3LD0

crystal structure of b.licheniformis anti-trap protein, an antagonist of trap-rna interactions

• Total interactions analyzed: 1128
• Total true interactions: 257
• Strongest Interaction:
  • Chains: J-L
  • Int. Res.: 55
  • Norm. En. per Res.: -4.299
• Hub Node: C(23)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-37.4545	-27.0355	-152.929	-217.419	54	5	6	6912	3	18	14
A-C	-37.8646	-16.9692	-151.093	-205.9268	58	7	5	7130	3	19	16
A-D	-4.2553	28.8237	-18.8864	5.682	17	3	0	791	0	3	7
A-E	0.0	9.0513	-0.1035	8.9479	2	0	0	9	0	3	2
A-F	0.0	0.0	-0.0294	-0.0294	2	0	0	3	0	1	1
A-G	0.0	-3.5518	-4.2046	-7.7564	7	0	0	214	0	4	7
A-I	0.0	11.956	-26.1407	-14.1847	14	5	0	981	0	9	18
A-J	0.0	2.6964	-123.088	-120.3916	58	5	3	5637	0	16	21
A-K	-2.1201	3.1996	-19.0247	-17.9452	13	0	0	806	0	8	17
A-L	-3.9261	15.7218	-17.8913	-6.0956	17	1	0	718	0	4	7
A-e	0.0	0.0	-12.4058	-12.4058	6	0	1	430	0	0	0
A-f	0.0	0.0	-0.1718	-0.1718	9	0	0	49	0	0	4
B-C	-37.4343	-25.5278	-152.451	-215.4131	56	5	6	6903	3	16	17
B-D	0.0	2.4172	-133.173	-130.7558	61	2	4	5853	0	16	21
B-E	0.0	8.0564	-6.212	1.8444	16	2	0	799	0	9	17
B-F	-5.4537	10.1159	-15.69	-11.0278	14	1	0	678	0	3	6
B-I	-7.7482	11.8236	-18.9189	-14.8435	17	1	0	737	0	4	6
B-J	0.0	-1.1662	-25.3258	-26.492	16	2	0	839	1	9	18
B-K	0.0	17.2605	-17.0946	0.1659	8	1	0	539	0	8	6
B-L	0.0	0.0	-0.162	-0.162	2	0	0	19	0	3	2
B-R	-5.1093	0.0	-15.73	-20.8393	21	1	0	802	0	2	2
B-S	0.0	0.0	-22.4552	-22.4552	21	0	0	1186	0	2	2
B-e	0.0	0.0	-4.0957	-4.0957	8	0	1	264	0	0	4
B-f	0.0	0.0	-3.627	-3.627	6	0	1	176	0	0	0
B-g	0.0	0.0	-9.3707	-9.3707	7	0	1	416	0	0	0
C-D	0.0	12.327	-23.7634	-11.4364	14	6	0	873	0	8	18
C-E	0.0	19.8249	-11.9021	7.9228	8	0	0	352	0	7	8
C-F	0.0	6.7505	-0.157	6.5934	2	0	0	29	0	3	2
C-G	0.0	1.9506	-21.2797	-19.3291	14	2	0	714	0	4	17
C-H	-6.5407	9.3938	-18.6056	-15.7524	17	1	0	735	0	3	6
C-I	0.0	0.6561	-117.253	-116.597	59	1	3	5613	0	16	21
C-J	-8.9698	11.1923	-18.4512	-16.2288	17	3	0	705	0	4	8
C-K	0.0	0.0	-0.1645	-0.1645	2	0	0	21	0	3	2
C-L	0.0	0.0	-0.0009	-0.0009	2	0	0	2	0	2	1
C-Z	0.0	0.0	-0.1777	-0.1777	7	0	0	50	0	3	6
C-4	0.0	1.1428	-0.6366	0.5062	6	0	0	104	0	2	4
C-e	0.0	0.0	-1.1383	-1.1383	3	0	1	111	0	0	0
C-f	0.0	0.0	-17.8597	-17.8597	10	1	1	746	0	0	0
C-g	0.0	0.0	-0.0157	-0.0157	4	0	0	12	0	0	4
D-E	-32.1527	0.5436	-158.181	-189.7901	56	7	6	7173	3	20	16
D-F	-37.0347	6.3815	-170.407	-201.0602	57	7	7	7237	3	18	16
D-G	0.0	4.5529	-15.3057	-10.7528	14	1	0	727	0	4	17
D-H	0.0	0.0	-0.8577	-0.8577	7	0	0	128	0	3	6
D-I	0.0	5.8968	-0.6451	5.2517	3	0	0	31	0	3	2
D-J	0.0	7.7364	-0.3273	7.4092	3	0	0	29	0	3	2
D-K	0.0	2.3805	-0.0065	2.374	2	0	0	3	0	2	1
D-L	-4.9168	8.9708	-18.7044	-14.6504	16	2	0	780	0	5	8
D-S	0.0	0.0	-13.3979	-13.3979	18	2	0	706	0	1	1
E-F	-41.3315	-21.4992	-149.517	-212.3477	56	6	6	6819	3	16	15
E-G	-6.1013	8.4426	-16.8676	-14.5262	17	2	0	669	0	2	6
E-I	0.0	1.0603	-0.0021	1.0582	2	0	0	1	0	2	1
E-J	0.0	15.5408	-25.0851	-9.5443	15	0	0	792	0	8	18
E-K	-6.8246	14.1272	-15.4119	-8.1093	17	1	0	674	0	5	7
E-L	0.0	2.2588	-122.638	-120.3792	59	1	3	5574	0	16	20
F-G	0.0	0.7519	-131.11	-130.3581	63	2	3	5946	0	15	20
F-H	0.0	1.9759	-23.0418	-21.0659	14	2	0	785	0	4	17
F-I	-6.258	16.3803	-18.8713	-8.749	18	2	0	723	0	5	8
F-J	0.0	5.5848	-10.3135	-4.7287	8	0	0	257	0	6	7
F-L	0.0	23.1213	-16.5493	6.572	15	0	0	778	0	8	18
G-H	-43.7871	-26.5977	-160.625	-231.0098	54	5	7	6942	3	10	17
G-I	-39.4829	-29.1077	-151.725	-220.3155	55	4	7	6782	3	13	15
G-K	-7.7212	0.0	-17.1958	-24.917	14	3	0	713	0	2	6
H-I	-39.3321	-26.5642	-148.774	-214.6703	54	4	7	6681	3	16	15
H-J	-4.9142	9.3225	-17.3349	-12.9266	14	1	0	691	0	3	6
H-K	0.0	1.3605	-131.875	-130.5145	60	4	2	5862	0	14	20
H-L	0.0	0.9831	-14.1369	-13.1538	13	1	0	622	0	4	16
H-2	0.0	0.0	-16.6246	-16.6246	16	0	0	750	0	2	2
H-3	0.0	0.0	-12.8254	-12.8254	15	0	0	597	0	1	2
H-4	0.0	0.0	-0.3573	-0.3573	5	0	0	73	0	0	2
H-a	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	1	3
I-J	0.0	2.4938	-0.0663	2.4275	2	0	0	15	0	3	2
I-K	0.0	3.3863	-20.8381	-17.4518	15	7	0	919	1	8	18
I-L	0.0	24.7909	-9.7842	15.0067	8	0	0	402	0	7	7
J-K	-33.3702	-28.4215	-155.289	-217.0806	55	5	6	6939	3	19	17
J-L	-44.1496	-24.5836	-167.713	-236.4462	55	5	7	7089	3	19	17
K-L	-38.8681	-25.8686	-166.069	-230.8057	56	6	6	7000	3	16	16
M-N	-32.0268	-24.2799	-154.629	-210.9357	55	3	6	6863	2	13	16
M-O	-28.3849	-16.8835	-169.937	-215.2054	57	3	6	7161	2	18	16
M-P	-4.4232	9.9993	-16.2903	-10.7142	14	2	0	687	0	4	7
M-S	0.0	6.791	-0.8559	5.9351	8	0	0	145	0	6	7
M-T	0.0	1.0416	-0.0257	1.0159	2	0	0	5	0	3	2
M-U	0.0	12.1153	-18.9532	-6.8379	15	6	0	823	0	8	17
M-V	0.0	4.4204	-128.493	-124.0726	62	1	4	5872	0	17	21
M-W	0.0	5.6832	-30.3429	-24.6597	14	4	0	843	0	8	18
M-X	-8.7841	9.159	-17.3633	-16.9884	17	1	0	646	0	3	6
N-O	-34.6001	-27.7008	-142.972	-205.2729	54	9	7	6784	3	12	16
N-P	0.0	-0.2437	-119.472	-119.7157	59	1	3	5503	0	15	19
N-Q	0.0	7.497	-14.7863	-7.2893	14	2	0	612	0	4	17
N-R	-8.0192	10.0186	-15.2226	-13.2232	14	1	0	716	0	2	6
N-U	-5.9793	9.1498	-17.8088	-14.6382	15	1	0	725	0	3	7
N-V	0.0	4.8812	-6.344	-1.4628	11	0	0	496	0	4	17
N-W	0.0	-2.1217	-0.9529	-3.0746	7	0	0	142	0	4	6
O-P	0.0	-2.8033	-23.2662	-26.0695	16	2	0	1019	1	8	18
O-Q	0.0	0.0	-0.3454	-0.3454	8	0	0	96	0	4	7
O-R	0.0	4.0006	-0.0633	3.9373	2	0	0	20	0	3	2
O-S	0.0	12.8379	-35.3969	-22.559	16	4	0	995	0	8	18
O-T	-9.7747	10.3674	-17.7657	-17.173	16	3	0	720	0	4	7
O-U	0.0	1.5571	-124.962	-123.4049	60	3	4	5633	0	17	21
O-V	-6.7244	13.1144	-17.9607	-11.5707	17	2	0	735	0	4	7
O-W	0.0	8.0621	-0.923	7.1391	2	0	0	49	0	3	2
P-Q	-34.2144	-27.7847	-166.368	-228.367	56	5	7	7214	3	17	16
P-R	-38.1727	-26.9244	-166.439	-231.5361	55	5	7	7045	3	18	16
P-S	0.0	13.6102	-18.7695	-5.1593	14	0	0	794	0	7	17
P-T	0.0	0.0	-0.359	-0.359	8	0	0	84	0	4	7
P-V	0.0	4.6272	-0.9423	3.6849	3	0	0	29	0	3	2
P-W	0.0	0.0	-0.0693	-0.0693	2	0	0	5	0	1	1
P-X	-6.437	10.014	-14.88	-11.3029	15	1	0	689	0	4	8
Q-R	-34.6663	-30.9307	-157.999	-223.596	57	10	5	7152	3	18	16
Q-S	-5.7804	9.5003	-16.0929	-12.3729	17	2	0	686	0	4	7
Q-T	0.0	4.1701	-0.002	4.1681	2	0	0	2	0	3	2
Q-V	0.0	5.2735	-25.2222	-19.9487	15	4	0	1024	1	9	17
Q-W	-7.4499	14.9991	-16.3268	-8.7776	17	3	0	675	0	4	7
Q-X	0.0	34.2306	-133.063	-98.8324	62	1	3	5949	0	18	21
R-S	0.0	19.27	-125.406	-106.136	61	6	2	5929	0	17	21
R-T	0.0	15.4175	-35.011	-19.5936	14	5	0	1021	0	8	17
R-U	-4.7867	17.5932	-17.0775	-4.271	17	1	0	727	0	5	8
R-V	0.0	9.577	-5.4924	4.0845	8	0	0	265	0	7	7
R-W	0.0	6.0613	-0.1815	5.8798	2	0	0	28	0	3	2
R-X	0.0	6.5548	-23.2492	-16.6944	16	2	0	950	0	8	18
S-T	-30.768	-11.6479	-152.183	-194.5989	55	5	6	6863	2	17	16
S-U	-26.7708	-7.2011	-143.387	-177.3588	56	6	6	7054	3	15	17
S-V	0.0	29.0791	-2.8983	26.1808	2	0	0	35	0	2	1
S-W	-3.8828	35.4019	-19.8316	11.6875	16	2	0	743	0	3	6
S-X	0.0	0.0	-0.1026	-0.1026	2	0	0	9	0	1	2
S-m	0.0	5.5617	-10.3089	-4.7473	12	1	0	543	0	1	5
T-U	-38.8714	-19.6078	-163.93	-222.4093	56	8	6	7138	2	19	17
T-V	-8.8362	15.3883	-14.767	-8.2149	17	2	0	754	0	6	8
T-W	0.0	3.4522	-115.466	-112.0138	60	3	3	5459	0	16	20
T-X	0.0	12.5659	-21.3781	-8.8122	14	0	0	813	0	7	18
T-e	0.0	0.0	-1.9484	-1.9484	9	0	0	232	0	0	0
T-m	0.0	0.0	-0.0511	-0.0511	4	0	0	20	0	1	1
U-V	0.0	12.5465	-0.6117	11.9348	2	0	0	43	0	3	2
U-W	0.0	17.2146	-17.6394	-0.4248	13	0	0	813	0	8	18
U-X	-2.8068	4.6661	-7.3156	-5.4563	8	0	0	231	0	5	6
U-e	0.0	0.0	-0.7289	-0.7289	6	0	0	80	0	0	0
U-m	0.0	0.0	-0.0247	-0.0247	3	0	0	17	0	0	0
V-W	-35.3489	0.0347	-174.493	-209.8072	57	8	6	7174	3	18	16
V-X	-35.3312	-3.7199	-176.872	-215.923	55	7	6	7323	3	19	17
W-X	-35.5023	-19.8587	-160.063	-215.424	55	7	7	6976	2	18	16
W-m	0.0	0.0	-0.3016	-0.3016	5	0	0	28	0	1	2
Y-Z	-39.565	-17.7857	-144.986	-202.3368	54	6	6	6776	3	15	15
Y-1	-34.9715	-6.7232	-162.845	-204.5397	56	4	6	7018	2	20	17
Y-2	-5.0856	9.6214	-17.2925	-12.7567	15	3	0	753	0	3	7
Y-3	0.0	30.575	-3.4803	27.0947	3	0	0	58	0	3	2
Y-5	0.0	16.7102	-4.1213	12.5889	8	1	0	235	0	6	7
Y-6	0.0	0.0	-0.0828	-0.0828	2	0	0	8	0	3	2
Y-7	0.0	42.5943	-23.1899	19.4044	16	2	0	885	0	8	18
Y-8	0.0	11.1025	-117.896	-106.7935	59	2	4	5528	0	16	21
Y-9	0.0	9.5717	-23.6943	-14.1226	14	6	0	895	0	8	18
Y-a	-2.9223	20.069	-18.7347	-1.588	17	0	0	740	0	5	7
Z-1	-42.2482	-25.4962	-147.035	-214.7794	56	3	6	6708	3	12	14
Z-2	0.0	0.9464	-130.849	-129.9026	57	0	4	5925	0	12	20
Z-3	0.0	5.6272	-13.9902	-8.363	15	2	0	635	0	4	17
Z-4	-3.9752	9.3519	-18.3896	-13.0128	14	0	0	702	0	2	5
Z-7	-5.0053	9.705	-16.6814	-11.9818	14	1	0	689	0	3	6
Z-8	0.0	2.609	-16.2197	-13.6107	13	0	0	667	0	4	17
Z-9	0.0	-1.4953	-3.9232	-5.4186	7	0	0	208	0	4	7
1-2	0.0	2.2429	-11.5545	-9.3116	13	0	0	633	0	4	17
