3KL2

crystal structure of a putative isochorismatase from streptomyces avermitilis

• Total interactions analyzed: 66
• Total true interactions: 23
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 91
  • Norm. En. per Res.: -4.3064
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-117.2007	62.7267	-341.88	-396.354	127	27	3	12422	2	30	47
A-C	-63.6837	-59.353	-241.754	-364.7907	93	10	3	9366	11	22	37
A-D	0.0	19.5224	-49.774	-30.2516	36	3	0	2259	0	20	23
A-E	0.0	-2.1486	-40.6677	-42.8163	36	0	0	1477	0	10	10
A-G	0.0	0.0	-0.0128	-0.0128	3	0	0	10	0	0	0
B-C	0.0	26.3618	-50.0484	-23.6866	35	1	0	2146	0	20	22
B-D	-61.7956	-80.0236	-250.061	-391.8802	91	13	4	9516	10	22	36
C-D	-101.8208	60.1696	-364.647	-406.2982	128	26	4	12684	3	26	46
C-G	0.0	-3.0549	-44.5368	-47.5917	39	0	0	1607	0	9	10
E-F	-119.135	67.1128	-341.313	-393.3352	126	32	3	12163	3	28	46
E-G	-68.7645	-51.6398	-253.818	-374.2223	96	11	4	9624	8	22	35
E-H	0.0	19.3377	-58.78	-39.4423	37	3	0	2381	0	20	23
F-G	0.0	18.8838	-54.8831	-35.9993	36	1	0	2306	0	20	23
F-H	-73.6722	-61.7542	-255.377	-390.8034	97	9	4	9755	10	22	36
G-H	-112.0487	57.101	-357.632	-412.5797	125	22	3	12468	2	29	47
H-I	-11.978	0.0	-47.4657	-59.4437	41	2	0	1983	0	7	11
H-K	0.0	12.2855	-46.7342	-34.4487	31	0	0	1707	0	10	12
I-J	-99.4446	49.5275	-347.881	-397.7981	125	15	3	11934	3	29	47
I-K	-54.6173	-70.3671	-247.043	-372.0274	93	12	4	9485	8	22	37
I-L	0.0	25.2093	-53.0061	-27.7968	35	1	0	2252	0	20	23
J-K	0.0	20.8748	-56.963	-36.0882	38	5	0	2325	0	20	24
J-L	-49.529	-61.2243	-239.231	-349.9843	94	6	4	9480	7	22	36
K-L	-90.5404	64.1589	-352.816	-379.1975	126	20	3	12279	2	26	47

Interface residues

• A-B: ALA155A, ALA155B, ALA205A, ALA205B, ALA214A, ALA214B, ARG149A, ARG149B, ARG187A, ARG187B, ARG192A, ARG192B, ARG195A, ARG195B, ASN179A, ASN179B, ASN212A, ASN212B, ASN213A, ASN213B, ASP152A, ASP152B, ASP169A, ASP169B, ASP218A, ASP218B, CYS180A, CYS180B, CYS181A, CYS181B, GLN208A, GLN208B, GLU183A, GLU183B, GLU191A, GLU191B, GLU209A, GLU209B, GLU210A, GLU210B, GLY112A, GLY112B, GLY116A, GLY116B, GLY150A, GLY150B, GLY189A, GLY189B, GLY193A, GLY193B, HIS211A, HIS211B, ILE113A, ILE113B, ILE171A, ILE171B, ILE197A, ILE197B, LEU106A, LEU106B, LEU114A, LEU114B, LEU151A, LEU151B, LEU177A, LEU177B, LYS115A, LYS115B, LYS148A, LYS148B, MET186A, MET186B, MET221A, MET221B, PHE154A, PHE154B, PHE194A, PHE194B, PHE219A, PHE219B, PHE222A, PHE222B, PRO110A, PRO110B, PRO220