3KR3

crystal structure of igf-ii antibody complex

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: D-H
  • Int. Res.: 74
  • Norm. En. per Res.: -3.7445
• Hub Node: D(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
D-H	-29.1881	-38.1665	-209.736	-277.0907	74	8	4	7745	2	17	14
D-L	-22.4209	0.0	-83.1931	-105.614	30	2	0	2365	0	0	1
H-L	-26.6685	-8.8581	-443.233	-478.7596	180	16	10	17775	1	19	17

Interface residues

• D-H: ALA32D, ARG30D, ARG34D, ARG37D, ARG40D, ARG49D, ARG59H, ARG72H, ARG98H, ASN100H, ASN31H, ASN74H, ASP102H, ASP15D, ASP99H, CYS46D, CYS47D, CYS51D, CYS9D, GLN18D, GLU106H, GLU12D, GLU44D, GLU45D, GLU6D, GLY101H, GLY105H, GLY108H, GLY10D, GLY11D, GLY41D, GLY55H, GLY56H, ILE33H, ILE42D, ILE51H, ILE70H, LEU13D, LEU17D, LEU55D, LEU8D, LYS107H, MET34H, MET57H, PHE109H, PHE26D, PHE28D, PHE48D, PRO31D, SER29D, SER30H, SER33D, SER36D, SER39D, SER49H, SER50D, SER52H, SER53H, SER54H, SER5D, THR28H, THR58H, THR7D, TRP35H, TRP47H, TYR103H, TYR32H, TYR59D, TYR60H, VAL104H, VAL14D, VAL35D, VAL43D, VAL50H
• D-L: ASN32L, ASN94L, ASP15D, CYS47D, CYS9D, GLN18D, GLN1L, GLN91L, GLU12D, GLY10D, GLY11D, ILE30L, ILE3L, LEU13D, LEU8D, PHE26D, PHE48D, PRO96L, SER29L, SER31L, SER5D, SER92L, SER95L, THR16D, THR51L, THR7D, TRP97L, TYR33L, TYR93L, VAL14D
• H-L: ALA131L, ALA134H, ALA145H, ALA146H, ALA177H, ALA44L, ALA52L, ALA61H, ALA97H, ARG143L, ARG38H, ARG59H, ARG98H, ASN100H, ASN138L, ASN139L, ASN32L, ASN35L, ASN94L, ASP110H, ASP123L, ASP153H, ASP168L, ASP171L, ASP2L, ASP62H, ASP99H, CYS135L, CYS149H, CYS89L, CYS96H, GLN101L, GLN114H, GLN125L, GLN161L, GLN166L, GLN180H, GLN38L, GLN39H, GLN39L, GLN56L, GLN90L, GLN91L, GLU106H, GLU124L, GLU162L, GLU167L, GLU214L, GLU46H, GLU6H, GLY100L, GLY101H, GLY102L, GLY105H, GLY108H, GLY113H, GLY115H, GLY148H, GLY171H, GLY42H, GLY42L, GLY44H, HIS173H, ILE111H, ILE118L, ILE33H, ILE49L, LEU126L, LEU133H, LEU136L, LEU137L, LEU147H, LEU150H, LEU176L, LEU179H, LEU182L, LEU184H, LEU187H, LEU34L, LEU45H, LEU47L, LEU48L, LYS107H, LYS127L, LYS152H, LYS170L, LYS208L, LYS218H, LYS219H, LYS223H, LYS40L, LYS43H, LYS43L, LYS46L, LYS65H, PHE109H, PHE117L, PHE119L, PHE131H, PHE140L, PHE175H, PHE210L, PHE99L, PRO120L, PRO121L, PRO132H, PRO135H, PRO176H, PRO41L, PRO45L, PRO96L, SER115L, SER122L, SER128L, SER129H, SER132L, SER136H, SER137H, SER160L, SER163L, SER169L, SER170H, SER175L, SER177L, SER178L, SER181H, SER182H, SER186H, SER188H, SER189H, SER209L, SER49H, SER57L, SER88L, SER92L, SER95L, THR130L, THR144H, THR165L, THR173L, THR174H, THR179L, THR181L, THR192H, THR51L, THR54L, THR86L, THR98L, TRP112H, TRP35H, TRP36H, TRP36L, TRP47H, TRP97L, TYR103H, TYR174L, TYR185H, TYR33L, TYR37L, TYR50L, TYR60H, TYR93L, TYR95H, VAL104H, VAL116L, VAL130H, VAL133L, VAL134L, VAL151H, VAL164L, VAL172H, VAL178H, VAL190H, VAL191H, VAL193H, VAL220H, VAL37H, VAL48H, VAL50H, VAL93H