3LO5

crystal structure of the dominant negative s17n mutant of ras

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 94
  • Norm. En. per Res.: -2.2008
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-20.7117	39.9256	-226.085	-206.8712	94	5	0	8964	1	48	44
A-E	-11.0113	6.7802	-73.1595	-77.3907	48	2	4	3116	0	25	21

Interface residues

• A-C: ALA130A, ALA130C, ALA134A, ALA134C, ALA155A, ALA155C, ARG123A, ARG123C, ARG128A, ARG128C, ARG135A, ARG135C, ARG161A, ARG161C, ARG164A, ARG164C, ASP132A, ASP132C, ASP154A, ASP154C, ASP47A, ASP47C, CYS118A, CYS118C, GLN131A, GLN131C, GLN150A, GLN150C, GLN165A, GLN165C, GLU126A, GLU126C, GLU143A, GLU143C, GLU153A, GLU153C, GLU162A, GLU162C, GLU49A, GLU49C, GLY115A, GLY115C, GLY138A, GLY138C, GLY151A, GLY151C, GLY48A, GLY48C, HIS166A, HIS166C, ILE139A, ILE139C, ILE142A, ILE142C, ILE163A, ILE163C, ILE46A, ILE46C, ILE84A, ILE84C, LEU113A, LEU113C, MET111A, MET111C, MET1A, PRO140A, PRO140C, SER127A, SER127C, SER136A, SER136C, THR144A, THR144C, THR158A, THR158C, THR2A, THR2C, THR50A, THR50C, TYR137A, TYR137C, TYR141A, TYR141C, TYR157A, TYR157C, TYR4A, TYR4C, VAL112A, VAL112C, VAL125A, VAL160A, VAL160C, VAL45A, VAL45C
• A-E: ALA121E, ALA122E, ALA130A, ALA134A, ALA83E, ARG102A, ARG123E, ARG135A, ASN85E, ASN86A, ASN86E, ASP119E, ASP132A, ASP30E, ASP92A, GLN129A, GLN129E, GLN131A, GLN95A, GLU126A, GLU126E, GLU31E, GLU91A, GLU91E, GLU98A, HIS94A, ILE84E, ILE93A, LEU113A, LEU120E, LEU133A, LYS101A, LYS117E, LYS147E, LYS88A, LYS88E, PHE90A, PHE90E, SER136A, SER89A, SER89E, THR124A, THR124E, THR87A, THR87E, TYR137A, VAL125A, VAL125E