A, PRO220B, PRO225A, PRO225B, SER156A, SER156B, SER184A, SER184B, SER207A, SER207B, SER216A, SER216B, SER223A, SER223B, THR107A, THR107B, THR153A, THR153B, THR170A, THR170B, THR178A, THR178B, THR185A, THR185B, THR188A, THR188B, THR198A, THR198B, THR206A, THR206B, TYR111A, TYR111B, TYR190A, TYR190B, TYR217A, TYR217B, VAL117A, VAL182A, VAL182B, VAL196A, VAL196B, VAL224A, VAL224B
• A-C: ALA100A, ALA100C, ALA155A, ALA155C, ALA41C, ARG108A, ARG108C, ARG149A, ARG149C, ARG164A, ARG164C, ARG192A, ARG192C, ASN158A, ASN158C, ASP142A, ASP142C, ASP152A, ASP152C, ASP160A, ASP160C, GLU101A, GLU101C, GLU105A, GLU105C, GLU146A, GLU146C, GLY102A, GLY102C, GLY104A, GLY104C, GLY141A, GLY141C, GLY147A, GLY147C, GLY150A, GLY150C, GLY167A, GLY167C, HIS109A, HIS109C, ILE143A, ILE143C, ILE145A, ILE145C, ILE162A, ILE162C, ILE97A, ILE97C, LEU106A, LEU106C, LEU114A, LEU114C, LEU151A, LEU151C, LEU159A, LEU159C, LEU163A, LEU163C, LYS125A, LYS125C, LYS148A, LYS148C, LYS166A, LYS166C, MET93A, MET93C, PHE154A, PHE154C, PHE161A, PHE161C, PHE99A, PHE99C, PRO110A, PRO110C, PRO91A, PRO91C, PRO96A, PRO96C, SER156A, SER156C, SER165A, SER165C, THR107A, THR107C, THR157A, THR157C, THR98A, THR98C, TYR103A, TYR103C, VAL144A, VAL144C
• A-D: ARG164A, ARG164D, ARG187A, ARG187D, ARG192A, ARG192D, ARG42A, ARG42D, ASP160A, ASP160D, ASP169A, ASP169D, GLU191A, GLU191D, GLY167A, GLY167D, GLY189A, GLY189D, GLY193A, GLY193D, ILE162A, ILE162D, LEU163A, LEU163D, LYS166A, LYS166D, PHE161A, PHE161D, PHE194A, PHE194D, SER165A, SER165D, TYR190A, TYR190D, VAL168A, VAL168D
• A-E: ALA130A, ALA131A, ALA131E, ALA137A, ASN140A, ASN52A, ASN52E, ASP134A, ASP134E, ASP57A, ASP57E, GLU101A, GLU101E, GLU135A, GLU53E, GLY102E, GLY120E, GLY126A, GLY129A, GLY129E, GLY58A, GLY58E, GLY59E, ILE132A, LYS121E, LYS125A, PRO138A, SER56A, SER56E, THR127A, THR127E, TRP128A, TRP128E, VAL124E, VAL139A, VAL60E
• A-G: ASN140A, ASN140G, GLY141G
• B-C: ARG164B, ARG164C, ARG187C, ARG192B, ARG192C, ARG42C, ASP160B, ASP160C, ASP169B, ASP169C, GLU191B, GLU191C, GLY167B, GLY167C, GLY189B, GLY189C, GLY193B, GLY193C, ILE162B, ILE162C, LEU163B, LEU163C, LYS166B, LYS166C, PHE161B, PHE161C, PHE194B, PHE194C, SER165B, SER165C, THR188C, TYR190B, TYR190C, VAL168B, VAL168C