1-3	0.0	38.8609	-14.874	23.9869	8	0	0	364	0	6	8
1-5	0.0	23.6501	-20.7357	2.9144	15	5	0	921	0	8	17
1-6	-6.2948	8.9468	-17.539	-14.887	16	2	0	670	0	4	7
1-7	0.0	5.8109	-115.237	-109.4261	60	4	4	5697	0	16	21
1-8	-5.1249	19.1668	-16.296	-2.2541	18	4	0	763	0	4	8
1-9	0.0	3.8987	-0.2455	3.6532	2	0	0	26	0	3	2
1-a	0.0	7.73	-0.1687	7.5613	2	0	0	26	0	2	1
2-3	-26.294	-18.6513	-145.57	-190.5153	56	6	5	6770	2	15	16
2-4	-37.147	-24.9256	-156.614	-218.6866	53	6	7	6836	3	10	16
2-5	0.0	5.8161	-9.786	-3.9699	11	0	0	600	0	4	17
2-6	0.0	0.0	-0.2141	-0.2141	6	0	0	62	0	1	6
2-a	-7.4875	9.2554	-19.5669	-17.799	17	2	0	731	0	3	7
3-4	-36.624	-26.5969	-143.643	-206.864	55	6	5	6694	3	14	14
3-5	-6.0011	24.0593	-17.8308	0.2274	18	2	0	737	0	3	8
3-7	0.0	11.1477	-0.1587	10.989	2	0	0	8	0	2	1
3-8	0.0	27.2391	-4.2638	22.9753	15	12	0	874	0	8	18
3-9	-8.7617	18.2351	-18.9587	-9.4853	17	1	0	716	0	4	7
3-a	0.0	8.3915	-129.694	-121.3025	60	4	3	5778	0	16	21
4-5	0.0	1.8358	-138.246	-136.4102	63	1	3	6016	0	14	20
4-6	0.0	8.2752	-13.5239	-5.2487	15	0	0	574	0	4	16
4-7	-8.4	10.0379	-18.8279	-17.19	15	1	0	698	0	2	6
4-8	0.0	0.0	-0.3939	-0.3939	7	0	0	105	0	4	6
4-a	0.0	3.1039	-10.8338	-7.7299	13	0	0	614	0	4	17
5-6	-36.4539	-17.5663	-164.802	-218.8222	56	6	6	7123	3	18	16
5-7	-38.6941	-15.1005	-158.794	-212.5886	56	4	7	7064	2	19	16
5-8	0.0	4.5909	-0.0508	4.5401	2	0	0	10	0	2	1
5-9	-3.8923	10.9112	-17.4228	-10.4039	16	2	0	711	0	4	7
5-a	0.0	32.3867	-2.753	29.6336	2	1	0	98	0	3	2
6-7	-41.4693	-4.0446	-181.981	-227.4948	56	6	7	7323	3	18	16
6-8	0.0	12.1488	-17.4478	-5.299	17	0	0	697	0	4	7
6-9	0.0	6.2599	-117.649	-111.389	61	5	2	5603	0	17	21
6-a	0.0	15.4188	-26.5171	-11.0983	14	9	0	1043	0	8	18
7-8	0.0	7.7373	-1.1306	6.6067	3	0	0	43	0	3	2
7-9	-8.162	18.1184	-20.6571	-10.7007	14	3	0	904	0	8	18
7-a	0.0	15.1835	-9.2459	5.9376	8	3	0	326	0	7	7
8-9	-37.3778	-18.5243	-163.986	-219.8882	58	4	6	7162	3	19	17
8-a	-34.6703	-20.4675	-168.441	-223.5788	56	6	7	7104	3	18	17
9-a	-41.0474	-27.657	-159.522	-228.2265	56	6	6	6934	3	19	16
b-c	-30.8646	-21.2506	-155.461	-207.5763	56	5	6	6891	3	17	16
b-d	-29.8152	1.3179	-164.304	-192.8013	56	8	5	7006	3	19	16
b-e	-5.5585	27.167	-17.0773	4.5312	16	2	0	777	0	4	7
b-g	0.0	9.8785	-0.1812	9.6973	2	0	0	17	0	2	1
b-h	0.0	13.1436	-3.2254	9.9182	8	0	0	215	0	6	6
b-i	0.0	9.419	-0.4891	8.9299	2	0	0	34	0	3	2
b-j	0.0	9.0592	-26.9997	-17.9405	15	16	0	1165	1	8	18
b-k	0.0	6.5076	-110.518	-104.0105	58	2	3	5283	0	16	22
b-l	0.0	3.1672	-8.9909	-5.8237	11	0	0	508	0	4	17
b-m	0.0	23.7926	-17.2153	6.5774	16	0	0	690	0	4	7
c-d	-36.3923	-8.2993	-168.493	-213.1845	55	7	6	7196	3	19	16
c-e	0.0	15.976	-124.889	-108.913	63	3	3	5747	0	16	21
c-f	-5.1399	11.9959	-29.1846	-22.3286	15	3	0	977	0	8	18
c-g	-6.6187	17.3832	-13.4432	-2.6787	17	2	0	739	0	4	7
c-h	0.0	13.9848	-0.5269	13.4578	2	0	0	29	0	3	2
c-j	-5.389	9.5392	-17.6922	-13.542	15	1	0	735	0	3	7
c-k	0.0	15.945	-12.2825	3.6625	14	5	0	769	0	8	18
c-l	0.0	0.0	-0.3439	-0.3439	7	0	0	82	0	3	6
c-m	0.0	0.0	-0.0033	-0.0033	2	0	0	3	0	2	2
d-e	0.0	43.0117	-18.0333	24.9784	15	0	0	748	0	8	17
d-f	0.0	8.5158	-1.1715	7.3442	8	0	0	158	0	5	7
d-g	0.0	16.0206	-0.7787	15.2419	2	0	0	37	0	3	2
d-h	0.0	28.2972	-22.7864	5.5108	16	5	0	906	0	8	18
d-i	-6.8677	17.0285	-18.218	-8.0572	16	2	0	742	0	5	7
d-j	0.0	4.8781	-121.266	-116.3879	59	2	3	5597	0	17	21
d-k	-4.849	29.4936	-19.6393	5.0052	18	2	0	775	0	5	7
d-l	0.0	0.0	-0.0504	-0.0504	2	0	0	4	0	1	0
d-m	0.0	5.7347	-0.2161	5.5186	2	0	0	20	0	2	1
e-f	-32.9306	-3.7705	-167.458	-204.1591	56	6	6	7209	3	17	17
e-g	-49.7259	7.1205	-153.987	-196.5924	54	9	7	7096	3	19	16
e-h	0.0	30.9197	-32.2551	-1.3354	14	3	0	990	0	8	18
e-i	0.0	26.3234	-12.9758	13.3476	8	0	0	328	0	7	8
e-j	0.0	3.8142	-0.0912	3.723	2	0	0	9	0	3	3
e-k	0.0	11.809	-0.9855	10.8235	2	0	0	56	0	3	2
e-m	-8.4112	17.0859	-17.9145	-9.2397	16	1	0	701	0	6	8
f-g	-25.2099	5.1223	-174.203	-194.2906	53	10	7	7237	3	19	17
f-h	-7.0249	9.1083	-19.8255	-17.7421	18	3	0	741	0	3	8
f-i	0.0	0.0	-0.0321	-0.0321	2	0	0	6	0	3	2
f-k	0.0	11.5912	-35.6005	-24.0094	15	10	0	1157	0	9	17
f-l	-3.7172	10.0651	-15.7748	-9.4269	14	1	0	642	0	2	6
f-m	0.0	7.5007	-126.159	-118.6583	62	3	3	5815	0	17	20
g-h	0.0	7.298	-127.709	-120.411	61	2	4	5819	0	16	21
g-i	0.0	11.0484	-24.5486	-13.5002	14	3	0	957	0	8	18
g-j	-10.2625	8.7887	-18.8855	-20.3593	14	1	0	673	0	3	7
g-k	0.0	14.3313	-9.4734	4.8579	8	0	0	317	0	7	8
g-l	0.0	0.0	-0.0114	-0.0114	3	0	0	3	0	2	2
g-m	-2.362	16.8289	-17.7418	-3.2749	15	4	0	915	0	8	18
h-i	-38.3327	-9.2534	-163.639	-211.2251	56	7	6	7249	3	20	16
h-j	-35.4465	-22.5198	-161.261	-219.2273	56	7	6	7134	3	19	16
h-k	0.0	0.0	-0.0091	-0.0091	2	0	0	2	0	2	1
h-l	-2.5513	9.5016	-19.9872	-13.0369	15	1	0	792	0	2	6
h-m	0.0	2.4031	-0.1544	2.2487	2	0	0	24	0	3	2
i-j	-38.232	-22.35	-164.4	-224.9819	58	6	7	7066	2	17	16
i-k	-7.3292	11.7641	-15.4691	-11.0342	16	2	0	724	0	4	8
i-l	0.0	-0.7243	-126.661	-127.3853	58	2	3	5632	0	14	19
i-m	0.0	7.4916	-22.4127	-14.9211	14	0	0	788	0	8	18
j-l	0.0	6.5286	-8.8322	-2.3036	13	0	0	586	0	4	17
j-m	0.0	1.0233	-5.3878	-4.3645	8	0	0	215	0	5	7
k-l	-33.792	-28.2378	-157.824	-219.8538	55	6	6	6871	3	14	14
k-m	-39.9702	-18.1993	-162.441	-220.6104	57	7	6	7306	2	18	16
l-m	-37.9852	-26.9074	-155.396	-220.2886	55	9	6	6861	3	12	16

Interface residues

• A-B: ALA104B, ALA138B, ALA4A, ASP107B, ASP6A, ASP7A, CYS29A, GLN139B, GLN39A, GLU153B, GLU53A, GLU9A, GLY140B, GLY33A, GLY40A, HIS145B, HIS150B, HIS152B, HIS45A, HIS52A, ILE103B, ILE147B, ILE151B, ILE35A, ILE3A, ILE47A, ILE51A, LEU108B, LEU143B, LEU144B, LEU30A, LEU36A, LEU43A, LEU44A, LEU8A, LYS148B, LYS149B, LYS32A, LYS48A, LYS49A, MET1A, PHE146B, PHE46A, SER141B, SER41A, THR10A, THR137B, THR142B, THR37A, THR42A, THR5A, VAL102B, VAL2A, VAL34A
• A-C: ALA204C, ALA238C, ALA38A, ALA4A, ASP206C, ASP207C, ASP7A, CYS229C, GLN239C, GLN39A, GLU209C, GLU253C, GLU53A, GLY231C, GLY233C, GLY240C, GLY40A, HIS245C, HIS252C, HIS45A, HIS50A, HIS52A, ILE203C, ILE235C, ILE247C, ILE251C, ILE3A, ILE47A, ILE51A, LEU208C, LEU230C, LEU236C, LEU243C, LEU244C, LEU43A, LEU44A, LEU8A, LYS232C, LYS248C, LYS249C, LYS48A, LYS49A, MET1A, MET201C, PHE246C, PHE46A, SER241C, SER41A, THR205C, THR210C, THR211C, THR237C, THR242C, THR37A, THR42A, VAL202C, VAL234C, VAL2A
• A-D: ALA4A, ARG20D, ASP6A, ASP7A, GLU21D, GLU22D, GLU24D, GLU53A, GLU53D, GLU9A, ILE3A, LEU8A, MET1A, PRO23D, PRO25D, PRO27D, THR5A
• A-E: GLU153E, GLU53A
• A-F: GLU253F, GLU53A
• A-G: GLU53A, HIS50A, HIS50G, HIS52A, HIS52G, ILE51A, ILE51G
• A-I: GLU253I, GLU53A, HIS245I, HIS252I, HIS50A, HIS52A, ILE251I, ILE51A, LEU230I, LYS248I, LYS249I, LYS48A, LYS49A, PHE46A
• A-J: ALA38A, ALA38J, ARG20A, ARG20J, CYS26A, CYS26J, CYS29A, CYS29J, GLN39A, GLN39J, GLU21A, GLU21J, GLU24A, GLU24J, GLU53A, GLU53J, GLY19A, GLY19J, GLY31A, GLY31J, GLY40A, GLY40J, HIS45A, HIS45J, ILE35A, ILE35J, ILE47A, ILE47J, LEU30A, LEU30J, LEU36A, LEU36J, LEU43A, LEU43J, LEU44A, LEU44J, LYS28A, LYS28J, LYS32A, LYS32J, LYS48A, LYS48J, LYS49A, LYS49J, PHE46A, PHE46J, PRO23A, PRO23J, PRO25A, PRO25J, PRO27A, PRO27J, SER41A, SER41J, THR37A, THR37J, THR42A, THR42J
• A-K: GLU153K, GLU53A, HIS150K, HIS152K, HIS45A, HIS52A, ILE151K, ILE51A, LEU30A, LYS149K, LYS48A, LYS49A, PHE146K
• A-L: ALA204L, ARG20A, ASP206L, ASP207L, GLU209L, GLU21A, GLU22A, GLU24A, GLU253L, GLU53A, ILE203L, LEU208L, MET201L, PRO23A, PRO25A, PRO27A, THR205L
• A-e: ILE3A, ILE3e, MET1A, MET1e, VAL2A, VAL2e
• A-f: ALA138f, ASP107f, ASP7A, GLN139f, GLN39A, ILE103f, MET1A, VAL102f, VAL2A
• B-C: ALA104B, ALA204C, ALA238C, ASP106B, ASP107B, ASP207C, CYS129B, GLN139B, GLN239C, GLU109B, GLU153B, GLU253C, GLY131B, GLY133B, GLY140B, GLY240C, HIS145B, HIS152B, HIS245C, HIS250C, HIS252C, ILE103B, ILE135B, ILE147B, ILE151B, ILE203C, ILE247C, ILE251C, LEU108B, LEU130B, LEU136B, LEU143B, LEU144B, LEU208C, LEU243C, LEU244C, LYS132B, LYS148B, LYS149B, LYS248C, LYS249C, MET101B, MET201C, PHE146B, PHE246C, SER141B, SER241C, THR105B, THR110B, THR137B, THR142B, THR237C, THR242C, VAL102B, VAL134B, VAL202C
• B-D: ALA138B, ALA38D, ARG120B, ARG20D, ASN14D, CYS126B, CYS129B, CYS26D, CYS29D, GLN139B, GLN39D, GLU121B, GLU124B, GLU153B, GLU21D, GLU24D, GLU53D, GLY119B, GLY131B, GLY140B, GLY19D, GLY31D, GLY40D, HIS145B, HIS45D, ILE135B, ILE147B, ILE35D, ILE47D, LEU130B, LEU136B, LEU143B, LEU144B, LEU30D, LEU36D, LEU43D, LEU44D, LYS128B, LYS132B, LYS148B, LYS149B, LYS28D, LYS32D, LYS48D, LYS49D, PHE146B, PHE46D, PRO113B, PRO123B, PRO125B, PRO127B, PRO13D, PRO23D, PRO25D, PRO27D, SER141B, SER41D, THR137B, THR142B, THR37D, THR42D
