3LNJ

crystal structure of human mdm2 in complex with d-peptide inhibitor (dpmi-alpha)

• Total interactions analyzed: 15
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 61
  • Norm. En. per Res.: -2.2678
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	0.0	18.8634	-157.201	-138.3376	61	8	5	6048	0	10	18
A-E	0.0	0.0	-0.0779	-0.0779	5	0	0	29	0	0	0
C-E	0.0	0.0	-66.9966	-66.9966	35	0	0	2586	0	5	4

Interface residues

• A-C: ARG105A, ARG105C, ARG29A, ARG29C, ARG97A, ARG97C, ASN106A, ASN106C, GLU52A, GLU52C, GLU95A, GLU95C, GLY87A, GLY87C, HIS96A, HIS96C, ILE103A, ILE103C, ILE99A, ILE99C, LEU107A, LEU107C, LEU27A, LEU27C, LEU54A, LEU54C, LEU85C, LYS31A, LYS51A, LYS51C, LYS98A, LYS98C, MET102A, MET102C, MET50A, MET50C, PHE55A, PHE55C, PHE86A, PHE86C, PRO30A, THR101A, THR101C, THR26A, THR26C, THR49A, THR49C, TYR100A, TYR100C, TYR104A, TYR104C, TYR48A, TYR48C, VAL108A, VAL108C, VAL28A, VAL28C, VAL53A, VAL53C, VAL88A, VAL88C
• A-E: GLN44E, GLY42E, THR26A, THR49A, VAL41E
• C-E: ALA43E, ARG105C, ASN79C, ASP80C, ASP84C, CYS77C, GLN44E, GLN59E, GLU52E, GLY42E, GLY58E, GLY83C, GLY87C, LEU33C, LEU54E, LEU81C, LEU82C, LEU85C, LYS51E, LYS98C, MET50E, MET62E, PHE55E, PHE86C, PRO89C, SER78C, SER90C, THR49E, THR63E, TYR48E, TYR56E, TYR76C, VAL41E, VAL53E, VAL88C