• B-D: ALA100B, ALA100D, ALA155B, ALA155D, ARG108B, ARG108D, ARG149B, ARG149D, ARG164B, ARG164D, ARG192B, ARG192D, ASN158B, ASN158D, ASP142B, ASP142D, ASP152B, ASP152D, ASP160B, ASP160D, GLU101B, GLU101D, GLU105B, GLU105D, GLU146B, GLU146D, GLY102D, GLY104B, GLY104D, GLY141B, GLY141D, GLY147B, GLY147D, GLY150B, GLY150D, GLY167B, GLY167D, HIS109B, HIS109D, ILE143B, ILE143D, ILE145B, ILE145D, ILE162B, ILE162D, ILE97B, ILE97D, LEU106B, LEU106D, LEU114B, LEU114D, LEU151B, LEU151D, LEU159B, LEU159D, LEU163B, LEU163D, LYS125B, LYS125D, LYS148B, LYS148D, LYS166B, LYS166D, MET93B, MET93D, PHE154B, PHE154D, PHE161B, PHE161D, PHE99B, PHE99D, PRO110B, PRO110D, PRO91B, PRO91D, PRO96B, PRO96D, SER156B, SER156D, SER165B, SER165D, THR107B, THR107D, THR157B, THR157D, THR98B, THR98D, TYR103B, TYR103D, VAL144B, VAL144D
• C-D: ALA155C, ALA155D, ALA205C, ALA205D, ALA214C, ALA214D, ARG149C, ARG149D, ARG187C, ARG187D, ARG192C, ARG192D, ARG195C, ARG195D, ASN179C, ASN179D, ASN212C, ASN212D, ASN213C, ASN213D, ASP152C, ASP152D, ASP169C, ASP169D, ASP218C, ASP218D, CYS180C, CYS180D, CYS181C, CYS181D, GLN208C, GLU183C, GLU183D, GLU191C, GLU191D, GLU209C, GLU209D, GLU210C, GLU210D, GLY112C, GLY112D, GLY116C, GLY116D, GLY150C, GLY150D, GLY189C, GLY189D, GLY193C, GLY193D, HIS211C, HIS211D, ILE113C, ILE113D, ILE171C, ILE171D, ILE197C, ILE197D, LEU106C, LEU106D, LEU114C, LEU114D, LEU151C, LEU151D, LEU177C, LEU177D, LYS115C, LYS115D, LYS148C, LYS148D, MET186C, MET186D, MET221C, MET221D, PHE154C, PHE154D, PHE194C, PHE194D, PHE219C, PHE219D, PHE222C, PHE222D, PHE54C, PRO110C, PRO110D, PRO220C, PRO220D, PRO225C, PRO225D, SER156C, SER156D, SER184C, SER184D, SER207C, SER207D, SER216C, SER216D, SER223C, SER223D, THR107C, THR107D, THR153C, THR153D, THR170C, THR170D, THR178C, THR178D, THR185C, THR185D, THR188C, THR188D, THR198C, THR198D, THR206C, THR206D, TYR111C, TYR111D, TYR190C, TYR190D, TYR217C, TYR217D, VAL117C, VAL117D, VAL182C, VAL182D, VAL196C, VAL196D, VAL224C, VAL224D
• C-G: ALA130G, ALA131C, ALA131G, ALA137G, ASN140G, ASN52C, ASN52G, ASP134C, ASP134G, ASP57C, ASP57G, GLU101C, GLU101G, GLU135G, GLU53C, GLY102C, GLY120C, GLY126G, GLY129C, GLY129G, GLY141G, GLY58C, GLY58G, GLY59C, ILE132G, LEU136G, LYS121C, LYS125G, PRO138G, SER56C, SER56G, THR127C, THR127G, TRP128C, TRP128G, VAL124C, VAL124G, VAL139G, VAL60C
