3LNX

second pdz domain from human ptp1e

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 71
  • Norm. En. per Res.: -3.7548
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-49.5581	-32.7294	-165.362	-247.6495	75	7	5	6337	6	19	22
A-C	0.0	9.3754	-37.5121	-28.1367	21	1	0	1417	0	12	14
A-E	0.0	7.5333	-64.2083	-56.675	39	1	4	2882	0	11	10
A-F	0.0	6.8764	-58.2818	-51.4054	39	2	4	2739	0	10	9
B-C	0.0	7.1984	-62.1469	-54.9485	39	2	3	2873	0	11	9
B-D	0.0	7.4071	-64.3298	-56.9227	39	1	3	2955	0	11	9
B-F	0.0	9.2302	-32.8302	-23.5999	22	0	0	1291	0	11	14
C-D	0.0	7.5215	-66.3103	-58.7888	40	1	3	2949	0	11	10
C-E	-56.7962	-48.897	-160.9	-266.5932	71	7	6	6073	6	18	22
D-E	-11.2746	8.8423	-46.4244	-48.8567	21	1	0	1663	0	11	14
D-F	-48.9049	-26.188	-151.666	-226.7588	71	9	5	6064	3	18	22
E-F	0.0	7.267	-61.2026	-53.9356	39	3	3	2826	0	11	9