• B-E: GLU153B, GLU153E, HIS145B, HIS150E, HIS152B, HIS152E, ILE151B, ILE151E, LEU130B, LEU144B, LYS132B, LYS148B, LYS148E, LYS149B, LYS149E, PHE146E
• B-F: ALA204F, ARG120B, ASP206F, ASP207F, GLU121B, GLU124B, GLU209F, ILE203F, LEU208F, MET201F, PRO123B, PRO125B, PRO127B, THR205F
• B-I: ALA104B, ARG220I, ASP106B, ASP107B, GLU109B, GLU153B, GLU221I, GLU222I, GLU224I, GLU253I, ILE103B, LEU108B, MET101B, PRO223I, PRO225I, PRO227I, THR105B
• B-J: GLU153B, GLU53J, HIS150B, HIS152B, HIS45J, HIS52J, ILE151B, ILE47J, ILE51J, LEU30J, LEU44J, LYS149B, LYS32J, LYS48J, LYS49J, PHE146B
• B-K: GLU153B, GLU153K, HIS150B, HIS150K, HIS152B, HIS152K, ILE151B, ILE151K
• B-L: GLU153B, GLU253L
• B-R: ARG120B, ASN114B, ASN116B, ASN214R, CYS112B, CYS115B, CYS212R, CYS215R, CYS226R, CYS229R, GLU121B, GLU122B, GLU221R, GLY117B, ILE235R, LYS228R, PRO113B, PRO213R, PRO227R, SER118B, THR111B
• B-S: ASN114B, ASN116B, ASN14S, ASN16S, CYS112B, CYS115B, CYS126B, CYS12S, CYS15S, GLU121B, ILE135B, ILE35S, LEU36S, LYS128B, LYS28S, PRO113B, PRO127B, PRO13S, THR10S, THR11S, THR37S
• B-e: ASP107B, GLN139B, ILE103B, ILE3e, MET101B, MET1e, VAL102B, VAL2e
• B-f: ILE103B, ILE103f, MET101B, MET101f, VAL102B, VAL102f
• B-g: ALA104B, ILE103B, ILE203g, MET101B, MET201g, VAL102B, VAL202g
• C-D: GLU253C, GLU53D, HIS250C, HIS252C, HIS45D, HIS52D, ILE251C, ILE51D, LEU30D, LYS248C, LYS249C, LYS48D, LYS49D, PHE246C
• C-E: GLU153E, GLU253C, HIS150E, HIS152E, HIS250C, HIS252C, ILE151E, ILE251C
• C-F: GLU253C, GLU253F
• C-G: GLU253C, HIS245C, HIS252C, HIS50G, HIS52G, ILE251C, ILE51G, LEU230C, LYS232C, LYS248C, LYS249C, LYS48G, LYS49G, PHE46G
• C-H: ALA104H, ARG220C, ASP106H, ASP107H, GLU109H, GLU221C, GLU222C, GLU224C, GLU253C, ILE103H, ILE151H, LEU108H, MET101H, PRO223C, PRO225C, PRO227C, THR105H
• C-I: ALA238C, ALA238I, ARG220C, ARG220I, CYS226C, CYS226I, CYS229C, CYS229I, GLN239C, GLN239I, GLU221C, GLU221I, GLU224C, GLU224I, GLU253C, GLU253I, GLY219C, GLY219I, GLY231C, GLY231I, GLY240C, GLY240I, HIS245C, HIS245I, ILE235C, ILE235I, ILE247C, ILE247I, LEU230C, LEU230I, LEU236C, LEU236I, LEU243C, LEU243I, LEU244C, LEU244I, LYS228C, LYS228I, LYS232C, LYS232I, LYS248C, LYS248I, LYS249C, LYS249I, PHE246C, PHE246I, PRO213C, PRO223C, PRO223I, PRO225C, PRO225I, PRO227C, PRO227I, SER241C, SER241I, THR237C, THR237I, THR242C, THR242I
• C-J: ALA204C, ARG20J, ASP206C, ASP207C, GLU209C, GLU21J, GLU22J, GLU24J, GLU253C, GLU53J, ILE203C, LEU208C, MET201C, PRO23J, PRO25J, PRO27J, THR205C
• C-K: GLU153K, GLU253C
• C-L: GLU253C, GLU253L
• C-Z: ASN216C, GLU121Z, GLU124Z, GLU221C, GLU222C, PRO123Z, SER218C
• C-4: ALA2044, ARG220C, ASP2064, GLU222C, MET2014, SER218C
• C-e: ILE203C, VAL202C, VAL2e
• C-f: ALA104f, ALA204C, ASP107f, ASP207C, ILE103f, ILE203C, MET101f, MET201C, VAL102f, VAL202C
• C-g: GLN239C, GLN239g, VAL202C, VAL202g
• D-E: ALA104E, ALA138E, ALA4D, ASP107E, ASP6D, ASP7D, CYS29D, GLN139E, GLN39D, GLU153E, GLU53D, GLU9D, GLY140E, GLY31D, GLY33D, GLY40D, HIS145E, HIS150E, HIS152E, HIS45D, HIS50D, HIS52D, ILE103E, ILE147E, ILE151E, ILE35D, ILE3D, ILE47D, ILE51D, LEU108E, LEU143E, LEU144E, LEU30D, LEU36D, LEU43D, LEU44D, LEU8D, LYS148E, LYS149E, LYS32D, LYS48D, LYS49D, MET1D, PHE146E, PHE46D, SER141E, SER41D, THR10D, THR137E, THR142E, THR37D, THR42D, THR5D, VAL102E, VAL2D, VAL34D
• D-F: ALA204F, ALA38D, ALA4D, ASP206F, ASP207F, ASP7D, CYS229F, GLN239F, GLN39D, GLU209F, GLU253F, GLU53D, GLY231F, GLY233F, GLY240F, GLY40D, HIS245F, HIS250F, HIS252F, HIS45D, HIS50D, HIS52D, ILE203F, ILE235F, ILE247F, ILE251F, ILE3D, ILE47D, ILE51D, LEU208F, LEU230F, LEU236F, LEU243F, LEU244F, LEU43D, LEU44D, LEU8D, LYS232F, LYS248F, LYS249F, LYS48D, LYS49D, MET1D, MET201F, PHE246F, PHE46D, SER241F, SER41D, THR205F, THR210F, THR237F, THR242F, THR37D, THR42D, VAL202F, VAL234F, VAL2D
• D-G: GLU53D, HIS45G, HIS50D, HIS52D, HIS52G, ILE51D, ILE51G, LEU30G, LEU44G, LYS48D, LYS48G, LYS49D, LYS49G, PHE46D
• D-H: GLU53D, HIS150H, HIS152H, HIS50D, HIS52D, ILE151H, ILE51D
• D-I: GLU253I, GLU53D, ILE251I
• D-J: GLU53D, GLU53J, ILE51D
• D-K: GLU153K, GLU53D
• D-L: ALA4D, ARG220L, ASP6D, ASP7D, GLU222L, GLU224L, GLU253L, GLU53D, GLU9D, ILE3D, LEU8D, MET1D, PRO223L, PRO225L, PRO227L, THR5D
• D-S: ALA38D, ASN14D, ASN14S, ASN16S, CYS12D, CYS12S, CYS15S, GLY17S, ILE35D, LEU36D, LYS28D, PRO13D, PRO13S, SER18S, THR10D, THR11D, THR11S, THR37D
• E-F: ALA104E, ALA204F, ALA238F, ASP106E, ASP107E, ASP207F, CYS129E, GLN139E, GLN239F, GLU109E, GLU153E, GLU253F, GLY131E, GLY133E, GLY140E, GLY240F, HIS145E, HIS152E, HIS245F, HIS250F, HIS252F, ILE103E, ILE135E, ILE147E, ILE151E, ILE203F, ILE247F, ILE251F, LEU108E, LEU130E, LEU136E, LEU143E, LEU144E, LEU208F, LEU243F, LEU244F, LYS132E, LYS148E, LYS149E, LYS248F, LYS249F, MET101E, MET201F, PHE146E, PHE246F, SER141E, SER241F, THR105E, THR110E, THR137E, THR142E, THR237F, THR242F, VAL102E, VAL134E, VAL202F
• E-G: ALA104E, ARG20G, ASP106E, ASP107E, GLU109E, GLU153E, GLU21G, GLU22G, GLU24G, HIS52G, ILE103E, LEU108E, MET101E, PRO23G, PRO25G, PRO27G, THR105E
• E-I: GLU153E, GLU253I
• E-J: GLU153E, GLU53J, HIS145E, HIS152E, HIS50J, HIS52J, ILE151E, ILE51J, LEU130E, LEU144E, LYS148E, LYS149E, LYS48J, LYS49J, PHE46J
• E-K: ALA104K, ARG120E, ASP106K, ASP107K, GLU109K, GLU121E, GLU122E, GLU124E, GLU153E, GLU153K, ILE103K, LEU108K, MET101K, PRO123E, PRO125E, PRO127E, THR105K
• E-L: ALA138E, ALA238L, ARG120E, ARG220L, ASN214L, CYS126E, CYS129E, CYS226L, CYS229L, GLN139E, GLN239L, GLU121E, GLU124E, GLU153E, GLU221L, GLU224L, GLU253L, GLY119E, GLY131E, GLY140E, GLY219L, GLY231L, GLY240L, HIS145E, HIS245L, ILE135E, ILE147E, ILE235L, ILE247L, LEU130E, LEU136E, LEU143E, LEU144E, LEU230L, LEU236L, LEU243L, LEU244L, LYS128E, LYS132E, LYS148E, LYS149E, LYS228L, LYS232L, LYS248L, LYS249L, PHE146E, PHE246L, PRO123E, PRO125E, PRO127E, PRO223L, PRO225L, PRO227L, SER141E, SER241L, THR137E, THR142E, THR237L, THR242L
• F-G: ALA238F, ALA38G, ARG20G, ARG220F, ASN14G, ASN214F, CYS226F, CYS229F, CYS26G, CYS29G, GLN239F, GLN39G, GLU21G, GLU221F, GLU224F, GLU24G, GLU253F, GLY19G, GLY219F, GLY231F, GLY240F, GLY31G, GLY40G, HIS245F, HIS45G, HIS52G, ILE235F, ILE247F, ILE35G, ILE47G, ILE51G, LEU230F, LEU236F, LEU243F, LEU244F, LEU30G, LEU36G, LEU43G, LEU44G, LYS228F, LYS232F, LYS248F, LYS249F, LYS28G, LYS32G, LYS48G, LYS49G, PHE246F, PHE46G, PRO13G, PRO213F, PRO223F, PRO225F, PRO227F, PRO23G, PRO25G, PRO27G, SER241F, SER41G, THR237F, THR242F, THR37G, THR42G
• F-H: GLU253F, HIS150H, HIS152H, HIS245F, HIS252F, ILE151H, ILE251F, LEU230F, LYS148H, LYS149H, LYS232F, LYS248F, LYS249F, PHE146H
• F-I: ALA204I, ARG220F, ASP206I, ASP207I, GLU209I, GLU221F, GLU222F, GLU224F, GLU253F, GLU253I, ILE203I, ILE251I, LEU208I, MET201I, PRO223F, PRO225F, PRO227F, THR205I
• F-J: GLU253F, GLU53J, HIS250F, HIS252F, HIS50J, HIS52J, ILE251F, ILE51J
• F-L: GLU253F, GLU253L, HIS245L, HIS250F, HIS252F, HIS252L, ILE251F, ILE251L, LEU230L, LYS232L, LYS248F, LYS248L, LYS249F, LYS249L, PHE246F
• G-H: ALA104H, ALA138H, ALA4G, ASP107H, ASP6G, ASP7G, CYS29G, GLN139H, GLN39G, GLU9G, GLY140H, GLY31G, GLY33G, GLY40G, HIS145H, HIS150H, HIS152H, HIS45G, HIS52G, ILE103H, ILE147H, ILE151H, ILE35G, ILE3G, ILE47G, ILE51G, LEU108H, LEU143H, LEU144H, LEU30G, LEU36G, LEU43G, LEU44G, LEU8G, LYS148H, LYS149H, LYS32G, LYS48G, LYS49G, MET101H, MET1G, PHE146H, PHE46G, SER141H, SER41G, THR10G, THR137H, THR142H, THR37G, THR42G, THR5G, VAL102H, VAL2G, VAL34G
• G-I: ALA204I, ALA38G, ALA4G, ASP206I, ASP207I, ASP7G, CYS229I, GLN239I, GLN39G, GLU209I, GLU253I, GLY233I, GLY240I, GLY40G, HIS245I, HIS250I, HIS252I, HIS45G, HIS50G, HIS52G, ILE203I, ILE235I, ILE247I, ILE251I, ILE3G, ILE47G, ILE51G, LEU208I, LEU230I, LEU236I, LEU243I, LEU244I, LEU43G, LEU44G, LEU8G, LYS232I, LYS248I, LYS249I, LYS48G, LYS49G, MET1G, MET201I, PHE246I, PHE46G, SER241I, SER41G, THR205I, THR210I, THR237I, THR242I, THR37G, THR42G, VAL202I, VAL234I, VAL2G
• G-K: ALA4G, ARG120K, ASP6G, ASP7G, GLU121K, GLU124K, GLU9G, ILE3G, LEU8G, MET1G, PRO123K, PRO125K, PRO127K, THR5G
• H-I: ALA104H, ALA204I, ALA238I, ASP106H, ASP107H, ASP207I, CYS129H, GLN139H, GLN239I, GLU109H, GLU253I, GLY133H, GLY140H, GLY240I, HIS145H, HIS152H, HIS245I, HIS250I, HIS252I, ILE103H, ILE135H, ILE147H, ILE151H, ILE203I, ILE247I, ILE251I, LEU108H, LEU130H, LEU136H, LEU143H, LEU144H, LEU208I, LEU243I, LEU244I, LYS132H, LYS148H, LYS149H, LYS248I, LYS249I, MET101H, MET201I, PHE146H, PHE246I, SER141H, SER241I, THR105H, THR110H, THR137H, THR142H, THR237I, THR242I, VAL102H, VAL134H, VAL202I
