3KVE

structure of native l-amino acid oxidase from vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 240
  • Norm. En. per Res.: -3.6821
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-52.2907	-417.4171	-405.116	-874.8238	239	38	5	22695	30	138	75
A-C	-4.7849	-8.3205	-27.1479	-40.2533	37	2	1	1527	1	12	16
A-D	-5.0538	-54.4631	-68.5695	-128.0863	64	1	0	2916	4	30	36
B-C	-8.5592	-46.7225	-70.2421	-125.5238	57	3	0	2839	4	29	33
B-D	0.0	-7.8632	-21.1704	-29.0336	46	2	1	1686	2	12	15
C-D	-61.6862	-433.6155	-388.401	-883.7027	240	33	4	22948	30	138	79

Interface residues

• A-B: ALA199A, ALA199B, ALA298A, ALA298B, ALA299A, ALA299B, ALA378A, ALA378B, ALA383A, ALA383B, ALA426A, ALA426B, ALA429A, ALA429B, ARG260A, ARG260B, ARG297A, ARG297B, ARG300A, ARG300B, ARG301A, ARG301B, ARG317A, ARG317B, ARG322A, ARG322B, ARG353A, ARG353B, ARG440A, ARG440B, ASN125A, ASN125B, ASN178A, ASN178B, ASN208A, ASN208B, ASN379A, ASN379B, ASN395A, ASN395B, ASP181A, ASP181B, ASP201A, ASP201B, ASP205A, ASP205B, ASP210A, ASP210B, ASP349A, ASP349B, ASP376A, ASP376B, ASP377A, ASP377B, ASP388A, ASP388B, ASP391A, ASP391B, ASP396A, ASP396B, ASP423A, ASP423B, CYS389A, CYS389B, GLN276A, GLN276B, GLN303A, GLN303B, GLN313A, GLN313B, GLN382A, GLN382B, GLN437A, GLN437B, GLN439A, GLN439B, GLU187A, GLU187B, GLU192A, GLU192B, GLU209A, GLU209B, GLY198A, GLY198B, GLY204A, GLY204B, GLY212A, GLY375A, GLY375B, GLY428A, GLY428B, HIS314A, HIS314B, HIS320A, HIS320B, ILE123A, ILE123B, ILE126A, ILE126B, ILE190A, ILE190B, ILE262A, ILE262B, ILE302A, ILE302B, ILE392A, ILE392B, LEU189A, LEU189B, LEU206A, LEU206B, LEU308A, LEU308B, LEU316A, LEU316B, LEU350A, LEU350B, LEU384A, LEU384B, LEU399A, LEU399B, LEU422A, LEU422B, LYS124A, LYS124B, LYS141A, LYS141B, LYS179A, LYS179B, LYS186A, LYS186B, LYS191A, LYS191B, LYS311A, LYS311B, LYS385A, LYS385B, LYS387A, LYS387B, LYS405A, LYS405B, LYS419A, LYS419B, LYS424A, LYS424B, MET202A, MET202B, MET427A, MET427B, PHE122A, PHE122B, PHE304A, PHE304B, PHE354A, PHE354B, PHE380A, PHE380B, PHE381A, PHE381B, PHE433A, PHE433B, PHE438A, PHE438B, PHE441A, PHE441B, PRO143A, PRO143B, PRO197A, PRO197B, PRO278B, PRO306A, PRO306B, PRO307A, PRO307B, PRO309A, PRO309B, PRO310A, PRO310B, PRO351A, PRO351B, PRO435A, PRO435B, SER184A, SER184B, SER196A, SER196B, SER211A, SER211B, SER216A, SER216B, SER296A, SER296B, SER318A, SER318B, SER323A, SER323B, SER352A, SER352B, SER421A, SER421B, THR182A, THR182B, THR185A, THR185B, THR347A, THR347B, THR348A, THR348B, THR432A, THR432B, THR434A, THR434B, TRP420A, TRP420B, TYR142A, TYR142B, TYR175B, TYR180A, TYR180B, TYR183A, TYR183B, TYR188A, TYR188B, TYR213A, TYR213B, TYR214A, TYR214B, TYR321A, TYR321B, TYR425A, TYR425B, TYR436A, TYR436B, VAL200A, VAL200B, VAL215A, VAL215B, VAL319A, VAL319B
• A-C: ALA390A, ARG76A, ASN395A, ASN395C, ASN77A, ASN77C, ASP391A, ASP391C, GLN409A, GLN409C, GLU406A, GLU406C, GLU80A, GLU80C, HIS75A, HIS75C, ILE392A, LYS387A, LYS387C, LYS405A, LYS405C, LYS79A, LYS79C, PHE394A, PHE394C, PRO414A, PRO414C, SER332A, SER332C, SER410A, SER410C, SER78C, THR364A, THR364C, TRP82C, TYR413A, TYR413C