• E-F: ALA155E, ALA155F, ALA205E, ALA205F, ALA214E, ALA214F, ARG149E, ARG149F, ARG187E, ARG187F, ARG192E, ARG192F, ARG195E, ARG195F, ASN179E, ASN179F, ASN212E, ASN212F, ASN213E, ASN213F, ASP152E, ASP152F, ASP169E, ASP169F, ASP218E, ASP218F, CYS180E, CYS180F, CYS181E, CYS181F, GLN208F, GLU183E, GLU183F, GLU191E, GLU191F, GLU209E, GLU209F, GLU210E, GLU210F, GLY112E, GLY112F, GLY116E, GLY116F, GLY150E, GLY150F, GLY189E, GLY189F, GLY193E, GLY193F, HIS109E, HIS211F, ILE113E, ILE113F, ILE171E, ILE171F, ILE197E, ILE197F, LEU106E, LEU106F, LEU114E, LEU114F, LEU151E, LEU151F, LEU177E, LEU177F, LYS115E, LYS115F, LYS148E, LYS148F, MET186E, MET186F, MET221E, MET221F, PHE154E, PHE154F, PHE194E, PHE194F, PHE219E, PHE219F, PHE222E, PHE222F, PRO110E, PRO110F, PRO220E, PRO220F, PRO225E, PRO225F, SER156E, SER156F, SER184E, SER184F, SER207E, SER207F, SER216E, SER216F, SER223E, SER223F, THR107E, THR107F, THR153E, THR153F, THR170E, THR170F, THR178E, THR178F, THR185E, THR185F, THR188E, THR188F, THR198E, THR198F, THR206E, THR206F, TYR111E, TYR111F, TYR190E, TYR190F, TYR217E, TYR217F, VAL117F, VAL182E, VAL182F, VAL196E, VAL196F, VAL224E, VAL224F
• E-G: ALA100E, ALA100G, ALA155E, ALA155G, ALA41G, ARG108E, ARG108G, ARG149E, ARG149G, ARG164E, ARG164G, ARG192E, ARG192G, ARG42G, ASN158E, ASN158G, ASP142E, ASP142G, ASP152E, ASP152G, ASP160E, ASP160G, GLU101E, GLU101G, GLU105E, GLU105G, GLU146E, GLU146G, GLY102G, GLY104E, GLY104G, GLY141E, GLY141G, GLY147E, GLY147G, GLY150E, GLY150G, GLY167E, GLY167G, GLY89G, HIS109E, HIS109G, ILE143E, ILE143G, ILE145E, ILE145G, ILE162E, ILE162G, ILE97E, ILE97G, LEU106E, LEU106G, LEU114E, LEU114G, LEU151E, LEU151G, LEU159E, LEU159G, LEU163E, LEU163G, LYS125E, LYS125G, LYS148E, LYS148G, LYS166E, LYS166G, MET93E, MET93G, PHE154E, PHE154G, PHE161E, PHE161G, PHE99E, PHE99G, PRO110E, PRO110G, PRO40G, PRO91E, PRO91G, PRO96E, PRO96G, SER156E, SER156G, SER165E, SER165G, THR107E, THR107G, THR157E, THR157G, THR98E, THR98G, TYR103E, TYR103G, TYR111E, VAL144E, VAL144G
• E-H: ARG164E, ARG164H, ARG187E, ARG187H, ARG192E, ARG192H, ARG42E, ARG42H, ASP160E, ASP160H, ASP169E, ASP169H, GLU191E, GLU191H, GLY167E, GLY167H, GLY189E, GLY189H, GLY193E, GLY193H, ILE162E, ILE162H, LEU163E, LEU163H, LYS166E, LYS166H, PHE161E, PHE161H, PHE194E, PHE194H, SER165E, SER165H, THR188E, TYR190E, TYR190H, VAL168E, VAL168H
• F-G: ARG164F, ARG164G, ARG187F, ARG187G, ARG192F, ARG192G, ARG42F, ARG42G, ASP160F, ASP160G, ASP169F, ASP169G, GLU191F, GLU191G, GLY167F, GLY167G, GLY189F, GLY189G, GLY193F, GLY193G, ILE162F, ILE162G, LEU163F, LEU163G, LYS166F, LYS166G, PHE161F, PHE161G, PHE194F, PHE194G, SER165F, SER165G, TYR190F, TYR190G, VAL168F, VAL168G