• H-J: ALA4J, ARG120H, ASP6J, ASP7J, GLU121H, GLU124H, GLU9J, ILE3J, LEU8J, MET1J, PRO123H, PRO125H, PRO127H, THR5J
• H-K: ALA138H, ALA138K, ARG120H, ARG120K, ASN114H, ASN114K, CYS126H, CYS126K, CYS129H, CYS129K, GLN139H, GLN139K, GLU121H, GLU121K, GLU124H, GLU124K, GLY119H, GLY119K, GLY131H, GLY131K, GLY140H, GLY140K, HIS145H, HIS145K, ILE135H, ILE135K, ILE147H, ILE147K, LEU130H, LEU130K, LEU136H, LEU136K, LEU143H, LEU143K, LEU144H, LEU144K, LYS128H, LYS128K, LYS132H, LYS132K, LYS148H, LYS148K, LYS149H, LYS149K, PHE146H, PHE146K, PRO113H, PRO113K, PRO123H, PRO123K, PRO125H, PRO125K, PRO127H, PRO127K, SER141H, SER141K, THR137H, THR137K, THR142H, THR142K
• H-L: GLU253L, HIS145H, HIS152H, HIS250L, HIS252L, ILE151H, ILE251L, LEU130H, LYS148H, LYS149H, LYS248L, LYS249L, PHE246L
• H-2: ALA42, ARG120H, ASN114H, ASN116H, ASP72, CYS112H, CYS115H, GLU121H, GLU122H, GLY117H, GLY119H, ILE32, MET12, SER118H, THR111H, VAL22
• H-3: ALA1043, ASN114H, ASN116H, ASP1063, ASP1073, CYS112H, CYS115H, GLN1393, GLY117H, ILE1033, MET1013, PRO113H, SER118H, THR111H, VAL1023
• H-4: ASN116H, GLY117H, SER118H, THR111H, VAL2024
• H-a: GLU122H, PRO223a
• I-J: GLU253I, GLU53J
• I-K: GLU153K, GLU253I, HIS145K, HIS152K, HIS250I, HIS252I, ILE151K, ILE251I, LEU130K, LYS132K, LYS148K, LYS149K, LYS248I, LYS249I, PHE246I
• I-L: GLU253I, GLU253L, HIS250I, HIS250L, HIS252I, HIS252L, ILE251I, ILE251L
• J-K: ALA138K, ALA38J, ALA4J, ASP107K, ASP6J, ASP7J, CYS29J, GLN139K, GLN39J, GLU153K, GLU53J, GLU9J, GLY140K, GLY33J, GLY40J, HIS145K, HIS150K, HIS152K, HIS45J, HIS52J, ILE103K, ILE147K, ILE151K, ILE35J, ILE3J, ILE47J, ILE51J, LEU108K, LEU143K, LEU144K, LEU30J, LEU36J, LEU43J, LEU44J, LEU8J, LYS148K, LYS149K, LYS32J, LYS48J, LYS49J, MET1J, PHE146K, PHE46J, SER141K, SER41J, THR10J, THR11J, THR137K, THR142K, THR37J, THR42J, THR5J, VAL102K, VAL2J, VAL34J
• J-L: ALA204L, ALA38J, ALA4J, ASP206L, ASP207L, ASP7J, CYS229L, GLN239L, GLN39J, GLU209L, GLU253L, GLU53J, GLY233L, GLY240L, GLY40J, HIS245L, HIS252L, HIS45J, HIS50J, HIS52J, ILE203L, ILE235L, ILE247L, ILE251L, ILE3J, ILE47J, ILE51J, LEU208L, LEU230L, LEU236L, LEU243L, LEU244L, LEU43J, LEU44J, LEU8J, LYS232L, LYS248L, LYS249L, LYS48J, LYS49J, MET201L, PHE246L, PHE46J, SER241L, SER41J, THR205L, THR210L, THR211L, THR237L, THR242L, THR37J, THR42J, VAL202L, VAL234L, VAL2J
• K-L: ALA104K, ALA204L, ALA238L, ASP106K, ASP107K, ASP207L, CYS129K, GLN139K, GLN239L, GLU109K, GLU153K, GLU253L, GLY133K, GLY140K, GLY240L, HIS145K, HIS150K, HIS152K, HIS245L, HIS250L, HIS252L, ILE103K, ILE135K, ILE147K, ILE151K, ILE203L, ILE247L, ILE251L, LEU108K, LEU130K, LEU136K, LEU143K, LEU144K, LEU208L, LEU243L, LEU244L, LYS132K, LYS148K, LYS149K, LYS248L, LYS249L, MET101K, MET201L, PHE146K, PHE246L, SER141K, SER241L, THR105K, THR110K, THR137K, THR142K, THR237L, THR242L, VAL102K, VAL134K, VAL202L
• M-N: ALA104N, ALA138N, ALA4M, ASP107N, ASP6M, ASP7M, CYS29M, GLN139N, GLN39M, GLU53M, GLU9M, GLY140N, GLY31M, GLY33M, GLY40M, HIS145N, HIS150N, HIS152N, HIS45M, HIS52M, ILE103N, ILE147N, ILE151N, ILE35M, ILE3M, ILE47M, ILE51M, LEU108N, LEU143N, LEU144N, LEU30M, LEU36M, LEU43M, LEU44M, LEU8M, LYS148N, LYS149N, LYS32M, LYS48M, LYS49M, MET101N, MET1M, PHE146N, PHE46M, SER141N, SER41M, THR10M, THR137N, THR142N, THR37M, THR42M, THR5M, VAL102N, VAL2M, VAL34M
• M-O: ALA204O, ALA38M, ALA4M, ASP206O, ASP207O, ASP7M, CYS229O, GLN239O, GLN39M, GLU209O, GLU253O, GLU53M, GLY231O, GLY233O, GLY240O, GLY40M, HIS245O, HIS252O, HIS45M, HIS50M, HIS52M, ILE203O, ILE235O, ILE247O, ILE251O, ILE3M, ILE47M, ILE51M, LEU208O, LEU230O, LEU236O, LEU243O, LEU244O, LEU43M, LEU44M, LEU8M, LYS232O, LYS248O, LYS249O, LYS48M, LYS49M, MET1M, MET201O, PHE246O, PHE46M, SER241O, SER41M, THR205O, THR210O, THR211O, THR237O, THR242O, THR37M, THR42M, VAL202O, VAL234O, VAL2M
• M-P: ALA4M, ARG20P, ASP6M, ASP7M, GLU22P, GLU24P, GLU9M, ILE3M, LEU8M, MET1M, PRO23P, PRO25P, PRO27P, THR5M
• M-S: GLU53M, GLU53S, HIS50M, HIS50S, HIS52M, HIS52S, ILE51M, ILE51S
• M-T: GLU153T, GLU53M
• M-U: GLU253U, GLU53M, HIS245U, HIS252U, HIS50M, HIS52M, ILE251U, ILE51M, LEU230U, LYS232U, LYS248U, LYS249U, LYS48M, LYS49M, PHE46M
• M-V: ALA38M, ALA38V, ARG20M, ARG20V, ASN14M, ASN14V, CYS26M, CYS26V, CYS29M, CYS29V, GLN39M, GLN39V, GLU21M, GLU21V, GLU24M, GLU24V, GLU53M, GLU53V, GLY19M, GLY19V, GLY31M, GLY31V, GLY40M, GLY40V, HIS45M, HIS45V, ILE35M, ILE35V, ILE47M, ILE47V, LEU30M, LEU30V, LEU36M, LEU36V, LEU43M, LEU43V, LEU44M, LEU44V, LYS28M, LYS28V, LYS32M, LYS32V, LYS48M, LYS48V, LYS49M, LYS49V, PHE46M, PHE46V, PRO13M, PRO13V, PRO23M, PRO23V, PRO25M, PRO25V, PRO27M, PRO27V, SER41M, SER41V, THR37M, THR37V, THR42M, THR42V
• M-W: GLU153W, GLU53M, HIS150W, HIS152W, HIS45M, HIS52M, ILE151W, ILE51M, LEU30M, LYS148W, LYS149W, LYS48M, LYS49M, PHE146W
• M-X: ALA204X, ARG20M, ASP206X, ASP207X, GLU209X, GLU21M, GLU24M, GLU253X, GLU53M, ILE203X, ILE251X, LEU208X, MET201X, PRO23M, PRO25M, PRO27M, THR205X
• N-O: ALA104N, ALA204O, ALA238O, ASP106N, ASP107N, ASP207O, CYS129N, GLN139N, GLN239O, GLU109N, GLU253O, GLY133N, GLY140N, GLY240O, HIS145N, HIS152N, HIS245O, HIS250O, HIS252O, ILE103N, ILE135N, ILE147N, ILE151N, ILE203O, ILE247O, ILE251O, LEU108N, LEU130N, LEU136N, LEU143N, LEU144N, LEU208O, LEU243O, LEU244O, LYS132N, LYS148N, LYS149N, LYS248O, LYS249O, MET101N, MET201O, PHE146N, PHE246O, SER141N, SER241O, THR105N, THR110N, THR137N, THR142N, THR237O, THR242O, VAL102N, VAL134N, VAL202O
• N-P: ALA138N, ALA38P, ARG120N, ARG20P, ASN114N, CYS126N, CYS129N, CYS26P, CYS29P, GLN139N, GLN39P, GLU121N, GLU124N, GLU21P, GLU24P, GLU53P, GLY119N, GLY131N, GLY140N, GLY19P, GLY31P, GLY40P, HIS145N, HIS152N, HIS45P, ILE135N, ILE147N, ILE35P, ILE47P, LEU130N, LEU136N, LEU143N, LEU144N, LEU30P, LEU36P, LEU43P, LEU44P, LYS128N, LYS132N, LYS148N, LYS149N, LYS28P, LYS32P, LYS48P, LYS49P, PHE146N, PHE46P, PRO123N, PRO125N, PRO127N, PRO23P, PRO25P, PRO27P, SER141N, SER41P, THR137N, THR142N, THR37P, THR42P
• N-Q: GLU153Q, HIS145N, HIS150Q, HIS152N, HIS152Q, ILE151N, ILE151Q, LEU130N, LEU144N, LYS148N, LYS148Q, LYS149N, LYS149Q, PHE146Q
• N-R: ALA204R, ARG120N, ASP206R, ASP207R, GLU121N, GLU124N, GLU209R, ILE203R, LEU208R, MET201R, PRO123N, PRO125N, PRO127N, THR205R
• N-U: ALA104N, ARG220U, ASP106N, ASP107N, GLU109N, GLU221U, GLU222U, GLU224U, ILE103N, LEU108N, MET101N, PRO223U, PRO225U, PRO227U, THR105N
• N-V: GLU53V, HIS150N, HIS152N, HIS52V, ILE151N, ILE51V, LEU30V, LYS149N, LYS48V, LYS49V, PHE146N
• N-W: GLU153W, HIS150N, HIS150W, HIS152N, HIS152W, ILE151N, ILE151W
• O-P: GLU253O, GLU53P, HIS250O, HIS252O, HIS45P, HIS52P, ILE251O, ILE51P, LEU30P, LEU44P, LYS248O, LYS249O, LYS32P, LYS48P, LYS49P, PHE246O
• O-Q: GLU153Q, GLU253O, HIS150Q, HIS152Q, HIS250O, HIS252O, ILE151Q, ILE251O
• O-R: GLU253O, GLU253R
• O-S: GLU253O, GLU53S, HIS245O, HIS252O, HIS50S, HIS52S, ILE251O, ILE51S, LEU230O, LEU244O, LYS232O, LYS248O, LYS249O, LYS48S, LYS49S, PHE46S
• O-T: ALA104T, ARG220O, ASP106T, ASP107T, GLU109T, GLU153T, GLU224O, GLU253O, ILE103T, ILE151T, LEU108T, MET101T, PRO223O, PRO225O, PRO227O, THR105T
• O-U: ALA238O, ALA238U, ARG220O, ARG220U, ASN214U, CYS226O, CYS226U, CYS229O, CYS229U, GLN239O, GLN239U, GLU221O, GLU221U, GLU224O, GLU224U, GLU253O, GLU253U, GLY219O, GLY219U, GLY231O, GLY231U, GLY240O, GLY240U, HIS245O, HIS245U, HIS252U, ILE235O, ILE235U, ILE247O, ILE247U, LEU230O, LEU230U, LEU236O, LEU236U, LEU243O, LEU243U, LEU244O, LEU244U, LYS228O, LYS228U, LYS232O, LYS232U, LYS248O, LYS248U, LYS249O, LYS249U, PHE246O, PHE246U, PRO223O, PRO223U, PRO225O, PRO225U, PRO227O, PRO227U, SER241O, SER241U, THR237O, THR237U, THR242O, THR242U
• O-V: ALA204O, ARG20V, ASP206O, ASP207O, GLU209O, GLU21V, GLU22V, GLU24V, GLU253O, GLU53V, ILE203O, LEU208O, MET201O, PRO23V, PRO25V, PRO27V, THR205O
• O-W: GLU153W, GLU253O
• P-Q: ALA104Q, ALA138Q, ALA4P, ASP107Q, ASP6P, ASP7P, CYS29P, GLN139Q, GLN39P, GLU153Q, GLU53P, GLU9P, GLY140Q, GLY33P, GLY40P, HIS145Q, HIS150Q, HIS152Q, HIS45P, HIS50P, HIS52P, ILE103Q, ILE147Q, ILE151Q, ILE35P, ILE3P, ILE47P, ILE51P, LEU108Q, LEU143Q, LEU144Q, LEU30P, LEU36P, LEU43P, LEU44P, LEU8P, LYS148Q, LYS149Q, LYS32P, LYS48P, LYS49P, MET101Q, MET1P, PHE146Q, PHE46P, SER141Q, SER41P, THR10P, THR137Q, THR142Q, THR37P, THR42P, THR5P, VAL102Q, VAL2P, VAL34P