• A-D: ALA84A, ALA84D, ARG249A, ARG249D, ARG67A, ARG67D, ARG73A, ARG73D, ARG76A, ARG76D, ASN258A, ASN258D, ASN77A, ASN77D, ASP241A, ASP241D, ASP281A, ASP281D, GLN242D, GLN276A, GLN276D, GLN303A, GLN303D, GLU252A, GLU253A, GLU253D, GLU279A, GLU279D, GLU66A, GLU66D, GLY81A, GLY81D, HIS75A, HIS75D, ILE262A, ILE262D, LEU86A, LEU86D, LYS263A, LYS280A, LYS280D, LYS79A, LYS79D, MET416A, MET416D, PHE257A, PHE257D, PRO278A, PRO278D, SER78A, SER78D, THR245A, THR245D, THR277A, THR277D, THR282A, THR282D, THR74A, THR74D, TRP82A, TYR248A, TYR248D, TYR83A, TYR83D
• B-C: ALA84B, ALA84C, ARG249B, ARG249C, ARG67B, ARG67C, ARG73B, ARG73C, ARG76B, ARG76C, ASN258B, ASN258C, ASN77B, ASN77C, ASP241B, ASP241C, ASP281B, ASP281C, GLN242C, GLN276B, GLN276C, GLU253B, GLU253C, GLU279B, GLU279C, GLU66B, GLU66C, GLY81B, GLY81C, HIS75B, HIS75C, ILE262B, ILE262C, LEU86B, LEU86C, LYS280B, LYS280C, LYS79B, LYS79C, MET416B, MET416C, PRO278B, PRO278C, SER78B, SER78C, THR245B, THR245C, THR277B, THR277C, THR282B, THR282C, THR74B, THR74C, TRP82B, TRP82C, TYR83B, TYR83C
• B-D: ARG76B, ASN395B, ASN395D, ASN77B, ASN77D, ASP388D, ASP391B, ASP391D, GLN409B, GLN409D, GLU406B, GLU406D, GLU80B, GLU80D, HIS75B, HIS75D, ILE392D, LYS387B, LYS387D, LYS405B, LYS405D, LYS79B, LYS79D, MET416B, MET416D, PHE386D, PHE394B, PHE394D, PHE411B, PRO414B, PRO414D, SER332B, SER332D, SER410B, SER410D, SER415B, SER415D, SER78B, THR364B, THR364D, TRP82B, TRP82D, TYR413B, TYR413D, VAL366B, VAL366D
• C-D: ALA199C, ALA199D, ALA298C, ALA298D, ALA299C, ALA299D, ALA378C, ALA378D, ALA383C, ALA383D, ALA426C, ALA426D, ALA429C, ALA429D, ARG260C, ARG260D, ARG297C, ARG297D, ARG300C, ARG300D, ARG301C, ARG301D, ARG317C, ARG317D, ARG322C, ARG322D, ARG353C, ARG353D, ARG440C, ARG440D, ASN125C, ASN125D, ASN178C, ASN178D, ASN208C, ASN208D, ASN379C, ASN379D, ASN395C, ASN395D, ASP181C, ASP181D, ASP201C, ASP201D, ASP205C, ASP205D, ASP210C, ASP210D, ASP349C, ASP349D, ASP376C, ASP376D, ASP377C, ASP377D, ASP388C, ASP388D, ASP391C, ASP391D, ASP396C, ASP396D, ASP423C, ASP423D, CYS389C, CYS389D, GLN276C, GLN303C, GLN303D, GLN313C, GLN313D, GLN382C, GLN382D, GLN437C, GLN437D, GLN439C, GLN439D, GLU187C, GLU187D, GLU192C, GLU192D, GLU209C, GLU209D, GLU279C, GLU279D, GLU305D, GLU66C, GLY198C, GLY198D, GLY204C, GLY204D, GLY212C, GLY212D, GLY375C, GLY375D, GLY428C, GLY428D, HIS314C, HIS314D, HIS320C, HIS320D, ILE123C, ILE123D, ILE126C, ILE126D, ILE190C, ILE190D, ILE262C, ILE262D, ILE302C, ILE302D, ILE392C, ILE392D, LEU189C, LEU189D, LEU206C, LEU206D, LEU308C, LEU308D, LEU316C, LEU316D, LEU350C, LEU350D, LEU384C, LEU384D, LEU399C, LEU399D, LEU422C, LEU422D, LYS124C, LYS124D, LYS141C, LYS141D, LYS179C, LYS179D, LYS186C, LYS186D, LYS191C, LYS191D, LYS311C, LYS311D, LYS385C, LYS385D, LYS387C, LYS387D, LYS405C, LYS419C, LYS419D, LYS424C, LYS424D, MET202C, MET202D, MET427C, MET427D, PHE122C, PHE122D, PHE304C, PHE304D, PHE354C, PHE354D, PHE380C, PHE380D, PHE381C, PHE381D, PHE433C, PHE433D, PHE441C, PHE441D, PRO143C, PRO143D, PRO197C, PRO197D, PRO278D, PRO306D, PRO307C, PRO307D, PRO309C, PRO309D, PRO310C, PRO310D, PRO351C, PRO351D, PRO435C, PRO435D, SER184C, SER184D, SER196C, SER196D, SER211C, SER211D, SER216C, SER216D, SER296C, SER296D, SER318C, SER318D, SER323C, SER323D, SER352C, SER352D, SER398C, SER421C, SER421D, THR182C, THR182D, THR185C, THR185D, THR295C, THR347C, THR347D, THR348C, THR348D, THR432C, THR432D, THR434C, THR434D, TRP420C, TRP420D, TYR142C, TYR142D, TYR180C, TYR180D, TYR183C, TYR183D, TYR188C, TYR188D, TYR213C, TYR213D, TYR214C, TYR214D, TYR321C, TYR321D, TYR425C, TYR425D, TYR436C, TYR436D, VAL200C, VAL200D, VAL215C, VAL215D, VAL319C, VAL319D