• F-H: ALA100F, ALA100H, ALA155F, ALA155H, ALA41F, ALA41H, ARG108F, ARG108H, ARG149F, ARG149H, ARG164F, ARG164H, ARG192F, ARG192H, ASN158F, ASN158H, ASP142F, ASP142H, ASP152F, ASP152H, ASP160F, ASP160H, GLU101F, GLU101H, GLU105F, GLU105H, GLU146F, GLU146H, GLY102F, GLY102H, GLY104F, GLY104H, GLY141F, GLY141H, GLY147F, GLY147H, GLY150F, GLY150H, GLY167F, GLY167H, HIS109F, HIS109H, ILE143F, ILE143H, ILE145F, ILE145H, ILE162F, ILE162H, ILE97F, ILE97H, LEU106F, LEU106H, LEU114F, LEU114H, LEU151F, LEU151H, LEU159F, LEU159H, LEU163F, LEU163H, LYS125F, LYS125H, LYS148F, LYS148H, LYS166F, LYS166H, MET93F, MET93H, PHE154F, PHE154H, PHE161F, PHE161H, PHE99F, PHE99H, PRO110F, PRO110H, PRO91F, PRO91H, PRO96F, PRO96H, SER156F, SER156H, SER165F, SER165H, THR107F, THR107H, THR157F, THR157H, THR98F, THR98H, TYR103F, TYR103H, TYR111F, TYR111H, VAL118F, VAL144F, VAL144H
• G-H: ALA155G, ALA155H, ALA205G, ALA205H, ALA214G, ALA214H, ARG149G, ARG149H, ARG187G, ARG187H, ARG192G, ARG192H, ARG195G, ARG195H, ASN179G, ASN179H, ASN212H, ASN213G, ASN213H, ASP152G, ASP152H, ASP169G, ASP169H, ASP218G, ASP218H, CYS180G, CYS180H, CYS181G, CYS181H, GLU183G, GLU183H, GLU191G, GLU191H, GLU209G, GLU209H, GLU210G, GLU210H, GLY112G, GLY112H, GLY116G, GLY116H, GLY150G, GLY150H, GLY189G, GLY189H, GLY193G, GLY193H, HIS211G, HIS211H, ILE113G, ILE113H, ILE171G, ILE171H, ILE197G, ILE197H, LEU106G, LEU106H, LEU114G, LEU114H, LEU151G, LEU151H, LEU177G, LEU177H, LYS115G, LYS115H, LYS148G, LYS148H, MET186G, MET186H, MET221G, MET221H, PHE154G, PHE154H, PHE194G, PHE194H, PHE219G, PHE219H, PHE222G, PHE222H, PRO110G, PRO110H, PRO220G, PRO220H, PRO225G, PRO225H, SER156G, SER156H, SER184G, SER184H, SER207G, SER207H, SER216G, SER216H, SER223G, SER223H, THR107G, THR107H, THR153G, THR153H, THR170G, THR170H, THR178G, THR178H, THR185G, THR185H, THR188G, THR188H, THR198G, THR198H, THR206G, THR206H, TYR111G, TYR111H, TYR190G, TYR190H, TYR217G, TYR217H, VAL117G, VAL117H, VAL182G, VAL182H, VAL196G, VAL196H, VAL224G, VAL224H
• H-I: ALA130I, ALA131I, ALA137H, ALA137I, ALA76H, ALA80H, ALA84H, ALA85H, ALA88H, ARG86H, ASN140H, ASN52I, ASP134H, ASP134I, ASP142H, ASP57I, ASP83H, GLN87H, GLU101I, GLU135H, GLU53I, GLY126I, GLY129I, GLY141H, GLY58I, GLY59I, ILE132I, ILE232H, LEU136H, LYS121I, LYS125I, PRO138H, SER56I, THR127I, TRP128I, VAL124I, VAL139H, VAL60I, VAL79H, VAL81H, VAL82H