• P-R: ALA204R, ALA38P, ALA4P, ASP206R, ASP207R, ASP7P, CYS229R, GLN239R, GLN39P, GLU209R, GLU253R, GLU53P, GLY231R, GLY233R, GLY240R, GLY40P, HIS245R, HIS252R, HIS45P, HIS50P, HIS52P, ILE203R, ILE235R, ILE247R, ILE251R, ILE3P, ILE47P, ILE51P, LEU208R, LEU230R, LEU236R, LEU243R, LEU244R, LEU43P, LEU44P, LEU8P, LYS232R, LYS248R, LYS249R, LYS48P, LYS49P, MET201R, PHE246R, PHE46P, SER241R, SER41P, THR205R, THR210R, THR237R, THR242R, THR37P, THR42P, VAL202R, VAL234R, VAL2P
• P-S: GLU53P, GLU53S, HIS45S, HIS50P, HIS52P, HIS52S, ILE51P, ILE51S, LEU30S, LYS48P, LYS48S, LYS49P, LYS49S, PHE46P
• P-T: GLU153T, GLU53P, HIS150T, HIS152T, HIS50P, HIS52P, ILE151T, ILE51P
• P-V: GLU53P, GLU53V, ILE51P
• P-W: GLU153W, GLU53P
• P-X: ALA4P, ARG220X, ASP6P, ASP7P, GLU224X, GLU253X, GLU53P, GLU9P, ILE3P, LEU8P, MET1P, PRO223X, PRO225X, PRO227X, THR5P
• Q-R: ALA104Q, ALA138Q, ALA204R, ALA238R, ASP106Q, ASP107Q, ASP207R, CYS129Q, GLN139Q, GLN239R, GLU109Q, GLU153Q, GLU253R, GLY133Q, GLY140Q, GLY240R, HIS145Q, HIS150Q, HIS152Q, HIS245R, HIS250R, HIS252R, ILE103Q, ILE135Q, ILE147Q, ILE151Q, ILE203R, ILE247R, ILE251R, LEU108Q, LEU130Q, LEU136Q, LEU143Q, LEU144Q, LEU208R, LEU243R, LEU244R, LYS132Q, LYS148Q, LYS149Q, LYS248R, LYS249R, MET101Q, MET201R, PHE146Q, PHE246R, SER141Q, SER241R, THR105Q, THR110Q, THR137Q, THR142Q, THR237R, THR242R, VAL102Q, VAL134Q, VAL202R
• Q-S: ALA104Q, ARG20S, ASP106Q, ASP107Q, GLU109Q, GLU153Q, GLU21S, GLU24S, GLU53S, ILE103Q, ILE151Q, LEU108Q, MET101Q, PRO23S, PRO25S, PRO27S, THR105Q
• Q-T: GLU153Q, GLU153T
• Q-V: GLU153Q, GLU53V, HIS145Q, HIS152Q, HIS50V, HIS52V, ILE151Q, ILE51V, LEU130Q, LEU144Q, LYS148Q, LYS149Q, LYS48V, LYS49V, PHE46V
• Q-W: ALA104W, ARG120Q, ASP106W, ASP107W, GLU109W, GLU121Q, GLU124Q, GLU153Q, GLU153W, HIS152Q, ILE103W, LEU108W, MET101W, PRO123Q, PRO125Q, PRO127Q, THR105W
• Q-X: ALA138Q, ALA238X, ARG120Q, ARG220X, ASN214X, CYS126Q, CYS129Q, CYS226X, CYS229X, GLN139Q, GLN239X, GLU121Q, GLU124Q, GLU153Q, GLU221X, GLU224X, GLU253X, GLY119Q, GLY131Q, GLY140Q, GLY219X, GLY231X, GLY240X, HIS145Q, HIS152Q, HIS245X, HIS252X, ILE135Q, ILE147Q, ILE235X, LEU130Q, LEU136Q, LEU143Q, LEU144Q, LEU230X, LEU236X, LEU243X, LEU244X, LYS128Q, LYS132Q, LYS148Q, LYS149Q, LYS228X, LYS232X, LYS248X, LYS249X, PHE146Q, PHE246X, PRO113Q, PRO123Q, PRO125Q, PRO127Q, PRO213X, PRO223X, PRO225X, PRO227X, SER141Q, SER241X, THR137Q, THR142Q, THR237X, THR242X
• R-S: ALA238R, ALA38S, ARG20S, ARG220R, ASN214R, CYS226R, CYS229R, CYS26S, CYS29S, GLN239R, GLN39S, GLU21S, GLU221R, GLU224R, GLU24S, GLU253R, GLU53S, GLY19S, GLY219R, GLY231R, GLY240R, GLY31S, GLY40S, HIS245R, HIS45S, HIS52S, ILE235R, ILE247R, ILE35S, LEU230R, LEU236R, LEU243R, LEU244R, LEU30S, LEU36S, LEU43S, LEU44S, LYS228R, LYS232R, LYS248R, LYS249R, LYS28S, LYS32S, LYS48S, LYS49S, PHE246R, PHE46S, PRO13S, PRO213R, PRO223R, PRO225R, PRO227R, PRO23S, PRO25S, PRO27S, SER241R, SER41S, THR237R, THR242R, THR37S, THR42S
• R-T: GLU153T, GLU253R, HIS150T, HIS152T, HIS245R, HIS252R, ILE151T, ILE251R, LEU230R, LYS148T, LYS149T, LYS248R, LYS249R, PHE146T
• R-U: ALA204U, ARG220R, ASP206U, ASP207U, GLU209U, GLU221R, GLU222R, GLU224R, GLU253R, GLU253U, ILE203U, LEU208U, MET201U, PRO223R, PRO225R, PRO227R, THR205U
• R-V: GLU253R, GLU53V, HIS250R, HIS252R, HIS50V, HIS52V, ILE251R, ILE51V
• R-W: GLU153W, GLU253R
• R-X: GLU253R, GLU253X, HIS245X, HIS250R, HIS252R, HIS252X, ILE251R, ILE251X, LEU230X, LEU244X, LYS232X, LYS248R, LYS248X, LYS249R, LYS249X, PHE246R
• S-T: ALA104T, ALA138T, ALA4S, ASP107T, ASP6S, ASP7S, CYS29S, GLN139T, GLN39S, GLU153T, GLU53S, GLU9S, GLY140T, GLY33S, GLY40S, HIS145T, HIS150T, HIS152T, HIS45S, HIS52S, ILE103T, ILE147T, ILE151T, ILE35S, ILE3S, ILE47S, ILE51S, LEU108T, LEU143T, LEU144T, LEU30S, LEU36S, LEU43S, LEU44S, LEU8S, LYS148T, LYS149T, LYS32S, LYS48S, LYS49S, MET101T, MET1S, PHE146T, PHE46S, SER141T, SER41S, THR10S, THR137T, THR142T, THR37S, THR42S, THR5S, VAL102T, VAL2S, VAL34S
• S-U: ALA204U, ALA38S, ALA4S, ASP206U, ASP207U, ASP7S, CYS229U, GLN239U, GLN39S, GLU209U, GLU253U, GLU53S, GLY231U, GLY233U, GLY240U, GLY40S, HIS245U, HIS252U, HIS45S, HIS50S, HIS52S, ILE203U, ILE235U, ILE247U, ILE251U, ILE3S, ILE47S, ILE51S, LEU208U, LEU230U, LEU236U, LEU243U, LEU244U, LEU43S, LEU44S, LEU8S, LYS232U, LYS248U, LYS249U, LYS48S, LYS49S, MET1S, MET201U, PHE246U, PHE46S, SER241U, SER41S, THR205U, THR210U, THR237U, THR242U, THR37S, THR42S, VAL202U, VAL234U, VAL2S
• S-V: GLU53S, GLU53V
• S-W: ALA4S, ARG120W, ASP6S, ASP7S, GLU121W, GLU124W, GLU153W, GLU53S, GLU9S, ILE3S, LEU8S, MET1S, PRO123W, PRO125W, PRO127W, THR5S
• S-X: GLU253X, GLU53S
• S-m: ALA4S, ARG220m, ASN216m, ASP7S, CYS215m, GLU221m, GLU222m, ILE3S, MET1S, PRO223m, SER218m, VAL2S
• T-U: ALA104T, ALA204U, ALA238U, ASP106T, ASP107T, ASP207U, CYS129T, GLN139T, GLN239U, GLU109T, GLU153T, GLU253U, GLY133T, GLY140T, GLY240U, HIS145T, HIS152T, HIS245U, HIS250U, HIS252U, ILE103T, ILE135T, ILE147T, ILE151T, ILE203U, ILE247U, ILE251U, LEU108T, LEU130T, LEU136T, LEU143T, LEU144T, LEU208U, LEU243U, LEU244U, LYS132T, LYS148T, LYS149T, LYS248U, LYS249U, MET101T, MET201U, PHE146T, PHE246U, SER141T, SER241U, THR105T, THR110T, THR111T, THR137T, THR142T, THR237U, THR242U, VAL102T, VAL134T, VAL202U
• T-V: ALA4V, ARG120T, ASP6V, ASP7V, GLU121T, GLU124T, GLU153T, GLU53V, GLU9V, ILE3V, ILE51V, LEU8V, MET1V, PRO123T, PRO125T, PRO127T, THR5V
• T-W: ALA138T, ALA138W, ARG120T, ARG120W, ASN114W, CYS126T, CYS126W, CYS129T, CYS129W, GLN139T, GLN139W, GLU121T, GLU121W, GLU124T, GLU124W, GLU153T, GLU153W, GLY119T, GLY119W, GLY131T, GLY131W, GLY140T, GLY140W, HIS145T, HIS145W, ILE135T, ILE135W, ILE147T, ILE147W, LEU130T, LEU130W, LEU136T, LEU136W, LEU143T, LEU143W, LEU144T, LEU144W, LYS128T, LYS128W, LYS132T, LYS132W, LYS148T, LYS148W, LYS149T, LYS149W, PHE146T, PHE146W, PRO113W, PRO123T, PRO123W, PRO125T, PRO125W, PRO127T, PRO127W, SER141T, SER141W, THR137T, THR137W, THR142T, THR142W
• T-X: GLU153T, GLU253X, HIS145T, HIS152T, HIS250X, HIS252X, ILE151T, ILE251X, LEU130T, LYS148T, LYS149T, LYS248X, LYS249X, PHE246X
• T-e: ARG20e, ASN16e, CYS15e, GLY17e, GLY19e, MET101T, SER18e, THR11e, VAL102T
• T-m: ALA138T, ASN216m, GLN139T, GLU222m
• U-V: GLU253U, GLU53V
• U-W: GLU153W, GLU253U, HIS145W, HIS152W, HIS250U, HIS252U, ILE151W, ILE251U, LEU130W, LYS148W, LYS149W, LYS249U, PHE246U
• U-X: GLU253U, GLU253X, HIS250U, HIS250X, HIS252U, HIS252X, ILE251U, ILE251X
• U-e: ALA204U, ASN16e, ASP206U, ASP207U, THR11e, VAL202U
• U-m: GLU222m, PRO223m, VAL202U
• V-W: ALA104W, ALA138W, ALA4V, ASP107W, ASP6V, ASP7V, CYS29V, GLN139W, GLN39V, GLU153W, GLU53V, GLU9V, GLY140W, GLY31V, GLY33V, GLY40V, HIS145W, HIS150W, HIS152W, HIS45V, HIS50V, HIS52V, ILE103W, ILE147W, ILE151W, ILE35V, ILE3V, ILE47V, ILE51V, LEU108W, LEU143W, LEU144W, LEU30V, LEU36V, LEU43V, LEU44V, LEU8V, LYS148W, LYS149W, LYS32V, LYS48V, LYS49V, MET101W, MET1V, PHE146W, PHE46V, SER141W, SER41V, THR10V, THR137W, THR142W, THR37V, THR42V, THR5V, VAL102W, VAL2V, VAL34V
• V-X: ALA204X, ALA38V, ALA4V, ASP206X, ASP207X, ASP7V, CYS229X, GLN239X, GLN39V, GLU209X, GLU253X, GLU53V, GLY233X, GLY240X, GLY40V, HIS245X, HIS252X, HIS45V, HIS50V, HIS52V, ILE203X, ILE235X, ILE247X, ILE251X, ILE3V, ILE47V, ILE51V, LEU208X, LEU230X, LEU236X, LEU243X, LEU244X, LEU43V, LEU44V, LEU8V, LYS232X, LYS248X, LYS249X, LYS48V, LYS49V, MET201X, PHE246X, PHE46V, SER241X, SER41V, THR205X, THR210X, THR211X, THR237X, THR242X, THR37V, THR42V, VAL202X, VAL234X, VAL2V
• W-X: ALA104W, ALA204X, ALA238X, ASP106W, ASP107W, ASP207X, CYS129W, GLN139W, GLN239X, GLU109W, GLU153W, GLU253X, GLY133W, GLY140W, GLY240X, HIS145W, HIS152W, HIS245X, HIS250X, HIS252X, ILE103W, ILE135W, ILE147W, ILE151W, ILE203X, ILE247X, ILE251X, LEU108W, LEU130W, LEU136W, LEU143W, LEU144W, LEU208X, LEU243X, LEU244X, LYS132W, LYS148W, LYS149W, LYS248X, LYS249X, MET101W, MET201X, PHE146W, PHE246X, SER141W, SER241X, THR105W, THR110W, THR137W, THR142W, THR237X, THR242X, VAL102W, VAL134W, VAL202X
• W-m: ASN216m, GLU121W, GLU122W, PRO123W, PRO127W
• Y-Z: ALA104Z, ALA138Z, ALA4Y, ASP107Z, ASP6Y, ASP7Y, CYS29Y, GLN139Z, GLN39Y, GLU53Y, GLU9Y, GLY140Z, GLY31Y, GLY33Y, GLY40Y, HIS145Z, HIS150Z, HIS152Z, HIS45Y, HIS52Y, ILE103Z, ILE147Z, ILE151Z, ILE35Y, ILE3Y, ILE47Y, ILE51Y, LEU108Z, LEU143Z, LEU144Z, LEU30Y, LEU36Y, LEU43Y, LEU44Y, LEU8Y, LYS148Z, LYS149Z, LYS32Y, LYS48Y, LYS49Y, MET1Y, PHE146Z, PHE46Y, SER141Z, SER41Y, THR10Y, THR137Z, THR142Z, THR37Y, THR42Y, THR5Y, VAL102Z, VAL2Y, VAL34Y
