3LDZ

crystal structure of human stam1 vhs domain in complex with ubiquitin

• Total interactions analyzed: 21
• Total true interactions: 9
• Strongest Interaction:
  • Chains: F-C
  • Int. Res.: 48
  • Norm. En. per Res.: -4.2377
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
F-C	-36.0742	-70.9423	-96.3947	-203.4112	48	5	1	4161	6	18	6
F-E	0.0	-5.5234	-30.4985	-36.0219	25	0	0	1261	2	8	9
A-D	-9.3675	-25.2104	-38.9389	-73.5168	33	3	0	2183	1	24	26
A-B	0.0	-9.3184	-0.5276	-9.846	10	0	0	114	0	9	15
A-C	-6.9826	12.1258	-119.064	-113.9207	89	4	2	6475	7	29	44
D-B	-4.4099	24.6516	-94.7757	-74.534	81	10	2	5690	3	30	39
D-G	-33.603	-37.6432	-91.0797	-162.3259	48	6	1	3913	3	17	5
B-C	-11.3099	-5.9894	-53.7673	-71.0666	38	3	0	2483	1	26	21
B-E	-22.823	-9.6038	-96.2568	-128.6837	47	4	1	3907	3	17	5

Interface residues

• F-C: ALA23C, ALA46F, ALA71C, ARG42F, ARG72F, ASN75C, ASP25C, ASP31C, ASP34C, CYS33C, CYS72C, CYS76C, GLN41F, GLN49F, GLU114C, GLU118C, GLU24C, GLU51F, GLY10F, GLY27C, GLY47F, GLY70C, GLY77C, HIS68F, HIS81C, ILE29C, ILE32C, ILE44F, LEU111C, LEU28C, LEU30C, LEU43F, LEU50F, LEU68C, LEU69F, LEU71F, LEU8F, LYS107C, LYS35C, LYS48F, LYS6F, PHE45F, SER74C, THR67C, THR7F, TRP26C, VAL70F, VAL73C
• F-E: GLN2E, GLN2F, GLU16E, GLU34E, GLU64E, GLU64F, GLY10F, ILE13E, ILE13F, LEU15E, LYS11F, LYS33E, LYS63E, LYS63F, LYS6F, PHE4E, PHE4F, SER65F, THR12E, THR12F, THR14E, THR14F, THR66E, THR66F, VAL5F
• A-D: ALA23A, ALA62D, ASN21A, ASP58A, ASP58D, CYS105D, GLN64A, GLU106A, GLU106D, GLU19A, GLU19D, GLU24A, HIS101A, HIS101D, HIS56D, HIS60A, HIS60D, LYS103A, LYS103D, LYS57D, MET20A, MET20D, MET63A, PRO102A, PRO102D, PRO59A, PRO59D, SER18A, THR22A, THR22D, VAL104D, VAL61A, VAL61D
• A-B: ASP58A, ASP58B, GLU19A, GLU19B, HIS60A, HIS60B, LYS57A, LYS57B, PRO59A, PRO59B
• A-C: ALA130A, ALA130C, ALA5A, ALA5C, ALA90A, ALA90C, ARG48A, ARG48C, ARG52A, ARG52C, ARG53A, ARG53C, ARG87A, ARG87C, ASN134A, ASN134C, ASN55A, ASN55C, ASN7A, ASN7C, ASN95A, ASN95C, ASN98A, ASN98C, ASP10A, ASP10C, ASP58A, ASP58C, ASP88A, ASP88C, CYS85A, GLN138A, GLN138C, GLU137A, GLU14A, GLU14C, GLU19A, GLU19C, GLU92A, GLU92C, GLY100A, GLY100C, HIS101A, HIS101C, HIS56A, HIS56C, ILE128A, ILE132A, ILE50C, LEU127A, LEU127C, LEU135A, LEU135C, LYS133A, LYS57A, LYS57C, LYS99A, LYS99C, MET131A, MET131C, MET51A, MET51C, PHE4A, PHE4C, PHE89A, PHE89C, PRO102C, PRO59A, PRO59C, SER126A, SER129A, SER18A, SER49C, SER86A, SER91A, SER91C, SER94A, SER94C, THR17C, THR6A, THR6C, VAL13C, VAL54C, VAL61A, VAL61C, VAL93A, VAL93C, VAL96A, VAL96C
• D-B: ALA130B, ALA130D, ALA5B, ALA5D, ALA90B, ALA90D, ARG48B, ARG48D, ARG52B, ARG52D, ARG53B, ARG53D, ARG87B, ARG87D, ASN134B, ASN134D, ASN55B, ASN55D, ASN7B, ASN7D, ASN95B, ASN95D, ASN98B, ASN98D, ASP10D, ASP58B, ASP58D, ASP88B, ASP88D, CYS85B, GLN138B, GLN138D, GLU137B, GLU14B, GLU14D, GLU19B, GLU19D, GLU92B, GLU92D, GLY100B, GLY100D, HIS101B, HIS101D, HIS56B, HIS56D, ILE128B, ILE132B, LEU127B, LEU127D, LEU135B, LYS133B, LYS57B, LYS57D, LYS99B, LYS99D, MET131B, MET131D, MET51B, PHE4B, PHE4D, PHE89B, PRO102D, PRO59B, PRO59D, SER126B, SER129B, SER18B, SER18D, SER86B, SER91B, SER91D, SER94B, SER94D, THR17D, THR6B, THR6D, VAL61B, VAL61D, VAL93B, VAL96B, VAL96D
• D-G: ALA23D, ALA46G, ALA71D, ARG42G, ARG72G, ASN75D, ASP25D, ASP31D, ASP34D, CYS33D, CYS72D, CYS76D, GLN49G, GLU114D, GLU118D, GLU24D, GLU51G, GLY10G, GLY27D, GLY47G, GLY70D, GLY77D, HIS68G, HIS81D, ILE29D, ILE32D, ILE44G, LEU111D, LEU28D, LEU30D, LEU43G, LEU50G, LEU68D, LEU69G, LEU71G, LEU73G, LEU8G, LYS107D, LYS48G, LYS6G, PHE45G, SER74D, THR67D, THR7G, TRP26D, TYR59G, VAL70G, VAL73D
• B-C: ALA23B, ASN21B, ASN21C, ASP58B, ASP58C, CYS105C, GLN64B, GLN64C, GLU106B, GLU106C, GLU19B, GLU19C, GLU24B, GLY100C, HIS101B, HIS101C, HIS56C, HIS60B, HIS60C, LYS103B, LYS103C, LYS107C, LYS57C, MET20B, MET20C, MET63B, MET63C, PRO102B, PRO102C, PRO59B, PRO59C, SER18B, SER18C, THR22B, THR22C, VAL104C, VAL61B, VAL61C
• B-E: ALA23B, ALA46E, ALA71B, ARG42E, ARG72E, ASN75B, ASP25B, ASP31B, ASP34B, CYS33B, CYS72B, CYS76B, GLN49E, GLU114B, GLU118B, GLU24B, GLU51E, GLY10E, GLY27B, GLY47E, GLY70B, GLY77B, HIS68E, HIS81B, ILE29B, ILE32B, ILE44E, LEU111B, LEU28B, LEU30B, LEU43E, LEU50E, LEU68B, LEU69E, LEU71E, LEU8E, LYS107B, LYS48E, LYS6E, PHE45E, SER74B, THR67B, THR7E, TRP26B, TYR59E, VAL70E, VAL73B