3L9J

selection of a novel highly specific tnfalpha antagonist: insight from the crystal structure of the antagonist- tnfalpha complex

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: C-T
  • Int. Res.: 75
  • Norm. En. per Res.: -6.0563
• Hub Node: C(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-T	-69.4761	-119.0321	-265.715	-454.2232	75	10	1	8924	8	23	16

Interface residues

• C-T: ALA109T, ALA111T, ALA132C, ALA145T, ALA22T, ARG103T, ARG117C, ARG120C, ARG130C, ARG138T, ARG167C, ARG169C, ASN115C, ASN137T, ASN148C, ASN151C, ASP125C, ASP140T, ASP143T, ASP145C, CYS101T, CYS168C, CYS69T, GLN143C, GLN21T, GLN25T, GLN67T, GLN88C, GLU104T, GLU107T, GLU110T, GLU23T, GLY108T, GLY128C, GLY24T, GLY66T, GLY68T, HIS73T, ILE131C, LEU142T, LEU63T, LEU75T, LEU76T, LYS112T, LYS116C, LYS134C, LYS65T, MET126C, PHE122C, PHE144T, PHE64T, PRO100T, PRO106T, PRO113T, PRO139T, PRO144C, PRO146C, PRO20T, PRO70T, SER119C, SER147C, SER71T, THR105T, THR127C, THR129C, THR72T, TRP114T, TRP118C, TRP123C, TRP149C, TYR121C, TYR133C, TYR141T, VAL124C, VAL74T