• Y-1: ALA2041, ALA38Y, ALA4Y, ASP2061, ASP2071, ASP7Y, CYS2291, GLN2391, GLN39Y, GLU2091, GLU2531, GLU53Y, GLY2311, GLY2331, GLY2401, GLY40Y, HIS2451, HIS2521, HIS45Y, HIS50Y, HIS52Y, ILE2031, ILE2351, ILE2471, ILE2511, ILE3Y, ILE47Y, ILE51Y, LEU2081, LEU2301, LEU2361, LEU2431, LEU2441, LEU43Y, LEU44Y, LEU8Y, LYS2321, LYS2481, LYS2491, LYS48Y, LYS49Y, MET1Y, MET2011, PHE2461, PHE46Y, SER2411, SER41Y, THR2051, THR2101, THR2371, THR2421, THR37Y, THR42Y, VAL2021, VAL2341, VAL2Y
• Y-2: ALA4Y, ARG202, ASP6Y, ASP7Y, GLU212, GLU222, GLU242, GLU9Y, ILE3Y, LEU8Y, MET1Y, PRO232, PRO252, PRO272, THR5Y
• Y-3: GLU1533, GLU53Y, ILE51Y
• Y-5: GLU535, GLU53Y, HIS505, HIS50Y, HIS525, HIS52Y, ILE515, ILE51Y
• Y-6: GLU1536, GLU53Y
• Y-7: GLU2537, GLU53Y, HIS2457, HIS2527, HIS50Y, HIS52Y, ILE2517, ILE51Y, LEU2307, LEU2447, LYS2327, LYS2487, LYS2497, LYS48Y, LYS49Y, PHE46Y
• Y-8: ALA388, ALA38Y, ARG208, ARG20Y, ASN14Y, CYS268, CYS26Y, CYS298, CYS29Y, GLN398, GLN39Y, GLU218, GLU21Y, GLU248, GLU24Y, GLU538, GLU53Y, GLY198, GLY19Y, GLY318, GLY31Y, GLY408, GLY40Y, HIS458, HIS45Y, ILE358, ILE35Y, ILE478, LEU308, LEU30Y, LEU368, LEU36Y, LEU438, LEU43Y, LEU448, LEU44Y, LEU88, LYS288, LYS28Y, LYS328, LYS32Y, LYS488, LYS48Y, LYS498, LYS49Y, PHE468, PHE46Y, PRO238, PRO23Y, PRO258, PRO25Y, PRO278, PRO27Y, SER418, SER41Y, THR378, THR37Y, THR428, THR42Y
• Y-9: GLU1539, GLU53Y, HIS1509, HIS1529, HIS45Y, HIS52Y, ILE1519, ILE51Y, LEU30Y, LYS1489, LYS1499, LYS48Y, LYS49Y, PHE1469
• Y-a: ALA204a, ARG20Y, ASP206a, ASP207a, GLU209a, GLU21Y, GLU24Y, GLU253a, GLU53Y, ILE203a, LEU208a, MET201a, PRO23Y, PRO25Y, PRO27Y, THR205a, VAL234a
• Z-1: ALA104Z, ALA2041, ALA2381, ASP106Z, ASP107Z, ASP2071, CYS129Z, GLN139Z, GLN2391, GLU109Z, GLU2531, GLY133Z, GLY140Z, GLY2401, HIS145Z, HIS150Z, HIS152Z, HIS2451, HIS2501, HIS2521, ILE103Z, ILE135Z, ILE147Z, ILE151Z, ILE2031, ILE2471, ILE2511, LEU108Z, LEU130Z, LEU136Z, LEU143Z, LEU144Z, LEU2081, LEU2431, LEU2441, LYS132Z, LYS148Z, LYS149Z, LYS2481, LYS2491, MET101Z, MET2011, PHE146Z, PHE2461, SER141Z, SER2411, THR105Z, THR110Z, THR111Z, THR137Z, THR142Z, THR2371, THR2421, VAL102Z, VAL134Z, VAL2021
• Z-2: ALA138Z, ALA382, ARG120Z, ARG202, CYS126Z, CYS129Z, CYS262, CYS292, GLN139Z, GLN392, GLU121Z, GLU124Z, GLU212, GLU242, GLY119Z, GLY131Z, GLY140Z, GLY192, GLY312, GLY402, HIS145Z, HIS452, ILE135Z, ILE147Z, ILE352, ILE472, LEU130Z, LEU136Z, LEU143Z, LEU144Z, LEU302, LEU362, LEU432, LEU442, LYS128Z, LYS132Z, LYS148Z, LYS149Z, LYS282, LYS322, LYS482, LYS492, PHE146Z, PHE462, PRO113Z, PRO123Z, PRO125Z, PRO127Z, PRO232, PRO252, PRO272, SER141Z, SER412, THR137Z, THR142Z, THR372, THR422
• Z-3: GLU1533, HIS145Z, HIS1503, HIS1523, HIS152Z, ILE1513, ILE151Z, LEU130Z, LEU144Z, LYS132Z, LYS1483, LYS148Z, LYS1493, LYS149Z, PHE1463
• Z-4: ALA2044, ARG120Z, ASP2064, ASP2074, GLU121Z, GLU124Z, GLU2094, ILE2034, LEU2084, MET2014, PRO123Z, PRO125Z, PRO127Z, THR2054
• Z-7: ALA104Z, ARG2207, ASP106Z, ASP107Z, GLU109Z, GLU2227, GLU2247, ILE103Z, LEU108Z, MET101Z, PRO2237, PRO2257, PRO2277, THR105Z
• Z-8: GLU538, HIS150Z, HIS152Z, HIS458, HIS528, ILE151Z, ILE518, LEU308, LYS148Z, LYS149Z, LYS488, LYS498, PHE146Z
• Z-9: GLU1539, HIS1509, HIS150Z, HIS1529, HIS152Z, ILE1519, ILE151Z
• 1-2: GLU2531, HIS2501, HIS2521, HIS452, HIS522, ILE2511, ILE512, LEU302, LYS2481, LYS2491, LYS482, LYS492, PHE2461
• 1-3: GLU1533, GLU2531, HIS1503, HIS1523, HIS2501, HIS2521, ILE1513, ILE2511
• 1-5: GLU2531, GLU535, HIS2451, HIS2521, HIS505, HIS525, ILE2511, ILE515, LEU2301, LYS2321, LYS2481, LYS2491, LYS485, LYS495, PHE465
• 1-6: ALA1046, ARG2201, ASP1066, ASP1076, GLU1096, GLU1536, GLU2221, GLU2241, GLU2531, ILE1036, LEU1086, MET1016, PRO2231, PRO2251, PRO2271, THR1056
• 1-7: ALA2381, ALA2387, ARG2201, ARG2207, ASN2141, ASN2147, CYS2261, CYS2267, CYS2291, CYS2297, GLN2391, GLN2397, GLU2211, GLU2217, GLU2241, GLU2247, GLU2531, GLU2537, GLY2191, GLY2197, GLY2311, GLY2317, GLY2401, GLY2407, HIS2451, HIS2457, ILE2351, ILE2357, ILE2471, ILE2477, LEU2301, LEU2307, LEU2361, LEU2367, LEU2431, LEU2437, LEU2441, LEU2447, LYS2281, LYS2287, LYS2321, LYS2327, LYS2481, LYS2487, LYS2491, LYS2497, PHE2461, PHE2467, PRO2231, PRO2237, PRO2251, PRO2257, PRO2271, PRO2277, SER2411, SER2417, THR2371, THR2377, THR2421, THR2427
• 1-8: ALA2041, ARG208, ASP2061, ASP2071, GLU2091, GLU218, GLU228, GLU248, GLU2531, GLU538, ILE2031, ILE2511, LEU2081, MET2011, PRO238, PRO258, PRO278, THR2051
• 1-9: GLU1539, GLU2531
• 1-a: GLU2531, GLU253a
• 2-3: ALA1043, ALA1383, ALA42, ASP1073, ASP62, ASP72, CYS292, GLN1393, GLN392, GLU1533, GLU92, GLY1403, GLY312, GLY332, GLY402, HIS1453, HIS1503, HIS1523, HIS452, HIS502, HIS522, ILE1033, ILE1473, ILE1513, ILE32, ILE352, ILE472, ILE512, LEU1083, LEU1433, LEU1443, LEU302, LEU362, LEU432, LEU442, LEU82, LYS1483, LYS1493, LYS322, LYS482, LYS492, MET1013, MET12, PHE1463, PHE462, SER1413, SER412, THR102, THR1373, THR1423, THR372, THR422, THR52, VAL1023, VAL22, VAL342
• 2-4: ALA2044, ALA382, ALA42, ASP2064, ASP2074, ASP72, CYS2294, GLN2394, GLN392, GLU2094, GLY2334, GLY2404, GLY402, HIS2454, HIS2524, HIS452, HIS502, HIS522, ILE2034, ILE2354, ILE2474, ILE2514, ILE32, ILE472, ILE512, LEU2084, LEU2304, LEU2364, LEU2434, LEU2444, LEU432, LEU442, LEU82, LYS2324, LYS2484, LYS2494, LYS482, LYS492, MET12, MET2014, PHE2464, PHE462, SER2414, SER412, THR2054, THR2104, THR2374, THR2424, THR372, THR422, VAL2024, VAL22, VAL2344
• 2-5: GLU535, HIS502, HIS522, HIS525, ILE512, LEU305, LYS482, LYS485, LYS492, LYS495, PHE462
• 2-6: HIS1506, HIS1526, HIS502, HIS522, ILE1516, ILE512
• 2-a: ALA42, ARG220a, ASP62, ASP72, GLU222a, GLU224a, GLU253a, GLU92, HIS522, ILE32, ILE512, LEU82, MET12, PRO223a, PRO225a, PRO227a, THR52
• 3-4: ALA1043, ALA2044, ALA2384, ASP1063, ASP1073, ASP2074, CYS1293, GLN1393, GLN2394, GLU1093, GLU1533, GLY1313, GLY1333, GLY1403, GLY2404, HIS1453, HIS1523, HIS2454, HIS2504, HIS2524, ILE1033, ILE1353, ILE1473, ILE1513, ILE2034, ILE2474, ILE2514, LEU1083, LEU1303, LEU1363, LEU1433, LEU1443, LEU2084, LEU2434, LEU2444, LYS1323, LYS1483, LYS1493, LYS2484, LYS2494, MET1013, MET2014, PHE1463, PHE2464, SER1413, SER2414, THR1053, THR1103, THR1373, THR1423, THR2374, THR2424, VAL1023, VAL1343, VAL2024
• 3-5: ALA1043, ARG205, ASP1063, ASP1073, GLU1093, GLU1533, GLU215, GLU225, GLU245, GLU535, ILE1033, ILE1513, LEU1083, MET1013, PRO235, PRO255, PRO275, THR1053
• 3-7: GLU1533, GLU2537
• 3-8: GLU1533, GLU538, HIS1453, HIS1523, HIS508, HIS528, ILE1513, ILE518, LEU1303, LEU1443, LYS1483, LYS1493, LYS488, LYS498, PHE468
• 3-9: ALA1049, ARG1203, ASP1069, ASP1079, GLU1099, GLU1213, GLU1223, GLU1243, GLU1533, GLU1539, ILE1039, LEU1089, MET1019, PRO1233, PRO1253, PRO1273, THR1059
• 3-a: ALA1383, ALA238a, ARG1203, ARG220a, ASN1143, ASN214a, CYS1263, CYS1293, CYS226a, CYS229a, GLN1393, GLN239a, GLU1213, GLU1243, GLU1533, GLU221a, GLU224a, GLU253a, GLY1193, GLY1313, GLY1403, GLY219a, GLY231a, GLY240a, HIS1453, HIS245a, ILE1353, ILE1473, ILE235a, ILE247a, LEU1303, LEU1363, LEU1433, LEU1443, LEU230a, LEU236a, LEU243a, LEU244a, LYS1283, LYS1323, LYS1483, LYS1493, LYS228a, LYS232a, LYS248a, LYS249a, PHE1463, PHE246a, PRO1233, PRO1253, PRO1273, PRO223a, PRO225a, PRO227a, SER1413, SER241a, THR1373, THR1423, THR237a, THR242a
• 4-5: ALA2384, ALA385, ARG205, ARG2204, ASN145, ASN2144, CYS2264, CYS2294, CYS265, CYS295, GLN2394, GLN395, GLU215, GLU2214, GLU2244, GLU245, GLU535, GLY195, GLY2194, GLY2314, GLY2404, GLY315, GLY405, HIS2454, HIS2524, HIS455, ILE2354, ILE2474, ILE2514, ILE355, ILE475, LEU2304, LEU2364, LEU2434, LEU2444, LEU305, LEU365, LEU435, LEU445, LYS2284, LYS2324, LYS2484, LYS2494, LYS285, LYS325, LYS485, LYS495, PHE2464, PHE465, PRO135, PRO2134, PRO2234, PRO2254, PRO2274, PRO235, PRO255, PRO275, SER2414, SER415, THR2374, THR2424, THR375, THR425
• 4-6: GLU1536, HIS1506, HIS1526, HIS2454, HIS2524, ILE1516, ILE2514, LEU2304, LEU2444, LYS1486, LYS1496, LYS2324, LYS2484, LYS2494, PHE1466
• 4-7: ALA2047, ARG2204, ASP2067, ASP2077, GLU2097, GLU2214, GLU2224, GLU2244, ILE2037, LEU2087, MET2017, PRO2234, PRO2254, PRO2274, THR2057
• 4-8: GLU538, HIS2504, HIS2524, HIS508, HIS528, ILE2514, ILE518
• 4-a: GLU253a, HIS245a, HIS2504, HIS2524, HIS252a, ILE2514, LEU230a, LYS232a, LYS2484, LYS248a, LYS2494, LYS249a, PHE2464
• 5-6: ALA1046, ALA1386, ALA45, ASP1076, ASP65, ASP75, CYS295, GLN1396, GLN395, GLU1536, GLU535, GLU95, GLY1406, GLY315, GLY335, GLY405, HIS1456, HIS1506, HIS1526, HIS455, HIS525, ILE1036, ILE1476, ILE1516, ILE35, ILE355, ILE475, ILE515, LEU1086, LEU1436, LEU1446, LEU305, LEU365, LEU435, LEU445, LEU85, LYS1486, LYS1496, LYS325, LYS485, LYS495, MET1016, MET15, PHE1466, PHE465, SER1416, SER415, THR105, THR1376, THR1426, THR375, THR425, THR55, VAL1026, VAL25, VAL345
