3LS8

crystal structure of human pik3c3 in complex with 3-[4-(4- morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 100
  • Norm. En. per Res.: -2.4719
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-37.996	-76.8392	-132.354	-247.1892	100	3	2	5331	5	62	31

Interface residues

• A-B: ALA615A, ALA615B, ALA691A, ALA691B, ARG509A, ARG509B, ARG561B, ARG566A, ARG566B, ARG705A, ARG768A, ARG768B, ASN565A, ASN565B, ASN570B, ASN702A, ASN702B, ASP639A, ASP639B, ASP695A, ASP695B, ASP743A, ASP743B, ASP747A, ASP747B, ASP769A, ASP769B, ASP830A, ASP830B, GLN560A, GLN560B, GLN701A, GLN701B, GLU562A, GLU562B, GLU692A, GLU692B, GLU697A, GLU697B, GLU782A, GLU785A, GLU785B, GLY564A, GLY564B, GLY698A, GLY698B, GLY763A, GLY763B, HIS745A, HIS745B, ILE700A, ILE700B, LEU611A, LEU611B, LEU616A, LEU616B, LEU694A, LEU694B, LEU746A, LEU746B, LEU773A, LEU773B, LEU833A, LEU833B, LYS567A, LYS567B, LYS568A, LYS568B, LYS569A, LYS569B, LYS613A, LYS613B, LYS706A, LYS706B, LYS771A, LYS771B, LYS781A, LYS781B, MET617A, MET617B, PHE612A, PHE612B, PRO770A, PRO770B, PRO772A, PRO772B, PRO829A, PRO829B, SER563A, SER563B, SER614A, SER614B, SER699A, SER699B, THR696A, THR696B, TYR764A, TYR764B, VAL693A, VAL693B