3KKA

co-crystal structure of the sam domains of epha1 and epha2

• Total interactions analyzed: 10
• Total true interactions: 7
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 25
  • Norm. En. per Res.: -4.4424
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-37.3845	0.0	-139.845	-177.2295	55	6	0	5302	2	7	6
A-D	-4.9773	-38.1652	-31.0806	-74.2231	25	2	1	1513	2	7	4
A-E	-31.5088	-19.5013	-60.0492	-111.0592	25	3	0	2098	1	8	7
B-C	-7.6464	20.4461	-15.1225	-2.3228	22	2	0	758	0	6	5
B-E	0.0	0.0	-0.2204	-0.2204	9	0	0	61	0	3	3
C-E	-13.2714	10.1471	-59.1558	-62.2801	35	1	2	2353	0	6	9
D-E	-5.5573	-2.7371	-64.1404	-72.4348	48	0	0	3189	4	11	12

Interface residues

• A-B: ARG916A, ARG916B, ARG926A, ARG926B, ARG929A, ARG929B, ARG966A, ARG966B, CYS969A, CYS969B, GLN964A, GLN964B, GLN972A, GLN972B, GLU920A, GLU920B, GLU923A, GLU923B, GLY912A, GLY912B, GLY962A, GLY962B, GLY973A, GLY973B, HIS963A, HIS963B, ILE913A, ILE913B, ILE925A, ILE925B, ILE967A, ILE967B, ILE971A, ILE971B, LEU922B, LEU968A, LEU968B, LYS965A, LYS965B, MET927A, MET927B, PHE974A, PHE974B, PRO914A, PRO914B, SER924A, SER924B, SER970A, SER970B, THR917A, THR917B, TRP921A, TRP921B, TYR915A, TYR915B
• A-D: ALA932D, ARG929A, ASN970D, GLN938D, GLN964A, GLU934D, GLY903D, GLY957A, GLY962A, HIS933A, HIS963A, ILE933D, ILE958A, LEU960A, LEU965D, LYS935D, LYS966D, MET927A, PRO961A, THR959A, TYR930A, VAL904D, VAL936D, VAL937D, VAL969D
• A-E: ALA959E, ARG926A, ARG929A, ARG966A, ASN941E, ASP967E, GLN968E, GLU923A, GLY964E, HIS933A, ILE925A, ILE931A, LEU922A, LEU932A, LEU962E, LEU963E, LEU965E, LYS928A, LYS956E, LYS966E, MET927A, SER924A, SER961E, TYR930A, TYR960E
• B-C: ALA931C, ARG916B, ASP940B, CYS944B, GLU910C, GLU920B, GLU933C, GLU943B, GLY912B, ILE932C, LYS934C, MET925C, MET942B, SER909C, SER919B, THR907C, THR917B, THR930C, THR941B, TYR915B, VAL908C, VAL918B
• B-E: ARG916B, ASP967E, GLN968E, GLU920B, GLY903E, GLY912B, ILE913B, PRO914B, TYR915B
• C-E: ALA926C, ALA927C, ALA932E, ARG907E, ARG945C, GLN918C, GLN919C, GLN968E, GLU911E, GLU922C, GLU934E, GLY903E, GLY928C, GLY947C, HIS923C, ILE933E, ILE943C, ILE946C, LYS935E, LYS944C, MET925C, PHE906E, PHE924C, PRO905E, THR908E, THR921C, THR930C, THR931E, TYR920C, TYR929C, VAL904E, VAL909E, VAL936E, VAL937E, VAL948C
• D-E: ALA927D, ALA928D, ALA932D, ARG907D, ARG957E, ASP967E, GLN919D, GLN919E, GLN920D, GLN920E, GLU911D, GLU911E, GLU914D, GLU914E, GLU923D, GLU934D, GLY929D, GLY953E, GLY964E, HIS924D, HIS954E, ILE916E, ILE933D, ILE958E, LEU913D, LEU962E, LEU963E, LEU965E, LYS917E, LYS935D, LYS956E, MET918E, MET926D, PHE906D, PHE906E, PHE925D, PRO905E, SER910D, SER915E, SER961E, THR908D, THR922D, THR931D, TRP912E, TYR930D, TYR960E, VAL904E, VAL909D