3KYS

crystal structure of human yap and tead complex

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 142
  • Norm. En. per Res.: -4.4532
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-98.7023	-48.1692	-485.479	-632.3505	142	23	12	18993	5	38	39
A-C	-103.0003	34.1008	-166.391	-235.2905	70	11	0	5777	2	33	23
C-D	-83.6875	-52.8366	-440.355	-576.8791	136	37	12	18103	5	38	35

Interface residues

• A-B: ALA389A, ALA401A, ALA50B, ALA67B, ALA71B, ALA78B, ARG245A, ARG337A, ARG340A, ARG379A, ARG407A, ARG58B, ARG87B, ARG89B, ASN339A, ASN349A, ASN364A, ASN369A, ASN396A, ASN70B, ASP243A, ASP249A, ASP60B, ASP64B, ASP93B, CYS307A, CYS312A, CYS344A, CYS390A, GLN246A, GLN317A, GLN402A, GLN53B, GLN82B, GLU100B, GLU240A, GLU320A, GLU323A, GLU325A, GLU345A, GLU368A, GLU393A, GLU62B, GLU66B, GLY292A, GLY315A, GLY400A, GLY51B, GLY59B, HIS352A, HIS356A, HIS399A, HIS403A, HIS404A, HIS52B, HIS56B, ILE244A, ILE247A, ILE338A, ILE348A, ILE351A, ILE405A, ILE54B, LEU272A, LEU354A, LEU357A, LEU367A, LEU408A, LEU65B, LEU68B, LEU88B, LEU91B, LYS250A, LYS274A, LYS310A, LYS316A, LYS321A, LYS353A, LYS355A, LYS90B, LYS97B, MET343A, MET347A, MET362A, MET363A, MET73B, MET86B, PHE251A, PHE275A, PHE290A, PHE314A, PHE350A, PHE370A, PHE392A, PHE69B, PHE95B, PHE96B, PRO252A, PRO342A, PRO358A, PRO81B, PRO85B, PRO92B, PRO98B, PRO99B, SER241A, SER308A, SER313A, SER341A, SER365A, SER395A, SER397A, SER61B, SER94B, THR304A, THR306A, THR309A, THR324A, THR371A, THR63B, THR83B, TRP276A, TYR248A, TYR326A, TYR346A, TYR361A, TYR406A, VAL242A, VAL273A, VAL293A, VAL311A, VAL318A, VAL319A, VAL322A, VAL366A, VAL391A, VAL394A, VAL55B, VAL57B, VAL72B, VAL80B, VAL84B
• A-C: ALA208A, ALA208C, ALA230C, ALA277A, ALA277C, ALA401A, ALA401C, ARG214A, ARG214C, ASN220A, ASN220C, ASN280A, ASN280C, ASN282A, ASN282C, ASP215A, ASP215C, ASP217A, ASP217C, ASP278A, ASP278C, CYS281A, CYS281C, GLN212A, GLN212C, GLN213A, GLN213C, GLN402A, GLN402C, GLU211A, GLU211C, GLU398A, GLU398C, GLY400A, GLY400C, HIS222A, HIS222C, HIS226A, HIS226C, HIS229A, HIS229C, HIS399A, HIS399C, LEU210A, LEU210C, LEU223A, LEU223C, LEU279A, LEU279C, LYS221A, LYS221C, PHE209A, PHE209C, PHE224A, PHE224C, PRO216A, PRO216C, SER207A, SER218A, SER218C, SER395A, SER395C, SER397A, SER397C, TRP276A, TRP276C, TYR219A, TYR219C, VAL225A, VAL225C
• C-D: ALA389C, ALA401C, ALA67D, ALA71D, ALA78D, ARG245C, ARG340C, ARG379C, ARG407C, ARG58D, ARG87D, ARG89D, ASN349C, ASN364C, ASN369C, ASN396C, ASN70D, ASN79D, ASP243C, ASP249C, ASP60D, ASP64D, ASP93D, CYS307C, CYS312C, CYS344C, CYS390C, GLN246C, GLN317C, GLN402C, GLN53D, GLN82D, GLU100D, GLU240C, GLU320C, GLU323C, GLU345C, GLU359C, GLU368C, GLU393C, GLU62D, GLU66D, GLY315C, GLY400C, GLY59D, HIS352C, HIS356C, HIS399C, HIS403C, HIS404C, HIS52D, HIS56D, ILE244C, ILE247C, ILE338C, ILE348C, ILE351C, ILE405C, ILE54D, LEU272C, LEU279C, LEU354C, LEU357C, LEU367C, LEU408C, LEU65D, LEU68D, LEU88D, LEU91D, LYS250C, LYS274C, LYS310C, LYS316C, LYS321C, LYS353C, LYS355C, LYS90D, LYS97D, MET343C, MET347C, MET362C, MET363C, MET73D, MET86D, PHE251C, PHE275C, PHE314C, PHE350C, PHE370C, PHE392C, PHE69D, PHE95D, PHE96D, PRO342C, PRO358C, PRO81D, PRO85D, PRO92D, PRO98D, PRO99D, SER241C, SER308C, SER313C, SER341C, SER365C, SER395C, SER397C, SER61D, SER94D, THR306C, THR309C, THR324C, THR371C, THR63D, THR83D, TRP276C, TYR248C, TYR326C, TYR346C, TYR361C, TYR406C, VAL242C, VAL273C, VAL293C, VAL311C, VAL318C, VAL319C, VAL322C, VAL366C, VAL391C, VAL394C, VAL55D, VAL57D, VAL72D, VAL80D, VAL84D