• 5-7: ALA2047, ALA385, ALA45, ASP2067, ASP2077, ASP75, CYS2297, GLN2397, GLN395, GLU2097, GLU2537, GLU535, GLY2337, GLY2407, GLY405, HIS2457, HIS2507, HIS2527, HIS455, HIS505, HIS525, ILE2037, ILE2357, ILE2477, ILE2517, ILE35, ILE475, ILE515, LEU2087, LEU2307, LEU2367, LEU2437, LEU2447, LEU435, LEU445, LEU85, LYS2327, LYS2487, LYS2497, LYS485, LYS495, MET15, MET2017, PHE2467, PHE465, SER2417, SER415, THR2057, THR2107, THR2377, THR2427, THR375, THR425, VAL2027, VAL2347, VAL25
• 5-8: GLU535, GLU538
• 5-9: ALA45, ARG1209, ASP65, ASP75, GLU1219, GLU1249, GLU1539, GLU535, GLU95, ILE35, LEU85, MET15, PRO1239, PRO1259, PRO1279, THR55
• 5-a: GLU253a, GLU535
• 6-7: ALA1046, ALA2047, ALA2387, ASP1066, ASP1076, ASP2077, CYS1296, GLN1396, GLN2397, GLU1096, GLU1536, GLU2537, GLY1316, GLY1336, GLY1406, GLY2407, HIS1456, HIS1526, HIS2457, HIS2507, HIS2527, ILE1036, ILE1356, ILE1476, ILE1516, ILE2037, ILE2477, ILE2517, LEU1086, LEU1306, LEU1366, LEU1436, LEU1446, LEU2087, LEU2437, LEU2447, LYS1326, LYS1486, LYS1496, LYS2487, LYS2497, MET1016, MET2017, PHE1466, PHE2467, SER1416, SER2417, THR1056, THR1106, THR1376, THR1426, THR2377, THR2427, VAL1026, VAL1346, VAL2027
• 6-8: ALA48, ARG1206, ASP68, ASP78, GLU1216, GLU1226, GLU1246, GLU1536, GLU538, GLU98, ILE38, LEU88, MET18, PRO1236, PRO1256, PRO1276, THR58
• 6-9: ALA1386, ALA1389, ARG1206, ARG1209, ASN1146, ASN1149, CYS1266, CYS1269, CYS1296, CYS1299, GLN1396, GLN1399, GLU1216, GLU1219, GLU1246, GLU1249, GLU1536, GLU1539, GLY1196, GLY1199, GLY1316, GLY1319, GLY1406, GLY1409, HIS1456, HIS1459, HIS1529, ILE1356, ILE1359, ILE1476, LEU1306, LEU1309, LEU1366, LEU1369, LEU1436, LEU1439, LEU1446, LEU1449, LYS1286, LYS1289, LYS1326, LYS1329, LYS1486, LYS1489, LYS1496, LYS1499, PHE1466, PHE1469, PRO1136, PRO1236, PRO1239, PRO1256, PRO1259, PRO1276, PRO1279, SER1416, SER1419, THR1376, THR1379, THR1426, THR1429
• 6-a: GLU1536, GLU253a, HIS1456, HIS1526, HIS250a, HIS252a, ILE1516, ILE251a, LEU1306, LYS1486, LYS1496, LYS248a, LYS249a, PHE246a
• 7-8: GLU2537, GLU538, ILE518
• 7-9: GLU1539, GLU2537, HIS1459, HIS1529, HIS2507, HIS2527, ILE1519, ILE2517, LEU1309, LYS1489, LYS1499, LYS2487, LYS2497, PHE2467
• 7-a: GLU2537, GLU253a, HIS2507, HIS250a, HIS2527, HIS252a, ILE2517, ILE251a
• 8-9: ALA1049, ALA1389, ALA48, ASP1079, ASP68, ASP78, CYS298, GLN1399, GLN398, GLU1539, GLU538, GLU98, GLY1409, GLY178, GLY318, GLY338, GLY408, HIS1459, HIS1509, HIS1529, HIS458, HIS528, ILE1039, ILE1479, ILE1519, ILE358, ILE38, ILE478, ILE518, LEU1089, LEU1439, LEU1449, LEU308, LEU368, LEU438, LEU448, LEU88, LYS1489, LYS1499, LYS328, LYS488, LYS498, MET1019, MET18, PHE1469, PHE468, SER1419, SER418, THR108, THR118, THR1379, THR1429, THR378, THR428, THR58, VAL1029, VAL28, VAL348
• 8-a: ALA204a, ALA388, ALA48, ASP206a, ASP207a, ASP78, CYS229a, GLN239a, GLN398, GLU209a, GLU253a, GLU538, GLY233a, GLY240a, GLY408, HIS245a, HIS250a, HIS252a, HIS458, HIS508, HIS528, ILE203a, ILE235a, ILE247a, ILE251a, ILE38, ILE478, ILE518, LEU208a, LEU230a, LEU236a, LEU243a, LEU244a, LEU438, LEU448, LEU88, LYS232a, LYS248a, LYS249a, LYS488, LYS498, MET201a, PHE246a, PHE468, SER241a, SER418, THR205a, THR210a, THR211a, THR237a, THR242a, THR378, THR428, VAL202a, VAL234a, VAL28
• 9-a: ALA1049, ALA204a, ALA238a, ASP1069, ASP1079, ASP207a, CYS1299, GLN1399, GLN239a, GLU1099, GLU1539, GLU253a, GLY1339, GLY1409, GLY240a, HIS1459, HIS1509, HIS1529, HIS245a, HIS250a, HIS252a, ILE1039, ILE1359, ILE1479, ILE1519, ILE203a, ILE247a, ILE251a, LEU1089, LEU1309, LEU1369, LEU1439, LEU1449, LEU208a, LEU243a, LEU244a, LYS1329, LYS1489, LYS1499, LYS248a, LYS249a, MET1019, MET201a, PHE1469, PHE246a, SER1419, SER241a, THR1059, THR1109, THR1379, THR1429, THR237a, THR242a, VAL1029, VAL1349, VAL202a
• b-c: ALA104c, ALA138c, ALA4b, ASP107c, ASP6b, ASP7b, CYS29b, GLN139c, GLN39b, GLU153c, GLU53b, GLU9b, GLY140c, GLY31b, GLY33b, GLY40b, HIS145c, HIS150c, HIS152c, HIS45b, HIS52b, ILE103c, ILE147c, ILE151c, ILE35b, ILE3b, ILE47b, ILE51b, LEU108c, LEU143c, LEU144c, LEU30b, LEU36b, LEU43b, LEU44b, LEU8b, LYS148c, LYS149c, LYS32b, LYS48b, LYS49b, MET101c, MET1b, PHE146c, PHE46b, SER141c, SER41b, THR10b, THR137c, THR142c, THR37b, THR42b, THR5b, VAL102c, VAL2b, VAL34b
• b-d: ALA204d, ALA38b, ALA4b, ASP206d, ASP207d, ASP7b, CYS229d, GLN239d, GLN39b, GLU209d, GLU253d, GLU53b, GLY231d, GLY233d, GLY240d, GLY40b, HIS245d, HIS252d, HIS45b, HIS50b, HIS52b, ILE203d, ILE235d, ILE247d, ILE251d, ILE3b, ILE47b, ILE51b, LEU208d, LEU230d, LEU236d, LEU243d, LEU244d, LEU43b, LEU44b, LEU8b, LYS232d, LYS248d, LYS249d, LYS48b, LYS49b, MET1b, MET201d, PHE246d, PHE46b, SER241d, SER41b, THR205d, THR210d, THR237d, THR242d, THR37b, THR42b, VAL202d, VAL234d, VAL2b
• b-e: ALA4b, ARG20e, ASP6b, ASP7b, GLU22e, GLU24e, GLU53b, GLU53e, GLU9b, ILE3b, LEU8b, MET1b, PRO23e, PRO25e, PRO27e, THR5b
• b-g: GLU253g, GLU53b
• b-h: GLU53b, GLU53h, HIS50b, HIS50h, HIS52b, HIS52h, ILE51b, ILE51h
• b-i: GLU153i, GLU53b
• b-j: GLU253j, GLU53b, HIS245j, HIS252j, HIS50b, HIS52b, ILE251j, ILE51b, LEU230j, LEU244j, LYS248j, LYS249j, LYS48b, LYS49b, PHE46b
• b-k: ALA38b, ALA38k, ARG20b, ARG20k, ASN14b, CYS26b, CYS26k, CYS29b, CYS29k, GLN39b, GLN39k, GLU21b, GLU21k, GLU24b, GLU24k, GLU53b, GLU53k, GLY19b, GLY19k, GLY31b, GLY31k, GLY40b, GLY40k, HIS45b, HIS45k, ILE35b, ILE35k, ILE47k, LEU30b, LEU30k, LEU36b, LEU36k, LEU43b, LEU43k, LEU44b, LEU44k, LYS28b, LYS28k, LYS32b, LYS32k, LYS48b, LYS48k, LYS49b, LYS49k, PHE46b, PHE46k, PRO23b, PRO23k, PRO25b, PRO25k, PRO27b, PRO27k, SER41b, SER41k, THR37b, THR37k, THR42b, THR42k
• b-l: GLU53b, HIS150l, HIS152l, HIS52b, ILE151l, ILE51b, LEU30b, LYS149l, LYS48b, LYS49b, PHE146l
• b-m: ALA204m, ARG20b, ASP206m, ASP207m, GLU209m, GLU24b, GLU253m, GLU53b, ILE203m, ILE251m, LEU208m, MET201m, PRO23b, PRO25b, PRO27b, THR205m
• c-d: ALA104c, ALA204d, ALA238d, ASP106c, ASP107c, ASP207d, CYS129c, GLN139c, GLN239d, GLU109c, GLU153c, GLU253d, GLY133c, GLY140c, GLY240d, HIS145c, HIS152c, HIS245d, HIS250d, HIS252d, ILE103c, ILE135c, ILE147c, ILE151c, ILE203d, ILE247d, ILE251d, LEU108c, LEU130c, LEU136c, LEU143c, LEU144c, LEU208d, LEU243d, LEU244d, LYS132c, LYS148c, LYS149c, LYS248d, LYS249d, MET101c, MET201d, PHE146c, PHE246d, SER141c, SER241d, THR105c, THR110c, THR137c, THR142c, THR237d, THR242d, VAL102c, VAL134c, VAL202d
• c-e: ALA138c, ALA38e, ARG120c, ARG20e, ASN114c, ASN14e, CYS126c, CYS129c, CYS26e, CYS29e, GLN139c, GLN39e, GLU121c, GLU124c, GLU153c, GLU21e, GLU24e, GLU53e, GLY119c, GLY131c, GLY140c, GLY19e, GLY31e, GLY40e, HIS145c, HIS45e, HIS52e, ILE135c, ILE147c, ILE35e, ILE47e, LEU130c, LEU136c, LEU143c, LEU144c, LEU30e, LEU36e, LEU43e, LEU44e, LYS128c, LYS132c, LYS148c, LYS149c, LYS28e, LYS32e, LYS48e, LYS49e, PHE146c, PHE46e, PRO113c, PRO123c, PRO125c, PRO127c, PRO13e, PRO23e, PRO25e, PRO27e, SER141c, SER41e, THR137c, THR142c, THR37e, THR42e
• c-f: GLU153c, GLU153f, HIS145c, HIS150f, HIS152c, HIS152f, ILE151c, ILE151f, LEU130c, LEU144c, LYS148c, LYS148f, LYS149c, LYS149f, PHE146f
• c-g: ALA204g, ARG120c, ASP206g, ASP207g, GLU121c, GLU124c, GLU153c, GLU209g, GLU253g, ILE203g, ILE251g, LEU208g, MET201g, PRO123c, PRO125c, PRO127c, THR205g
• c-h: GLU153c, GLU53h
• c-j: ALA104c, ARG220j, ASP106c, ASP107c, GLU109c, GLU221j, GLU222j, GLU224j, ILE103c, LEU108c, MET101c, PRO223j, PRO225j, PRO227j, THR105c
• c-k: GLU153c, GLU53k, HIS150c, HIS152c, HIS45k, HIS52k, ILE151c, ILE51k, LEU30k, LYS148c, LYS149c, LYS48k, LYS49k, PHE146c
• c-l: GLU153c, HIS150c, HIS150l, HIS152c, HIS152l, ILE151c, ILE151l
• c-m: GLU153c, GLU253m
• d-e: GLU253d, GLU53e, HIS250d, HIS252d, HIS45e, HIS52e, ILE251d, ILE51e, LEU30e, LEU44e, LYS249d, LYS32e, LYS48e, LYS49e, PHE246d
• d-f: GLU153f, GLU253d, HIS150f, HIS152f, HIS250d, HIS252d, ILE151f, ILE251d
• d-g: GLU253d, GLU253g
• d-h: GLU253d, GLU53h, HIS245d, HIS252d, HIS50h, HIS52h, ILE251d, ILE51h, LEU230d, LEU244d, LYS232d, LYS248d, LYS249d, LYS48h, LYS49h, PHE46h
• d-i: ALA104i, ARG220d, ASP106i, ASP107i, GLU109i, GLU153i, GLU222d, GLU224d, GLU253d, ILE103i, LEU108i, MET101i, PRO223d, PRO225d, PRO227d, THR105i
• d-j: ALA238d, ALA238j, ARG220d, ARG220j, ASN214j, CYS226d, CYS226j, CYS229d, CYS229j, GLN239d, GLN239j, GLU221d, GLU221j, GLU224d, GLU224j, GLU253d, GLU253j, GLY219d, GLY219j, GLY231d, GLY231j, GLY240d, GLY240j, HIS245d, HIS245j, ILE235d, ILE235j, ILE247d, ILE247j, LEU230d, LEU230j, LEU236d, LEU236j, LEU243d, LEU243j, LEU244d, LEU244j, LYS228d, LYS228j, LYS232d, LYS232j, LYS248d, LYS248j, LYS249d, LYS249j, PHE246d, PHE246j, PRO223d, PRO223j, PRO225d, PRO225j, PRO227d, PRO227j, SER241d, SER241j, THR237d, THR237j, THR242d, THR242j