• H-K: ALA130H, ALA130K, ALA131H, ALA131K, ALA137K, ASN52H, ASN52K, ASP134H, ASP134K, ASP57H, GLU101K, GLU135H, GLU135K, GLY126H, GLY126K, GLY129H, GLY129K, GLY58H, GLY59H, ILE132K, LYS125K, SER56H, THR127H, THR127K, THR55H, THR98K, TRP128H, TRP128K, VAL124K, VAL133H, VAL133K
• I-J: ALA155I, ALA155J, ALA205I, ALA205J, ALA214I, ALA214J, ARG149I, ARG149J, ARG187I, ARG187J, ARG192I, ARG192J, ARG195I, ARG195J, ASN179I, ASN179J, ASN212I, ASN213I, ASN213J, ASP152I, ASP152J, ASP169I, ASP169J, ASP218I, ASP218J, CYS180I, CYS180J, CYS181I, CYS181J, GLN208I, GLU183I, GLU183J, GLU191I, GLU191J, GLU209I, GLU209J, GLU210I, GLU210J, GLY112I, GLY112J, GLY116I, GLY116J, GLY150I, GLY150J, GLY189I, GLY189J, GLY193I, GLY193J, HIS211I, ILE113I, ILE113J, ILE171I, ILE171J, ILE197I, ILE197J, LEU106I, LEU106J, LEU114I, LEU114J, LEU151I, LEU151J, LEU177I, LEU177J, LYS115I, LYS115J, LYS148I, LYS148J, MET186I, MET186J, MET221I, MET221J, PHE154I, PHE154J, PHE194I, PHE194J, PHE219I, PHE219J, PHE222I, PHE222J, PRO110I, PRO110J, PRO220I, PRO220J, PRO225I, PRO225J, SER156I, SER156J, SER184I, SER184J, SER207I, SER207J, SER216I, SER216J, SER223I, SER223J, THR107I, THR107J, THR153I, THR153J, THR170I, THR170J, THR178I, THR178J, THR185I, THR185J, THR188I, THR188J, THR198I, THR198J, THR206I, THR206J, TYR111I, TYR111J, TYR190I, TYR190J, TYR217I, TYR217J, VAL117I, VAL117J, VAL182I, VAL182J, VAL196I, VAL196J, VAL224I, VAL224J
• I-K: ALA100I, ALA100K, ALA155I, ALA155K, ARG108I, ARG108K, ARG149I, ARG149K, ARG164I, ARG164K, ARG192I, ARG192K, ASN158I, ASN158K, ASP142I, ASP142K, ASP152I, ASP152K, ASP160I, ASP160K, GLU101I, GLU101K, GLU105I, GLU105K, GLU146I, GLU146K, GLY104I, GLY104K, GLY141I, GLY141K, GLY147I, GLY147K, GLY150I, GLY150K, GLY167I, GLY167K, HIS109I, HIS109K, ILE113I, ILE143I, ILE143K, ILE145I, ILE145K, ILE162I, ILE162K, ILE97I, ILE97K, LEU106I, LEU106K, LEU114I, LEU114K, LEU151I, LEU151K, LEU159I, LEU159K, LEU163I, LEU163K, LYS125I, LYS125K, LYS148I, LYS148K, LYS166I, LYS166K, MET93I, MET93K, PHE154I, PHE154K, PHE161I, PHE161K, PHE99I, PHE99K, PRO110I, PRO110K, PRO91I, PRO91K, PRO96I, PRO96K, SER156I, SER156K, SER165I, SER165K, THR107I, THR107K, THR157I, THR157K, THR98I, THR98K, TYR103I, TYR103K, TYR111I, TYR111K, VAL144I, VAL144K
• I-L: ARG164I, ARG164L, ARG187I, ARG192I, ARG192L, ARG42I, ARG42L, ASP160I, ASP160L, ASP169I, ASP169L, GLU191I, GLU191L, GLY167I, GLY167L, GLY189I, GLY189L, GLY193I, GLY193L, ILE162I, ILE162L, LEU163I, LEU163L, LYS166I, LYS166L, PHE161I, PHE161L, PHE194I, PHE194L, SER165I, SER165L, TYR190I, TYR190L, VAL168I, VAL168L