Interface residues

• A-B: ALA60A, ALA60B, ALA69A, ALA69B, ARG31A, ARG31B, ARG57A, ARG57B, ASN27A, ASN62A, ASN62B, ASP56B, ASP5A, ASP5B, GLN93A, GLN93B, GLU67A, GLU67B, GLU8A, GLU8B, GLU90A, GLU90B, GLY25A, GLY25B, GLY33A, GLY33B, GLY34A, GLY34B, GLY4A, GLY4B, GLY55A, GLY55B, GLY63A, GLY63B, GLY68A, GLY68B, GLY92A, GLY92B, HIS32A, HIS32B, HIS86A, HIS86B, ILE6A, ILE6B, LEU59A, LEU59B, LEU66A, LEU66B, LEU88A, LEU88B, LEU89A, LEU89B, LYS2A, LYS2B, LYS91A, LYS91B, PHE7A, PHE7B, PRO1A, PRO1B, PRO3A, PRO3B, SER29A, SER65A, SER65B, THR28A, TYR36A, TYR36B, VAL26A, VAL26B, VAL30A, VAL61A, VAL61B, VAL64A, VAL64B
• A-C: ARG51C, ASP5A, ASP5C, GLU8A, GLU8C, GLY50C, HIS53A, HIS53C, ILE6A, ILE6C, LYS2A, LYS2C, LYS91A, LYS91C, PHE7A, PHE7C, PRO1A, PRO1C, PRO3A, PRO3C, SER94C
• A-E: ALA12A, ALA12E, ALA45A, ALA46A, ARG51A, ARG79E, ASN14A, ASN62E, ASN80E, ASP15A, ASP49A, GLN83A, GLN83E, GLU10A, GLU10E, GLU47A, GLU8A, GLY44A, GLY50A, GLY63E, GLY82E, HIS86A, HIS86E, LEU11A, LEU11E, LEU87E, LYS13A, LYS13E, PHE7A, PRO1A, SER48A, THR81E, VAL61E, VAL64E, VAL84A, VAL84E, VAL85A, VAL85E, VAL9A
• A-F: ALA12A, ALA12F, ALA45F, ALA46F, ARG51F, ARG79A, ASN14F, ASN16A, ASN62A, ASN80A, ASP49F, GLN83A, GLN83F, GLU10A, GLU10F, GLU47F, GLU8F, GLY44F, GLY50F, GLY63A, GLY82A, HIS86A, HIS86F, LEU11A, LEU11F, LEU87A, LYS13A, LYS13F, PHE7F, PRO1F, SER48F, THR81A, VAL61A, VAL64A, VAL84A, VAL84F, VAL85A, VAL85F, VAL9F
• B-C: ALA12B, ALA12C, ALA45C, ALA46C, ARG51C, ARG79B, ASN14C, ASN16B, ASN62B, ASN80B, ASP49C, GLN83B, GLN83C, GLU10B, GLU10C, GLU47C, GLU8C, GLY44C, GLY50C, GLY63B, GLY82B, HIS86B, HIS86C, LEU11B, LEU11C, LEU87B, LYS13B, LYS13C, PHE7C, PRO1C, SER48C, THR81B, VAL61B, VAL64B, VAL84B, VAL84C, VAL85B, VAL85C, VAL9C
• B-D: ALA12B, ALA12D, ALA45B, ALA46B, ARG51B, ARG79D, ASN14B, ASN62D, ASN80D, ASP15B, ASP49B, GLN83B, GLN83D, GLU10B, GLU10D, GLU47B, GLU8B, GLY44B, GLY50B, GLY63D, GLY82D, HIS86B, HIS86D, LEU11B, LEU11D, LEU87D, LYS13B, LYS13D, PHE7B, PRO1B, SER48B, THR81D, VAL61D, VAL64D, VAL84B, VAL84D, VAL85B, VAL85D, VAL9B
• B-F: ARG51B, ARG51F, ASP5B, ASP5F, GLU8B, GLU8F, GLY50F, HIS53B, HIS53F, ILE6B, ILE6F, LYS2B, LYS2F, LYS91B, LYS91F, PHE7B, PHE7F, PRO1B, PRO1F, PRO3B, PRO3F, SER94B
• C-D: ALA12C, ALA12D, ALA45D, ALA46D, ARG51D, ARG79C, ASN14D, ASN62C, ASN80C, ASP15D, ASP49D, GLN83C, GLN83D, GLU10C, GLU10D, GLU47D, GLU8D, GLY44D, GLY50D, GLY63C, GLY82C, HIS86C, HIS86D, LEU11C, LEU11D, LEU87C, LYS13C, LYS13D, PHE7D, PRO1D, SER48D, THR81C, VAL61C, VAL64C, VAL84C, VAL84D, VAL85C, VAL85D, VAL9C, VAL9D
• C-E: ALA60C, ALA60E, ALA69C, ALA69E, ARG31C, ARG31E, ARG57C, ARG57E, ASN27E, ASN62C, ASN62E, ASP5C, ASP5E, GLN93E, GLU67C, GLU67E, GLU8C, GLU8E, GLU90C, GLU90E, GLY25E, GLY33C, GLY33E, GLY34C, GLY34E, GLY4C, GLY4E, GLY55E, GLY63C, GLY63E, GLY68C, GLY68E, GLY92C, GLY92E, HIS32C, HIS32E, HIS86C, HIS86E, ILE6C, ILE6E, LEU59C, LEU59E, LEU66C, LEU66E, LEU88C, LEU88E, LEU89C, LEU89E, LYS2C, LYS2E, LYS91C, LYS91E, PHE7C, PHE7E, PRO1C, PRO1E, PRO3C, PRO3E, SER29E, SER65C, SER65E, THR28E, TYR36C, TYR36E, VAL26C, VAL26E, VAL30E, VAL61C, VAL61E, VAL64C, VAL64E
• D-E: ASP5D, ASP5E, GLN93E, GLU8D, GLU8E, GLY92E, HIS53D, HIS53E, ILE6D, ILE6E, LYS2D, LYS2E, LYS91D, LYS91E, PHE7D, PHE7E, PRO1D, PRO1E, PRO3D, PRO3E, SER94E
• D-F: ALA60D, ALA60F, ALA69D, ALA69F, ARG31D, ARG31F, ARG57D, ARG57F, ASN27F, ASN62D, ASN62F, ASP5D, ASP5F, GLN93D, GLU67D, GLU67F, GLU8D, GLU8F, GLU90D, GLU90F, GLY25F, GLY33D, GLY33F, GLY34D, GLY34F, GLY4D, GLY4F, GLY55D, GLY55F, GLY63D, GLY63F, GLY68D, GLY68F, GLY92D, GLY92F, HIS32D, HIS32F, HIS86D, HIS86F, ILE35F, ILE6D, ILE6F, LEU59D, LEU59F, LEU66D, LEU66F, LEU88D, LEU88F, LEU89D, LEU89F, LYS2D, LYS2F, LYS91D, LYS91F, PHE7D, PHE7F, PRO1D, PRO1F, PRO3D, PRO3F, SER65D, SER65F, SER94D, TYR36D, TYR36F, VAL26D, VAL26F, VAL61D, VAL61F, VAL64D, VAL64F
• E-F: ALA12E, ALA12F, ALA45E, ALA46E, ARG51E, ARG79F, ASN14E, ASN62F, ASN80F, ASP15E, ASP49E, GLN83E, GLN83F, GLU10E, GLU10F, GLU47E, GLU8E, GLY44E, GLY50E, GLY63F, GLY82F, HIS86E, HIS86F, LEU11E, LEU11F, LEU87F, LYS13E, LYS13F, PHE7E, PRO1E, SER48E, THR81F, VAL61F, VAL64F, VAL84E, VAL84F, VAL85E, VAL85F, VAL9E