• d-k: ALA204d, ARG20k, ASP206d, ASP207d, GLU209d, GLU21k, GLU22k, GLU24k, GLU253d, GLU53k, ILE203d, ILE251d, LEU208d, MET201d, PRO23k, PRO25k, PRO27k, THR205d
• d-l: GLU253d, HIS152l
• d-m: GLU253d, GLU253m
• e-f: ALA104f, ALA138f, ALA4e, ASP107f, ASP6e, ASP7e, CYS29e, GLN139f, GLN39e, GLU153f, GLU53e, GLU9e, GLY140f, GLY31e, GLY33e, GLY40e, HIS145f, HIS150f, HIS152f, HIS45e, HIS52e, ILE103f, ILE147f, ILE151f, ILE35e, ILE3e, ILE47e, ILE51e, LEU108f, LEU143f, LEU144f, LEU30e, LEU36e, LEU43e, LEU44e, LEU8e, LYS148f, LYS149f, LYS32e, LYS48e, LYS49e, MET101f, MET1e, PHE146f, PHE46e, SER141f, SER41e, THR10e, THR137f, THR142f, THR37e, THR42e, THR5e, VAL102f, VAL2e, VAL34e
• e-g: ALA204g, ALA38e, ALA4e, ASP206g, ASP207g, ASP7e, CYS229g, GLN239g, GLN39e, GLU209g, GLU253g, GLU53e, GLY233g, GLY240g, GLY40e, HIS245g, HIS252g, HIS45e, HIS50e, HIS52e, ILE203g, ILE235g, ILE247g, ILE251g, ILE3e, ILE47e, ILE51e, LEU208g, LEU230g, LEU236g, LEU243g, LEU244g, LEU43e, LEU44e, LEU8e, LYS232g, LYS248g, LYS249g, LYS48e, LYS49e, MET201g, PHE246g, PHE46e, SER241g, SER41e, THR205g, THR210g, THR237g, THR242g, THR37e, THR42e, VAL202g, VAL234g, VAL2e
• e-h: GLU53e, GLU53h, HIS45h, HIS50e, HIS52e, HIS52h, ILE51e, ILE51h, LEU30h, LYS48e, LYS48h, LYS49e, LYS49h, PHE46e
• e-i: GLU153i, GLU53e, HIS150i, HIS152i, HIS50e, HIS52e, ILE151i, ILE51e
• e-j: GLU253j, GLU53e
• e-k: GLU53e, GLU53k
• e-m: ALA4e, ARG220m, ASP6e, ASP7e, GLU221m, GLU224m, GLU253m, GLU53e, GLU9e, ILE3e, LEU8e, MET1e, PRO223m, PRO225m, PRO227m, THR5e
• f-g: ALA104f, ALA238g, ASP106f, ASP107f, ASP207g, CYS129f, GLN139f, GLN239g, GLU109f, GLU153f, GLU253g, GLY133f, GLY140f, GLY240g, HIS145f, HIS152f, HIS245g, HIS250g, HIS252g, ILE103f, ILE135f, ILE147f, ILE151f, ILE203g, ILE247g, ILE251g, LEU108f, LEU130f, LEU136f, LEU143f, LEU144f, LEU208g, LEU243g, LEU244g, LYS132f, LYS148f, LYS149f, LYS248g, LYS249g, MET101f, PHE146f, PHE246g, SER141f, SER241g, THR105f, THR110f, THR137f, THR142f, THR237g, THR242g, VAL102f, VAL134f, VAL202g
• f-h: ALA104f, ARG20h, ASP106f, ASP107f, GLU109f, GLU153f, GLU21h, GLU22h, GLU24h, GLU53h, ILE103f, ILE151f, LEU108f, MET101f, PRO23h, PRO25h, PRO27h, THR105f
• f-i: GLU153f, GLU153i
• f-k: GLU153f, GLU53k, HIS145f, HIS152f, HIS50k, HIS52k, ILE151f, ILE51k, LEU130f, LEU144f, LYS148f, LYS149f, LYS48k, LYS49k, PHE46k
• f-l: ALA104l, ARG120f, ASP106l, ASP107l, GLU109l, GLU121f, GLU124f, ILE103l, LEU108l, MET101l, PRO123f, PRO125f, PRO127f, THR105l
• f-m: ALA138f, ALA238m, ARG120f, ARG220m, ASN114f, CYS126f, CYS129f, CYS226m, CYS229m, GLN139f, GLN239m, GLU121f, GLU124f, GLU153f, GLU221m, GLU224m, GLU253m, GLY119f, GLY131f, GLY140f, GLY219m, GLY231m, GLY240m, HIS145f, HIS245m, HIS252m, ILE135f, ILE147f, ILE235m, LEU130f, LEU136f, LEU143f, LEU144f, LEU208m, LEU230m, LEU236m, LEU243m, LEU244m, LYS128f, LYS132f, LYS148f, LYS149f, LYS228m, LYS232m, LYS248m, LYS249m, PHE146f, PHE246m, PRO113f, PRO123f, PRO125f, PRO127f, PRO213m, PRO223m, PRO225m, PRO227m, SER141f, SER241m, THR137f, THR142f, THR237m, THR242m
• g-h: ALA238g, ALA38h, ARG20h, ARG220g, ASN214g, CYS226g, CYS229g, CYS26h, CYS29h, GLN239g, GLN39h, GLU21h, GLU221g, GLU224g, GLU24h, GLU253g, GLU53h, GLY19h, GLY219g, GLY231g, GLY240g, GLY31h, GLY40h, HIS245g, HIS45h, ILE235g, ILE247g, ILE35h, ILE47h, LEU230g, LEU236g, LEU243g, LEU244g, LEU30h, LEU36h, LEU43h, LEU44h, LYS228g, LYS232g, LYS248g, LYS249g, LYS28h, LYS32h, LYS48h, LYS49h, PHE246g, PHE46h, PRO13h, PRO213g, PRO223g, PRO225g, PRO227g, PRO23h, PRO25h, PRO27h, SER241g, SER41h, THR237g, THR242g, THR37h, THR42h
• g-i: GLU153i, GLU253g, HIS150i, HIS152i, HIS245g, HIS252g, ILE151i, ILE251g, LEU230g, LYS148i, LYS149i, LYS248g, LYS249g, PHE146i
• g-j: ALA204j, ARG220g, ASP206j, ASP207j, GLU209j, GLU221g, GLU224g, ILE203j, LEU208j, MET201j, PRO223g, PRO225g, PRO227g, THR205j
• g-k: GLU253g, GLU53k, HIS250g, HIS252g, HIS50k, HIS52k, ILE251g, ILE51k
• g-l: GLU253g, HIS152l, ILE151l
• g-m: GLU253g, GLU253m, HIS245m, HIS250g, HIS252g, HIS252m, ILE251g, ILE251m, LEU230m, LYS232m, LYS248g, LYS248m, LYS249g, LYS249m, PHE246g
• h-i: ALA104i, ALA138i, ALA4h, ASP107i, ASP6h, ASP7h, CYS29h, GLN139i, GLN39h, GLU153i, GLU53h, GLU9h, GLY140i, GLY31h, GLY33h, GLY40h, HIS145i, HIS150i, HIS152i, HIS45h, HIS52h, ILE103i, ILE147i, ILE151i, ILE35h, ILE3h, ILE47h, ILE51h, LEU108i, LEU143i, LEU144i, LEU30h, LEU36h, LEU43h, LEU44h, LEU8h, LYS148i, LYS149i, LYS32h, LYS48h, LYS49h, MET101i, MET1h, PHE146i, PHE46h, SER141i, SER41h, THR10h, THR137i, THR142i, THR37h, THR42h, THR5h, VAL102i, VAL2h, VAL34h
• h-j: ALA204j, ALA38h, ALA4h, ASP206j, ASP207j, ASP7h, CYS229j, GLN239j, GLN39h, GLU209j, GLU253j, GLU53h, GLY231j, GLY233j, GLY240j, GLY40h, HIS245j, HIS252j, HIS45h, HIS50h, HIS52h, ILE203j, ILE235j, ILE247j, ILE251j, ILE3h, ILE47h, ILE51h, LEU208j, LEU230j, LEU236j, LEU243j, LEU244j, LEU43h, LEU44h, LEU8h, LYS232j, LYS248j, LYS249j, LYS48h, LYS49h, MET1h, MET201j, PHE246j, PHE46h, SER241j, SER41h, THR205j, THR210j, THR237j, THR242j, THR37h, THR42h, VAL202j, VAL234j, VAL2h
• h-k: GLU53h, GLU53k
• h-l: ALA4h, ARG120l, ASP6h, ASP7h, GLU121l, GLU122l, GLU124l, GLU9h, ILE3h, LEU8h, MET1h, PRO123l, PRO125l, PRO127l, THR5h
• h-m: GLU253m, GLU53h
• i-j: ALA104i, ALA204j, ALA238j, ASP106i, ASP107i, ASP207j, CYS129i, GLN139i, GLN239j, GLU109i, GLU153i, GLU253j, GLY117i, GLY131i, GLY133i, GLY140i, GLY240j, HIS145i, HIS152i, HIS245j, HIS250j, HIS252j, ILE103i, ILE135i, ILE147i, ILE151i, ILE203j, ILE247j, ILE251j, LEU108i, LEU130i, LEU136i, LEU143i, LEU144i, LEU208j, LEU243j, LEU244j, LYS132i, LYS148i, LYS149i, LYS248j, LYS249j, MET101i, MET201j, PHE146i, PHE246j, SER141i, SER241j, THR105i, THR110i, THR111i, THR137i, THR142i, THR237j, THR242j, VAL102i, VAL134i, VAL202j
• i-k: ALA4k, ARG120i, ASP6k, ASP7k, GLU122i, GLU124i, GLU153i, GLU53k, GLU9k, ILE3k, LEU8k, MET1k, PRO123i, PRO125i, PRO127i, THR5k
• i-l: ALA138i, ALA138l, ARG120i, ARG120l, ASN114l, CYS126i, CYS126l, CYS129i, CYS129l, GLN139i, GLN139l, GLU121i, GLU121l, GLU124i, GLU124l, GLY119i, GLY119l, GLY131i, GLY131l, GLY133i, GLY140i, GLY140l, HIS145i, HIS145l, ILE135i, ILE135l, ILE147l, LEU130i, LEU130l, LEU136i, LEU136l, LEU143i, LEU143l, LEU144i, LEU144l, LYS128i, LYS128l, LYS132i, LYS132l, LYS148i, LYS148l, LYS149i, LYS149l, PHE146i, PHE146l, PRO113i, PRO123i, PRO123l, PRO125i, PRO125l, PRO127i, PRO127l, SER141i, SER141l, THR137i, THR137l, THR142i, THR142l
• i-m: GLU153i, GLU253m, HIS152i, HIS250m, HIS252m, ILE151i, ILE251m, LEU130i, LYS132i, LYS148i, LYS149i, LYS248m, LYS249m, PHE246m
• j-l: GLU253j, HIS145l, HIS152l, HIS250j, HIS252j, ILE251j, LEU130l, LEU144l, LYS148l, LYS149l, LYS248j, LYS249j, PHE246j
• j-m: GLU253j, GLU253m, HIS250j, HIS250m, HIS252j, HIS252m, ILE251j, ILE251m
• k-l: ALA104l, ALA138l, ALA4k, ASP107l, ASP6k, ASP7k, CYS29k, GLN139l, GLN39k, GLU53k, GLU9k, GLY140l, GLY31k, GLY33k, GLY40k, HIS145l, HIS150l, HIS152l, HIS45k, HIS52k, ILE103l, ILE147l, ILE151l, ILE35k, ILE3k, ILE47k, ILE51k, LEU108l, LEU143l, LEU144l, LEU30k, LEU36k, LEU43k, LEU44k, LEU8k, LYS148l, LYS149l, LYS32k, LYS48k, LYS49k, MET101l, MET1k, PHE146l, PHE46k, SER141l, SER41k, THR10k, THR137l, THR142l, THR37k, THR42k, THR5k, VAL102l, VAL2k, VAL34k
• k-m: ALA204m, ALA38k, ALA4k, ASP206m, ASP207m, ASP7k, CYS229m, GLN239m, GLN39k, GLU209m, GLU253m, GLU53k, GLY231m, GLY233m, GLY240m, GLY40k, HIS245m, HIS252m, HIS45k, HIS50k, HIS52k, ILE203m, ILE235m, ILE247m, ILE251m, ILE3k, ILE47k, ILE51k, LEU208m, LEU230m, LEU236m, LEU243m, LEU244m, LEU43k, LEU44k, LEU8k, LYS232m, LYS248m, LYS249m, LYS48k, LYS49k, MET1k, MET201m, PHE246m, PHE46k, SER241m, SER41k, THR205m, THR210m, THR211m, THR237m, THR242m, THR37k, THR42k, VAL202m, VAL234m, VAL2k
• l-m: ALA104l, ALA204m, ALA238m, ASP106l, ASP107l, ASP207m, CYS129l, GLN139l, GLN239m, GLU109l, GLU253m, GLY133l, GLY140l, GLY240m, HIS145l, HIS150l, HIS152l, HIS245m, HIS250m, HIS252m, ILE103l, ILE135l, ILE147l, ILE151l, ILE203m, ILE247m, ILE251m, LEU108l, LEU130l, LEU136l, LEU143l, LEU144l, LEU208m, LEU243m, LEU244m, LYS132l, LYS148l, LYS149l, LYS248m, LYS249m, MET101l, MET201m, PHE146l, PHE246m, SER141l, SER241m, THR105l, THR110l, THR137l, THR142l, THR237m, THR242m, VAL102l, VAL134l, VAL202m