• J-K: ARG164J, ARG164K, ARG187J, ARG187K, ARG192J, ARG192K, ARG42J, ARG42K, ASP160J, ASP160K, ASP169J, ASP169K, GLU191J, GLU191K, GLY167J, GLY167K, GLY189J, GLY189K, GLY193J, GLY193K, ILE162J, ILE162K, LEU163J, LEU163K, LYS166J, LYS166K, PHE161J, PHE161K, PHE194J, PHE194K, SER165J, SER165K, THR188J, THR188K, TYR190J, TYR190K, VAL168J, VAL168K
• J-L: ALA100J, ALA100L, ALA155J, ALA155L, ALA41J, ALA41L, ARG108J, ARG108L, ARG149J, ARG149L, ARG164J, ARG164L, ARG192J, ARG192L, ASN140J, ASN158J, ASN158L, ASP142J, ASP142L, ASP152J, ASP152L, ASP160J, ASP160L, GLU101J, GLU101L, GLU105J, GLU105L, GLU146J, GLU146L, GLY104J, GLY104L, GLY141J, GLY141L, GLY147J, GLY147L, GLY150J, GLY150L, GLY167J, GLY167L, HIS109J, HIS109L, ILE143J, ILE143L, ILE145J, ILE145L, ILE162J, ILE162L, ILE97J, ILE97L, LEU106J, LEU106L, LEU114J, LEU114L, LEU151J, LEU151L, LEU159J, LEU159L, LEU163J, LEU163L, LYS125J, LYS125L, LYS148J, LYS148L, LYS166J, LYS166L, MET93J, MET93L, PHE154J, PHE154L, PHE161J, PHE161L, PHE99J, PHE99L, PRO110J, PRO110L, PRO91J, PRO91L, PRO96J, PRO96L, SER156J, SER156L, SER165J, SER165L, THR107J, THR107L, THR157J, THR157L, THR98J, THR98L, TYR103J, TYR103L, TYR111L, VAL144J, VAL144L
• K-L: ALA155K, ALA155L, ALA205K, ALA205L, ALA214K, ALA214L, ARG149K, ARG149L, ARG187K, ARG187L, ARG192K, ARG192L, ARG195K, ARG195L, ASN179K, ASN179L, ASN212K, ASN212L, ASN213K, ASN213L, ASP152K, ASP152L, ASP169K, ASP169L, ASP218K, ASP218L, CYS180K, CYS180L, CYS181K, CYS181L, GLN208L, GLU183K, GLU183L, GLU191K, GLU191L, GLU209K, GLU209L, GLU210K, GLU210L, GLY112K, GLY112L, GLY116K, GLY116L, GLY150K, GLY150L, GLY189K, GLY189L, GLY193K, GLY193L, HIS211K, HIS211L, ILE113K, ILE113L, ILE171K, ILE171L, ILE197K, ILE197L, LEU106K, LEU106L, LEU114K, LEU114L, LEU151K, LEU151L, LEU177K, LEU177L, LYS115K, LYS115L, LYS148K, LYS148L, MET186K, MET186L, MET221K, MET221L, PHE154K, PHE154L, PHE194K, PHE194L, PHE219K, PHE219L, PHE222K, PHE222L, PRO110K, PRO110L, PRO220K, PRO220L, PRO225K, PRO225L, SER156K, SER156L, SER184K, SER184L, SER207K, SER207L, SER216K, SER216L, SER223K, SER223L, THR107K, THR107L, THR153K, THR153L, THR170K, THR170L, THR178K, THR178L, THR185K, THR185L, THR188K, THR188L, THR198K, THR198L, THR206K, THR206L, TYR111K, TYR111L, TYR190K, TYR190L, TYR217K, TYR217L, VAL117L, VAL182K, VAL182L, VAL196K, VAL196L, VAL224K, VAL224L