHE183D, PRO134F, PRO140F, SER49D, THR133F, THR134D, THR138F, THR179D, TRP159D, VAL135F, VAL55D
• D-H: ALA145H, ALA175H, ARG184H, ARG185H, ARG252D, ARG278D, ARG281D, ARG282D, ARG59D, ARG80D, ARG81D, ASN103D, ASN137H, ASN174H, ASN264D, ASN266D, ASN51D, ASP105D, ASP109D, ASP179H, ASP77D, GLN178H, GLN182D, GLN183H, GLN275D, GLN53D, GLN75D, GLU181D, GLU181H, GLU250D, GLU293D, GLU299D, GLU56D, GLU82D, GLU94D, GLU98D, GLY104D, GLY143H, GLY298D, GLY54D, GLY78D, HIS187H, ILE107D, ILE173H, ILE294D, ILE296D, ILE48D, ILE50D, ILE90D, LEU102D, LEU111D, LEU139H, LEU172D, LEU177H, LEU180D, LEU182H, LEU186H, LEU209D, LEU210D, LEU253D, LEU258D, LEU277D, LEU300D, LEU58D, LEU73D, LEU74D, LEU97D, LYS144H, LYS52D, MET141H, MET142H, MET176H, MET76D, PHE100D, PHE136H, PHE183D, PHE259D, PHE261D, PHE47D, PHE93D, PRO112D, PRO134H, PRO140H, PRO147H, PRO79D, PRO95D, PRO99D, SER110D, SER113D, SER146H, SER188H, SER235D, SER236D, SER237D, SER251D, SER255D, SER260D, SER262D, SER271D, SER49D, SER57D, SER91D, THR101D, THR138H, THR279D, THR283D, THR286D, THR295D, TYR106D, TYR116D, TYR156D, TYR180H, TYR254D, TYR92D, VAL108D, VAL135H, VAL148H, VAL234D, VAL263D, VAL265D, VAL284D, VAL297D, VAL55D, VAL83D
• E-G: ASN137E, ASN137G, PHE136E, PHE136G, PRO134E, THR133E, VAL135E, VAL135G
• F-H: ASN137F, ASN137H, PHE136F, PHE136H, PRO134F, PRO134H, THR133F, VAL135F, VAL135H